Daniel R. Schoenberg

KSRP-PMR1-exosome association determines parathyroid hormone mRNA levels and stability in transfected cells (2009)

Nechama, Morris, Peng, Yong, Bell, Osnat, Briata, Paola, Gherzi, Roberto, Schoenberg, Daniel R, ...

Abstract Background Parathyroid hormone (PTH) gene expression is regulated post-transcriptionally through the binding of the trans- acting proteins AU rich binding factor 1 (AUF1), Upstream of N- ras...

The cytoskeleton-associated Ena/VASP proteins are unanticipated partners of the PMR1 mRNA endonuclease (2009)

Peng, Yong, Murray, Elizabeth L., Sarkar, Madhubanti, Liu, Xiaoqiang, Schoenberg, Daniel R.

The PMR1 mRNA endonuclease catalyzes the selective decay of a limited number of mRNAs. It participates in multiple complexes, including one containing c-Src, its activating kinase, and one containing...

The poly(A)-limiting element enhances mRNA accumulation by increasing the efficiency of pre-mRNA 3' processing (2005)

PENG, JING, MURRAY, ELIZABETH L., SCHOENBERG, DANIEL R.

The poly(A)-limiting element (PLE) is a conserved sequence originally found in the 3′ UTR of Xenopus albumin mRNA whose presence restricts the length of the poly(A) tail on both pre-mRNA and fully...

mRNA with a (2005)

PENG, JING, SCHOENBERG, DANIEL R.

The poly(A)-limiting element (PLE) is a conserved sequence that restricts the length of the poly(A) tail to

The poly(A)-limiting element enhances mRNA accumulation by increasing the efficiency of pre-mRNA 3' processing (2005)

PENG, JING, MURRAY, ELIZABETH L., SCHOENBERG, DANIEL R.

The poly(A)-limiting element (PLE) is a conserved sequence originally found in the 3′ UTR of Xenopus albumin mRNA whose presence restricts the length of the poly(A) tail on both pre-mRNA and fully...

U2AF modulates poly(A) length control by the poly(A)-limiting element (2003)

Gu, Haidong, Schoenberg, Daniel R.

The poly(A)‐limiting element (PLE) restricts the length of the poly(A) tail to

An endonuclease activity similar to Xenopus PMR1 catalyzes the degradation of normal and nonsense-containing human {beta}-globin mRNA in erythroid cells (2003)

BREMER, KIRSTEN A., STEVENS, AUDREY, SCHOENBERG, DANIEL R.

&bgr;-globin mRNA bearing a nonsense codon is degraded in the cytoplasm of erythroid cells by endonuclease cleavage, preferentially at UG dinucleotides. An endonuclease activity in polysomes of MEL...

Polysomal ribonuclease 1 exists in a latent form on polysomes prior to estrogen activation of mRNA decay (2001)

Cunningham, Kristopher S., Hanson, Mark N., Schoenberg, Daniel R.

Estrogen induces a global change in the translation profile of Xenopus hepatocytes, replacing serum protein synthesis with production of the yolk protein precursor vitellogenin. This is accomplished...

Albumin is encoded by 2 messenger RNAs in Xenopus laevis (1981)

Schoenberg, Daniel R.

A cDNA clone library was prepared from liver poly(A) RNA of nonestrogenized Xenopus laevis. Albumin coding sequences were screened by hybridization to a cDNA prepared from poly(A) RNA enriched by...

The poly(A)-limiting element is a conserved cis-acting sequence that regulates poly(A) tail length on nuclear pre-mRNAs

Gu, Haidong, Das Gupta, Jaydip, Schoenberg, Daniel R.

Most vertebrate mRNAs exit the nucleus with a 200+-residue poly(A) tail and are deadenylated to yield heterogeneous polymers of 50–200 adenosine residues on any given mRNA. We previously reported...

Vigilin binding selectively inhibits cleavage of the vitellogenin mRNA 3′-untranslated region by the mRNA endonuclease polysomal ribonuclease 1

Cunningham, Kristopher S., Dodson, Robin E., Nagel, Maria A., Shapiro, David J., Schoenberg, Daniel R.

In Xenopus, estrogen induces the stabilization of vitellogenin mRNA and the destabilization of albumin mRNA. These processes correlate with increased polysomal activity of a sequence-selective mRNA...

Polysomal ribonuclease 1 exists in a latent form on polysomes prior to estrogen activation of mRNA decay

Cunningham, Kristopher S., Hanson, Mark N., Schoenberg, Daniel R.

Estrogen induces a global change in the translation profile of Xenopus hepatocytes, replacing serum protein synthesis with production of the yolk protein precursor vitellogenin. This is accomplished...

β-Globin mRNA decay in erythroid cells: UG site-preferred endonucleolytic cleavage that is augmented by a premature termination codon

Stevens, Audrey, Wang, Yang, Bremer, Kirsten, Zhang, Jing, Hoepfner, Robert, Antoniou, Michael, ...

Previous work showed that human β-globin mRNAs harboring a premature termination codon are degraded in the erythroid tissues of mice to products that lack sequences from the mRNA 5′ end but...

U2AF modulates poly(A) length control by the poly(A)-limiting element

Gu, Haidong, Schoenberg, Daniel R.

The poly(A)-limiting element (PLE) restricts the length of the poly(A) tail to

Nuclear association states of rat uterine oestrogen receptors as probed by nuclease digestion

Schoenberg, Daniel R., Clark, James H.

The solubilization of oestrogen receptors from uterine nuclei by micrococcal nuclease and deoxyribonuclease I was examined after the injection of oestradiol or Nafoxidine into castrated female rats....

mRNA with a

PENG, JING, SCHOENBERG, DANIEL R.

The poly(A)-limiting element (PLE) is a conserved sequence that restricts the length of the poly(A) tail to

The poly(A)-limiting element enhances mRNA accumulation by increasing the efficiency of pre-mRNA 3′ processing

PENG, JING, MURRAY, ELIZABETH L., SCHOENBERG, DANIEL R.

The poly(A)-limiting element (PLE) is a conserved sequence originally found in the 3′ UTR of Xenopus albumin mRNA whose presence restricts the length of the poly(A) tail on both pre-mRNA and fully...

An endonuclease activity similar to Xenopus PMR1 catalyzes the degradation of normal and nonsense-containing human β-globin mRNA in erythroid cells

BREMER, KIRSTEN A., STEVENS, AUDREY, SCHOENBERG, DANIEL R.

β-globin mRNA bearing a nonsense codon is degraded in the cytoplasm of erythroid cells by endonuclease cleavage, preferentially at UG dinucleotides. An endonuclease activity in polysomes of MEL...

The poly(A)-limiting element is a conserved cis-acting sequence that regulates poly(A) tail length on nuclear pre-mRNAs

Gu, Haidong, Das Gupta, Jaydip, Schoenberg, Daniel R.

Most vertebrate mRNAs exit the nucleus with a 200+-residue poly(A) tail and are deadenylated to yield heterogeneous polymers of 50–200 adenosine residues on any given mRNA. We previously reported...

Vigilin binding selectively inhibits cleavage of the vitellogenin mRNA 3′-untranslated region by the mRNA endonuclease polysomal ribonuclease 1

Cunningham, Kristopher S., Dodson, Robin E., Nagel, Maria A., Shapiro, David J., Schoenberg, Daniel R.

In Xenopus, estrogen induces the stabilization of vitellogenin mRNA and the destabilization of albumin mRNA. These processes correlate with increased polysomal activity of a sequence-selective mRNA...

Polysomal ribonuclease 1 exists in a latent form on polysomes prior to estrogen activation of mRNA decay

Cunningham, Kristopher S., Hanson, Mark N., Schoenberg, Daniel R.

Estrogen induces a global change in the translation profile of Xenopus hepatocytes, replacing serum protein synthesis with production of the yolk protein precursor vitellogenin. This is accomplished...

β-Globin mRNA decay in erythroid cells: UG site-preferred endonucleolytic cleavage that is augmented by a premature termination codon

Stevens, Audrey, Wang, Yang, Bremer, Kirsten, Zhang, Jing, Hoepfner, Robert, Antoniou, Michael, ...

Previous work showed that human β-globin mRNAs harboring a premature termination codon are degraded in the erythroid tissues of mice to products that lack sequences from the mRNA 5′ end but...

U2AF modulates poly(A) length control by the poly(A)-limiting element

Gu, Haidong, Schoenberg, Daniel R.

The poly(A)-limiting element (PLE) restricts the length of the poly(A) tail to

Nuclear association states of rat uterine oestrogen receptors as probed by nuclease digestion

Schoenberg, Daniel R., Clark, James H.

The solubilization of oestrogen receptors from uterine nuclei by micrococcal nuclease and deoxyribonuclease I was examined after the injection of oestradiol or Nafoxidine into castrated female rats....

mRNA with a

PENG, JING, SCHOENBERG, DANIEL R.

The poly(A)-limiting element (PLE) is a conserved sequence that restricts the length of the poly(A) tail to

The poly(A)-limiting element enhances mRNA accumulation by increasing the efficiency of pre-mRNA 3′ processing

PENG, JING, MURRAY, ELIZABETH L., SCHOENBERG, DANIEL R.

The poly(A)-limiting element (PLE) is a conserved sequence originally found in the 3′ UTR of Xenopus albumin mRNA whose presence restricts the length of the poly(A) tail on both pre-mRNA and fully...

An endonuclease activity similar to Xenopus PMR1 catalyzes the degradation of normal and nonsense-containing human β-globin mRNA in erythroid cells

BREMER, KIRSTEN A., STEVENS, AUDREY, SCHOENBERG, DANIEL R.

β-globin mRNA bearing a nonsense codon is degraded in the cytoplasm of erythroid cells by endonuclease cleavage, preferentially at UG dinucleotides. An endonuclease activity in polysomes of MEL...

Polysome-Bound Endonuclease PMR1 Is Targeted to Stress Granules via Stress-Specific Binding to TIA-1▿

Yang, Feng, Peng, Yong, Murray, Elizabeth L., Otsuka, Yuichi, Kedersha, Nancy, Schoenberg, Daniel R.

The generalized process of mRNA decay involves deadenylation followed by release from translating polysomes, decapping, and exonuclease decay of the mRNA body. In contrast the mRNA endonuclease PMR1...

A+U-Rich Instability Elements Differentially Activate 5′-3′ and 3′-5′ mRNA Decay▿

Murray, Elizabeth L., Schoenberg, Daniel R.

The A+U-rich elements (or AREs) are cis-acting sequences that activate rapid mRNA decay, yet the overall polarity of this process is unknown. The current study describes an unbiased approach to this...

A role for the eIF4E-binding protein 4E-T in P-body formation and mRNA decay

Ferraiuolo, Maria A., Basak, Sanjukta, Dostie, Josee, Murray, Elizabeth L., Schoenberg, Daniel R., Sonenberg, Nahum

4E-transporter (4E-T) is one of several proteins that bind the mRNA 5′cap-binding protein, eukaryotic initiation factor 4E (eIF4E), through a conserved binding motif. We previously showed that 4E-T...

The 90-kDa Heat Shock Protein Stabilizes the Polysomal Ribonuclease 1 mRNA Endonuclease to Degradation by the 26S Proteasome

Peng, Yong, Liu, Xiaoqiang, Schoenberg, Daniel R.

The polysomal ribonuclease 1 (PMR1) mRNA endonuclease forms a selective complex with its translating substrate mRNAs where it is activated to initiate mRNA decay. Previous work showed tyrosine...

Common SNP in pre-miR-146a decreases mature miR expression and predisposes to papillary thyroid carcinoma

Jazdzewski, Krystian, Murray, Elizabeth L., Franssila, Kaarle, Jarzab, Barbara, Schoenberg, Daniel R., De La Chapelle, Albert

Although papillary thyroid carcinoma (PTC) displays strong heritability, no predisposing germ-line mutations have been found. We show that a common G/C polymorphism (rs2910164) within the...

The cytoskeleton-associated Ena/VASP proteins are unanticipated partners of the PMR1 mRNA endonuclease

Peng, Yong, Murray, Elizabeth L., Sarkar, Madhubanti, Liu, Xiaoqiang, Schoenberg, Daniel R.

The PMR1 mRNA endonuclease catalyzes the selective decay of a limited number of mRNAs. It participates in multiple complexes, including one containing c-Src, its activating kinase, and one containing...

Identification of a Cytoplasmic Complex That Adds a Cap onto 5′-Monophosphate RNA ▿ §

Otsuka, Yuichi, Kedersha, Nancy L., Schoenberg, Daniel R.

Endonuclease decay of nonsense-containing β-globin mRNA in erythroid cells generates 5′-truncated products that were reported previously to have a cap or caplike structure. We confirmed that this...