Bedoya, G., Montoya, P., Garcia, J., Soto, I., Bourgeois, S., Carvajal, L., ...
Although it is well established that Hispanics generally have a mixed Native American, African, and European ancestry, the dynamics of admixture at the foundation of Hispanic populations is...
Y-chromosome evidence for differing ancient demographic histories in the Americas (2003)
Salzano, F.M., Thomas, M.G., Stuart, S., Nasanen, S.P.K., Bau, C.H.D., ...
To scrutinize the male ancestry of extant Native American populations, we examined eight biallelic and six microsatellite polymorphisms from the nonrecombining portion of the Y chromosome, in 438...
Allelic losses and DNA methylation at DNA mismatch repair loci in sporadic colorectal cancer (1998)
Benachenhou, N, Guiral, S, Gorska-Flipot, I, Michalski, R, Labuda, D, Sinnett, D
EVOLUTION OF MOUSE B1 REPEATS - 7SL RNA FOLDING PATTERN CONSERVED (1991)
Labuda, D., Sinnett, D., Richer, C., Deragon, J. M., Striker, G.
Labuda, D., Striker, G., Grosjean, H., Porschke, D.
The binding of yeast tRNAPha to UUCA, UUCC, UUCCC, UUCUUCU, U4 U5 U6 and U7 was analysed by fluorescence temperature jump and equilibrium sedimentation measurements. In all cases the two observed...
Isolation and chromatographic behaviour of phenylalanine tRNA from barley embryos (1974)
Labuda, D., Janowicz, Z., Haertle, T., Augustyniak, J.
Two fractions of phenylalanine tRNA (tRNA1Pne and tRNA2Phe) were purified by BD-cellulose and RPC-5 chromatography of crude tRNA isolated from barley embryos. Successive RPC-5 rechromatography runs...
Zietkiewicz, E, Labuda, M, Sinnett, D, Glorieux, F H, Labuda, D
We present the use of our recently described multiple-loci polymorphic DNA markers ("alumorphs") for linkage mapping of the human genome. By using the polymerase chain reaction (PCR) with an...
Mitchell, G A, Labuda, D, Fontaine, G, Saudubray, J M, Bonnefont, J P, Lyonnet, S, ...
In studies of mutations causing deficiency of ornithine delta-aminotransferase (EC 2.6.1.13), we found an allele whose mature mRNA has a 142-nucleotide insertion at the junction of sequences from...
Ubiquitous mammalian-wide interspersed repeats (MIRs) are molecular fossils from the mesozoic era.
Jurka, J, Zietkiewicz, E, Labuda, D
Short interspersed elements (SINEs) are ubiquitous in mammalian genomes. Remarkable variety of these repeats among placental orders indicates that most of them amplified in each lineage...
A young Alu subfamily amplified independently in human and African great apes lineages.
Zietkiewicz, E, Richer, C, Makalowski, W, Jurka, J, Labuda, D
A variety of Alu subfamilies amplified in primate genomes at different evolutionary time periods. Alu Sb2 belongs to a group of young subfamilies with a characteristic two-nucleotide deletion at...
Sequence conservation in Alu evolution.
A statistical analysis of a set of genomic human Alu elements is based on a published alignment and a recent classification of these sequences. After separation of the Alu sequences into families,...
Mechanism of codon recognition by transfer RNA studied with oligonucleotides larger than triplets.
Labuda, D, Striker, G, Grosjean, H, Porschke, D
The binding of yeast tRNAPhe to UUCA, UUCC, UUCCC, UUCUUCU, U4, U5, U6 and U7 was analysed by fluorescence temperature jump and equilibrium sedimentation measurements. In all cases the two observed...
Isolation and chromatographic behaviour of phenylalanine tRNA from barley embryos
Labuda, D., Janowicz, Z., Haertle, T., Augustyniak, J.
Two fractions of phenylalanine tRNA (tRNAPhe1 and tRNAPhe2) were purified by BD-cellulose and RPC-5 chromatography of crude tRNA isolated from barley embryos. Successive RPC-5 rechromatography runs...
Reverse transcriptase activity from human embryonal carcinoma cells NTera2D1.
Deragon, J M, Sinnett, D, Labuda, D
We have identified an RNA-dependent DNA polymerase activity in the microsomal fraction of human pluri-potential embryonal carcinoma cells NTera2D1, which are known to express the full length coding...
Jaruzelska, J, Zietkiewicz, E, Batzer, M, Cole, D E, Moisan, J P, Scozzari, R, ...
With 10 segregating sites (simple nucleotide polymorphisms) in the last intron (1089 bp) of the ZFX gene we have observed 11 haplotypes in 336 chromosomes representing a worldwide array of 15 human...
Archaic lineages in the history of modern humans.
Labuda, D, Zietkiewicz, E, Yotova, V
An important question in the ongoing debate on the origin of Homo sapiens is whether modern human populations issued from a single lineage or whether several, independently evolving lineages...
Zietkiewicz, E, Labuda, M, Sinnett, D, Glorieux, F H, Labuda, D
We present the use of our recently described multiple-loci polymorphic DNA markers ("alumorphs") for linkage mapping of the human genome. By using the polymerase chain reaction (PCR) with an...
Mitchell, G A, Labuda, D, Fontaine, G, Saudubray, J M, Bonnefont, J P, Lyonnet, S, ...
In studies of mutations causing deficiency of ornithine delta-aminotransferase (EC 2.6.1.13), we found an allele whose mature mRNA has a 142-nucleotide insertion at the junction of sequences from...
Ubiquitous mammalian-wide interspersed repeats (MIRs) are molecular fossils from the mesozoic era.
Jurka, J, Zietkiewicz, E, Labuda, D
Short interspersed elements (SINEs) are ubiquitous in mammalian genomes. Remarkable variety of these repeats among placental orders indicates that most of them amplified in each lineage...
A young Alu subfamily amplified independently in human and African great apes lineages.
Zietkiewicz, E, Richer, C, Makalowski, W, Jurka, J, Labuda, D
A variety of Alu subfamilies amplified in primate genomes at different evolutionary time periods. Alu Sb2 belongs to a group of young subfamilies with a characteristic two-nucleotide deletion at...
Sequence conservation in Alu evolution.
A statistical analysis of a set of genomic human Alu elements is based on a published alignment and a recent classification of these sequences. After separation of the Alu sequences into families,...
Mechanism of codon recognition by transfer RNA studied with oligonucleotides larger than triplets.
Labuda, D, Striker, G, Grosjean, H, Porschke, D
The binding of yeast tRNAPhe to UUCA, UUCC, UUCCC, UUCUUCU, U4, U5, U6 and U7 was analysed by fluorescence temperature jump and equilibrium sedimentation measurements. In all cases the two observed...
Isolation and chromatographic behaviour of phenylalanine tRNA from barley embryos
Labuda, D., Janowicz, Z., Haertle, T., Augustyniak, J.
Two fractions of phenylalanine tRNA (tRNAPhe1 and tRNAPhe2) were purified by BD-cellulose and RPC-5 chromatography of crude tRNA isolated from barley embryos. Successive RPC-5 rechromatography runs...
Reverse transcriptase activity from human embryonal carcinoma cells NTera2D1.
Deragon, J M, Sinnett, D, Labuda, D
We have identified an RNA-dependent DNA polymerase activity in the microsomal fraction of human pluri-potential embryonal carcinoma cells NTera2D1, which are known to express the full length coding...
Jaruzelska, J, Zietkiewicz, E, Batzer, M, Cole, D E, Moisan, J P, Scozzari, R, ...
With 10 segregating sites (simple nucleotide polymorphisms) in the last intron (1089 bp) of the ZFX gene we have observed 11 haplotypes in 336 chromosomes representing a worldwide array of 15 human...
Archaic lineages in the history of modern humans.
Labuda, D, Zietkiewicz, E, Yotova, V
An important question in the ongoing debate on the origin of Homo sapiens is whether modern human populations issued from a single lineage or whether several, independently evolving lineages...
Labuda, M., Labuda, D., Korab-Laskowska, M., Cole, D. E., Zietkiewicz, E., Weissenbach, J., ...
Pseudo-vitamin D-deficiency rickets (PDDR) was mapped close to D12S90 and between proximal D12S312 and distal (D12S305, D12S104) microsatellites that were subsequently found on a single YAC clone....
Fraction of Informative Recombinations: A Heuristic Approach to Analyze Recombination Rates
In this article we present a new heuristic approach (informative recombinations, InfRec) to analyze recombination density at the sequence level. InfRec is intuitive and easy and combines previously...
Genomic loci susceptible to replication errors in cancer cells.
Krajinovic, M., Richer, C., Gorska-Flipot, I., Gaboury, L., Novakovic, I., Labuda, D., ...
Microsatellite instability due to a deficiency in DNA mismatch repair is characteristic of a replication error (RER) phenotype. This widespread genomic instability is well documented in hereditary...
Benachenhou, N, Guiral, S, Gorska-Flipot, I, Labuda, D, Sinnett, D
To study the involvement of DNA mismatch-repair genes in sporadic breast cancer, matched normal and tumoral DNA samples of 22 patients were analysed for genetic instability and loss of heterozygosity...