Scientific Commons: D. G.

Heat shock proteins (HSPs) have been reported to increase cell survival in response to a wide range of cellular challenges. However, the role of HSP70 overexpression is still a matter of debate, with...

Understanding and optimizing the amplitude modulated control for multiple-slice continuous arterial spin labeling (2005)

Utting,
J.F.,
Thomas,
D.L.,
Gadian,
D.G.,
...

Arterial distensibility in adolescents: the influence of adiposity, the metabolic syndrome, and classic risk factors (2005)

Whincup,
P.H.,
Gilg,
J.A.,
Donald,
A.E.,
...

BACKGROUND: Atherosclerosis develops from childhood, but the determinants of this preclinical stage remain uncertain. We examined the relations of classic coronary risk factors, adiposity and its...

FOXP2 and the neuroanatomy of speech and language (2005)

Vargha-Khadem,
F.,
Gadian,
D.G.,
Copp,
A.,
...

That speech and language are innate capacities of the human brain has long been widely accepted, but only recently has an entry point into the genetic basis of these remarkable faculties been found....

Localization of a type 1 diabetes locus in the IL2RA/CD25 region by use of tag single-nucleotide polymorphisms (2005)

Vella,
A.,
Cooper,
J.D.,
Lowe,
C.E.,
...

As part of an ongoing search for genes associated with type 1 diabetes (T1D), a common autoimmune disease, we tested the biological candidate gene IL2RA (CD25), which encodes a subunit (IL-2R alpha)...

Regional variation of cerebral blood flow and arterial transit time in the normal and hypoperfused rat brain measured using continuous arterial spin labeling MRI (2005)

Thomas,
D.L.,
Lythgoe,
M.F.,
Van Der,
Weerd L.,
...

Continuous arterial spin labeling (CASL) is a noninvasive magnetic resonance (MR) method for measuring cerebral perfusion. In its most widely used form, CASL incorporates a postlabeling delay to...

The role of the medial temporal lobe in autistic spectrum disorders (2005)

Salmond,
C.H.,
Ashburner,
J.,
Connelly,
A.,
...

The neural basis of autistic spectrum disorders (ASDs) is poorly understood. Studies of mnemonic function in ASD suggest a profile of impaired episodic memory with relative preservation of semantic...

Gradual changes in the apparent diffusion coefficient of water in selectively vulnerable brain regions following brief ischemia in the gerbil (2005)

Lythgoe,
M.F.,
Thomas,
D.L.,
Pell,
G.S.,
...

Is anoxic depolarisation associated with an ADC threshold? A Markov chain Monte Carlo analysis (2005)

King,
M.D.,
Crowder,
M.J.,
Hand,
D.J.,
...

A Bayesian nonlinear hierarchical random coefficients model was used in a reanalysis of a previously published longitudinal study of the extracellular direct current (DC)-potential and apparent...

Continuous MLL-ENL Expression Is Necessary to Establish a "Hox Code" and Maintain Immortalization of Hematopoietic Progenitor Cells (2005)

Horton,
S.J.,
Grier,
D.G.,
McGonigle,
G.J.,
...

The t[(11;19)(p22;q23)] translocation, which gives rise to the MLL-ENL fusion protein, is commonly found in infant acute leukemias of both the myeloid and lymphoid lineage. To investigate the...

RP418 (2005)

Gadian,
D.G.

Extra-hippocampal grey matter density abnormalities in paediatric mesial temporal epilepsy (2005)

Cormack,
F.K.,
Gadian,
D.G.,
Vargha-Khadem,
F.,
...

Extra-hippocampal grey matter density abnormalities in paediatric mesial temporal sclerosis (2005)

Cormack,
F.,
Gadian,
D.G.,
Vargha-Khadem,
F.,
...

The aim of this study was to identify grey matter density abnormalities in children with temporal lobe epilepsy and mesial temporal sclerosis. Magnetic resonance T1 weighted 3D datasets were obtained...

Longitudinal MRI measurements of T-2 and CBF in the lithium-pilocarpine model of status epilepticus (2005)

Choy,
M.,
Lythgoe,
M.F.,
Thomas,
D.L.,
...

The effect of deletion 22q11 on brain anatomy and behaviour: A structural imaging study of children with velo-cardio-facial syndrome (VCFS) (2005)

Campbell,
L.E.,
Stevens,
A.,
Daly,
E.,
...

Fatal congenital heart glycogenosis caused by a recurrent activating R531Q mutation in the gamma 2-subunit of AMP- activated protein kinase (PRKAG2), not by phosphorylase kinase deficiency (2005)

Burwinkel,
B.,
Scott,
J.W.,
Buhrer,
C.,
...

Fatal congenital nonlysosomal cardiac glycogenosis has been attributed to a subtype of phosphorylase kinase deficiency, but the underlying genes and mutations have not been identified. Analyzing four...

CYP2A6, MAOA, DBH, DRD4, and 5HT2A genotypes, smoking behaviour and cotinine levels in 1518 UK adolescents (2005)

Huang,
S.,
Cook,
D.G.,
Hinks,
L.J.,
...

Regulatory interdependence of cloned epithelial Na+ channels and P2X receptors. (2005)

Wildman,
S.S.,
Marks,
J.,
Churchill,
L.J.,
...

The phylogenetic position of the 'giant deer' Megaloceros giganteus (2005)

Lister,
A.M.,
Edwards,
C.J.,
Nock,
D.A.W.,
...

Effect of desensitizing agents on the hydraulic conductance of human dentin subjected to different surface pre-treatments - an in vitro study (2005)

Pereira,
J.C.,
Segala,
A.D.,
Gillam,
D.G.

In vitro quantification of changes in human dentine tubule parameters using SEM and digital analysis (2005)

Ahmed,
T.R.,
Mordan,
N.J.,
Gilthorpe,
M.S.,
...

Mutations in the gene LRRK2 encoding dardarin (PARK8) cause familial Parkinson's disease: clinical, pathological, olfactory and functional imaging and genetic data (2005)

Khan,
N.L.,
Jain,
S.,
Lynch,
J.M.,
...

Association of raised titres of antibodies to Chlamydia pneumoniae with a history of pre-eclampsia. (2005)

Goulis,
D.G.,
Chappell,
L.,
Gibbs,
R.G.J.,
...

Extracellular nucleotides and renal function (2005)

Bailey,
M.A.,
Shirley,
D.G.,
King,
B.F.,
...

Extra-hippocampal grey matter density abnormalities in children with temporal lobe epilepsy and mesial temporal sclerosis. (2005)

Cormack,
F.,
Gadian,
D.G.,
Vargha-Khadem,
F.,
...

The fragile X tremor ataxia syndrome in the differential diagnosis of multiple system atrophy: data from the EMSA Study Group (2005)

Kamm,
C.,
Healy,
D.G.,
Quinn,
N.P.,
...

Regional metabolite ratios in two syndromic variants of fronto-temporal dementia using H-1 magnetic resonance spectroscopy. (2004)

Garrard,
P.,
MacManus,
D.G.,
Waldman,
A.D.

Passive smoking and risk of coronary heart disease and stroke: prospective study with cotinine measurement (2004)

Whincup,
P.H.,
Gilg,
J.A.,
Emberson,
J.R.,
...

Developmental regulation of codeine analgesia in the rat (2004)

Williams,
D.G.,
Dickenson,
A.H.,
Fitzgerald,
M.,
...

Microbial keratitis in ITU staff: an occupational hazard? (2004)

Ezra,
D.G.,
Goyal,
S.,
Moosavi,
R.,
...

Microbial keratitis is a potentially blinding corneal infection; the infection may progress rapidly if untreated and result in corneal perforation. The breakdown of the innate ocular defences is...

A preliminary investigation into the ultrastructure of dental calculus and associated bacteria (2004)

Tan,
B.,
Gillam,
D.G.,
Mordan,
N.J.,
...

Clinical evaluation of ferric oxalate in relieving dentine hypersensitivity (2004)

Gillam,
D.G.,
Newman,
H.N.,
Davies,
E.H.,
...

Design-a-trial: a rule-based decision support system for clinical trial design (2004)

Nammuni,
K.,
Pickering,
C.,
Modgil,
S.,
...

Nursing staff and oral care awareness (2004)

Gillam,
J.L.,
Williams,
A.,
Gillam,
D.G.

4036

Language reorganization in children with early onset lesions of the left hemisphere: an fMRI study (2004)

Liégeois,
F.,
Connelly,
A.,
Cross,
J.H.,
...

The expression of DJ-1 (PARK7) in normal human CNS and idiopathic Parkinson's disease. (2004)

Bandopadhyay,
R.,
Kingsbury,
A.E.,
Cookson,
M.R.,
...

2004: 8.201

Potential regulation of Na+ reabsorption in Na+-restricted rats by an ATP-gated P2X4/6 receptor:pharmacological evidence. (2004)

Wildman,
S.S.,
Shirley,
D.G.,
King,
B.F.,
...

Indirect evidence for regulation of sodium reabsorption in sodium-restricted rats by an ATP-gated heteromeric P2X receptor. (2004)

Wildman,
S.S.,
Shirley,
D.G.,
King,
B.F.,
...

Impaired olfactory identification in Asperger Syndrome. (2003)

Suzuki,
Y.,
Critchley,
H.D.,
Rowe,
A.,
...

Developmental amnesia and its relationship to degree of hippocampal atrophy (2003)

Isaacs,
E.B.,
Vargha-Khadem,
F.,
Watkins,
K.E.,
...

Two groups of adolescents, one born preterm and one with a diagnosis of developmental amnesia, were compared with age-matched normal controls on measures of hippocampal volume and memory function....

Language fMRI abnormalities associated with FOXP2 gene mutation (2003)

Liegeois,
F.,
Baldeweg,
T.,
Connelly,
A.,
...

Half the members of the KE family suffer from a speech and language disorder caused by a mutation in the FOXP2 gene. We examined functional brain abnormalities associated with this mutation using two...

Design-a-Trial: a rule-based decision support system for clinical trial design (2003)

Nammuni,
K.,
Pickering,
C.,
Modgil,
S.,
...

15-17 Dec. 2003

Comparative study of the FAIR technique of perfusion quantification with the hydrogen clearance method (2003)

Pell,
G.S.,
King,
M.D.,
Proctor,
E.,
...

Developmental amnesia: Effect of age at injury (2003)

Vargha-Khadem,
F.,
Salmond,
C.H.,
Watkins,
K.E.,
...

European code against cancer and scientific justification: third version (2003) (2003)

Boyle,
P.,
Autier,
P.,
Bartelink,
H.,
...

Oral health and removable partial denture coverage: a pilot study (2003)

Gillam,
D.G.,
Wilson,
R.F.

185

SEM/ESEM investigation of strontium products on etched dentine (2003)

Mordan,
N.J.,
Gillam,
D.G.,
Bock,
N.J.,
...

152

Charts of fetal size: kidney and renal pelvis measurements (2003)

Chitty,
L.S.,
Altman,
D.G.

Bilateral brain abnormalities associated with dominantly inherited verbal and orofacial dyspraxia (2003)

Belton,
E.,
Salmond,
C.H.,
Watkins,
K.E.,
...

The KE family is a large three-generational pedigree in which half of the members suffer from a verbal and orofacial dyspraxia in association with a point mutation in the FOXP2 gene. This report...

Investigating individual differences in brain abnormalities in autism (2003)

Salmond,
C.H.,
De Haan,
M.,
Friston,
K.J.,
...

A direct test for lateralization of language activation using fMRI: Comparison with invasive assessments in children with epilepsy (2003)

Liegeois,
F.,
Connelly,
A.,
Salmond,
C.H.,
...

VEGF: a modifier of the del22q11 (DiGeorge) syndrome? (2003)

Stalmans,
I.,
Lambrechts,
D.,
De Smet,
F.,
...

Stratigraphic imaging of the Navajo Sandstone using ground-penetrating radar (2003)

Jol,
H.M.,
Bristow,
C.S.,
Smith,
D.G.,
...

Distribution assumptions in voxel-based morphometry (2002)

Salmond,
C.H.,
Ashburner,
J.,
Vargha-Khadem,
F.,
...

Distributional assumptions in voxel-based morphometry (2002)

Salmond,
C.H.,
Ashburner,
J.,
Vargha-Khadem,
F.,
...

MRI analysis of an inherited speech and language disorder: structural brain abnormalities (2002)

Watkins,
K.E.,
Vargha-Khadem,
F.,
Ashburner,
J.,
...

The precision of anatomical normalization in the medial temporal lobe using spatial basis functions (2002)

Salmond,
C.H.,
Ashburner,
J.,
Vargha-Khadem,
F.,
...

Asperger Syndrome - a proton magnetic resonance spectroscopy study of brain. (2002)

Murphy,
D.G.,
Critchley,
H.D.,
Schmitz,
N.,
...

Brain anatomy and sensorimotor gating in Asperger's syndrome. (2002)

McAlonan,
G.M.,
Daly,
E.,
Kumari,
V.,
...

Tritylamino aromatic heterocycles as blockers of Ca2+-activated potassium ion channels underlying neuronal hyperpolarization (2002)

Zunszain,
P.A.,
Shah,
M.M.,
Shah,
I.,
...

Turning a deaf ear to fear: impaired recognition of vocal affect in psychopathic individuals. (2002)

Blair,
R.J.,
Mitchell,
D.G.,
Richell,
R.A.,
...

K+ currents generated by NMDA receptor activation in rat hippocampal pyramidal neurones (2002)

Shah,
M.M.,
Haylett,
D.G.

A direct test for lateralization of language activation using fMRI: comparison with invasive assessments in children with epilepsy (2002)

Liégeois,
F.,
Connelly,
A.,
Salmond,
C.H. ,
...

Charts of fetal size: Limb bones (2002)

Chitty,
L.S.,
Altman,
D.G.

A study of the prevalence and distribution of dentine sensitivity in a population of 17-58-year-old serving personnel on an RAF base in the Midlands (2002)

Clayton,
D.R.,
McCarthy,
D.,
Gillam,
D.G.

Dentine hypersensitivity in subjects recruited for clinical trials: clinical evaluation, prevalence and intra-oral distribution (2002)

Gillam,
D.G.,
Aris,
A.,
Bulman,
J.S.,
...

Dentists' perceptions of dentine hypersensitivity and knowledge of its treatment (2002)

Gillam,
D.G.,
Bulman,
J.S.,
Eijkman,
M.A.J.,
...

Effects of abrasive components on dentine: an SEM study (2002)

Mordan,
N.J.,
Gillam,
D.G.,
Critchell,
J.,
...

3010

ESEM vs. SEM evaluation of desensitising dental products on dentine (2002)

Mordan,
N.J.,
Gillam,
D.G.,
Bock,
N.J.,
...

3001

Hypothesis waiting for proof: unwrapping neonates for transfer (2002)

Hawkes,
D.J.,
Spendley,
D.G.,
Alfaham,
M.

The effects of a novel Bioglassr dentifrice on dentine sensitivity: a scanning electron microscopy investigation (2002)

Gillam,
D.G.,
Tang,
J.Y.,
Mordan,
N.J.,
...

Adiabatic radiofrequency pulse forms in biomedical nuclear magnetic resonance (2002)

Norris,
D. G.

Adiabatic radio frequency (RF) pulses are in widespread use in biomedical magnetic resonance imaging and spectroscopy, The primary advantage of adiabatic pulses is that provided the condition for...

Adiabatic radiofrequency pulse forms in biomedical nuclear magnetic resonance (2002)

Norris,
D. G.

Adiabatic radio frequency (RF) pulses are in widespread use in biomedical magnetic resonance imaging and spectroscopy, The primary advantage of adiabatic pulses is that provided the condition for...

Gammaherpesvirus lytic gene expression as characterized by DNA array (2002)

Ahn,
J.W.,
Powell,
K.L.,
Kellam,
P.,
...

Implications of bulk motion for diffusion-weighted imaging experiments: Effects, mechanisms, and solutions (2001)

Norris,
D. G.

The effects of microscopic tissue parameters on the diffusion weighted magnetic resonance imaging experiment (2001)

Norris,
D. G.

Implications of bulk motion for diffusion-weighted imaging experiments: Effects, mechanisms, and solutions (2001)

Norris,
D. G.

The effects of microscopic tissue parameters on the diffusion weighted magnetic resonance imaging experiment (2001)

Norris,
D. G.

A selective impairment in the processing of sad and fearful expressions in children with psychopathic tendencies (2001)

Blair,
R.J.R.,
Colledge,
E.,
Murray,
L.,
...

Monitoring of large randomised clinical trials: a new approach with Bayesian methods (2001)

Parmar,
M.K.,
Griffiths,
G.O.,
Spiegelhalter,
D.J.,
...

Background In judging whether or not to continue enrolling patients into a randomised clinical trial, most data-monitoring and ethics committees (DMECs) rely on the p value for the difference in...

Prolactin response to d-fenfluramine in postmenopausal women on and off ERT: comparison with young women. (2001)

Van Amelsvoort,
T.A.,
Abel,
K.M.,
Robertson,
D.M.,
...

Structural brain abnormalities associated with deletion at chromosome 22q11. Quantitative neuroimaging study of adults with velo-cardio-facial syndrome. (2001)

Van Amelsvoort,
T.,
Daly,
E.,
Robertson,
D.,
...

Clotrimazole analogues: effective blockers of the slow afterhyperpolarization in cultured rat hippocampal pyramidal neurones (2001)

Shah,
M.M.,
Miscony,
Z.,
Javadzadeh-Tabatabaie,
M.,
...

Performance of a new pubertal self-assessment questionnaire: a preliminary study (2001)

Taylor,
S.J.,
Whincup,
P.H.,
Hindmarsh,
P.C.,
...

We describe the performance of a new, self-assessment questionnaire that aims to measure pubertal status by using gender-specific line drawings of the Tanner puberty stages. The study was carried out...

Distal tubular electrolyte transport during inhibition of renal 11β- hydroxysteroid dehydrogenase (2001)

Biller,
K.J.,
Unwin,
R.J.,
Shirley,
D.G.

To test the proposal that the enzyme 11beta-hydroxysteroid dehydrogenase (11beta-HSD) confers aldosterone specificity on mineralocorticoid receptors in the distal nephron by inactivating...

In vivo inhibition of renal 11β-hydroxysteroid dehydrogenase in the rat stimulates collecting duct sodium reabsorption (2001)

Bailey,
M.A.,
Unwin,
R.J.,
Shirley,
D.G.

In order to test the proposal that the aldosterone specificity of mineralocorticoid receptors in the collecting duct depends on inactivation of glucocorticoids by the enzyme 11beta-hydroxysteroid...

Charts of Fetal Size (2001)

Chitty,
L.S.,
Altman,
D.G.

Distal tubular electrolyte transport during inhibition of renal 11beta- hydroxysteroid dehydrogenase (2001)

Biller,
K.J.,
Unwin,
R.J.,
Shirley,
D.G.

To test the proposal that the enzyme 11beta-hydroxysteroid dehydrogenase (11beta-HSD) confers aldosterone specificity on mineralocorticoid receptors in the distal nephron by inactivating...

In vivo inhibition of renal 11 beta-hydroxysteroid dehydrogenase in the rat stimulates collecting duct sodium reabsorption (2001)

Bailey,
M.A.,
Unwin,
R.J.,
Shirley,
D.G.

Reduced power multislice MDEFT imaging (2000)

Norris,
D. G.

Reduced power multislice MDEFT imaging (2000)

Norris,
D. G.

Detecting bilateral abnormalities with voxel-based morphometry (2000)

Salmond,
C.H.,
Ashburner,
J.,
Vargha-Khadem,
F.,
...

Maguire,
E.A.,
Gadian,
D.G.,
Johnsrude,
I.S.,
...

The functional neuroanatomy of social behaviour: Changes in cerebral blood flow when people with autistic disorder process facial expressions. (2000)

Critchley,
H.D.,
Daly,
E.M.,
Bullmore,
E.T.,
...

Prefrontal and medial temporal lobe correlates of repetitive violence to self and others. (2000)

Critchley,
H.D.,
Simmons,
A.,
Daly,
E.M.,
...

Benign central neurocytoma (2000)

Ashkan,
K.,
Casey,
A.T.,
D'Arrigo,
C.,
...

BACKGROUND: "Central neurocytoma" is classically considered as an intraventricular benign tumor, largely based on data from small retrospective series. The authors present prospective data on 12...

The regulation of MR examinations in Germany: a threat to scientific and technical progress for MR in Europe? (2000)