Dana R. Smulski

Global Impact of sdiA Amplification Revealed by Comprehensive Gene Expression Profiling of Escherichia coli

Wei, Yan, Lee, Jian-Ming, Smulski, Dana R., LaRossa, Robert A.

In Escherichia coli the amplification of sdiA, a positive activator of ftsQAZ, genes that are essential for septation, results in mitomycin C resistance. To help us understand this resistance...

DNA Microarray-Mediated Transcriptional Profiling of the Escherichia coli Response to Hydrogen Peroxide

Zheng, Ming, Wang, Xunde, Templeton, Lori J., Smulski, Dana R., LaRossa, Robert A., Storz, Gisela

The genome-wide transcription profile of Escherichia coli cells treated with hydrogen peroxide was examined with a DNA microarray composed of 4,169 E. coli open reading frames. By measuring gene...

Combined, Functional Genomic-Biochemical Approach to Intermediary Metabolism: Interaction of Acivicin, a Glutamine Amidotransferase Inhibitor, with Escherichia coli K-12

Smulski, Dana R., Huang, Lixuan L., McCluskey, Michael P., Reeve, Mary Jane Gladnick, Vollmer, Amy C., Van Dyk, Tina K., ...

Acivicin, a modified amino acid natural product, is a glutamine analog. Thus, it might interfere with metabolism by hindering glutamine transport, formation, or usage in processes such as...

Interfering with Different Steps of Protein Synthesis Explored by Transcriptional Profiling of Escherichia coli K-12†

Sabina, Jeffrey, Dover, Nir, Templeton, Lori J., Smulski, Dana R., Söll, Dieter, LaRossa, Robert A.

Escherichia coli responses to four inhibitors that interfere with translation were monitored at the transcriptional level. A DNA microarray method provided a comprehensive view of changes in mRNA...

Global Impact of sdiA Amplification Revealed by Comprehensive Gene Expression Profiling of Escherichia coli

Wei, Yan, Lee, Jian-Ming, Smulski, Dana R., LaRossa, Robert A.

In Escherichia coli the amplification of sdiA, a positive activator of ftsQAZ, genes that are essential for septation, results in mitomycin C resistance. To help us understand this resistance...

DNA Microarray-Mediated Transcriptional Profiling of the Escherichia coli Response to Hydrogen Peroxide

Zheng, Ming, Wang, Xunde, Templeton, Lori J., Smulski, Dana R., LaRossa, Robert A., Storz, Gisela

The genome-wide transcription profile of Escherichia coli cells treated with hydrogen peroxide was examined with a DNA microarray composed of 4,169 E. coli open reading frames. By measuring gene...

Combined, Functional Genomic-Biochemical Approach to Intermediary Metabolism: Interaction of Acivicin, a Glutamine Amidotransferase Inhibitor, with Escherichia coli K-12

Smulski, Dana R., Huang, Lixuan L., McCluskey, Michael P., Reeve, Mary Jane Gladnick, Vollmer, Amy C., Van Dyk, Tina K., ...

Acivicin, a modified amino acid natural product, is a glutamine analog. Thus, it might interfere with metabolism by hindering glutamine transport, formation, or usage in processes such as...

Interfering with Different Steps of Protein Synthesis Explored by Transcriptional Profiling of Escherichia coli K-12†

Sabina, Jeffrey, Dover, Nir, Templeton, Lori J., Smulski, Dana R., Söll, Dieter, LaRossa, Robert A.

Escherichia coli responses to four inhibitors that interfere with translation were monitored at the transcriptional level. A DNA microarray method provided a comprehensive view of changes in mRNA...