Dan Rujescu

Common variants conferring risk of schizophrenia (2009)

Stefansson, Hreinn, Ophoff, Roel A, Steinberg, Stacy, Andreassen, Ole A, Cichon, Sven, Rujescu, Dan, ...

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Disruption of the neurexin 1 gene is associated with schizophrenia (2009)

Rujescu, Dan, Ingason, Andres, Cichon, Sven, Pietiläinen, Olli P H, Barnes, Michael R, Toulopoulou, Timothea, ...

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Disruption of the neurexin 1 gene is associated with schizophrenia (2009)

Rujescu, Dan, Ingason, Andres, Cichon, Sven, Pietiläinen, Olli P.H., Barnes, Michael R., Toulopoulou, Timothea, ...

Deletions within the neurexin 1 gene (NRXN1; 2p16.3) are associated with autism and have also been reported in two families with schizophrenia. We examined NRXN1, and the closely related NRXN2 and...

Large recurrent microdeletions associated with schizophrenia (2008)

Stefansson, Hreinn, Rujescu, Dan, Cichon, Sven, Pietiläinen, Olli P H, Ingason, Andres, Steinberg, Stacy, ...

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Identification of loci associated with schizophrenia by genome-wide association and follow-up (2008)

Donovan, Michael C., Craddock, Nicholas, Norton, Nadine, Williams, Hywel, Peirce, Timothy, Moskvina, Valentina, ...

We carried out a genome-wide association study of schizophrenia (479 cases, 2,937 controls) and tested loci with P < 10-5 in up to 16,726 additional subjects. Of 12 loci followed up, 3 had strong...

Strong evidence that GNB1L is associated with schizophrenia (2007)

Williams, Nigel Melville, Glaser, Beate, Norton, Nadine, Williams, Hywel John, Pierce, Timothy, Moskvina, Valentina, ...

Evidence that a gene or genes on chromosome 22 is involved in susceptibility to schizophrenia comes from two sources: the increased incidence of schizophrenia in individuals with 22q11 deletion...

Detection of TOAD-64 in adult rat brain as revealed by two- dimensional protein gel electrophoresis followed by MALDI mass spectrometry - Possible modulatory effect of chronic haloperidol treatment (2002)

Dahmen,Norbert, Jungblut,Peter R., Fischer,Viola, Schrank,Martina, Reuss,Stefan, Rujescu,Dan, ...

The molecular mechanisms by which antipsychotic effects are achieved remain largely elusive. Possible mechanisms include the modulation of nerve cell gene expression. The antipsychotic drug...

Association analysis between variants of the interleukin-1β and the interleukin-1 receptor antagonist gene and antidepressant treatment response in major depression

Tadić, André, Rujescu, Dan, Müller, Matthias J, Kohnen, Ralf, Stassen, Hans H., Szegedi, Armin, ...

This study investigated the possible association of the interleukin-1 beta (IL-1β) C-511T promoter polymorphism and the interleukin-1 receptor antagonist (IL-1Ra) (86bp)n variable number of tandem...

A Genome-Wide Investigation of SNPs and CNVs in Schizophrenia

Need, Anna C., Ge, Dongliang, Weale, Michael E., Maia, Jessica, Feng, Sheng, Heinzen, Erin L., ...

We report a genome-wide assessment of single nucleotide polymorphisms (SNPs) and copy number variants (CNVs) in schizophrenia. We investigated SNPs using 871 patients and 863 controls, following up...