D. J.

Self-Calibrating 3D-Ultrasound-Based Bone Registration for Minimally Invasive Orthopedic Surgery (2006)

Intraoperative freehand three-dimensional (3-D) ultrasound (3D-US) has been proposed as a noninvasive method for registering bones to a preoperative computed tomography image or computer-generated...

Compartmentalized and signal-selective gap junctional coupling in the hearing cochlea (2006)

  • Jagger,
  • D.J.,
  • Forge,
  • A.

Gap junctional intercellular communication (GJIC) plays a major role in cochlear function. Recent evidence suggests that connexin 26 (Cx26) and Cx30 are the major constituent proteins of cochlear gap...

Ultrasound-based registration for minimally-invasive orthopaedic surgery (2006)

  • Barratt,
  • D.C.,
  • Penney,
  • G.P.,
  • Slomczykowski,
  • M.,
  • ...

The use of medical images to guide the surgeon plays a critical role in enabling minimally-invasive orthopaedic procedures to be performed safely and effectively. A fundamental task during such...

Cadaver Validation of intensity-based ultrasound to CT registration (2006)

A method is presented for the rigid registration of tracked B-mode ultrasound images to a CT volume of a femur and pelvis. This registration can allow tracked surgical instruments to be aligned with...

The effects of unfractionated heparin, low molecular weight heparin and danaparoid on the thromboelastogram (TEG): an in-vitro comparison of standard and heparinase-modified TEGs with conventional coagulation assays (2006)

  • Coppell,
  • J.A.,
  • Thalheimer,
  • U.,
  • Zambruni,
  • A.,
  • ...

To investigate the effects of unfractionated heparin (UFH), low molecular weight heparin (LMWH) and danaparoid (DPD) added to whole blood in vitro on standard and heparinase-modified...

Increased endogenous angiogenic response and hypoxia-inducible factor-1 alpha in human critical limb ischemia (2006)

  • Ho,
  • T.K.,
  • Rajkumar,
  • V.,
  • Ponticos,
  • M.,
  • ...

Objective: The potent physiologic endogenous angiogenic response to ischemic stimuli is often suboptimal, and therefore, a better understanding of the basic mechanisms is essential for the use in...

The Evolution of the Car Burglar (2006)

  • Donkin,
  • S.,
  • Wellsmith,
  • M.,
  • Birks,
  • D.J.

Mass balance of the Antarctic ice sheet (2006)

  • Wingham,
  • D.J,
  • Shepherd,
  • A.,
  • Muir,
  • A.,
  • ...

Programa de Voluntariado na Empresa: uma Abordagem Comunicacional (2005)

Trabalho apresentado no NP 05 - Relações Públicas e Comunicação Organizacional no XXVII Congresso Brasileiro de Ciências da Comunicação, Porto...

Voluntariado e Comunicação na Empresa: Para Além da Inclusividade Controlada (2005)

Trabalho apresentado no NP05 - Relações Publicas e Comunicação Organizacional durante o XXVIII Congresso Brasileiro de Ciências da Comunicação, Rio de...

Jornais,pierrots e flores...Selavy (2005)

  • TRINDADE,
  • D.J

Trabalho apresentado no NP15 - Semiótica da Comunicação durante o XXVIII Congresso Brasileiro de Ciências da Comunicação, Rio de Janeiro, RJ,...

Estratégias discursivas na construção do ataque de 11/9/2001 (2005)

Trabalho apresentado no NP15 - Semiótica da Comunicação durante o XXVIII Congresso Brasileiro de Ciências da Comunicação, Rio de Janeiro, RJ,...

CHLORIDE POISONING OF WATER GAS SHIFT ACTIVITY ON NICKEL CATALYSTS DURING STEAM REFORMING. (R822721C633) (2005)

The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the...

Cognitive processes in saccade generation (2005)

  • Kennard,
  • C.,
  • Mannan,
  • P.,
  • Nachev,
  • P.,
  • ...

Tissue deformation and shape models in image-guided interventions: a discussion paper (2005)

  • Hawkes,
  • D.J.,
  • Barratt,
  • D.,
  • Blackall,
  • J.M.,
  • ...

This paper promotes the concept of active models in image-guided interventions. We outline the limitations of the rigid body assumption in image-guided interventions and describe how intraoperative...

Application of soft tissue modelling to image-guided surgery (2005)

  • Carter,
  • T.J.,
  • Sermesant,
  • M.,
  • Cash,
  • D.M.,
  • ...

The deformation of soft tissue compromises the accuracy of image-guided surgery based on preoperative images, and restricts its applicability to surgery on or near bony structures. One way to...

Cadaver validation of intensity-based ultrasound-to-CT registration (2005)

A method is presented for the registration of tracked B-mode ultrasound images to a CT volume of a femur or pelvis. This registration can allow tracked surgical instruments to be aligned with the CT...

Self-calibrating ultrasound-to-CT bone registration (2005)

We describe a new self-calibrating approach to rigid registration of 3D ultrasound images in which in vivo data acquired for registration are used to simultaneously perform a patient-specific update...

Generation of functional ion-channel tools by E3 targeting (2005)

  • Xu,
  • S.Z.,
  • Zeng,
  • F.,
  • Lei,
  • M.,
  • ...

Here we describe a strategy for generating ion-channel inhibitors. It takes advantage of antibody specificity combined with a pattern recognition approach that targets the third extracellular region...

Patients with unsolved congenital disorders of glycosylation type II can be subdivided in six distinct biochemical groups (2005)

  • Wopereis,
  • S.,
  • Morava,
  • E.,
  • Grunewald,
  • S.,
  • ...

Defects in the biosynthesis of N- and core 1 O-glycans may be found by isoelectric focusing (IEF) of plasma transferrin and apolipoprotein C-III (apoC-III). We hypothesized that IEF of transferrin...

Mycosis fungoides with a CD56(+) immunophenotype (2005)

  • Wain,
  • E.M.,
  • Orchard,
  • G.E.,
  • Mayou,
  • S.,
  • ...

We report 3 cases of mycosis fungoides (MF) with a CD56(+) cytotoxic immunophenotype. Each patient presented with a different clinical phenotype: one exhibited limited poikilodermatous patches (skin...

Disruption of Bardet-Biedl syndrome ciliary proteins perturbs planar cell polarity in vertebrates (2005)

  • Ross,
  • A.J.,
  • May-Simera,
  • H.,
  • Eichers,
  • E.R.,
  • ...

The evolutionarily conserved planar cell polarity (PCP) pathway (or noncanonical Wnt pathway) drives several important cellular processes, including epithelial cell polarization, cell migration and...

Genetic heterogeneity in Rubinstein-Taybi syndrome: mutations in both the CBP and EP300 genes cause disease (2005)

  • Roelfsema,
  • J.H.,
  • White,
  • S.J.,
  • Ariyurek,
  • Y.,
  • ...

CREB-binding protein and p300 function as transcriptional coactivators in the regulation of gene expression through various signal-transduction pathways. Both are potent histone acetyl transferases....

The pediatric rheumatology international trials organization criteria for the evaluation of response to therapy in juvenile systemic lupus erythematosus - Prospective validation of the disease activity core set (2005)

  • Ruperto,
  • N.,
  • Ravelli,
  • A.,
  • Cuttica,
  • R.,
  • ...

Objective. To validate and promulgate a core set of outcome measures for the evaluation of response to treatment in patients with juvenile systemic lupus erythematosus (SLE). Methods. In 2001, a...

Vangl2 acts via RhoA signaling to regulate polarized cell movements during development of the proximal outflow tract (2005)

  • Phillips,
  • H.M.,
  • Murdoch,
  • J.N.,
  • Chaudhry,
  • B.,
  • ...

Loop-tail (Lp) mice develop double outlet right ventricle and aortic arch defects, and the defects are caused by mutations in the Vangl2 gene. Vangl2 mRNA is found in the outflow tract myocardium,...

Solid-pseudopapillary neoplasm of the pancreas: radiological-pathological correlation (2005)

  • Moholkar,
  • S.,
  • Sebire,
  • N.J.,
  • Roebuck,
  • D.J.

We report two cases to demonstrate the imaging features of solid-pseudopapillary neoplasm of the pancreas (SPNP) in children. The SPNP is heterogeneous and often shows evidence of a pseudocapsule and...

Expression of the Brn-3b Transcription Factor Correlates with Expression of HSP-27 in Breast Cancer Biopsies and Is Required for Maximal Activation of the HSP-27 Promoter (2005)

  • Lee,
  • S.A.,
  • Ndisang,
  • D.,
  • Patel,
  • C.,
  • ...

In breast cancer, overexpression of the small heat shock protein, HSP-27, is associated with increased anchorage-independent growth, increased invasiveness, and resistance to chemotherapeutic drugs...

Large meta-analysis establishes the ACE insertion-deletion polymorphism as a marker of Alzheimer's disease (2005)

  • Lehmann,
  • D.J.,
  • Cortina-Borja,
  • M.,
  • Warden,
  • D.R.,
  • ...

Apolipoprotein E epsilon 4 (APOE*4) is the only fully established susceptibility allele for Alzheimer's disease. One of the most studied candidates is the insertion (I)/deletion (D) polymorphism...

Is anoxic depolarisation associated with an ADC threshold? A Markov chain Monte Carlo analysis (2005)

A Bayesian nonlinear hierarchical random coefficients model was used in a reanalysis of a previously published longitudinal study of the extracellular direct current (DC)-potential and apparent...

Molecular and clinical analyses of Greig cephalopolysyndactyly and Pallister-Hall syndromes: robust phenotype prediction from the type and position of GLI3 mutations (2005)

  • Johnston,
  • J.J.,
  • Olivos-Glander,
  • I.,
  • Killoran,
  • C.,
  • ...

Mutations in the GLI3 zinc-finger transcription factor gene cause Greig cephalopolysyndactyly syndrome (GCPS) and Pallister-Hall syndrome (PHS), which are variable but distinct clinical entities. We...

HIV knowledge and risk behaviour of female sex workers in Yunnan Province, China: potential as bridging groups to the general population (2005)

  • Hesketh,
  • T.,
  • Zhang,
  • J.,
  • Qiang,
  • D.J.

There is growing evidence about the importance of female sex workers (FSWs) and their clients as bridging groups for the HIV epidemic. In China the role of FSWs is key to the future trajectory of the...

Peliosis hepatis causing inferior vena cava compression in a 3- year-old child (2005)

Peliosis hepatis is a rare benign condition characterized by oval or irregular, multiple blood-filled spaces within the liver parenchyma. It is most commonly seen in adults and may be idiopathic, but...

Event-related brain potential correlates of human auditory sensory memory-trace formation (2005)

  • Haenschel,
  • C.,
  • Vernon,
  • D.J.,
  • Dwivedi,
  • P.,
  • ...

The event-related potential (ERP) component mismatch negativity (MMN) is a neural marker of human echoic memory. MMN is elicited by deviant sounds embedded in a stream of frequent standards,...

The effect of prepartum antibiotics on the type of neonatal bacteraemia: insights from the MRC ORACLE trials (2005)

  • Gilbert,
  • R.E.,
  • Pike,
  • K.,
  • Kenyon,
  • S.L.,
  • ...

We analysed the type of bacteraemia before discharge from Neonatal Intensive Care Units in babies born to women randomised to the MRC ORACLE Trials. There was no evidence for an effect of oral...

Zic4, a zinc-finger transcription factor, is expressed in the developing mouse nervous system (2005)

  • Gaston-Massuet,
  • C.,
  • Henderson,
  • D.J.,
  • Greene,
  • N.D.,
  • ...

Zic genes comprise a family of transcription factors, characterized by the presence of a zinc-finger domain containing two cysteines and two histidines (C2-H2). Whereas the embryonic expression...

Brn-3a neuronal transcription factor functional expression in human prostate cancer (2005)

Neuroendocrine differentiation has been associated with prostate cancer (CaP). Brn-3a (short isoform) and Brn-3c, transcriptional controllers of neuronal differentiation, were readily detectable in...

Endothelial function and dysfunction. Part I: methodological issues for assessment in the different vascular beds: a statement by the Working Group on Endothelin and Endothelial Factors of the European Society of Hypertension (2005)

  • Deanfield,
  • J.,
  • Donald,
  • A.,
  • Ferri,
  • C.,
  • ...

An enormous number of studies in the last two decades have been devoted to investigating the role of the endothelium in cardiovascular diseases. Nonetheless, the optimal methodology for investigating...

Endothelial function and dysfunction. Part I: Methodological issues for assessment in the different vascular beds: a statement by the Working Group on Endothelin and Endothelial Factors of the European Society of Hypertension (2005)

  • Deanfield,
  • J.E.,
  • Donald,
  • A.,
  • Ferri,
  • C.,
  • ...

An enormous number of studies in the last two decades have been devoted to investigating the role of the endothelium in cardiovascular diseases. Nonetheless, the optimal methodology for investigating...

Preoperative assessment of secondary intraocular lens implantation for aphakia: a comparison of 2 techniques (2005)

PURPOSE: To compare the preoperative evaluation of secondary intraocular lens (IOL) implantation in aphakic adults following cataract extraction in childhood using slitlamp examination and...

Pulmonary atresia with intact ventricular septum: predictors of early and medium-term outcome in a population-based study (2005)

  • Daubeney,
  • P.E.,
  • Wang,
  • D.,
  • Delany,
  • D.J.,
  • ...

Objectives: Pulmonary atresia with intact ventricular septum is a form of congenital heart disease usually associated with right-heart hypoplasia, with considerable morphologic heterogeneity and...

Endothelial function and dysfunction. Part II: Association with cardiovascular risk factors and diseases. A statement by the Working Group on Endothelins and Endothelial Factors of the European Society of Hypertension (2005)

  • Brunner,
  • H.,
  • Cockcroft,
  • J.R.,
  • Deanfield,
  • J.E.,
  • ...

Dysfunction of the vascular endothelium is a hallmark of most conditions that are associated with atherosclerosis and is therefore held to be an early feature in atherogenesis. However, the...

Thalidomide in the management of epidermolysis bullosa pruriginosa (2005)

  • Bulic,
  • S.O.,
  • Fassihi,
  • H.,
  • Mellerio,
  • J.E.,
  • ...

Epidermolysis bullosa (EB) pruriginosa is a distinctive clinical subtype of dystrophic EB. We report a patient with dominant dystrophic EB pruriginosa, who had an excellent response to systemic...

The prevalence of the cysteine1584 variant of von Willebrand factor is increased in type 1 von Willebrand disease: co- segregation with increased susceptibility to ADAMTS13 proteolysis but not clinical phenotype (2005)

  • Bowen,
  • D.J.,
  • Collins,
  • P.W.,
  • Lester,
  • W.,
  • ...

The molecular pathogenesis of type 1 von Willebrand disease (VWD) is uncertain in most patients. We examined 30 type 1 VWD families in the UK Haemophilia Centre Doctors' Organization study....

A comparison of a similarity-based and a feature-based 2-D-3-D registration method for neurointerventional use (2005)

  • McLaughlin,
  • R.A.,
  • Hipwell,
  • J.,
  • Hawkes,
  • D.J.,
  • ...

Two-dimensional (2-D)-to-three-dimensional (3-D) registration can improve visualization which may aid minimally invasive neurointerventions. Using clinical and phantom studies, two state-of-the-art...

Alignment of sparse freehand 3-D ultrasound with preoperative images of the liver using models of respiratory motion and deformation (2005)

We present a method for alignment of an interventional plan to optically tracked two-dimensional intraoperative ultrasound (US) images of the liver. Our clinical motivation is to enable the accurate...

Anisotropic multi-scale fluid registration: evaluation in magnetic resonance breast imaging (2005)

Registration using models of compressible viscous fluids has not found the general application of some other techniques (e.g. free-form-deformation (FFD)) despite its ability to model large...

Novel approaches to the measurement of arterial blood flow from dynamic digital X-ray images (2005)

  • Rhode,
  • K.S.,
  • Lambrou,
  • T.,
  • Hawkes,
  • D.J.,
  • ...

We have developed two new algorithms for the measurement of blood flow from dynamic X-ray angiographic images. Both algorithms aim to improve on existing techniques. First, a model-based (MB)...

Semen quality before and after gonadotoxic treatment (2005)

  • Bahadur,
  • G.,
  • Ozturk,
  • O.,
  • Muneer,
  • A.,
  • ...

Spectrally opponent inputs to the human luminance pathway: slow +L and -M cone inputs revealed by low to moderate long-wavelength adaptation (2005)

  • Stockman,
  • A.,
  • Plummer,
  • D.J.

The luminance pathway has slow (s), spectrally opponent cone inputs in addition to the expected fast (f), non-opponent inputs. The nature of these inputs to luminance flicker perception was further...

IFN-gamma gene expression is controlled by the architectural transcription factor HMGA1 (2005)

  • Chau,
  • K.Y.,
  • Keane-Myers,
  • A.M.,
  • Fedele,
  • M.,
  • ...

We report for the first time that IFNG gene expression requires high mobility group (HMG)A1, the architectural transcription factor mediating enhanceosome formation. This finding is supported by our...

Mineralogy of Tailings Dump around Selebi Phikwe Nickel-Copper Plant, Botswana (2004)

This study aimed at mineralogically characterizing the tailings dump emanating from the mining and smelting of nickel-copper (Ni-Cu) at Selebi Phikwe, Botswana, Southern Africa. Samples of tailings...

Cadaver validation of the use of ultrasound for the instantiation of bony anatomy in image-guided orthopaedic surgery (2004)

We present cadaver validation of a method that uses tracked ultrasound to instantiate and register 3D statistical shape models (SSMs) of 3 femurs and 2 pelves. The SSMs were generated directly from...

Assessment of a technique for 2D-3D registration of cerebral intra-arterial angiography (2004)

  • Byrne,
  • J.V.,
  • Colominas,
  • C.,
  • Hipwell,
  • J.,
  • ...

This study assesses the ability of a computer algorithm to perform automated 2D-3D registrations of digitally subtracted cerebral angiograms. The technique was tested on clinical studies of five...

The effect of image colour distortion on evaluation of donor liver suitability for transplantation (2004)

Some medical applications rely on the use of colour in the diagnostic process, even when poor colour reproduction can affect diagnosis. In this paper, we investigate the effect colour distortion can...

Performance of octene in fluorous biphasic hydroformylation: octene distribution and reversible transfer between perfluoromethylcyclohexane and nonanal (2004)

  • Huang,
  • Y.L.,
  • Perperi,
  • E.,
  • Manos,
  • G.,
  • ...

During fluorous biphasic hydroformylation 1-octene is transferred from the fluorous into the organic product phase and then from the product layer back to the fluorous layer again, due to the...

The problem of perceiving accurate depth information through a surgical augmented reality system (2003)

27/02/03 to 01/03/03, Interlaken, Switzerland

The anatomy of visual neglect (2003)

  • Mort,
  • D.J.,
  • Malhotra,
  • P.,
  • Mannan,
  • S.K.,
  • ...

Cardiac catheterisation guided by MRI in children and adults with congenital heart disease (2003)

  • Razavi,
  • R.,
  • Hill,
  • D.L.,
  • Keevil,
  • S.F.,
  • ...

BACKGROUND: Fluoroscopically guided cardiac catheterisation is an essential tool for diagnosis and treatment of congenital heart disease. Drawbacks include poor soft tissue visualisation and exposure...

Information theoretic similarity measures in non-rigid registration (2003)

Mutual Information (MI) and Normalised Mutual Information (NMI) have enjoyed success as image similarity measures in medical image registration. More recently, they have been used for non-rigid...

Intensity-based 2-D-3-D registration of cerebral angiograms (2003)

We propose a new method for aligning three-dimensional (3-D) magnetic resonance angiography (MRA) with 2-D X-ray digital subtraction angiograms (DSA). Our method is developed from our algorithm to...

Measurement and analysis of brain deformation during neurosurgery (2003)

  • Hartkens,
  • T.,
  • Hill,
  • D.L.,
  • Castellano-Smith,
  • A.D.,
  • ...

Recent studies have shown that the surface of the brain is deformed by up to 20 mm after the skull is opened during neurosurgery, which could lead to substantial error in commercial image-guided...

Medical Implications of Biofilms (2003)

  • An,
  • Y.H.,
  • Bhagwat,
  • S.,
  • Bokranz,
  • W.,
  • ...

Myocardial delineation via registration in a polar coordinate system (2003)

  • Noble,
  • N.M.,
  • Hill,
  • D.L.,
  • Breeuwer,
  • M.,
  • ...

RATIONALE AND OBJECTIVES: Cardiovascular disease is the number one cause of premature death in the western world. Analysis of cardiac function provides clinically useful diagnostic and prognostic...

Organization of the visual cortex in human albinism (2003)

In albinism there is an abnormal projection of part of the temporal retina to the visual cortex contralateral to the eye. This projection, together with the normally routed fibers from nasal retina,...

Retinal transplantation: progress and problems in clinical application (2003)

There is currently no real treatment for blinding disorders that stem from the degeneration of cells in the retina and affect at least 50 million individuals worldwide. The excitement that...

SMASH navigators (2003)

  • Bydder,
  • M.,
  • Atkinson,
  • D.,
  • Larkman,
  • D.J.,
  • ...

Survival analysis of all-ceramic restorations (2003)

  • Benny-Wilson,
  • G.,
  • McDonald,
  • A.V.,
  • Setchell,
  • D.J.

Zen and the art of medical image registration: correspondence, homology, and quality (2003)

Nonrigid registration (NRR) is routinely used in the study of neuroanatomy and function and is a standard component of analysis packages such as SPM. There remain many unresolved correspondence...

Markers of platelet activation, thrombin generation and fibrinolysis in women with sickle cell disease: effects of differing forms of hormonal contraception (2003)

Objective: To examine laboratory markers of platelet activation, thrombin generation and fibrinolysis in women with sickle cell disease (SCD) using the combined oral contraceptive pill (COCP),...

The MINOS light injection calibration system (2002)

  • Adamson,
  • P.,
  • Anderson,
  • B.,
  • Attree,
  • D.J.,
  • ...

Comparison between radiological and artificial neural network diagnosis in clinical screening (2002)

  • Degenhard,
  • A.,
  • Tanner,
  • C.,
  • Hayes,
  • C.,
  • ...

The imaging protocol of the UK multicentre magnetic resonance imaging study for screening in women at genetic risk of breast cancer aims to assist in detecting and diagnosing malignant breast...

Deforming a preoperative volume to represent the intraoperative scene (2002)

  • Penney,
  • G.P.,
  • Little,
  • J.A.,
  • Weese,
  • J.,
  • ...

Soft-tissue deformation can be a problem if a preoperative modality is used to help guide a surgical or interventional procedure. We present a method that can warp a preoperative CT image to...

Pseudodominant inheritance of Langer mesomelic dysplasia caused by a SHOX homeobox missense mutation (2002)

  • Shears,
  • D.J.,
  • Guillen-Navarro,
  • E.,
  • Sempere-Miralles,
  • M.,
  • ...

We report the clinical and molecular analysis in a consanguineous family in which the skeletal dysplasias Leri-Weill dyschondrosteosis (LWD) and Langer mesomelic dysplasia (LMD) both segregate. A...

Comparison of survival, palliation, and quality of life with three chemotherapy regimens in metastatic colorectal cancer: a multicentre randomised trial (2002)

Background This randomised trial compared three chemotherapy regimens in the first-line treatment of advanced colorectal cancer, in terms of their effect on overall and progression- free survival;...

Monitoring of large randomised clinical trials: a new approach with Bayesian methods (2001)

Background In judging whether or not to continue enrolling patients into a randomised clinical trial, most data-monitoring and ethics committees (DMECs) rely on the p value for the difference in...

The action of isoprenaline on the electrophysiological properties of hypertrophied left ventricular myocytes (2001)

  • Wallis,
  • W.,
  • Cooklin,
  • M.,
  • Sheridan,
  • D.J.,
  • ...

The electrophysiological effects of the beta-agonist, isoprenaline, on hypertrophied left ventricular myocardium were measured to understand better the arrhythmic effects of beta-stimulation on the...

Multiple groups of novel retroviral genomes in pigs and related species (2001)

  • Patience,
  • C.,
  • Switzer,
  • W.M.,
  • Takeuchi,
  • Y.,
  • ...

In view of the concern over potential infection hazards in the use of porcine tissues and organs for xenotransplantation to humans, we investigated the diversity of porcine endogenous retrovirus...

Multiple groups of novel retroviral genomes in pigs and related species (2001)

  • Patience,
  • C.,
  • Switzer,
  • W.M.,
  • Takeuchi,
  • Y.,
  • ...

In view of the concern over potential infection hazards in the use of porcine tissues and organs for xenotransplantation to humans, we investigated the diversity of porcine endogenous retrovirus...

The influence of gender, social circumstances and smoking on survival: the Renfrew and Paisley study (2000)

The present study aimed to compare survival to age 75 between men and women, by social circumstances and smoking behaviour. A 20 year follow up was carried out of a large representative cohort of...

Eye movements and visual forces in the landscape (2000)

  • Aspinall,
  • P.,
  • Hill,
  • A.,
  • Stuart-Murray,
  • J.,
  • ...

Mammalian target of rapamycin is a direct target for protein kinase B: identification of a convergence point for opposing effects of insulin and amino-acid deficiency on protein translation (1999)

  • Nave,
  • B.T.,
  • Ouwens,
  • M.,
  • Withers,
  • D.J.,
  • ...

Growth factor induced activation of phosphoinositide 3-kinase and protein kinase B (PKB) leads to increased activity of the mammalian target of rapamycin (mTOR). This subsequently leads to increased...

 
Additional Information

Publishing period:

1995 - 2006 (265)

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