Application of phage display to high throughput antibody generation and characterization (2007)
Schofield, Darren J, Pope, Anthony R, Clementel, Veronica, Buckell, Jenny, Chapple, Susan DJ, Clarke, Kay F, ...
Abstract We have created a high quality phage display library containing over 10 10 human antibodies and describe its use in the generation of antibodies on an unprecedented scale. We have selected,...
A simple vector system to improve performance and utilisation of recombinant antibodies (2006)
Martin, Cecile D, Rojas, Gertrudis, Mitchell, Joanne N, Vincent, Karen J, Wu, Jiahua, McCafferty, John, ...
Abstract Background Isolation of recombinant antibody fragments from antibody libraries is well established using technologies such as phage display. Phage display vectors are ideal for efficient...
Men, Ruhe, Yamashiro, Tetsu, Goncalvez, Ana P., Wernly, Claire, Schofield, Darren J., Emerson, Suzanne U., ...
A safe and effective dengue vaccine is still not available. Passive immunization with monoclonal antibodies from humans or nonhuman primates represents an attractive alternative for the prevention of...
A simple vector system to improve performance and utilisation of recombinant antibodies
Martin, Cecile D, Rojas, Gertrudis, Mitchell, Joanne N, Vincent, Karen J, Wu, Jiahua, McCafferty, John, ...
Men, Ruhe, Yamashiro, Tetsu, Goncalvez, Ana P., Wernly, Claire, Schofield, Darren J., Emerson, Suzanne U., ...
A safe and effective dengue vaccine is still not available. Passive immunization with monoclonal antibodies from humans or nonhuman primates represents an attractive alternative for the prevention of...
Application of phage display to high throughput antibody generation and characterization
Schofield, Darren J, Pope, Anthony R, Clementel, Veronica, Buckell, Jenny, Chapple, Susan DJ, Clarke, Kay F, ...
A phage display library has been constructed containing over 1010 human antibodies, allowing the large-scale generation of antibodies. Over 38,000 recombinant antibodies against 292 antigens were...