Weed Manager-A model-based decision support system for weed management in arable crops (2009)
Parsons, David J., Benjamin, L. R., Clarke, J., Ginsburg, D., Mayes, A., Milne, A. E., ...
Weed Manager is a model-based decision support system to assist arable farmers and advisers in weed control decisions on two time scales: within a single season and over several years in a rotation....
Linking systems biology models to data: a stochastic kinetic model of p53 oscillations (2009)
D. A. Henderson, D. J. Wilkinson
This chapter considers the assessment and refinement of a dynamic stochastic process model of the cellular response to DNA damage. The proposed model is a complex nonlinear continuous time latent...
Pharyngeal pressure with high-flow nasal cannulae in premature infants (2008)
Wilkinson, D. J., Andersen, Chad Campion, Smith, K., Holberton, J.
D J Wilkinson, C C Andersen, K Smith and J Holberton
Pharyngeal pressure with high-flow nasal cannulae in premature infants (2008)
Wilkinson, D. J., Andersen, Chad Campion, Smith, K., Holberton, J.
D J Wilkinson, C C Andersen, K Smith and J Holberton
Local computation of influence propagation through Bayes linear belief networks (2007)
In recent years there has been interest in the theory of local computation over probabilistic Bayesian graphical models. In this paper, local computation over Bayes linear belief networks is shown to...
Topics of particular interest are: Bayesian applications, (2007)
R J. Avery, P. J. Avery, R. J. Boys, R. J. Boys, D. A. Henderson, ...
Statistical modelling of DNA sequences. Biomathematical models of cell ageing. Statistical modelling of DNA sequences
Sevoflurane and analgesia (2007)
Grover, S., Wilkinson, D. J., Yeo, S. T., Holdcroft, A., Yentis, S. M.
Bayesian methods in bioinformatics and computational systems biology (2007)
Bayesian methods are valuable, inter alia, whenever there is a need to extract information from data that is uncertain or subject to any kind of error or noise (including measurement error and...
On Bayesian Inference for Stochastic Kinetic Models Using Diffusion Approximations (2004)
This paper is concerned with the Bayesian estimation of stochastic rate constants in the context of dynamic models of intra-cellular processes. The underlying discrete stochastic kinetic model is...
Index-based policies for discounted multi-armed bandits on parallel machines (2000)
Glazebrook, K. D., Wilkinson, D. J.
We utilize and develop elements of the recent achievable region account of Gittins indexation by Bertsimas and Niño-Mora to design index-based policies for discounted multi-armed bandits on parallel...
This paper concerns the geometric treatment of graphical models using Bayes linear methods. We introduce Bayes linear separation as a second order generalised conditional independence relation, and...
Mercury Blockade of Thiazide-Sensitive NaCl Cotransport in Flounder Urinary Bladder (1993)
Wilkinson, D. J., Post, M. A., Venglarik, C., Chang, D.
The effects of HgCl2 on ion transport were investigated using isolated sheets of flounder urinary bladder, a model epithelium that is capable of electrically silent NaCl absorption and electrogenic K...
MEPTAZINOL--A CAUSE OF RESPIRATORY DEPRESSION IN GENERAL ANAESTHESIA (1985)
WILKINSON, D. J., O'CONNOR, S. A., DICKSON, G. R., DRAKE, H. F.
The respiratory effects of meptazinol 1 mg kg−1 have been compared with those of pethidine 0.5 mg kg−1 and 1 mg kg−1 in a double-blind trial in 30 patients undergoing arthroscopic meniscectomy...
Smit, L S, Wilkinson, D J, Mansoura, M K, Collins, F S, Dawson, D C
The cystic fibrosis transmembrane conductance regulator (CFTR), a member of the traffic ATPase superfamily, possesses two putative nucleotide-binding folds (NBFs). The NBFs are sufficiently similar...
Tetraethylammonium-sensitive apical K+ channels mediating K+ secretion by turtle colon.
Wilkinson, D J, Kushman, N L, Dawson, D C
1. Apical membrane K+ channels in turtle colon were identified and characterized using current fluctuation analysis. 2. Under short-circuit conditions in NaCl-Ringer solution, the power density...
Smit, L S, Wilkinson, D J, Mansoura, M K, Collins, F S, Dawson, D C
The cystic fibrosis transmembrane conductance regulator (CFTR), a member of the traffic ATPase superfamily, possesses two putative nucleotide-binding folds (NBFs). The NBFs are sufficiently similar...
Tetraethylammonium-sensitive apical K+ channels mediating K+ secretion by turtle colon.
Wilkinson, D J, Kushman, N L, Dawson, D C
1. Apical membrane K+ channels in turtle colon were identified and characterized using current fluctuation analysis. 2. Under short-circuit conditions in NaCl-Ringer solution, the power density...
Modelling the checkpoint response to telomere uncapping in budding yeast
Proctor, C.J, Lydall, D.A, Boys, R.J, Gillespie, C.S, Shanley, D.P, Wilkinson, D.J, ...
One of the DNA damage-response mechanisms in budding yeast is temporary cell-cycle arrest while DNA repair takes place. The DNA damage response requires the coordinated interaction between DNA repair...
Plasma lignocaine levels during transurethral prostatectomy.
Eardley, I., Broome, G. D., Murray, A., Ramsay, J. W., Whitfield, H. N., Wilkinson, D. J.
It has been reported that transurethral absorption of lignocaine may cause systemic toxicity when associated with mucosal damage within the urethra. We measured the serum levels of lignocaine in 30...
White, A. P., Laurent, S., Wilkinson, D. J.
A randomised, double-blind study was conducted to assess the influence of intra-articular and subcutaneous prilocaine with adrenaline on postoperative pain in day case arthroscopy of the knee. The...
Addinall, S. G., Downey, M., Yu, M., Zubko, M. K., Dewar, J., Leake, A., ...
In Saccharomyces cerevisiae, Cdc13 binds telomeric DNA to recruit telomerase and to “cap” chromosome ends. In temperature-sensitive cdc13-1 mutants telomeric DNA is degraded and cell-cycle...
Death in the neonatal intensive care unit: changing patterns of end of life care over two decades
Wilkinson, D J, Fitzsimons, J J, Dargaville, P A, Campbell, N T, Loughnan, P M, McDougall, P N, ...
Functional neuroimaging and withdrawal of life-sustaining treatment from vegetative patients
Wilkinson, D J, Kahane, G, Horne, M, Savulescu, J
Recent studies using functional magnetic resonance imaging of patients in a vegetative state have raised the possibility that such patients retain some degree of consciousness. In this paper, the...