Mice deficient for the chromosome 21 ortholog Itsn1 exhibit vesicle-trafficking abnormalities (2009)
Yu, Yong, Chu, Po-Yin, Bowser, David N., Keating, Damien J., Dubach, Daphne, Harper, Ian, ...
Mice deficient for the chromosome 21 ortholog Itsn1 exhibit vesicle-trafficking abnormalities (2008)
Yu, Yong, Chu, Po-Yin, Bowser, David N., Keating, Damien J., Dubach, Daphne, Harper, Ian, ...
Enlarged early endosomes in the neurons of young Down syndrome (DS) and pre-Alzheimer’s disease (AD) brains suggest that a disturbance in endocytosis is one of the earliest hallmarks of AD...
Keating, Damien J., Dubach, Daphne, Zanin, Mark P., Yu, Yong, Martin, Katherine, Zhao, Yu-Feng, ...
Genes located on chromosome 21, over-expressed in Down syndrome (DS) and Alzheimer's disease (AD) and which regulate vesicle trafficking, are strong candidates for involvement in AD neuropathology....