D. M.
Sensorimotor attenuation by central motor command signals in the absence of movement (2006)
- Voss,
- M.,
- Ingram,
- J.N.,
- Haggard,
- P.,
- ...
- Pickup,
- D.M.,
- Ahmed,
- I.,
- FitzGerald,
- V.,
- ...
Progressive cone and cone-rod dystrophies: Phenotypes and underlying molecular genetic basis. (2006)
- Wilton-Ely,
- J.D.E.T.,
- Wang,
- M.,
- Benoit,
- D.M.,
- ...
- Ho,
- T.K.,
- Rajkumar,
- V.,
- Ponticos,
- M.,
- ...
Objective: The potent physiologic endogenous angiogenic response to ischemic stimuli is often suboptimal, and therefore, a better understanding of the basic mechanisms is essential for the use in...
Ultrasound guided injection and occlusion of the trachea in fetal sheep. (2006)
- David,
- A.L.,
- Weisz,
- B.,
- Gregory,
- L.,
- ...
- Wu,
- H.,
- Cowing,
- J.A.,
- Michaelides,
- M.,
- ...
- POSSATTI,
- D.M
Trabalho apresentado no Intercom Júnior, evento componente do XXVIII Congresso Brasileiro de Ciências da Comunicação, Rio de Janeiro, RJ, 05-09,setembro,2005 Daniele...
- COGO,
- D.M
Trabalho apresentado no NP 12 - Comunicação para a Cidadania no XXVII Congresso Brasileiro de Ciências da Comunicação, Porto Alegre RS, 2004. Esse texto busca...
- COGO,
- D.M
Trabalho apresentado no NP12 - Comunicação para a Cidadania durante o XXVIII Congresso Brasileiro de Ciências da Comunicação, Rio de Janeiro, RJ,...
Andersen-Tawil syndrome - new potassium channel mutations and possible phenotypic variation (2005)
- Davies,
- N.P.,
- Imbrici,
- P.,
- Fialho,
- D.,
- ...
Disorders of body schema (2005)
- Haggard,
- P.,
- Wolpert,
- D.M.
Application of soft tissue modelling to image-guided surgery (2005)
The deformation of soft tissue compromises the accuracy of image-guided surgery based on preoperative images, and restricts its applicability to surgery on or near bony structures. One way to...
Preconditioning of the myocardium rapidly induces a number of transcription factors, which are likely to be responsible for a cascade of transcriptional changes underlying the development of delayed...
Background Total lymphocyte count has been proposed as an alternative to the percentage of CD4+ T-cells to indicate when antiretroviral therapy should be started in children with HIV in resource-poor...
The use of the Montgomery T-tube in difficult paediatric airways (2005)
OBJECTIVE:: We report our experience of using Montgomery T-tubes in children. METHOD:: A retrospective review of medical records was performed. Data collected included particular clinical...
- Melvin,
- D.M.,
- Dodds,
- P.,
- Real,
- M.,
- ...
Objectives and methods: To investigate the relationship between cell-associated HIV-1 dynamics and recent thymic T-cell emigrants, HIV-1 DNA and T-cell receptor rearrangement excision circles (TREC,...
The IGF system is one of the most important endocrine and paracrine growth factor systems that regulate fetal and placental growth. We hypothesized that intrauterine growth restriction (IUGR) in...
- Charakida,
- M.,
- Donald,
- A.E.,
- Green,
- H.,
- ...
BACKGROUND: Premature cardiovascular disease is increasingly recognized in HIV-infected patients, but the mechanisms involved are unclear. The purpose of this study was to determine the impact of HIV...
The molecular pathogenesis of type 1 von Willebrand disease (VWD) is uncertain in most patients. We examined 30 type 1 VWD families in the UK Haemophilia Centre Doctors' Organization study....
How we do it: BAHA positioning in patients with microtia requiring auricular reconstruction (2005)
- Bajaj,
- Y.,
- Wyatt,
- M.E.,
- Gault,
- D.,
- ...
Bilateral microtia is a challenging problem as these patients require both reconstruction of the auricle and rehabilitation of hearing. Our aim was to find the optimal position for bone-anchored...
A detailed phenotypic study of "cone dystrophy with supernormal rod ERG" (2005)
AIMS: To characterise the detailed phenotype of "cone dystrophy with supernormal rod ERG" in a case series of 10 patients. METHODS: 10 affected patients were examined clinically and underwent colour...
AIM: To characterise the phenotype of an autosomal dominant cone-rod dystrophy (CORD7) associated with the Arg844His mutation in RIM1. METHODS: Eight members of a four generation, non-consanguineous...
- Michaelides,
- M.,
- Johnson,
- S.,
- Simunovic,
- M.P.,
- ...
AIM: To perform a detailed clinical and psychophysical assessment of the members of three British families affected with blue cone monochromatism (BCM), and to determine the molecular basis of...
The potential for trichromacy in mammals, thought to be unique to primates, was recently discovered in two Australian marsupials. Whether the presence of three cone types, sensitive to short- (SWS),...
- Michaelides,
- M.,
- Holder,
- G.E.,
- Bradshaw,
- K.,
- ...
PURPOSE: To determine the underlying molecular genetic basis of a retinal dystrophy identified in a 5-generation family, and to examine the phenotype and degree of intrafamilial variability. DESIGN:...
Isolation and characterization of murine Cds (CDP-diacylglycerol synthase) 1 and 2 (2005)
- Inglis-Broadgate,
- S.L.,
- Ocaka,
- L.,
- Banerjee,
- R.,
- ...
Phototransduction in Drosophila is a phosphoinositide-mediated signalling pathway. Phosphatidylinositol 4,5-bisphosphate (PIP2) plays a central role in this process, and its levels are tightly...
- Michaelides,
- M.,
- Wilkie,
- S.E.,
- Jenkins,
- S.,
- ...
PURPOSE: To determine the underlying molecular genetic basis of a retinal dystrophy identified in a 4-generation family and to examine the phenotype and the degree of intrafamilial variability....
X-linked cone dysfunction syndrome with myopia and protanopia (2005)
- Michaelides,
- M.,
- Johnson,
- S.,
- Bradshaw,
- K.,
- ...
PURPOSE: To perform a detailed clinical, psychophysical, and molecular assessment of members of 4 families with an unusual X-linked cone dysfunction syndrome associated with myopia. PARTICIPANTS:...
- Muttukrishna,
- S.,
- McGarrigle,
- H.,
- Wakim,
- R.,
- ...
A remarkable non-Monolitical chain-lenght dependence: diffusion of n-alkanes in Zeolites LTA. (2005)
- Brandani,
- A.,
- Caro,
- J.,
- Jobic,
- H.,
- ...
- Jobic,
- H.,
- Kärger,
- J.,
- Krause,
- C.,
- ...
North Pacific seasonality and the glaciation of North America 2.7 million years ago (2005)
In the context of gradual Cenozoic cooling, the timing of the onset of significant Northern Hemisphere glaciation 2.7 million years ago is consistent with Milankovitch's orbital theory, which posited...
Klippel-Trenaunay-Weber syndrome (KTWS) is a congenital disorder characterized by a triad of varicose veins and venous malformation involving one or more extremities, cutaneous haemangioma, and...
- Walker,
- A.S.,
- Doerholt,
- K.,
- Sharland,
- M.,
- ...
OBJECTIVE: To evaluate the effect of age, CD4 percentage (CD4%) and plasma HIV-1 RNA on response to highly active antiretroviral therapy (HAART) in previously untreated children. DESIGN: Cohort...
An autosomal recessive cone-rod dystrophy associated with amelogenesis imperfecta (2004)
- Michaelides,
- M.,
- Bloch-Zupan,
- A.,
- Holder,
- G.E.,
- ...
- Haggard,
- P.,
- Wolpert,
- D.M.
Failure to consolidate the consolidation theory of learning for sensorimotor adaptation tasks (2004)
- Caithness,
- G.,
- Osu,
- R.,
- Bays,
- P.M.,
- ...
In order to investigate the mechanism of As release to anoxic ground water in alluvial aquifers, the authors sampled ground waters from 3 piezometer nests, 79 shallow (80 m) wells, in an area 750 m...
- Hausenloy,
- D.J.,
- Wynne,
- A.,
- Duchen,
- M.,
- ...
OBJECTIVE: To describe changes in demographic factors, disease progression, hospital admissions, and use of antiretroviral therapy in children with HIV. DESIGN: Active surveillance through the...
- Dunn,
- D.,
- Gibb,
- D.M.,
- HIV Paediatric Prognostic Markers Collaborative Study Group.
p53 down-regulation: a new molecular mechanism involved in ischaemic preconditioning. (2003)
Ischaemic preconditioning is associated with the activation of prosurvival mechanisms. Here we demonstrate that following a preconditioning protocol, the proapoptotic p53 is inactivated possibly via...
Beauty in a smile: the role of medial orbitofrontal cortex in facial attractiveness (2003)
- O'Doherty,
- J.,
- Winston,
- J.,
- Critchley,
- H.D.,
- ...
- Thiruchelvam,
- N.,
- Nyirady,
- P.,
- Peebles,
- D.M.,
- ...
During organogenesis, net growth of tissues is determined by a balance between proliferation, hypertrophy, and apoptotic death. Human fetal bladder outflow obstruction is a major cause of end-stage...
Nevirapine use in HIV-1-infected children (2003)
- Verweel,
- G.,
- Sharland,
- M.,
- Lyall,
- H.,
- ...
OBJECTIVES: To evaluate the safety, efficacy, and clinical, virological, and immunological responses in HIV-1-infected children receiving nevirapine as part of combination antiretroviral therapy...
Risk factors for Kaposi's sarcoma: A case-control study of HIV- seronegative people in Uganda (2003)
- Ziegler,
- J.,
- Newton,
- R.,
- Bourboulia,
- D.,
- ...
As part of a larger investigation of cancer in Uganda, we conducted a case-control study of Kaposi's sarcoma in human immunodeficiency virus-I (HIV)-seronegative adults presenting at hospitals in...
- Newton,
- R.,
- Ziegler,
- J.,
- Bourboulia,
- D.,
- ...
The genetics of inherited macular dystrophies (2003)
The inherited macular dystrophies comprise a heterogeneous group of disorders characterised by central visual loss and atrophy of the macula and underlying retinal pigment epithelium (RPE). The...
- Hunt,
- D.M.,
- Arrese,
- C.A.,
- Von Dornum,
- M.,
- ...
Rod visual pigment genes have been studied in a wide range of vertebrates including a number of mammalian species. However, no marsupials have yet been examined. To correct this omission, we have...
- Newton,
- R.,
- Ziegler,
- J.,
- Bourboulia,
- D.,
- ...
Human growth hormone (hGH) and bovine neurophysin (bNP) DNA reporter fragments were inserted into the rat vasopressin (VP) and oxytocin (OT) genes in a 44 kb cosmid construct used to generate two...
- Simopoulou,
- M.,
- Harper,
- J.C.,
- Fragouli,
- E.,
- ...
- Serhal,
- P.,
- Ranieri,
- D.M.,
- Khadum,
- I.,
- ...
P198, p194S
Variable K+ channel subunit dysfunction in inherited mutations of KCNA1 (2002)
- Rea,
- R.,
- Spauschus,
- A.,
- Eunson,
- L.H.,
- ...
- Paediatric European Network For Treatment Of AIDS (PENTA).,
- Gibb,
- D.M.,
- Babiker,
- A.
- Nyirady,
- P.,
- Thiruchelvam,
- N.,
- Fry,
- C.H.,
- ...
PURPOSE: Congenital bladder outflow obstruction caused by posterior urethral valves is a common cause of end stage renal failure in boys. We hypothesized that fetal bladder outflow obstruction...
Altered expression and allelic association of the hypervariable membrane mucin MUC1 (2002)
- Vinall,
- L.,
- King,
- M.,
- Novelli,
- M.,
- ...
- Vinall,
- L.E.,
- King,
- M.,
- Novelli,
- M.,
- ...
- Vinall,
- L.E.,
- King,
- M.,
- Novelli,
- M.,
- ...
- Baradue,
- P.,
- Hamilton,
- A.F.de C.,
- Wolpert,
- D.M.
OBJECTIVES: Ischemic preconditioning is known to protect the human heart from ischemic injury during coronary artery bypass graft (CABG) surgery but is not practised routinely. Adenosine A1 receptor...
- Meo,
- F.,
- Ranieri,
- D.M.,
- Khadum,
- I.,
- ...
- Doney,
- A.,
- Fischer,
- B.,
- Frew,
- D.,
- ...
Background: Variation at the PPARG locus may influence susceptibility to type 2 diabetes andrelated traits. The Pro12Ala polymorphism may modulate receptor activity and is associated withprotection...
Cell turnover in the developing and obstructed fetal bladder (2002)
- Thiruchelvam,
- N.,
- Nyirady,
- P.,
- Fry,
- C.H.,
- ...
Human epilepsy associated with dysfunction of the brain P/Q- type calcium channel (2001)
- Jouvenceau,
- A.,
- Eunson,
- L.H.,
- Spauschus,
- A.,
- ...
A penalized likelihood approach to image warping - Discussion (2001)
- Molchanov,
- I.,
- Jennison,
- C.,
- Ersboll,
- B.K.,
- ...
- Van Amelsvoort,
- T.A.,
- Abel,
- K.M.,
- Robertson,
- D.M.,
- ...
BACKGROUND: The sulfonylurea glibenclamide (Glib) abolishes the cardioprotective effect of ischemic preconditioning (IP), presumably by inhibiting mitochondrial K(ATP) channel opening in myocytes....
Not available
Apoptosis contributes to myocardial cell death during ischemia and reperfusion, especially during reperfusion. Growth factor "survival" signaling attenuates apoptosis. We therefore examined the...
OBJECTIVES: We assessed the effect of angiotensin-converting enzyme (ACE) inhibition in combination with a subthreshold preconditioning (PC) stimulus to elicit delayed preconditioning against...
- Kevelaitis,
- E.,
- Patel,
- A.P.,
- Oubenaissa,
- A.,
- ...
BACKGROUND: Cardiac harvest teams are usually committed to immediately transfer the explanted donor heart into its cold storage solution. We tested the opposite hypothesis that a brief prestorage...
Ischemic preconditioning (IP) reduces infarct size in young animals; however, its impact on aging is underinvestigated. The effect of variations in IP stimuli was studied in young, middle-aged, and...
OBJECTIVE: To determine whether exercise is capable of protecting the myocardium from experimental infarction and to explore the involvement of protein kinase C, a key signalling protein, in the...
- Minners,
- J.,
- Lacerda,
- L.,
- McCarthy,
- J.,
- ...
Pharmacological uncoupling of mitochondrial oxidation from phosphorylation promotes preconditioning-like cardioprotection in the isolated rat heart. We hypothesized that modest mitochondrial...
The "metabolic cocktail" comprising glucose-insulin-potassium administrated at reperfusion reduces infarct size in the in vivo rat heart. We propose that insulin is the major component mediating this...
- Botma,
- M.,
- Aymat,
- A.,
- Gault,
- D.,
- ...
- Kalache,
- K.D.,
- Masturzo,
- B.,
- Pierro,
- P.,
- ...
MUC1 in Heliobacter gastritis (2001)
- King,
- M.,
- Vinall,
- L.E.,
- Novelli,
- M.,
- ...
- Golgher,
- D.,
- Korangy,
- F.,
- Gao,
- B.,
- ...
There is accumulating evidence that CD4(+) T cell responses are important in antitumor immunity. Accordingly, we generated CD4(+) T cells against the murine CT26 colon cancer. Three of three...
- Phophong,
- P.,
- Ranieri,
- D.M.,
- Khadum,
- I.,
- ...
- Ranieri,
- D.M.,
- Phophong,
- P.,
- Khadum,
- I.,
- ...
Immune repopulation after HAART in previously untreated HIV-1- infected children (2000)
- Gibb,
- D.M.,
- Newberry,
- A.,
- Klein,
- N.,
- ...
Myocardial adaptation to ischaemia--the preconditioning phenomenon (1999)
- Carroll,
- R.,
- Yellon,
- D.M.
- Ranieri,
- D.M.,
- Quinn,
- F.,
- Makhlouf,
- A.,
- ...
- Peebles,
- D.M.,
- O'Brien,
- P.
The origins of utilisation behaviour (1989)
- Shallice,
- T.,
- Burgess,
- P.W.,
- Schon,
- F.,
- ...
- Dutt,
- D. M.,
- --1954-
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