Nicholls, D. J., Martin, J. W.
Small-fatigue-crack growth data have been compared with long-fatigue- crack data generated in the Al-Li-Cu-Mg-Zr alloy 8090; not unexpectedly, small fatigue cracks were observed to grow significantly...
Nicholls, D. J., Martin, J. W.
A study of small fatigue crack properties in aluminum alloy 8090 was conducted. It was found that the growth rate of small fatigue cracks was proportional to delta K squared. This equation has been...
Alldread, R M, Halsall, D M, Clarke, A R, Sundaram, T K, Atkinson, T, Scawen, M D, ...
The nucleotide-binding fold of many NAD(+)-dependent dehydrogenases contains a conserved acidic amino acid residue which hydrogen-bonds with the 2'- and 3'-hydroxy groups of the adenine-ribose of the...
Moola, Z B, Scawen, M D, Atkinson, T, Nicholls, D J
This study shows that the antigenicity of Erwinia chrysanthemi L-asparaginase can be reduced by site-directed mutagenesis. Ten B-cell epitopes of the enzyme were identified using synthetic...
Nobbs, T J, Cortés, A, Gelpi, J L, Holbrook, J J, Atkinson, T, Scawen, M D, ...
The X-ray structure of lactate dehydrogenase (LDH) shows the side-chain carboxylate group of Asp-143 to be buried in the hydrophobic interior of the enzyme, where it makes hydrogen-bonding...
Wynne, S A, Nicholls, D J, Scawen, M D, Sundaram, T K
The gene encoding the tetrameric malate dehydrogenase (MDH) in a thermophilic Bacillus species (BI) has been cloned in an Escherichia coli plasmid. The nucleotide sequence of the gene, the first to...
Alldread, R M, Halsall, D M, Clarke, A R, Sundaram, T K, Atkinson, T, Scawen, M D, ...
The nucleotide-binding fold of many NAD(+)-dependent dehydrogenases contains a conserved acidic amino acid residue which hydrogen-bonds with the 2'- and 3'-hydroxy groups of the adenine-ribose of the...
Moola, Z B, Scawen, M D, Atkinson, T, Nicholls, D J
This study shows that the antigenicity of Erwinia chrysanthemi L-asparaginase can be reduced by site-directed mutagenesis. Ten B-cell epitopes of the enzyme were identified using synthetic...
Nobbs, T J, Cortés, A, Gelpi, J L, Holbrook, J J, Atkinson, T, Scawen, M D, ...
The X-ray structure of lactate dehydrogenase (LDH) shows the side-chain carboxylate group of Asp-143 to be buried in the hydrophobic interior of the enzyme, where it makes hydrogen-bonding...
Wynne, S A, Nicholls, D J, Scawen, M D, Sundaram, T K
The gene encoding the tetrameric malate dehydrogenase (MDH) in a thermophilic Bacillus species (BI) has been cloned in an Escherichia coli plasmid. The nucleotide sequence of the gene, the first to...
Malate dehydrogenase: a model for structure, evolution, and catalysis.
Goward, C. R., Nicholls, D. J.
Malate dehydrogenases are widely distributed and alignment of the amino acid sequences show that the enzyme has diverged into 2 main phylogenetic groups. Multiple amino acid sequence alignments of...