D. L.

Massive-Star Supernovae as Major Dust Factories (2006)

  • Sugerman,
  • B.E.K.,
  • Ercolano,
  • B.,
  • Barlow,
  • M.J.,
  • ...

We present late-time optical and mid-infrared observations of the Type II supernova 2003gd in the galaxy NGC 628. Mid-infrared excesses consistent with cooling dust in the ejecta are observed 499 to...

Sea ice is a mushy layer (2006)

  • Feltham,
  • D.L.,
  • Untersteiner,
  • N.,
  • Wettlaufer,
  • J.S.,
  • ...

Tissue deformation and shape models in image-guided interventions: a discussion paper (2005)

  • Hawkes,
  • D.J.,
  • Barratt,
  • D.,
  • Blackall,
  • J.M.,
  • ...

This paper promotes the concept of active models in image-guided interventions. We outline the limitations of the rigid body assumption in image-guided interventions and describe how intraoperative...

Heterogeneous duplications in patients with Pelizaeus-Merzbacher disease suggest a mechanism of coupled homologous and nonhomologous recombination (2005)

  • Woodward,
  • K.J.,
  • Cundall,
  • M.,
  • Sperle,
  • K.,
  • ...

We describe genomic structures of 59 X-chromosome segmental duplications that include the proteolipid protein 1 gene (PLP1) in patients with Pelizaeus-Merzbacher disease. We provide the first report...

Regional variation of cerebral blood flow and arterial transit time in the normal and hypoperfused rat brain measured using continuous arterial spin labeling MRI (2005)

Continuous arterial spin labeling (CASL) is a noninvasive magnetic resonance (MR) method for measuring cerebral perfusion. In its most widely used form, CASL incorporates a postlabeling delay to...

Novel TRPM6 mutations in 21 families with primary hypomagnesemia and secondary Hypocalcemia (2005)

  • Schlingmann,
  • K.P.,
  • Sassen,
  • M.C.,
  • Weber,
  • S.,
  • ...

Primary hypomagnesemia with secondary hypocalcemia is a rare autosomal recessive disorder characterized by profound hypomagnesemia associated with hypocalcemia. Pathophysiology is related to impaired...

Gap junctions modulate interkinetic nuclear movement in retinal progenitor cells (2005)

During early retinal development, progenitor cells must divide repeatedly to expand the progenitor pool. During G(1) and G(2) of the cell cycle, progenitor cell nuclei migrate back-and- forth across...

Mannose-binding lectin enhances phagocytosis and killing of Neisseria meningitidis by human macrophages (2005)

Deficiency of mannose-binding lectin (MBL) is probably the most common human immunodeficiency and is associated with an increased risk of mucosally acquired infections including meningococcal...

A system for real-time XMR guided cardiovascular intervention (2005)

  • Rhode,
  • K.S.,
  • Sermesant,
  • M.,
  • Brogan,
  • D.,
  • ...

The hybrid magnetic resonance (MR)/X-ray suite (XMR) is a recently introduced imaging solution that provides new possibilities for guidance of cardiovascular catheterization procedures. We have...

Impact of electromagnetic field exposure limits in Europe: is the future of interventional MRI safe? (2005)

The European Union (EU) has recently introduced a directive that aims to protect workers from adverse effects of exposure to electromagnetic fields. All countries within the EU are required to...

Simulation of cardiac pathologies using an electromechanical biventricular model and XMR interventional imaging (2005)

  • Sermesant,
  • M.,
  • Rhode,
  • K.,
  • Sanchez-Ortiz,
  • G.I.,
  • ...

Simulating cardiac electromechanical activity is of great interest for a better understanding of pathologies and for therapy planning. Design and validation of such models is difficult due to the...

Induction of replication in human corneal endothelial cells by E2F2 transcription factor cDNA transfer (2005)

PURPOSE: Corneal endothelial cells in humans do not replicate to any meaningful extent. Diminishing density of the cell monolayer with age and in the disease states is a major cause of loss of...

Catheter tracking and visualization using 19F nuclear magnetic resonance (2004)

  • Kozerke,
  • S.,
  • Hegde,
  • S.,
  • Schaeffter,
  • T.,
  • ...

This work presents an investigation into catheter visualization and localization using 19F nuclear magnetic resonance (NMR) in conjunction with proton imaging. For this purpose, the imaging...

Non-rigid image registration: theory and practice (2004)

Image registration is an important enabling technology in medical image analysis. The current emphasis is on development and validation of application-specific non-rigid techniques, but there is...

Registered computed tomography images as an alternative to postimplantation magnetic resonance imaging in the assessment of subthalamic electrode placement (2004)

Magnetic resonance imaging (MRI) after implantation of electrodes in the subthalamic nuclei is currently performed at a number of sites, but a recent adverse incident and changes in MRI technology...

Ten years of preimplantation genetic diagnosis-aneuploidy screening: review of a multicenter report (2004)

Preimplantation genetic diagnosis of day 3 human embryos by fluorescent in situ hybridization has over the past 10 years increased in use as a screen for aneuploidy. Routine screening of...

Visualization and tracking of an inflatable balloon catheter using SSFP in a flow phantom and in the heart and great vessels of patients (2004)

  • Miquel,
  • M.E.,
  • Hegde,
  • S.,
  • Muthurangu,
  • V.,
  • ...

Passive catheter tracking involves direct interaction between the device and its surroundings, creating a local signal loss or enhancement of the image. Using only standard balloon catheters filled...

Low myo-inositol and high glutamine levels in the brain are associated with neuropsychological deterioration following induced hyperammonemia (2004)

The neuropsychological effect of hyperammonemia is variable. This study tests the hypothesis that the effect of ammonia on the neuropsychological function in patients with cirrhosis is determined by...

Systemic inflammatory response exacerbates the neuropsychological effects of induced hyperammonemia in cirrhosis (2004)

  • Shawcross,
  • D.L.,
  • Davies,
  • N.A.,
  • Williams,
  • R.,
  • ...

Background: Studies in acute liver failure show correlation between evidence of a systemic inflammatory response syndrome (SIRS) and progression of Hepatic Encephalopathy (HE). We tested the...

Worsening of cerebral hyperemia by the administration of terlipressin in acute liver failure with severe hepatic encephalopathy (2004)

There is increasing evidence that terlipressin is useful in patients with cirrhosis andhepatorenal syndrome, but there are no data of its use in patients with acute liverfailure (ALF) in whom...

Cardiac catheterisation guided by MRI in children and adults with congenital heart disease (2003)

  • Razavi,
  • R.,
  • Hill,
  • D.L.,
  • Keevil,
  • S.F.,
  • ...

BACKGROUND: Fluoroscopically guided cardiac catheterisation is an essential tool for diagnosis and treatment of congenital heart disease. Drawbacks include poor soft tissue visualisation and exposure...

Information theoretic similarity measures in non-rigid registration (2003)

Mutual Information (MI) and Normalised Mutual Information (NMI) have enjoyed success as image similarity measures in medical image registration. More recently, they have been used for non-rigid...

Measurement and analysis of brain deformation during neurosurgery (2003)

  • Hartkens,
  • T.,
  • Hill,
  • D.L.,
  • Castellano-Smith,
  • A.D.,
  • ...

Recent studies have shown that the surface of the brain is deformed by up to 20 mm after the skull is opened during neurosurgery, which could lead to substantial error in commercial image-guided...

Myocardial delineation via registration in a polar coordinate system (2003)

  • Noble,
  • N.M.,
  • Hill,
  • D.L.,
  • Breeuwer,
  • M.,
  • ...

RATIONALE AND OBJECTIVES: Cardiovascular disease is the number one cause of premature death in the western world. Analysis of cardiac function provides clinically useful diagnostic and prognostic...

Registration and tracking to integrate X-ray and MR images in an XMR facility (2003)

We describe a registration and tracking technique to integrate cardiac X-ray images and cardiac magnetic resonance (MR) images acquired from a combined X-ray and MR interventional suite (XMR)....

SMASH navigators (2003)

  • Bydder,
  • M.,
  • Atkinson,
  • D.,
  • Larkman,
  • D.J.,
  • ...

Three- and four-dimensional reconstruction of intra-cardiac anatomy from two-dimensional magnetic resonance images (2003)

The present study was designed to evaluate the feasibility and clinical usefulness of three-dimensional (3D) reconstruction of intra-cardiac anatomy from a series of two-dimensional (2D) MR images...

Three-dimensional magnetic resonance imaging of congenital cardiac anomalies (2003)

  • Razavi,
  • R.S.,
  • Hill,
  • D.L.,
  • Muthurangu,
  • V.,
  • ...

We describe a new method of three-dimensional magnetic resonance imaging of the heart that has been used to produce high quality diagnostic images in 274 patients with congenital cardiac disease,...

Zen and the art of medical image registration: correspondence, homology, and quality (2003)

Nonrigid registration (NRR) is routinely used in the study of neuroanatomy and function and is a standard component of analysis packages such as SPM. There remain many unresolved correspondence...

A study to evaluate the met and unmet needs of members belonging to Young Stroke groups affiliated with the Stroke Association (2003)

  • Low,
  • J.T.S.,
  • Kersen,
  • P.,
  • Ashburn,
  • A.,
  • ...

Purpose : To examine the met and unmet needs of young people with stroke who accessed services run by the Stroke Association. Methods : One hundred and thirty-five out of 200 members of 14...

Deforming a preoperative volume to represent the intraoperative scene (2002)

  • Penney,
  • G.P.,
  • Little,
  • J.A.,
  • Weese,
  • J.,
  • ...

Soft-tissue deformation can be a problem if a preoperative modality is used to help guide a surgical or interventional procedure. We present a method that can warp a preoperative CT image to...

Is gender selection an appropriate use of medical resources? (2002)

Gender selection by PGD is an appropriate use of medical resources. Children borne through PGD for gender determination would be welcome and would come into a couple's life at a planned, opportune...

DDAVP nasal spray for treatment of menorrhagia in women with inherited bleeding disorders: a randomized placebo-controlled crossover study (2002)

To assess DDAVP (1-deamino-8-D-arginine vasopressin; desmopressin) nasal spray in the management of menorrhagia in patients with inherited bleeding disorders, 39 women (aged 1850 years) with...

The unmet needs of young people who have had a stroke: results of a national UK survey (2002)

  • Kersten,
  • P.,
  • Low,
  • J.T.S.,
  • Ashburn,
  • A.,
  • ...

Background. Most stroke-related studies have consisted of people over the age of 65. This study examined the unmet needs of young people with stroke, living in community housing in the UK. Method:...

The use of nuchal translucency measurement and second trimester biochemical markers in screening for Down's Syndrome (2001)

  • Michailidis,
  • G.D.,
  • Spencer,
  • K.,
  • Economides,
  • D.L.

Objective To assess the effectiveness of antenatal screening for trisomy 21 by first trimester sonography followed by second trimester biochemical screening Design Retrospective five-year review....

Detailed three-dimensional fetal echocardiography facilitated by an Internet link (2001)

  • Michailidis,
  • G.D.,
  • Simpson,
  • J.M.,
  • Karidas,
  • C.,
  • ...

Objectives To assess whether a complete virtual cardiological examination can be achieved in stored three-dimensional volumes of the fetal heart, transmitted to a tertiary fetal cardiology center via...

Nuchal translucency measurement and pregnancy outcome in karyotypically normal fetuses (2001)

Objective The aim of the study was to evaluate the use of nuchal translucency measurement as a marker of adverse pregnancy outcome in karyotypically normal fetuses. Methods During the years 1995-99,...

Retrospective prenatal diagnosis of scimitar syndrome aided by three-dimensional power Doppler imaging (2001)

Scimitar syndrome is a rare malformation of the arterial supply and venous drainage of the lung. We report the case of a fetus that presented with cardiac asymmetry and malposition of the fetal...

The role of three-dimensional ultrasound in obstetrics (2001)

Three-dimensional ultrasound is a relatively new imaging modality with several potential advantages over conventional two-dimensional sonography. There is now increasing evidence that...

Reproductive choices of women in families with haemophilia (2000)

  • Kadir,
  • R.A.,
  • Sabin,
  • C.A.,
  • Goldman,
  • E.,
  • ...

To assess women's experiences in pregnancy and attitudes towards their reproductive choices, a structured questionnaire was sent to all obligate and potential carriers of haemophilia (A and B), aged...

Assessment of condoms as probe covers for transvaginal sonography (2000)

  • Amis,
  • S.,
  • Ruddy,
  • M.,
  • Kibbler,
  • C.C.,
  • ...

PURPOSE: This prospective study assessed the incidence of transvaginal probe contamination and breakage of condoms used to cover those probes during transvaginal sonography. METHODS: Over a 9-month...

Ultrasonographic markers for chromosomal abnormalities in women with negative nuchal translucency and second trimester maternal serum biochemistry (2000)

  • Verdin,
  • S.M.,
  • Whitlow,
  • B.J.,
  • Lazanakis,
  • M.,
  • ...

OBJECTIVE: To analyze the value of second trimester ultrasound examination among those women whose fetuses were indicated to be at low risk of chromosomal anomalies on the basis of both first...

Folic acid supplementation (2000)

Neural tube defects represent one of a limited number of congenital conditions for which primary prevention strategies are available. Despite strong clinical evidence to support the preventive effect...

Short Form 36 (SF-36) Health Survey questionnaire: which normative data should be used? Comparisons between the norms provided by the Omnibus Survey in Britain, the Health Survey for England and the Oxford Healthy Life Survey (1999)

  • Bowling,
  • A.,
  • Bond,
  • M.,
  • Jenkinson,
  • C.,
  • ...

Background Population norms for the attributes included in measurement scales are required to provide a standard with which scores from other study populations can be compared. This study aimed to...

Assessment of menstrual blood loss and gynaecological problems in patients with inherited bleeding disorders (1999)

Summary:- Menstral blood loss and gynaecological problems in aptients with inherited bleeding disorders were assessed in this study. One hundred and sixteen women, including 66 with Willebrand's...

Frequency of inherited bleeding disorders in women with menorrhagia (1998)

BACKGROUND: Although menorrhagia is a common gynaecological symptom, a specific cause is identified in less than 50% of affected women. We investigated the frequency of inherited bleeding disorders...

Pregnancy in women with von Willebrand's disease or factor XI deficiency (1998)

OBJECTIVE: To assess the obstetric outcome in women with von Willebrand's disease or factor XI deficiency. SETTING: Haemophilia Centre and Haemostasis Unit, The Royal Free Hospital. POPULATION: Women...

Employment and economic development :--a study in technical aspects /--by D. L. Narayana. (1958)

"This is an adaptation of the author's thesis, Andhra, 1955".

 
Additional Information

Publishing period:

1958 - 2006 (175)

Co-authors: