Daniele Fallin

Genome-wide linkage analysis of 723 affected relative pairs with late-onset Alzheimer's disease (2007)

Hamshere, Marian L., Holmans, Peter A., Avramopoulos, Dimitrios, Bassett, Susan S., Blacker, Deborah, Bertram, Lars, ...

Previous attempts to identify genetic loci conferring risk for late-onset Alzheimer's disease (LOAD) through linkage analysis have observed some regions of linkage in common. However, due to the...

Genome-wide linkage analysis of 723 affected relative pairs with late-onset Alzheimer's disease (2007)

Hamshere, Marian Lindsay, Holmans, Peter Alan, Avramopoulos, Dimitrios, Bassett, Susan S., Blacker, Deborah, Bertram, Lars, ...

Previous attempts to identify genetic loci conferring risk for late-onset Alzheimer's disease (LOAD) through linkage analysis have observed some regions of linkage in common. However, due to the...

Genome-wide linkage analysis of 723 affected relative pairs with late-onset Alzheimer's disease (2007)

Hamshere, Marian Lindsay, Holmans, Peter Alan, Avramopoulos, Dimitrios, Bassett, Susan S., Blacker, Deborah, Bertram, Lars, ...

Previous attempts to identify genetic loci conferring risk for late-onset Alzheimer's disease (LOAD) through linkage analysis have observed some regions of linkage in common. However, due to the...

APOLIPOPROTEIN E AND COGNITION IN COMMUNITY-BASED SAMPLES OF AFRICAN AMERICANS AND CAUCASIANS (2006)

Borenstein, Amy R., Mortimer, James A., Wu, Yougui, Jureidini-Webb, Fern M., Fallin, Daniele, Small, Brent J., ...

To compare relative frequencies of apolipoprotein E (APOE) alleles in African-American and Caucasian populations and test associations with cognition, we studied two community-based samples: one of...

Genetic analysis of case/control data using estimated haplotype frequencies: application to APOE locus variation and Alzheimer's disease. (2001)

Fallin, Daniele, Cohen, Annick, Essioux, Laurent, Chumakov, Ilya, Blumenfeld, Marta, Cohen, Daniel, ...

There is growing debate over the utility of multiple locus association analyses in the identification of genomic regions harboring sequence variants that influence common complex traits such as...

Accuracy of haplotype frequency estimation for biallelic loci, via the expectation-maximization algorithm for unphased diploid genotype data. (2000)

Fallin, Daniele, Schork, Nicholas J.

Haplotype analyses have become increasingly common in genetic studies of human disease because of their ability to identify unique chromosomal segments likely to harbor disease-predisposing genes....

Linkage disequilibrium analysis of biallelic DNA markers, human quantitative trait loci, and threshold-defined case and control subjects. (2000)

Schork, Nicholas J., Nath, Swapan K., Fallin, Daniele, Chakravarti, Aravinda

Linkage disequilibrium (LD) mapping has been applied to many simple, monogenic, overtly Mendelian human traits, with great success. However, extensions and applications of LD mapping approaches to...

Genetic Analysis of Case/Control Data Using Estimated Haplotype Frequencies: Application to APOE Locus Variation and Alzheimer's Disease

Fallin, Daniele, Cohen, Annick, Essioux, Laurent, Chumakov, Ilya, Blumenfeld, Marta, Cohen, Daniel, ...

There is growing debate over the utility of multiple locus association analyses in the identification of genomic regions harboring sequence variants that influence common complex traits such as...

Accuracy of Haplotype Frequency Estimation for Biallelic Loci, via the Expectation-Maximization Algorithm for Unphased Diploid Genotype Data

Fallin, Daniele, Schork, Nicholas J.

Haplotype analyses have become increasingly common in genetic studies of human disease because of their ability to identify unique chromosomal segments likely to harbor disease-predisposing genes....

Linkage Disequilibrium Analysis of Biallelic DNA Markers, Human Quantitative Trait Loci, and Threshold-Defined Case and Control Subjects

Schork, Nicholas J., Nath, Swapan K., Fallin, Daniele, Chakravarti, Aravinda

Linkage disequilibrium (LD) mapping has been applied to many simple, monogenic, overtly Mendelian human traits, with great success. However, extensions and applications of LD mapping approaches to...

Genetic Analysis of Case/Control Data Using Estimated Haplotype Frequencies: Application to APOE Locus Variation and Alzheimer's Disease

Fallin, Daniele, Cohen, Annick, Essioux, Laurent, Chumakov, Ilya, Blumenfeld, Marta, Cohen, Daniel, ...

There is growing debate over the utility of multiple locus association analyses in the identification of genomic regions harboring sequence variants that influence common complex traits such as...

KLOTHO Allele Status and the Risk of Early-Onset Occult Coronary Artery Disease

Arking, Dan E., Becker, Diane M., Yanek, Lisa R., Fallin, Daniele, Judge, Daniel P., Moy, Taryn F., ...

We previously identified a functional variant of KLOTHO (termed “KL-VS”), which harbors two amino acid substitutions in complete linkage disequilibrium and is associated with reduced human...

Accuracy of Haplotype Frequency Estimation for Biallelic Loci, via the Expectation-Maximization Algorithm for Unphased Diploid Genotype Data

Fallin, Daniele, Schork, Nicholas J.

Haplotype analyses have become increasingly common in genetic studies of human disease because of their ability to identify unique chromosomal segments likely to harbor disease-predisposing genes....

Linkage Disequilibrium Analysis of Biallelic DNA Markers, Human Quantitative Trait Loci, and Threshold-Defined Case and Control Subjects

Schork, Nicholas J., Nath, Swapan K., Fallin, Daniele, Chakravarti, Aravinda

Linkage disequilibrium (LD) mapping has been applied to many simple, monogenic, overtly Mendelian human traits, with great success. However, extensions and applications of LD mapping approaches to...