Damien R. Drew

Truncation of Plasmodium berghei merozoite surface protein 8 does not affect in vivo blood-stage development (2008)

Drew, Damien R., Chesson, Joanne M., Beeson, James G., Crabb, Brendan S.

Merozoite surface protein 8 (MSP8) has shown promise as a vaccine candidate in the Plasmodium yoelii rodent malaria model and has a proposed role in merozoite invasion of erythrocytes. However, the...

Transmission stage investment of malaria parasites in response to in-host competition (2007)

Wargo, Andrew R, De Roode, Jacobus C, Huijben, Silvie, Drew, Damien R, Read, Andrew F

Conspecific competition occurs in a multitude of organisms, particularly in parasites, where several clones are commonly sharing limited resources inside their host. In theory, increased or decreased...

Successful Boosting of a DNA Measles Immunization with an Oral Plant-Derived Measles Virus Vaccine

Webster, Diane E., Cooney, Michelle L., Huang, Zhongjun, Drew, Damien R., Ramshaw, Ian A., Dry, Ian B., ...

Despite eradication attempts, measles remains a global health concern. Here we report results that demonstrate that a single-dose DNA immunization followed by multiple boosters, delivered orally as a...

Plasmodium falciparum Merozoite Surface Protein 8 Is a Ring-Stage Membrane Protein That Localizes to the Parasitophorous Vacuole of Infected Erythrocytes

Drew, Damien R., Sanders, Paul R., Crabb, Brendan S.

To date, the following seven glycosylphosphatidylinositol (GPI)-anchored merozoite antigens have been described in Plasmodium falciparum: merozoite-associated surface protein 1 (MSP-1), MSP-2, MSP-4,...

A Set of Glycosylphosphatidyl Inositol-Anchored Membrane Proteins of Plasmodium falciparum Is Refractory to Genetic Deletion

Sanders, Paul R., Kats, Lev M., Drew, Damien R., O'Donnell, Rebecca A., O'Neill, Matthew, Maier, Alexander G., ...

Targeted gene disruption has proved to be a powerful approach for studying the function of important ligands involved in erythrocyte invasion by the extracellular merozoite form of the human malaria...

Successful Boosting of a DNA Measles Immunization with an Oral Plant-Derived Measles Virus Vaccine

Webster, Diane E., Cooney, Michelle L., Huang, Zhongjun, Drew, Damien R., Ramshaw, Ian A., Dry, Ian B., ...

Despite eradication attempts, measles remains a global health concern. Here we report results that demonstrate that a single-dose DNA immunization followed by multiple boosters, delivered orally as a...

Plasmodium falciparum Merozoite Surface Protein 8 Is a Ring-Stage Membrane Protein That Localizes to the Parasitophorous Vacuole of Infected Erythrocytes

Drew, Damien R., Sanders, Paul R., Crabb, Brendan S.

To date, the following seven glycosylphosphatidylinositol (GPI)-anchored merozoite antigens have been described in Plasmodium falciparum: merozoite-associated surface protein 1 (MSP-1), MSP-2, MSP-4,...

A Set of Glycosylphosphatidyl Inositol-Anchored Membrane Proteins of Plasmodium falciparum Is Refractory to Genetic Deletion

Sanders, Paul R., Kats, Lev M., Drew, Damien R., O'Donnell, Rebecca A., O'Neill, Matthew, Maier, Alexander G., ...

Targeted gene disruption has proved to be a powerful approach for studying the function of important ligands involved in erythrocyte invasion by the extracellular merozoite form of the human malaria...

A New Rodent Model to Assess Blood Stage Immunity to the Plasmodium falciparum Antigen Merozoite Surface Protein 119 Reveals a Protective Role for Invasion Inhibitory Antibodies

O'Donnell, Rebecca A., Drew, Damien R., Thomson, Russell, Speed, Terence P., Crabb, Brendan S.

Antibodies capable of inhibiting the invasion of Plasmodium merozoites into erythrocytes are present in individuals that are clinically immune to the malaria parasite. Those targeting the 19-kD...

Transmission stage investment of malaria parasites in response to in-host competition

Wargo, Andrew R, De Roode, Jacobus C, Huijben, Silvie, Drew, Damien R, Read, Andrew F

Conspecific competition occurs in a multitude of organisms, particularly in parasites, where several clones are commonly sharing limited resources inside their host. In theory, increased or decreased...