D. J. DeFriend

Intraluminal stenting in the management of adhesional intestinal obstruction.

DeFriend, D J, Klimack, O E, Humphrey, C S, Schraibman, I G

Intraluminal stenting of the small bowel has been advocated as a method of reducing the risk of recurrent adhesional obstruction in patients requiring adhesolysis. We reviewed the complications and...

Effect of anorectal eversion on long-term clinical outcome of restorative proctocolectomy.

DeFriend, D J, Mughal, M, Grace, R H, Schofield, P F

Eversion of the rectum during restorative proctocolectomy with stapled ileal pouch-anal anastomosis (IPAA) remains a controversial surgical manoeuvre because of concern that it may impair anal...

Intraluminal stenting in the management of adhesional intestinal obstruction.

DeFriend, D J, Klimack, O E, Humphrey, C S, Schraibman, I G

Intraluminal stenting of the small bowel has been advocated as a method of reducing the risk of recurrent adhesional obstruction in patients requiring adhesolysis. We reviewed the complications and...

Effect of anorectal eversion on long-term clinical outcome of restorative proctocolectomy.

DeFriend, D J, Mughal, M, Grace, R H, Schofield, P F

Eversion of the rectum during restorative proctocolectomy with stapled ileal pouch-anal anastomosis (IPAA) remains a controversial surgical manoeuvre because of concern that it may impair anal...

Effects of 4-hydroxytamoxifen and a novel pure antioestrogen (ICI 182780) on the clonogenic growth of human breast cancer cells in vitro.

DeFriend, D. J., Anderson, E., Bell, J., Wilks, D. P., West, C. M., Mansel, R. E., ...

We have investigated the effects on breast cancer cell growth of 4-hydroxytamoxifen (4OHT), a conventional antioestrogen with agonist activity, and 7...

Pharmacokinetics, pharmacological and anti-tumour effects of the specific anti-oestrogen ICI 182780 in women with advanced breast cancer.

Howell, A., DeFriend, D. J., Robertson, J. F., Blamey, R. W., Anderson, L., Anderson, E., ...

We have assessed the pharmacokinetics, pharmacological and anti-tumour effects of the specific steroidal anti-oestrogen ICI 182780 in 19 patients with advanced breast cancer resistant to tamoxifen....