Daniel O. Sánchez

Trypanosoma cruzi surface mucin TcMuc-e2 expressed on higher eukaryotic cells induces human T cell anergy, which is reversible (2002)

Argibay, Pablo F., Di Noia, Javier M., Hidalgo, Alejandra, Mocetti, Esteban, Barbich, Mariana, Lorenti, Alicia S., ...

Chagas’ disease is a chronic, debilitating, multisystemic disorder that affects millions of people in Latin America. The protozoan parasite Trypanosoma cruzi, the etiological agent of Chagas’...

Gene Discovery through Genomic Sequencing of Brucella abortus

Sánchez, Daniel O., Zandomeni, Ruben O., Cravero, Silvio, Verdún, Ramiro E., Pierrou, Ester, Faccio, Paula, ...

Brucella abortus is the etiological agent of brucellosis, a disease that affects bovines and human. We generated DNA random sequences from the genome of B. abortus strain 2308 in order to...

A Homologue of an Operon Required for DNA Transfer in Agrobacterium Is Required in Brucella abortus for Virulence and Intracellular Multiplication

Sieira, Rodrigo, Comerci, Diego J., Sánchez, Daniel O., Ugalde, Rodolfo A.

As part of a Brucella abortus 2308 genome project carried out in our laboratory, we identified, cloned, and sequenced a genomic DNA fragment containing a locus (virB) highly homologous to bacterial...

Gene Discovery in the Freshwater Fish Parasite Trypanosoma carassii: Identification of trans-Sialidase-Like and Mucin-Like Genes

Agüero, Fernán, Campo, Vanina, Cremona, Laura, Jäger, Adriana, Di Noia, Javier M., Overath, Peter, ...

A total of 1,921 expressed sequence tags (ESTs) were obtained from bloodstream trypomastigotes of Trypanosoma carassii, a parasite of economic importance due to its high prevalence in fish farms....

gp63 Homologues in Trypanosoma cruzi: Surface Antigens with Metalloprotease Activity and a Possible Role in Host Cell Infection

Cuevas, Ileana C., Cazzulo, Juan J., Sánchez, Daniel O.

gp63 is a highly abundant glycosylphosphatidylinositol (GPI)-anchored membrane protein expressed predominantly in the promastigote but also in the amastigote stage of Leishmania species. In...

A Random Sequencing Approach for the Analysis of the Trypanosoma cruzi Genome: General Structure, Large Gene and Repetitive DNA Families, and Gene Discovery

Agüero, Fernán, Verdún, Ramiro E., Frasch, Alberto Carlos C., Sánchez, Daniel O.

A random sequence survey of the genome of Trypanosoma cruzi, the agent of Chagas disease, was performed and 11,459 genomic sequences were obtained, resulting in ∼4.3 Mb of readable sequences or...

Characterization of Farnesylated Protein Tyrosine Phosphatase TcPRL-1 from Trypanosoma cruzi†

Cuevas, Ileana C., Rohloff, Peter, Sánchez, Daniel O., Docampo, Roberto

Protein tyrosine kinases and phosphatases play important roles in the regulation of cell growth, development, and differentiation. We report here the identification in Trypanosoma cruzi of a gene...

Gene Discovery through Genomic Sequencing of Brucella abortus

Sánchez, Daniel O., Zandomeni, Ruben O., Cravero, Silvio, Verdún, Ramiro E., Pierrou, Ester, Faccio, Paula, ...

Brucella abortus is the etiological agent of brucellosis, a disease that affects bovines and human. We generated DNA random sequences from the genome of B. abortus strain 2308 in order to...

A Homologue of an Operon Required for DNA Transfer in Agrobacterium Is Required in Brucella abortus for Virulence and Intracellular Multiplication

Sieira, Rodrigo, Comerci, Diego J., Sánchez, Daniel O., Ugalde, Rodolfo A.

As part of a Brucella abortus 2308 genome project carried out in our laboratory, we identified, cloned, and sequenced a genomic DNA fragment containing a locus (virB) highly homologous to bacterial...

Gene Discovery in the Freshwater Fish Parasite Trypanosoma carassii: Identification of trans-Sialidase-Like and Mucin-Like Genes

Agüero, Fernán, Campo, Vanina, Cremona, Laura, Jäger, Adriana, Di Noia, Javier M., Overath, Peter, ...

A total of 1,921 expressed sequence tags (ESTs) were obtained from bloodstream trypomastigotes of Trypanosoma carassii, a parasite of economic importance due to its high prevalence in fish farms....

gp63 Homologues in Trypanosoma cruzi: Surface Antigens with Metalloprotease Activity and a Possible Role in Host Cell Infection

Cuevas, Ileana C., Cazzulo, Juan J., Sánchez, Daniel O.

gp63 is a highly abundant glycosylphosphatidylinositol (GPI)-anchored membrane protein expressed predominantly in the promastigote but also in the amastigote stage of Leishmania species. In...

A Random Sequencing Approach for the Analysis of the Trypanosoma cruzi Genome: General Structure, Large Gene and Repetitive DNA Families, and Gene Discovery

Agüero, Fernán, Verdún, Ramiro E., Frasch, Alberto Carlos C., Sánchez, Daniel O.

A random sequence survey of the genome of Trypanosoma cruzi, the agent of Chagas disease, was performed and 11,459 genomic sequences were obtained, resulting in ∼4.3 Mb of readable sequences or...

Characterization of Farnesylated Protein Tyrosine Phosphatase TcPRL-1 from Trypanosoma cruzi†

Cuevas, Ileana C., Rohloff, Peter, Sánchez, Daniel O., Docampo, Roberto

Protein tyrosine kinases and phosphatases play important roles in the regulation of cell growth, development, and differentiation. We report here the identification in Trypanosoma cruzi of a gene...