A novel and universal method for microRNA RT-qPCR data normalization (2009)
Mestdagh, Pieter, Van Vlierberghe, Pieter, De Weer, An, Muth, Daniel, Westermann, Frank, Speleman, Frank, ...
Abstract Gene expression analysis of microRNA molecules is becoming increasingly important. In this study we assess the use of the mean expression value of all expressed microRNAs in a given sample...
Westermann, Frank, Muth, Daniel, Benner, Axel, Bauer, Tobias, Henrich, Kai-Oliver, Oberthuer, André, ...
Abstract Background Amplified MYCN oncogene resulting in deregulated MYCN transcriptional activity is observed in 20% of neuroblastomas and identifies a highly aggressive subtype. In MYCN single-copy...
Cathepsin D protects human neuroblastoma cells from doxorubicin-induced cell death (2008)
Sagulenko, Vitalia, Muth, Daniel, Sagulenko, Evgeny, Paffhausen, Tobias, Schwab, Manfred, Westermann, Frank
High incidence of chemotherapy resistance is the primary cause of treatment failure in a subset of neuroblastomas with amplified MYCN. We have reported previously that ectopic MYCN expression...
A novel and universal method for microRNA RT-qPCR data normalization
Mestdagh, Pieter, Van Vlierberghe, Pieter, De Weer, An, Muth, Daniel, Westermann, Frank, Speleman, Frank, ...
The mean expression value: a new method for accurate and reliable normalization of microRNA expression data from RT-qPCR experiments.
Westermann, Frank, Muth, Daniel, Benner, Axel, Bauer, Tobias, Henrich, Kai-Oliver, Oberthuer, André, ...
Differences in MYCN/c-MYC target gene expression are associated with distinct neuroblastoma subtypes and clinical outcome.