D. G. Evans

Publication List Details

Period

1955 - 2008

Number

121

Co-Authors

Common breast cancer-predisposition alleles are associated with breast cancer risk in BRCA1 and BRCA2 mutation carriers (2008)

Antoniou, A.C., Spurdle, A.B., Sinilnikova, O.M., Healey, S., Pooley, K.A., Schmutzler, R.K., ...

Germline mutations in BRCA1 and BRCA2 confer high risks of breast cancer. However, evidence suggests that these risks are modified by other genetic or environmental factors that cluster in families....

A survey of the Use of Assistive Technology by Students with Dyslexia in Post-Secondary Education (2007)

Draffan, E.A., Evans, D.G., Blenkhorn, P.

Purpose. To identify the types and mix of technology (hardware and software) provided to post-secondary students with dyslexia under the UK's Disabled Student Allowance (DSA), and to determine the...

A survey of the Use of Assistive Technology by Students with Dyslexia in Post-Secondary Education (2007)

Draffan, E.A., Evans, D.G., Blenkhorn, P.

Purpose. To identify the types and mix of technology (hardware and software) provided to post-secondary students with dyslexia under the UK's Disabled Student Allowance (DSA), and to determine the...

A survey of the Use of Assistive Technology by Students with Dyslexia in Post-Secondary Education (2007)

Draffan, E.A., Evans, D.G., Blenkhorn, P.

Purpose. To identify the types and mix of technology (hardware and software) provided to post-secondary students with dyslexia under the UK's Disabled Student Allowance (DSA), and to determine the...

A survey of the Use of Assistive Technology by Students with Dyslexia in Post-Secondary Education (2007)

Draffan, E.A., Evans, D.G., Blenkhorn, P.

Purpose. To identify the types and mix of technology (hardware and software) provided to post-secondary students with dyslexia under the UK's Disabled Student Allowance (DSA), and to determine the...

Innovative Practices in AT Training for LD (Dyslexic) Students (2007)

Draffan, E.A., Evans, D.G., Blenkhorn, P.

Between September and December 2005, we conducted a telephone survey of 455 dyslexic students who had received support under the DSA to identify the equipment supplied, the students’ experiences of...

Innovative Practices in AT Training for LD (Dyslexic) Students (2007)

Draffan, E.A., Evans, D.G., Blenkhorn, P.

Between September and December 2005, we conducted a telephone survey of 455 dyslexic students who had received support under the DSA to identify the equipment supplied, the students’ experiences of...

Innovative Practices in AT Training for LD (Dyslexic) Students (2007)

Draffan, E.A., Evans, D.G., Blenkhorn, P.

Between September and December 2005, we conducted a telephone survey of 455 dyslexic students who had received support under the DSA to identify the equipment supplied, the students’ experiences of...

Innovative Practices in AT Training for LD (Dyslexic) Students (2007)

Draffan, E.A., Evans, D.G., Blenkhorn, P.

Between September and December 2005, we conducted a telephone survey of 455 dyslexic students who had received support under the DSA to identify the equipment supplied, the students’ experiences of...

An absence of cutaneous neurofibromas associated with a 3-bp inframe deletion in exon 17 of the NF1 gene (c.2970-2972 delAAT): evidence of a clinically significant NF1 genotype-phenotype correlation (2007)

Upadhyaya, M., Huson, S.M., Davies, M., Thomas, N., Chuzhanova, N., Giovannini, S., ...

Neurofibromatosis type 1 (NF1) is characterized by cafe-au-lait spots, skinfold freckling, and cutaneous neurofibromas. No obvious relationships between small mutations (ACG change of codon 990....

Do Text-to-Speech Synthesisers Pronounce Correctly? A Preliminary Study (2006)

Evans, D.G., Draffan, E.A., James, A., Blenkhorn, P.

This paper evaluates 4 commercial text-to-speech synthesisers used by dyslexic people to listen to and proof read text. Two evaluators listened to 704 common English words and determined whether the...

Do Text-to-Speech Synthesisers Pronounce Correctly? A Preliminary Study (2006)

Evans, D.G., Draffan, E.A., James, A., Blenkhorn, P.

This paper evaluates 4 commercial text-to-speech synthesisers used by dyslexic people to listen to and proof read text. Two evaluators listened to 704 common English words and determined whether the...

Do Text-to-Speech Synthesisers Pronounce Correctly? A Preliminary Study (2006)

Evans, D.G., Draffan, E.A., James, A., Blenkhorn, P.

This paper evaluates 4 commercial text-to-speech synthesisers used by dyslexic people to listen to and proof read text. Two evaluators listened to 704 common English words and determined whether the...

Do Text-to-Speech Synthesisers Pronounce Correctly? A Preliminary Study (2006)

Evans, D.G., Draffan, E.A., James, A., Blenkhorn, P.

This paper evaluates 4 commercial text-to-speech synthesisers used by dyslexic people to listen to and proof read text. Two evaluators listened to 704 common English words and determined whether the...

Cost-effectiveness of screening with contrast enhanced magnetic resonance imaging vs X-ray mammography of women at a high familial risk of breast cancer (2006)

Griebsch, I., Brown, J., Boggis, C., Dixon, A., Dixon, M., Easton, D., ...

Contrast enhanced magnetic resonance imaging (CE MRI) is the most sensitive tool for screening women who are at high familial risk of breast cancer. Our aim in this study was to assess the...

Evaluation of RAD50 in familial breast cancer predisposition (2005)

Tommiska, J., Seal, S., Renwick, A., Barfoot, R., Baskcomb, L., Jayatilake, H., ...

The genes predisposing to familial breast cancer are largely unknown, but 5 of the 6 known genes are involved in DNA damage repair. RAD50 is part of a highly conserved complex important in...

Screening with magnetic resonance imaging and mammography of a UK population at high familial risk of breast cancer: a prospective multicentre cohort study (MARIBS) (2005)

Leach, M. O., Boggis, C. R., Dixon, A. K., Easton, D. F., Eeles, R. A., Evans, D. G., ...

Background: Women genetically predisposed to breast cancer often develop the disease at a young age when dense breast tissue reduces the sensitivity of X-ray mammography. Our aim was, therefore, to...

Breast and ovarian cancer risks to carriers of the BRCA1 5382insC and 185delAG and BRCA2 6174delT mutations: a combined analysis of 22 population based studies (2005)

Antoniou, A.C., Pharoah, P.D., Narod, S., Risch, H.A., Eyfjord, J.E., Hopper, J.L., ...

A recent report estimated the breast cancer risks in carriers of the three Ashkenazi founder mutations to be higher than previously published estimates derived from population based studies. In an...

Screening with magnetic resonance imaging and mammography of a UK population at high familial risk of breast cancer: A prospective multicentre cohort study (MARIBS) (2005)

Leach, M.O., Boggis, C.R., Dixon, A.K., Easton, D.F., Eeles, R.A., Evans, D.G., ...

Background Women genetically predisposed to breast cancer often develop the disease at a young age when dense breast tissue reduces the sensitivity of X-ray mammography. Our aim was, therefore, to...

Non-uptake of predictive genetic testing for BRCA1/2 among relatives of known carriers: attributes, cancer worry, and barriers to testing in a multicenter clinical cohort (2004)

Foster, C., Evans, D. G., Eeles, R., Eccles, D., Ashley, S., Brooks, L., ...

BRCA1/2 test decliners/deferrers have received almost no attention in the literature and this is the first study of this population in the United Kingdom. The aim of this multicenter study is to...

Average risks of breast and ovarian cancer associated with BRCA1 or BRCA2 mutations detected in case series unselected for family history: a combined analysis of 22 studies (2003)

Antoniou, A., Pharoah, P.D.P., Narod, S., Risch, H.A., Eyfjord, J.E., Hopper, J.L., ...

Germline mutations in BRCA1 and BRCA2 confer high risks of breast and ovarian cancer, but the average magnitude of these risks is uncertain and may depend on the context. Estimates based on...

Variants in CHEK2 other than 1100delC do not make a major contribution to breast cancer susceptibility (2003)

Schutte, M., Meijers-Heijboer, H., Easton, D.F., Wasielewski, M., Evans, D.G., Eccles, D., ...

We recently reported that a sequence variant in the cell-cycle-checkpoint kinase CHEK2 (CHEK2 1100delC) is a low-penetrance breast cancer-susceptibility allele in noncarriers of BRCA1 or BRCA2...

The UK national study of magnetic resonance imaging as a method of screening for breast cancer (MARIBS) (2002)

Leach, M.O., Eeles, R.A., Turnbull, L.W., Dixon, A.K., Brown, J., Hoff, R.J., ...

The UK national study of magnetic resonance imaging as a method of screening for breast cancer (MARIBS) is in progress. The study design, accrual to date, and related research projects are described....

Low-penetrance susceptibility to breast cancer due to CHEK2(*)1100delC in noncarriers of BRCA1 or BRCA2 mutations (2002)

Meijers-Heijboer H, Klijn J, Wasielewski M, De Snoo A, Oldenburg R, ...

Mutations in BRCA1 and BRCA2 confer a high risk of breast and ovarian cancer, but account for only a small fraction of breast cancer susceptibility. To find additional genes conferring susceptibility...

Towards the utilization of Victorian brown coal (1986)

Evans, D. G. (David G.)

Spine title: Utilization of Victorian brown coal. Collected papers. Includes bibliographical references.

The gasification of Victorian brown coal by the Lurgi process (1955)

Evans, D. G. (David G.)

Typescript (carbon copy). Includes bibliographical references (leaves 190-194).

Characterization of a Helicobacter pylori neutrophil-activating protein.

Evans, D J, Evans, D G, Takemura, T, Nakano, H, Lampert, H C, Graham, D Y, ...

Helicobacter pylori-associated gastritis is mainly an inflammatory cell response. In earlier work we showed that activation of human neutrophils by a cell-free water extract of H. pylori is...

Cloning, nucleotide sequence, and expression of a gene encoding an adhesin subunit protein of Helicobacter pylori.

Evans, D G, Karjalainen, T K, Evans, D J, Graham, D Y, Lee, C H

Gene hpaA, which codes for the receptor-binding subunit of the N-acetylneuraminyllactose-binding fibrillar hemagglutinin (NLBH) of Helicobacter pylori, was cloned and sequenced. The protein expressed...

CFA/I-ST plasmids: comparison of enterotoxigenic Escherichia coli (ETEC) of serogroups O25, O63, O78, and O128 and mobilization from an R factor-containing epidemic ETEC isolate.

Murray, B E, Evans, D J, Penãranda, M E, Evans, D G

Colonization factor antigen I (CFA/I) plays an important role in the pathogenesis of diarrhea due to enterotoxigenic Escherichia coli. In this study, we examined 11 CFA/I+ enterotoxigenic E. coli...

ST:LT:CFA/II plasmids in enterotoxigenic Escherichia coli belonging to serogroups O6, O8, O80, O85, and O139.

Peñaranda, M E, Evans, D G, Murray, B E, Evans, D J

Colonization factor antigen II-producing enterotoxigenic Escherichia coli serotypes possessed at least one large plasmid. Loss of colonization factor antigen II correlated with either complete or...

Urease-associated heat shock protein of Helicobacter pylori.

Evans, D J, Evans, D G, Engstrand, L, Graham, D Y

Helicobacter pylori urease is an extracellular, cell-bound enzyme with a molecular weight of approximately 600,000 (600K enzyme) comprising six 66K and six 31K subunits. A 62K protein is closely...

N-acetylneuraminyllactose-binding fibrillar hemagglutinin of Campylobacter pylori: a putative colonization factor antigen.

Evans, D G, Evans, D J, Moulds, J J, Graham, D Y

Campylobacter pylori is the causative agent of gastritis and possibly of peptic and duodenal ulcers in adults. Histological observations show C. pylori attached to gastric epithelium as well as in...

Mannose-resistant hemagglutination of human erythrocytes by enterotoxigenic Escherichia coli with colonization factor antigen II.

Evans, D J, Evans, D G, Diaz, S R, Graham, D Y

The human erythrocyte receptor which mediates mannose-resistant hemagglutination by enterotoxigenic Escherichia coli possessing colonization factor antigen II is not universally distributed among...

Detection of enterotoxigenic Escherichia coli colonization factor antigen I in stool specimens by an enzyme-linked immunosorbent assay.

Evans, D G, Evans, D J, Clegg, S

An enzyme-linked immunosorbent assay (ELISA) was employed to detect and quantitate the fimbrial colonization factor antigen (CFA/I) of enterotoxigenic Escherichia coli in stool specimens obtained...

Hemolysin and K antigens in relation to serotype and hemagglutination type of Escherichia coli isolated from extraintestinal infections.

Evans, D J, Evans, D G, Höhne, C, Noble, M A, Haldane, E V, Lior, H, ...

Escherichia coli isolated from cases of bacteremia and from a variety of urinary tract infections were characterized according to serotype (O:H antigenicity), K type (possession of K1, K2, K3, K12,...

Inhibition of immune hemolysis: serological assay for the heat-labile enterotoxin of Excherichia coli.

Evans, D J, Evans, D G

Sheep erythrocytes sensitized by incubation with the heat-labile enterotoxin (LT) of Escherichia coli are hemolyzed in the presence of anti-LT antiserum and complement. The Microtiter (Cooke...

Serum antibody responses to the N-acetylneuraminyllactose-binding hemagglutinin of Campylobacter pylori.

Evans, D J, Evans, D G, Smith, K E, Graham, D Y

We recently reported that Campylobacter pylori possesses a surface-associated fibrillar hemagglutinin which has an affinity for N-acetylneuraminyllactose; this hemagglutinin may function as a...

Molecular cloning and nucleotide sequence of the colonization factor antigen I gene of Escherichia coli.

Karjalainen, T K, Evans, D G, So, M, Lee, C H

The colonization factor antigen I (CFA/I) gene has been isolated and sequenced. The amino acid sequence of CFA/I deduced from the nucleotide sequence is composed of 170 amino acids. The first 23...

Receptor-mediated adherence of Campylobacter pylori to mouse Y-1 adrenal cell monolayers.

Evans, D G, Evans, D J, Graham, D Y

An in vitro adherence assay was developed to study the adherence of Campylobacter pylori to mammalian cells. Strains of C. pylori were isolated from individuals with gastritis. These strains...

Detection and characterization of colonization factor of enterotoxigenic Escherichia coli isolated from adults with diarrhea.

Evans, D G, Evans, D J, Tjoa, W S, DuPont, H L

The fimbriate colonization factor antigen (CEA) of Escherichia coli strain H-1047 was isolated and used to prepare anti-CFA antiserum. Enterotoxigenic E. coli (ETEC) isolated from 29 adults with...

Hemagglutination patterns of enterotoxigenic and enteropathogenic Escherichia coli determined with human, bovine, chicken, and guinea pig erythrocytes in the presence and absence of mannose.

Evans, D J, Evans, D G, DuPont, H L

A hemagglutination (HA)-typing system has been developed for the presumptive identification of enterotoxigenic Escherichia coli (ETEC) possessing the colonization factor antigens (CFA) CFA/I or...

Purification and characterization of the CFA/I antigen of enterotoxigenic Escherichia coli.

Evans, D G, Evans, D J, Clegg, S, Pauley, J A

The fimbral colonization factor antigen CFA/I of enterotoxigenic Escherichia coli was purified and characterized. The initial purification step was release of these fimbriae from the bacterial cells...

Plasmid-controlled colonization factor associated with virulence in Esherichia coli enterotoxigenic for humans.

Evans, D G, Silver, R P, Evans, D J, Chase, D G, Gorbach, S L

An enterotoxin-producing strain of Escherichia coli isolated from a case of cholera-like diarrhea (E. coli strain H-10407) was found to possess a surface-associated colonization factor. Colonization...

Direct serological assay for the heat-labile enterotoxin of Escherichia coli, using passive immune hemolysis.

Evans, D J, Evans, D G

Sheep erythrocytes sensitized with the heat-labile enterotoxin (LT) of Escherichia coli exhibited passive immune hemolysis (PIH) when exposed to specific antitoxin and complement. Thus, PIH serves as...

Patterns of loss of enterotoxigenicity by Escherichia coli isolated from adults with diarrhea: suggestive evidence for an interrelationship with serotype.

Evans, D J, Evans, D G, DuPont, H L, Orskov, F, Orskov, I

Enterotoxigenic Escherichia coli isolates obtained in Mexico from adult subjects with diarrhea and from healthy controls were examined for the production of heat-stable enterotoxin (ST) and...

Differences in serological responses and excretion patterns of volunteers challenged with enterotoxigenic Escherichia coli with and without the colonization factor antigen.

Evans, D G, Satterwhite, T K, Evans, D J, DuPont, H L

Double-blind studies were performed to compare the virulence of enterotoxigenic Escherichia coli with and without the fimbriate colonization factor antigen (CFA), using young healthy adults (mean...

Production of heat-stable, methanol-soluble enterotoxin by Yersinia enterocolitica.

Boyce, J M, Evans, E J, Evans, D G, DuPont, H L

Seven isolates of Yersinia enterocolitica serotype 0:8, recovered during an outbreak of gastrointestinal illness, were examined for enterotoxin production. All seven strains were enterotoxigenic in...

Comparison of agar based media for primary isolation of Helicobacter pylori.

Hachem, C Y, Clarridge, J E, Evans, D G, Graham, D Y

AIMS--To determine the best medium for the primary isolation of Helicobacter pylori. METHODS--Sixty six gastric mucosal biopsy specimens frozen in 1 ml Cysteine Albimi media with 20% glycerol from 22...

Somatic mosaicism: a common cause of classic disease in tumor-prone syndromes? Lessons from type 2 neurofibromatosis.

Evans, D G, Wallace, A J, Wu, C L, Trueman, L, Ramsden, R T, Strachan, T

Blood samples from 125 families with classic type 2 neurofibromatosis with bilateral vestibular schwannomas were analyzed for mutations in the NF2 gene. Causative mutations were identified in 52...

Heritability of cellular radiosensitivity: a marker of low-penetrance predisposition genes in breast cancer?

Roberts, S A, Spreadborough, A R, Bulman, B, Barber, J B, Evans, D G, Scott, D

Many inherited cancer-prone conditions show an elevated sensitivity to the induction of chromosome damage in cells exposed to ionizing radiation, indicative of defects in the processing of DNA...

Tc-99m-HMPAO white blood cell scan for diagnosis of acute appendicitis in patients with equivocal clinical presentation.

Rypins, E B, Evans, D G, Hinrichs, W, Kipper, S L

OBJECTIVE: The authors' goal was to evaluate the accuracy of Technetium 99m-HMPAO-labeled leukocyte imaging for screening patients with atypically presenting appendicitis and to determine how...

Prevention of tetanus in the wounded.

Smith, J W, Laurence, D R, Evans, D G

Recommendations for the prevention of tetanus in the wounded have been revised to incorporate the use of human tetanus immunoglobulin, which is now available in the United Kingdom. Surgical toilet is...

A linkage study in seven breast cancer families.

Teare, M D, Santibáñez-Koref, M F, Wallace, S A, White, G R, Evans, D G, Burnell, L D, ...

Seven breast cancer families are examined for evidence of linkage to a site in the region of 17q12-q21, by using five markers. The families constitute a subset of a larger series of familial breast...

Characterization of a Helicobacter pylori neutrophil-activating protein.

Evans, D J, Evans, D G, Takemura, T, Nakano, H, Lampert, H C, Graham, D Y, ...

Helicobacter pylori-associated gastritis is mainly an inflammatory cell response. In earlier work we showed that activation of human neutrophils by a cell-free water extract of H. pylori is...

Cloning, nucleotide sequence, and expression of a gene encoding an adhesin subunit protein of Helicobacter pylori.

Evans, D G, Karjalainen, T K, Evans, D J, Graham, D Y, Lee, C H

Gene hpaA, which codes for the receptor-binding subunit of the N-acetylneuraminyllactose-binding fibrillar hemagglutinin (NLBH) of Helicobacter pylori, was cloned and sequenced. The protein expressed...

CFA/I-ST plasmids: comparison of enterotoxigenic Escherichia coli (ETEC) of serogroups O25, O63, O78, and O128 and mobilization from an R factor-containing epidemic ETEC isolate.

Murray, B E, Evans, D J, Penãranda, M E, Evans, D G

Colonization factor antigen I (CFA/I) plays an important role in the pathogenesis of diarrhea due to enterotoxigenic Escherichia coli. In this study, we examined 11 CFA/I+ enterotoxigenic E. coli...

ST:LT:CFA/II plasmids in enterotoxigenic Escherichia coli belonging to serogroups O6, O8, O80, O85, and O139.

Peñaranda, M E, Evans, D G, Murray, B E, Evans, D J

Colonization factor antigen II-producing enterotoxigenic Escherichia coli serotypes possessed at least one large plasmid. Loss of colonization factor antigen II correlated with either complete or...

Urease-associated heat shock protein of Helicobacter pylori.

Evans, D J, Evans, D G, Engstrand, L, Graham, D Y

Helicobacter pylori urease is an extracellular, cell-bound enzyme with a molecular weight of approximately 600,000 (600K enzyme) comprising six 66K and six 31K subunits. A 62K protein is closely...

N-acetylneuraminyllactose-binding fibrillar hemagglutinin of Campylobacter pylori: a putative colonization factor antigen.

Evans, D G, Evans, D J, Moulds, J J, Graham, D Y

Campylobacter pylori is the causative agent of gastritis and possibly of peptic and duodenal ulcers in adults. Histological observations show C. pylori attached to gastric epithelium as well as in...

Mannose-resistant hemagglutination of human erythrocytes by enterotoxigenic Escherichia coli with colonization factor antigen II.

Evans, D J, Evans, D G, Diaz, S R, Graham, D Y

The human erythrocyte receptor which mediates mannose-resistant hemagglutination by enterotoxigenic Escherichia coli possessing colonization factor antigen II is not universally distributed among...

Detection of enterotoxigenic Escherichia coli colonization factor antigen I in stool specimens by an enzyme-linked immunosorbent assay.

Evans, D G, Evans, D J, Clegg, S

An enzyme-linked immunosorbent assay (ELISA) was employed to detect and quantitate the fimbrial colonization factor antigen (CFA/I) of enterotoxigenic Escherichia coli in stool specimens obtained...

Hemolysin and K antigens in relation to serotype and hemagglutination type of Escherichia coli isolated from extraintestinal infections.

Evans, D J, Evans, D G, Höhne, C, Noble, M A, Haldane, E V, Lior, H, ...

Escherichia coli isolated from cases of bacteremia and from a variety of urinary tract infections were characterized according to serotype (O:H antigenicity), K type (possession of K1, K2, K3, K12,...

Inhibition of immune hemolysis: serological assay for the heat-labile enterotoxin of Excherichia coli.

Evans, D J, Evans, D G

Sheep erythrocytes sensitized by incubation with the heat-labile enterotoxin (LT) of Escherichia coli are hemolyzed in the presence of anti-LT antiserum and complement. The Microtiter (Cooke...