Dal Porto, J, Johansen, T E, Catipović, B, Parfiit, D J, Tuveson, D, Gether, U, ...
Genetically engineered or chemically purified soluble monovalent major histocompatibility complex (MHC) molecules, which have previously been used to study T cells, have not blocked cytotoxic T-cell...
Tyrosine phosphorylation of phospholipase C induced by membrane immunoglobulin in B lymphocytes.
Carter, R H, Park, D J, Rhee, S G, Fearon, D T
Ligation of membrane IgM on B lymphocytes causes activation of a protein-tyrosine kinase(s) (PTK) and of phospholipase C (PLC). To determine whether these are elements of a common signal-transduction...
Crooks, M E, Littman, D R, Carter, R H, Fearon, D T, Weiss, A, Stein, P H
T-cell activation involves two distinct signal transduction pathways. Antigen-specific signaling events are initiated by T-cell receptor recognition of cognate peptide presented by major...
Epstein-Barr virus (EBV) infection of murine L cells expressing recombinant human EBV/C3d receptor.
Ahearn, J M, Hayward, S D, Hickey, J C, Fearon, D T
The normal host range of Epstein-Barr virus (EBV) is limited to primate B lymphocytes and certain epithelial cells that express the C3d/EBV receptor [complement receptor 2 (CR2, CD21)]. In the...
Identification of a 145,000 Mr membrane protein as the C3d receptor (CR2) of human B lymphocytes.
Weis, J J, Tedder, T F, Fearon, D T
The C3d receptor (CR2) of human B lymphocytes mediates the binding to these cells of immune complexes that have activated the complement system and bear the fragments of C3, iC3b, C3d,g, and C3d. A...
Epstein-Barr virus receptor of human B lymphocytes is the C3d receptor CR2.
Fingeroth, J D, Weis, J J, Tedder, T F, Strominger, J L, Biro, P A, Fearon, D T
Identity of the Epstein-Barr virus (EBV) receptor with the complement receptor type 2 (CR2) was established in three sets of experiments using the monoclonal antibodies, HB-5 and anti-B2, which...
Petty, H R, Smith, L M, Fearon, D T, McConnell, H M
Fluorescence microscopy and fluorescence redistribution after pattern photobleaching have been used to measure the distribution and motion of a number of fluorescent molecules bound to the plasma...
Kazatchkine, M D, Fearon, D T, Appay, M D, Mandet, C, Bariety, J
The presence and distribution of C3b receptors in normal human kidneys and in biopsies from 75 patients with renal disease were investigated by immunohistochemical techniques using monospecific...
Weis, J J, Fearon, D T, Klickstein, L B, Wong, W W, Richards, S A, ...
Human complement receptor type 2 (CR2) is the B-lymphocyte receptor both for the C3d fragment of the third component of complement and for the Epstein-Barr virus. Amino acid sequence analysis of...
Identification of a partial cDNA clone for the human receptor for complement fragments C3b/C4b.
Wong, W W, Klickstein, L B, Smith, J A, Weis, J H, Fearon, D T
Redundant oligonucleotides were synthesized based on amino acid sequences of tryptic peptides from the purified receptor for human complement fragments C3b/C4b (CR1). These probes were used to screen...
Czop, J K, Fearon, D T, Austen, K F
Monolayers of human peripheral blood monocytes in the absence of exogenous proteins ingest a variety of natural particulate activators of the human alternative complement pathway. Sheep erythrocytes,...
Wilson, J G, Jack, R M, Wong, W W, Schur, P H, Fearon, D T
A 29-yr-old woman with systemic lupus erythematosus (SLE) was found to have no detectable C3b/C4b receptors (CR1) on her erythrocytes (E) when they were assayed by the binding of rabbit polyclonal...
Activation of the alternative complement pathway due to resistance of zymosan-bound.
The surface of zymosan (Zy), by affording a protected microenvironment for C3b and the amplification convertase stabilized by properdin, P,C3b,Bb, shifts the alternative complement pathway from slow...
Control of the amplification convertase of complement by the plasma protein beta1H.
Weiler, J M, Daha, M R, Austen, K F, Fearon, D T
An inhibitory activity for an erythrocyte in termediate bearing the properdin (P)-stabilized amplification C3 convertase, PC3bBb, was recognized in whole normal human serum and separated from C3b...
Properdin: initiation of alternative complement pathway.
Activation of the classical complement (C) system involves conversion of C1 to its active state with subsequent cleavage of C4 and -d C2 so as to form the classical C3 convertase, C42 (a bar...
Genetic regulation of a structural polymorphism of human C3b receptor.
Wong, W W, Wilson, J G, Fearon, D T
Two forms of the human C3b receptor (C3bR), which have relative molecular weights (Mr) of 250,000 and 260,000 and are designated F and S, respectively, have been identified in specific...
Dal Porto, J, Johansen, T E, Catipović, B, Parfiit, D J, Tuveson, D, Gether, U, ...
Genetically engineered or chemically purified soluble monovalent major histocompatibility complex (MHC) molecules, which have previously been used to study T cells, have not blocked cytotoxic T-cell...
Tyrosine phosphorylation of phospholipase C induced by membrane immunoglobulin in B lymphocytes.
Carter, R H, Park, D J, Rhee, S G, Fearon, D T
Ligation of membrane IgM on B lymphocytes causes activation of a protein-tyrosine kinase(s) (PTK) and of phospholipase C (PLC). To determine whether these are elements of a common signal-transduction...
Crooks, M E, Littman, D R, Carter, R H, Fearon, D T, Weiss, A, Stein, P H
T-cell activation involves two distinct signal transduction pathways. Antigen-specific signaling events are initiated by T-cell receptor recognition of cognate peptide presented by major...
Epstein-Barr virus (EBV) infection of murine L cells expressing recombinant human EBV/C3d receptor.
Ahearn, J M, Hayward, S D, Hickey, J C, Fearon, D T
The normal host range of Epstein-Barr virus (EBV) is limited to primate B lymphocytes and certain epithelial cells that express the C3d/EBV receptor [complement receptor 2 (CR2, CD21)]. In the...
Identification of a 145,000 Mr membrane protein as the C3d receptor (CR2) of human B lymphocytes.
Weis, J J, Tedder, T F, Fearon, D T
The C3d receptor (CR2) of human B lymphocytes mediates the binding to these cells of immune complexes that have activated the complement system and bear the fragments of C3, iC3b, C3d,g, and C3d. A...
Epstein-Barr virus receptor of human B lymphocytes is the C3d receptor CR2.
Fingeroth, J D, Weis, J J, Tedder, T F, Strominger, J L, Biro, P A, Fearon, D T
Identity of the Epstein-Barr virus (EBV) receptor with the complement receptor type 2 (CR2) was established in three sets of experiments using the monoclonal antibodies, HB-5 and anti-B2, which...
Petty, H R, Smith, L M, Fearon, D T, McConnell, H M
Fluorescence microscopy and fluorescence redistribution after pattern photobleaching have been used to measure the distribution and motion of a number of fluorescent molecules bound to the plasma...
Kazatchkine, M D, Fearon, D T, Appay, M D, Mandet, C, Bariety, J
The presence and distribution of C3b receptors in normal human kidneys and in biopsies from 75 patients with renal disease were investigated by immunohistochemical techniques using monospecific...
Weis, J J, Fearon, D T, Klickstein, L B, Wong, W W, Richards, S A, ...
Human complement receptor type 2 (CR2) is the B-lymphocyte receptor both for the C3d fragment of the third component of complement and for the Epstein-Barr virus. Amino acid sequence analysis of...
Identification of a partial cDNA clone for the human receptor for complement fragments C3b/C4b.
Wong, W W, Klickstein, L B, Smith, J A, Weis, J H, Fearon, D T
Redundant oligonucleotides were synthesized based on amino acid sequences of tryptic peptides from the purified receptor for human complement fragments C3b/C4b (CR1). These probes were used to screen...
Czop, J K, Fearon, D T, Austen, K F
Monolayers of human peripheral blood monocytes in the absence of exogenous proteins ingest a variety of natural particulate activators of the human alternative complement pathway. Sheep erythrocytes,...
Wilson, J G, Jack, R M, Wong, W W, Schur, P H, Fearon, D T
A 29-yr-old woman with systemic lupus erythematosus (SLE) was found to have no detectable C3b/C4b receptors (CR1) on her erythrocytes (E) when they were assayed by the binding of rabbit polyclonal...
Activation of the alternative complement pathway due to resistance of zymosan-bound.
The surface of zymosan (Zy), by affording a protected microenvironment for C3b and the amplification convertase stabilized by properdin, P,C3b,Bb, shifts the alternative complement pathway from slow...
Control of the amplification convertase of complement by the plasma protein beta1H.
Weiler, J M, Daha, M R, Austen, K F, Fearon, D T
An inhibitory activity for an erythrocyte in termediate bearing the properdin (P)-stabilized amplification C3 convertase, PC3bBb, was recognized in whole normal human serum and separated from C3b...
Properdin: initiation of alternative complement pathway.
Activation of the classical complement (C) system involves conversion of C1 to its active state with subsequent cleavage of C4 and -d C2 so as to form the classical C3 convertase, C42 (a bar...
Genetic regulation of a structural polymorphism of human C3b receptor.
Wong, W W, Wilson, J G, Fearon, D T
Two forms of the human C3b receptor (C3bR), which have relative molecular weights (Mr) of 250,000 and 260,000 and are designated F and S, respectively, have been identified in specific...
Daha, M R, Fearon, D T, Austen, K F
C3 nephritic factor (C3NeF) interacts with native C3 and B in the absence of D to generate a C3 convertase containing an uncleaved form of B. Dose response studies with C3NeF and B, respectively,...
Lee, J, Hakim, R M, Fearon, D T
Activation of complement and the relative number of C3b receptors expressed by neutrophils was assessed in patients undergoing haemodialysis with new and reused cellulosic membranes, and with...
Anti-inflammatory and immunosuppressive effects of recombinant soluble complement receptors.
CR1 and CR2 have served as unusual probes for the analysis of the two major functions of the immune system involving inflammation and the immune response, respectively. CR1, or some construct...