D. Porte

Publication List Details

Period

1997 - 2005

Number

23

Co-Authors

FATTY ACID METABOLISM IN RAT INTESTINAL SEGMENTS (2005)

PORTE,D., ENTENMAN,C.

An in vitro prepara ion of rat intestinal segments capable of incorporating, esterifying and o idizing f tty acids is presented. After appropriate selection of tissue segments, reproducibility is...

DNA binding and transactivation properties of Fos variants with homodimerization capacity.

Porte, D, Oertel-Buchheit, P, John, M, Granger-Schnarr, M, Schnarr, M

The mammalian Fos and Fos-related proteins are unable to form homodimers and to bind DNA in the absence of a second protein, like c-Jun for example. In order to study the implications of hydrophobic...

Saturable transport of insulin from plasma into the central nervous system of dogs in vivo. A mechanism for regulated insulin delivery to the brain.

Baura, G D, Foster, D M, Porte, D, Kahn, S E, Bergman, R N, Cobelli, C, ...

By acting in the central nervous system, circulating insulin may regulate food intake and body weight. We have previously shown that the kinetics of insulin uptake from plasma into cerebrospinal...

Evidence for entry of plasma insulin into cerebrospinal fluid through an intermediate compartment in dogs. Quantitative aspects and implications for transport.

Schwartz, M W, Bergman, R N, Kahn, S E, Taborsky, G J, Fisher, L D, Sipols, A J, ...

To study the route by which plasma insulin enters cerebrospinal fluid (CSF), the kinetics of uptake from plasma into cisternal CSF of both insulin and [14C]inulin were analyzed during intravenous...

Insulin responses to glucose: evidence for a two pool system in man

Porte, D., Pupo, A. A.

Four rapid glucose injections of 5 g each were administered to normal young adult subjects before, during, and after an infusion of glucose. After the first glucose pulse, insulin responses measured...

Variations in circulating catecholamines fail to alter human platelet alpha-2-adrenergic receptor number or affinity for [3H]yohimbine or [3H]dihydroergocryptine.

Pfeifer, M A, Ward, K, Malpass, T, Stratton, J, Halter, J, Evans, M, ...

A series of studies were performed to determine the relationship between physiologic levels of circulating plasma norepinephrine and epinephrine and human platelet alpha-2 binding site number and the...

Diminished B cell secretory capacity in patients with noninsulin-dependent diabetes mellitus.

Ward, W K, Bolgiano, D C, McKnight, B, Halter, J B, Porte, D

In order to assess whether patients with noninsulin-dependent diabetes mellitus (NIDDM) possess normal insulin secretory capacity, maximal B cell responsiveness to the potentiating effects of glucose...

A role for alpha-adrenergic receptors in abnormal insulin secretion in diabetes mellitus.

Robertson, R P, Halter, J B, Porte, D

To determine whether endogenous alpha-adrenergic activity contributes to abnormal insulin secretion in nonketotic, hyperglycemic, diabetic patients, alpha-adrenergic blockade was produced in normal...

Hyperproinsulinemia is associated with increased beta cell demand after hemipancreatectomy in humans.

Seaquist, E R, Kahn, S E, Clark, P M, Hales, C N, Porte, D, Robertson, R P

The cause of disproportionate hyperproinsulinemia in patients with type II diabetes is controversial. To examine whether increased beta cell demand might contribute, we measured proinsulin and...

The effect of insulin dose on the measurement of insulin sensitivity by the minimal model technique. Evidence for saturable insulin transport in humans.

Prigeon, R L, Røder, M E, Porte, D, Kahn, S E

Administration of exogenous insulin during an intravenous glucose tolerance test allows the use of the minimal model technique to determine the insulin sensitivity index in subjects with reduced...

DNA binding and transactivation properties of Fos variants with homodimerization capacity.

Porte, D, Oertel-Buchheit, P, John, M, Granger-Schnarr, M, Schnarr, M

The mammalian Fos and Fos-related proteins are unable to form homodimers and to bind DNA in the absence of a second protein, like c-Jun for example. In order to study the implications of hydrophobic...

Saturable transport of insulin from plasma into the central nervous system of dogs in vivo. A mechanism for regulated insulin delivery to the brain.

Baura, G D, Foster, D M, Porte, D, Kahn, S E, Bergman, R N, Cobelli, C, ...

By acting in the central nervous system, circulating insulin may regulate food intake and body weight. We have previously shown that the kinetics of insulin uptake from plasma into cerebrospinal...

Evidence for entry of plasma insulin into cerebrospinal fluid through an intermediate compartment in dogs. Quantitative aspects and implications for transport.

Schwartz, M W, Bergman, R N, Kahn, S E, Taborsky, G J, Fisher, L D, Sipols, A J, ...

To study the route by which plasma insulin enters cerebrospinal fluid (CSF), the kinetics of uptake from plasma into cisternal CSF of both insulin and [14C]inulin were analyzed during intravenous...

Insulin responses to glucose: evidence for a two pool system in man

Porte, D., Pupo, A. A.

Four rapid glucose injections of 5 g each were administered to normal young adult subjects before, during, and after an infusion of glucose. After the first glucose pulse, insulin responses measured...

Variations in circulating catecholamines fail to alter human platelet alpha-2-adrenergic receptor number or affinity for [3H]yohimbine or [3H]dihydroergocryptine.

Pfeifer, M A, Ward, K, Malpass, T, Stratton, J, Halter, J, Evans, M, ...

A series of studies were performed to determine the relationship between physiologic levels of circulating plasma norepinephrine and epinephrine and human platelet alpha-2 binding site number and the...

Diminished B cell secretory capacity in patients with noninsulin-dependent diabetes mellitus.

Ward, W K, Bolgiano, D C, McKnight, B, Halter, J B, Porte, D

In order to assess whether patients with noninsulin-dependent diabetes mellitus (NIDDM) possess normal insulin secretory capacity, maximal B cell responsiveness to the potentiating effects of glucose...

A role for alpha-adrenergic receptors in abnormal insulin secretion in diabetes mellitus.

Robertson, R P, Halter, J B, Porte, D

To determine whether endogenous alpha-adrenergic activity contributes to abnormal insulin secretion in nonketotic, hyperglycemic, diabetic patients, alpha-adrenergic blockade was produced in normal...

Hyperproinsulinemia is associated with increased beta cell demand after hemipancreatectomy in humans.

Seaquist, E R, Kahn, S E, Clark, P M, Hales, C N, Porte, D, Robertson, R P

The cause of disproportionate hyperproinsulinemia in patients with type II diabetes is controversial. To examine whether increased beta cell demand might contribute, we measured proinsulin and...

The effect of insulin dose on the measurement of insulin sensitivity by the minimal model technique. Evidence for saturable insulin transport in humans.

Prigeon, R L, Røder, M E, Porte, D, Kahn, S E

Administration of exogenous insulin during an intravenous glucose tolerance test allows the use of the minimal model technique to determine the insulin sensitivity index in subjects with reduced...