Daniela Malide

The Export of Major Histocompatibility Complex Class I Molecules from the Endoplasmic Reticulum of Rat Brown Adipose Cells Is Acutely Stimulated by Insulin

Malide, Daniela, Yewdell, Jonathan W., Bennink, Jack R., Cushman, Samuel W.

Major histocompatibility complex class I (MHC-I) molecules have been implicated in several nonimmunological functions including the regulation and intracellular trafficking of the insulin-responsive...

The Influenza A Virus PB1-F2 Protein Targets the Inner Mitochondrial Membrane via a Predicted Basic Amphipathic Helix That Disrupts Mitochondrial Function

Gibbs, James S., Malide, Daniela, Hornung, Felicita, Bennink, Jack R., Yewdell, Jonathan W.

The 11th influenza A virus gene product is an 87-amino-acid protein provisionally named PB1-F2 (because it is encoded by an open reading frame overlapping the PB1 open reading frame). A significant...

The Export of Major Histocompatibility Complex Class I Molecules from the Endoplasmic Reticulum of Rat Brown Adipose Cells Is Acutely Stimulated by Insulin

Malide, Daniela, Yewdell, Jonathan W., Bennink, Jack R., Cushman, Samuel W.

Major histocompatibility complex class I (MHC-I) molecules have been implicated in several nonimmunological functions including the regulation and intracellular trafficking of the insulin-responsive...

The Influenza A Virus PB1-F2 Protein Targets the Inner Mitochondrial Membrane via a Predicted Basic Amphipathic Helix That Disrupts Mitochondrial Function

Gibbs, James S., Malide, Daniela, Hornung, Felicita, Bennink, Jack R., Yewdell, Jonathan W.

The 11th influenza A virus gene product is an 87-amino-acid protein provisionally named PB1-F2 (because it is encoded by an open reading frame overlapping the PB1 open reading frame). A significant...

CLA-1 and its splicing variant CLA-2 mediate bacterial adhesion and cytosolic bacterial invasion in mammalian cells

Vishnyakova, Tatyana G., Kurlander, Roger, Bocharov, Alexander V., Baranova, Irina N., Chen, Zhigang, Abu-Asab, Mones S., ...

CD36 and LIMPII analog 1, CLA-1, and its splicing variant, CLA-2 (SR-BI and SR-BII in rodents), are human high density lipoprotein receptors with an identical extracellular domain which binds a...

Human mesenchymal stem cells exert potent antitumorigenic effects in a model of Kaposi's sarcoma

Khakoo, Aarif Y., Pati, Shibani, Anderson, Stasia A., Reid, William, Elshal, Mohamed F., Rovira, Ilsa I., ...

Emerging evidence suggests that both human stem cells and mature stromal cells can play an important role in the development and growth of human malignancies. In contrast to these tumor-promoting...

Perforin gene mutations in patients with acquired aplastic anemia

Solomou, Elena E., Gibellini, Federica, Stewart, Brian, Malide, Daniela, Berg, Maria, Visconte, Valeria, ...

Perforin is a cytolytic protein expressed mainly in activated cytotoxic lymphocytes and natural killer cells. Inherited perforin mutations account for 20% to 40% of familial hemophagocytic...

Deficient CD4+ CD25+ FOXP3+ T regulatory cells in acquired aplastic anemia

Solomou, Elena E., Rezvani, Katayoun, Mielke, Stephan, Malide, Daniela, Keyvanfar, Keyvan, Visconte, Valeria, ...

Regulatory T cells are believed to control the development and progression of autoimmunity by suppressing autoreactive T cells. Decreased numbers of CD4+CD25+ FOXP3+ T cells (Tregs) are associated...

Abnormal lymphangiogenesis in idiopathic pulmonary fibrosis with insights into cellular and molecular mechanisms

El-Chemaly, Souheil, Malide, Daniela, Zudaire, Enrique, Ikeda, Yoshihiko, Weinberg, Benjamin A., Pacheco-Rodriguez, Gustavo, ...

Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, debilitating respiratory disease whose pathogenesis is poorly understood. In IPF, the lung parenchyma undergoes extensive remodeling. We...

The facilitative glucose transporter GLUT3: 20 years of distinction

Simpson, Ian A., Dwyer, Donard, Malide, Daniela, Moley, Kelle H., Travis, Alexander, Vannucci, Susan J.

Glucose metabolism is vital to most mammalian cells, and the passage of glucose across cell membranes is facilitated by a family of integral membrane transporter proteins, the GLUTs. There are...