D. J. McCool

The T84 human colonic adenocarcinoma cell line produces mucin in culture and releases it in response to various secretagogues.

McCool, D J, Marcon, M A, Forstner, J F, Forstner, G G

The T84 colonic adenocarcinoma cell line, which has been used extensively as a model for studies of epithelial chloride secretion, also produces mucin and secretes it in culture. Electron microscopy...

Regulated and unregulated pathways for MUC2 mucin secretion in human colonic LS180 adenocarcinoma cells are distinct.

McCool, D J, Forstner, J F, Forstner, G G

We have shown previously [McCool, Forstner and Forstner (1994) Biochem. J. 302, 111-118] using pulse-chase labelling of mucin with [3H]threonine that LS180 colonic tumour cells synthesize and secrete...

Synthesis and secretion of mucin by the human colonic tumour cell line LS180.

McCool, D J, Forstner, J F, Forstner, G G

Pulse-chase labelling experiments were performed using the mucin-producing colonic carcinoma cell line LS180. Cells were pulsed with [3H]threonine or [3H]glucosamine and chased in complete media...

Roles of calreticulin and calnexin during mucin synthesis in LS180 and HT29/A1 human colonic adenocarcinoma cells.

McCool, D J, Okada, Y, Forstner, J F, Forstner, G G

Molecular chaperones are presumed to associate with large secretory mucin glycoproteins during their synthesis in the endoplasmic reticulum (ER), but have not been identified to date. We decided to...

The T84 human colonic adenocarcinoma cell line produces mucin in culture and releases it in response to various secretagogues.

McCool, D J, Marcon, M A, Forstner, J F, Forstner, G G

The T84 colonic adenocarcinoma cell line, which has been used extensively as a model for studies of epithelial chloride secretion, also produces mucin and secretes it in culture. Electron microscopy...

Regulated and unregulated pathways for MUC2 mucin secretion in human colonic LS180 adenocarcinoma cells are distinct.

McCool, D J, Forstner, J F, Forstner, G G

We have shown previously [McCool, Forstner and Forstner (1994) Biochem. J. 302, 111-118] using pulse-chase labelling of mucin with [3H]threonine that LS180 colonic tumour cells synthesize and secrete...

Synthesis and secretion of mucin by the human colonic tumour cell line LS180.

McCool, D J, Forstner, J F, Forstner, G G

Pulse-chase labelling experiments were performed using the mucin-producing colonic carcinoma cell line LS180. Cells were pulsed with [3H]threonine or [3H]glucosamine and chased in complete media...

Roles of calreticulin and calnexin during mucin synthesis in LS180 and HT29/A1 human colonic adenocarcinoma cells.

McCool, D J, Okada, Y, Forstner, J F, Forstner, G G

Molecular chaperones are presumed to associate with large secretory mucin glycoproteins during their synthesis in the endoplasmic reticulum (ER), but have not been identified to date. We decided to...