D. L. Barber

Publication List Details

Period

1979 - 1979

Number

19

Co-Authors

A calcineurin homologous protein inhibits GTPase-stimulated Na-H exchange.

Lin, X, Barber, D L

Activation of the ubiquitously expressed Na-H exchanger, NHE1, results in an increased efflux of intracellular H+. The increase in intracellular pH associated with this H+ efflux may contribute to...

The cytokine-activated tyrosine kinase JAK2 activates Raf-1 in a p21ras-dependent manner.

Xia, K, Mukhopadhyay, N K, Inhorn, R C, Barber, D L, Rose, P E, Lee, R S, ...

JAK2, a member of the Janus kinase superfamily was found to interact functionally with Raf-1, a central component of the ras/mitogen-activated protein kinase signal transduction pathway....

The Fanconi anemia polypeptide FACC is localized to the cytoplasm.

Yamashita, T, Barber, D L, Zhu, Y, Wu, N, D'Andrea, A D

Fanconi anemia (FA) is an autosomal recessive disease characterized by congenital anomalies, aplastic anemia, and chromosomal instability. A cDNA encoding the FA complementation group C (FACC)...

A single chicken oocyte plasma membrane protein mediates uptake of very low density lipoprotein and vitellogenin.

Stifani, S, Barber, D L, Nimpf, J, Schneider, W J

Specific cell-surface receptors mediate the uptake of plasma proteins into growing oocytes of oviparous species, thereby forming yolk. Quantitatively the most important yolk precursors are the...

Cloning and sequence analysis of cDNA for the canine neurotensin/neuromedin N precursor.

Dobner, P R, Barber, D L, Villa-Komaroff, L, McKiernan, C

Cloned cDNAs encoding neurotensin were isolated from a cDNA library derived from primary cultures of canine enteric mucosa cells. Nucleotide sequence analysis has revealed the primary structure of a...

A dominant negative erythropoietin (EPO) receptor inhibits EPO-dependent growth and blocks F-gp55-dependent transformation.

Barber, D L, DeMartino, J C, Showers, M O, D'Andrea, A D

The erythropoietin receptor (EPO-R), a member of the cytokine receptor superfamily, can be activated to signal cell growth by binding either EPO or F-gp55, the Friend spleen focus-forming virus...

p160ROCK mediates RhoA activation of Na-H exchange.

Tominaga, T, Ishizaki, T, Narumiya, S, Barber, D L

The ubiquitously expressed Na-H exchanger, NHE1, acts downstream of RhoA in a pathway regulating focal adhesion and actin stress fiber formation. p160ROCK, a serine/threonine protein kinase, is a...

Erythropoietin and interleukin-2 activate distinct JAK kinase family members.

Barber, D L, D'Andrea, A D

The erythropoietin (EPO) receptor and the interleukin-2 (IL-2) receptor beta-chain subunit are members of the cytokine receptor superfamily. They have conserved primary amino acid sequences in their...

A calcineurin homologous protein inhibits GTPase-stimulated Na-H exchange.

Lin, X, Barber, D L

Activation of the ubiquitously expressed Na-H exchanger, NHE1, results in an increased efflux of intracellular H+. The increase in intracellular pH associated with this H+ efflux may contribute to...

The cytokine-activated tyrosine kinase JAK2 activates Raf-1 in a p21ras-dependent manner.

Xia, K, Mukhopadhyay, N K, Inhorn, R C, Barber, D L, Rose, P E, Lee, R S, ...

JAK2, a member of the Janus kinase superfamily was found to interact functionally with Raf-1, a central component of the ras/mitogen-activated protein kinase signal transduction pathway....

The Fanconi anemia polypeptide FACC is localized to the cytoplasm.

Yamashita, T, Barber, D L, Zhu, Y, Wu, N, D'Andrea, A D

Fanconi anemia (FA) is an autosomal recessive disease characterized by congenital anomalies, aplastic anemia, and chromosomal instability. A cDNA encoding the FA complementation group C (FACC)...

A single chicken oocyte plasma membrane protein mediates uptake of very low density lipoprotein and vitellogenin.

Stifani, S, Barber, D L, Nimpf, J, Schneider, W J

Specific cell-surface receptors mediate the uptake of plasma proteins into growing oocytes of oviparous species, thereby forming yolk. Quantitatively the most important yolk precursors are the...

Cloning and sequence analysis of cDNA for the canine neurotensin/neuromedin N precursor.

Dobner, P R, Barber, D L, Villa-Komaroff, L, McKiernan, C

Cloned cDNAs encoding neurotensin were isolated from a cDNA library derived from primary cultures of canine enteric mucosa cells. Nucleotide sequence analysis has revealed the primary structure of a...

A dominant negative erythropoietin (EPO) receptor inhibits EPO-dependent growth and blocks F-gp55-dependent transformation.

Barber, D L, DeMartino, J C, Showers, M O, D'Andrea, A D

The erythropoietin receptor (EPO-R), a member of the cytokine receptor superfamily, can be activated to signal cell growth by binding either EPO or F-gp55, the Friend spleen focus-forming virus...

Erythropoietin and interleukin-2 activate distinct JAK kinase family members.

Barber, D L, D'Andrea, A D

The erythropoietin (EPO) receptor and the interleukin-2 (IL-2) receptor beta-chain subunit are members of the cytokine receptor superfamily. They have conserved primary amino acid sequences in their...

p160ROCK mediates RhoA activation of Na-H exchange.

Tominaga, T, Ishizaki, T, Narumiya, S, Barber, D L

The ubiquitously expressed Na-H exchanger, NHE1, acts downstream of RhoA in a pathway regulating focal adhesion and actin stress fiber formation. p160ROCK, a serine/threonine protein kinase, is a...

Expression of TEL-JAK2 in primary human hematopoietic cells drives erythropoietin-independent erythropoiesis and induces myelofibrosis in vivo

Kennedy, J. A., Barabé, F., Patterson, B. J., Bayani, J., Squire, J. A., Barber, D. L., ...

Activation of JAK2 by chromosomal translocation or point mutation is a recurrent event in hematopoietic malignancies, including acute leukemias and myeloproliferative disorders. Although the effects...

Structural model and functional significance of pH-dependent talin–actin binding for focal adhesion remodeling

Srivastava, J., Barreiro, G., Groscurth, S., Gingras, A. R., Goult, B. T., Critchley, D. R., ...

Actin filament binding by the focal adhesion (FA)-associated protein talin stabilizes cell-substrate adhesions and is thought to be rate-limiting in cell migration. Although F-actin binding by talin...