Saw, Jimmy H, Mountain, Bruce W, Feng, Lu, Omelchenko, Marina V, Hou, Shaobin, Saito, Jennifer A, ...
Abstract Background Gram-positive bacteria of the genus Anoxybacillus have been found in diverse thermophilic habitats, such as geothermal hot springs and manure, and in processed foods such as...
Yu, Zhong, Genest, Paul-André, Ter Riet, Bas, Sweeney, Kate, DiPaolo, Courtney, Kieft, Rudo, ...
Trypanosomatids contain an unusual DNA base J (β-d-glucosylhydroxymethyluracil), which replaces a fraction of thymine in telomeric and other DNA repeats. To determine the function of base J, we have...
Davies, Lyndsay, Anderson, Ian P., Turner, Philip C., Shirras, Alan D., Rees, Huw H., Rigden, Daniel J.
The insect enzyme ecdysteroid phosphate phosphatase (EPP) mobilizes active ecdysteroids from an inactive phosphorylated pool. Previously assigned to a novel class, it is shown here that it resides in...
Yu, Zhong, Genest, Paul-Andre, Ter Riet, Bas, Sweeney, Kate, DiPaolo, Courtney, Kieft, Rudo, ...
© 2007 The Author et al. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/ by-nc/2.0/uk/)...
Rigden, Daniel J., Botzki, Alexander, Nukui, Masatoshi, Mewbourne, R. Brandon, Lamani, Ejvis, Braun, Stephan, ...
The bacterial hyaluronan lyases (Hyals) that degrade hyaluronan, an important component of the extracellular matrix, are involved in microbial spread. Inhibitors of these enzymes are essential in...
Rigden, Daniel J., Botzki, Alexander, Nukui, Masatoshi, Mewbourne, R. Brandon, Lamani, Ejvis, Braun, Stephan, ...
The bacterial hyaluronan lyases (Hyal) that degrade hyaluronan, an important component of the extracellular matrix, are involved in microbial spread. Inhibitors of these enzymes are essential in...
Rigden, Daniel J., Botzki, Alexander, Nukui, Masatoshi, Mewbourne, R. Brandon, Lamani, Ejvis, Braun, Stephan, ...
The bacterial hyaluronan lyases (Hyals) that degrade hyaluronan, an important component of the extracellular matrix, are involved in microbial spread. Inhibitors of these enzymes are essential in...
Rigden, Daniel J., Botzki, Alexander, Nukui, Masatoshi, Mewbourne, R. Brandon, Lamani, Ejvis, Braun, Stephan, ...
The bacterial hyaluronan lyases (Hyal) that degrade hyaluronan, an important component of the extracellular matrix, are involved in microbial spread. Inhibitors of these enzymes are essential in...
Bourgis, Fabienne, Botha, Fredrik C., Mani, Srikrishnan, Hiten, Fletcher N., Rigden, Daniel J., Verbruggen, Nathalie
An Arabidopsis thaliana cDNA (At-74) has been isolated that encoded an uncharacterized protein showing homology with members of the d-PGMase superfamily: cofactor-dependent phosphoglycerate mutases...
Bourgis, Fabienne, Botha, Fredrik C., Mani, Srikrishnan, Hiten, Fletcher N., Rigden, Daniel J., Verbruggen, Nathalie
An Arabidopsis thaliana cDNA (At-74) has been isolated that encoded an uncharacterized protein showing homology with members of the d-PGMase superfamily: cofactor-dependent phosphoglycerate mutases...
Bourgis, Fabienne, Botha, Fredrik C., Mani, Srikrishnan, Hiten, Fletcher N., Rigden, Daniel J., Verbruggen, Nathalie
An Arabidopsis thaliana cDNA (At-74) has been isolated that encoded an uncharacterized protein showing homology with members of the d-PGMase superfamily: cofactor-dependent phosphoglycerate mutases...
Botzki, Alexander, Rigden, Daniel J., Braun, Stephan, Nukui, Masatoshi, Salmen, Sunnhild, Hoechstetter, Julia, ...
Hyaluronidases are enzymes that degrade hyaluronan, an important component of the extracellular matrix. The mammalian hyaluronidases are considered to be involved in many (patho)physiological...
Archaea recruited D-Tyr-tRNATyr deacylase for editing in Thr-tRNA synthetase (2004)
Aminoacyl–tRNA synthetases (AARSs) are key players in the maintenance of the genetic code through correct pairing of amino acids with their cognate tRNA molecules. To this end, some AARSs, as well...
Archaea recruited D-Tyr-tRNATyr deacylase for editing in Thr-tRNA synthetase (2004)
Aminoacyl–tRNA synthetases (AARSs) are key players in the maintenance of the genetic code through correct pairing of amino acids with their cognate tRNA molecules. To this end, some AARSs, as well...
Octavio L. Franco, Daniel J. Rigden
Glycosyltransferases (GTs) are diverse enzymes organized into 65 families. X-ray crystallography and in silico studies have shown many of these to belong to two structural superfamilies: GT-A and...
Franco, Octávio L., Rigden, Daniel J.
Glycosyltransferases (GTs) are diverse enzymes organized into 65 families. X-ray crystallography and in silico studies have shown many of these to belong to two structural superfamilies - GT-A and...
Franco, Octávio L., Rigden, Daniel J.
Glycosyltransferases (GTs) are diverse enzymes organized into 65 families. X-ray crystallography and in silico studies have shown many of these to belong to two structural superfamilies: GT-A and...
Franco, Octávio L., Rigden, Daniel J.
Glycosyltransferases (GTs) are diverse enzymes organized into 65 families. X-ray crystallography and in silico studies have shown many of these to belong to two structural superfamilies - GT-A and...
Rigden, Daniel J., Mosolov, Vladimir V., Galperin, Michael Y.
The recently described inhibitor of cysteine proteinases from Trypanosoma cruzi, chagasin, was found to have close homologs in several eukaryotes, bacteria and archaea, the first protein inhibitors...
Current methods for identification of domains within protein sequences require either structural information or the identification of homologous domain sequences in different sequence contexts....
Rigden, Daniel J., Setlow, Peter, Setlow, Barbara, Bagyan, Irina, Stein, Richard A., Jedrzejas, Mark J.
The prfA gene product of Gram-positive bacteria is unusual in being implicated in several cellular processes; cell wall synthesis, chromosome segregation, and DNA recombination and repair. However,...
Rigden, Daniel J., Bagyan, Irina, Lamani, Ejvis, Setlow, Peter, Jedrzejas, Mark J.
The distribution of phosphoglycerate mutase (PGM) activity in bacteria is complex, with some organisms possessing both a cofactor-dependent and a cofactor-independent PGM and others having only one...
Caldas, Cristina, Rigden, Daniel J., Neschich, Goran, Moro, Ana Maria, Brígido, Marcelo M.
The 6.7 murine monoclonal antibody (mAb) recognizes the human CD18 antigen and is therefore of interest as an anti-inflammatory agent. The 6.7 heavy variable chain (VH) was humanized using the...
Plant-like traits associated with metabolism of Trypanosoma parasites
Hannaert, Véronique, Saavedra, Emma, Duffieux, Francis, Szikora, Jean-Pierre, Rigden, Daniel J., Michels, Paul A. M., ...
Trypanosomatid parasites cause serious diseases among humans, livestock, and plants. They belong to the order of the Kinetoplastida and form, together with the Euglenida, the phylum Euglenozoa....
Archaea recruited d-Tyr-tRNATyr deacylase for editing in Thr–tRNA synthetase
Aminoacyl–tRNA synthetases (AARSs) are key players in the maintenance of the genetic code through correct pairing of amino acids with their cognate tRNA molecules. To this end, some AARSs, as well...
Plant-like traits associated with metabolism of Trypanosoma parasites
Hannaert, Véronique, Saavedra, Emma, Duffieux, Francis, Szikora, Jean-Pierre, Rigden, Daniel J., Michels, Paul A. M., ...
Trypanosomatid parasites cause serious diseases among humans, livestock, and plants. They belong to the order of the Kinetoplastida and form, together with the Euglenida, the phylum Euglenozoa....
Archaea recruited d-Tyr-tRNATyr deacylase for editing in Thr–tRNA synthetase
Aminoacyl–tRNA synthetases (AARSs) are key players in the maintenance of the genetic code through correct pairing of amino acids with their cognate tRNA molecules. To this end, some AARSs, as well...
The protein that binds to DNA base J in trypanosomatids has features of a thymidine hydroxylase
Yu, Zhong, Genest, Paul-André, Ter Riet, Bas, Sweeney, Kate, DiPaolo, Courtney, Kieft, Rudo, ...
Trypanosomatids contain an unusual DNA base J (β-d-glucosylhydroxymethyluracil), which replaces a fraction of thymine in telomeric and other DNA repeats. To determine the function of base J, we have...
Romanyuk, Nataliya D., Rigden, Daniel J., Vatamaniuk, Olena K., Lang, Albert, Cahoon, Rebecca E., Jez, Joseph M., ...
Phytochelatin (PC) synthases are γ-glutamylcysteine (γ-Glu-Cys) dipeptidyl transpeptidases that catalyze the synthesis of heavy metal-binding PCs, (γ-Glu-Cys)nGly polymers, from glutathione (GSH)...
Rigden, Daniel J., Bagyan, Irina, Lamani, Ejvis, Setlow, Peter, Jedrzejas, Mark J.
The distribution of phosphoglycerate mutase (PGM) activity in bacteria is complex, with some organisms possessing both a cofactor-dependent and a cofactor-independent PGM and others having only one...
Rigden, Daniel J., Mosolov, Vladimir V., Galperin, Michael Y.
The recently described inhibitor of cysteine proteinases from Trypanosoma cruzi, chagasin, was found to have close homologs in several eukaryotes, bacteria and archaea, the first protein inhibitors...
PrfA protein of Bacillus species: Prediction and demonstration of endonuclease activity on DNA
Rigden, Daniel J., Setlow, Peter, Setlow, Barbara, Bagyan, Irina, Stein, Richard A., Jedrzejas, Mark J.
The prfA gene product of Gram-positive bacteria is unusual in being implicated in several cellular processes; cell wall synthesis, chromosome segregation, and DNA recombination and repair. However,...
Saw, Jimmy H, Mountain, Bruce W, Feng, Lu, Omelchenko, Marina V, Hou, Shaobin, Saito, Jennifer A, ...
Sequencing of the complete genome of Anoxybacillus flavithermus reveals enzymes that are required for silica adaptation and biofilm formation.
Rigden, Daniel J., Galperin, Michael Y.
Sporulation in low-G+C gram-positive bacteria (Firmicutes) is an important survival mechanism that involves up to 150 genes, acting in a highly regulated manner. Many sporulation genes have close...