Dominant lethal mutations in the plasma membrane H(+)-ATPase gene of Saccharomyces cerevisiae.
Harris, S L, Na, S, Zhu, X, Seto-Young, D, Perlin, D S, Teem, J H, ...
The plasma membrane H(+)-ATPase of Saccharomyces cerevisiae is an essential protein that is required to establish cellular membrane potential and maintain a normal internal pH. An Asp-378 to Asn...
Efficacy of Orally Delivered Cochleates Containing Amphotericin B in a Murine Model of Aspergillosis
Delmas, G., Park, S., Chen, Z. W., Tan, F., Kashiwazaki, R., Zarif, L., ...
Cochleates containing amphotericin B (CAMB) were administered orally at doses ranging from 0 to 40 mg/kg of body weight/day for 14 days in a murine model of systemic aspergillosis. The administration...
Cloning and characterization of the plasma membrane H(+)-ATPase from Candida albicans.
Monk, B C, Kurtz, M B, Marrinan, J A, Perlin, D S
The Candida albicans PMA1 gene was isolated from a genomic library by using a hybridization probe obtained from the PMA1 gene of Saccharomyces cerevisiae. The gene was localized to chromosome III of...
Pleiotropic plasma membrane ATPase mutations of Saccharomyces cerevisiae.
McCusker, J H, Perlin, D S, Haber, J E
We isolated a large number of mutations in the structural gene for the plasma membrane ATPase (PMA1) of Saccharomyces cerevisiae. These mutations were selected by their resistance to the...
Two α(1-3) Glucan Synthases with Different Functions in Aspergillus fumigatus
Beauvais, A., Maubon, D., Park, S., Morelle, W., Tanguy, M., Huerre, M., ...
α(1-3) glucan is a main component of the Aspergillus fumigatus cell wall. In spite of its importance, synthesis of this amorphous polymer has not been investigated to date. Two genes in A....
Park, S., Kelly, R., Kahn, J. Nielsen, Robles, J., Hsu, M.-J., Register, E., ...
An association between reduced susceptibility to echinocandins and changes in the 1,3-β-d-glucan synthase (GS) subunit Fks1p was investigated. Specific mutations in fks1 genes from Saccharomyces...
A Phe389Leu Substitution in ErgA Confers Terbinafine Resistance in Aspergillus fumigatus
Rocha, E. M. F., Gardiner, R. E., Park, S., Martinez-Rossi, N. M., Perlin, D. S.
Replacement of phenylalanine with leucine at position 391 in squalene epoxidase was identified as being responsible for terbinafine resistance in mutants of Aspergillus nidulans. The equivalent...
Dominant lethal mutations in the plasma membrane H(+)-ATPase gene of Saccharomyces cerevisiae.
Harris, S L, Na, S, Zhu, X, Seto-Young, D, Perlin, D S, Teem, J H, ...
The plasma membrane H(+)-ATPase of Saccharomyces cerevisiae is an essential protein that is required to establish cellular membrane potential and maintain a normal internal pH. An Asp-378 to Asn...
Efficacy of Orally Delivered Cochleates Containing Amphotericin B in a Murine Model of Aspergillosis
Delmas, G., Park, S., Chen, Z. W., Tan, F., Kashiwazaki, R., Zarif, L., ...
Cochleates containing amphotericin B (CAMB) were administered orally at doses ranging from 0 to 40 mg/kg of body weight/day for 14 days in a murine model of systemic aspergillosis. The administration...
Cloning and characterization of the plasma membrane H(+)-ATPase from Candida albicans.
Monk, B C, Kurtz, M B, Marrinan, J A, Perlin, D S
The Candida albicans PMA1 gene was isolated from a genomic library by using a hybridization probe obtained from the PMA1 gene of Saccharomyces cerevisiae. The gene was localized to chromosome III of...
Pleiotropic plasma membrane ATPase mutations of Saccharomyces cerevisiae.
McCusker, J H, Perlin, D S, Haber, J E
We isolated a large number of mutations in the structural gene for the plasma membrane ATPase (PMA1) of Saccharomyces cerevisiae. These mutations were selected by their resistance to the...
Two α(1-3) Glucan Synthases with Different Functions in Aspergillus fumigatus
Beauvais, A., Maubon, D., Park, S., Morelle, W., Tanguy, M., Huerre, M., ...
α(1-3) glucan is a main component of the Aspergillus fumigatus cell wall. In spite of its importance, synthesis of this amorphous polymer has not been investigated to date. Two genes in A....
Park, S., Kelly, R., Kahn, J. Nielsen, Robles, J., Hsu, M.-J., Register, E., ...
An association between reduced susceptibility to echinocandins and changes in the 1,3-β-d-glucan synthase (GS) subunit Fks1p was investigated. Specific mutations in fks1 genes from Saccharomyces...
A Phe389Leu Substitution in ErgA Confers Terbinafine Resistance in Aspergillus fumigatus
Rocha, E. M. F., Gardiner, R. E., Park, S., Martinez-Rossi, N. M., Perlin, D. S.
Replacement of phenylalanine with leucine at position 391 in squalene epoxidase was identified as being responsible for terbinafine resistance in mutants of Aspergillus nidulans. The equivalent...