Darwin K. Berg

Pre- and postsynaptic actions of L1-CAM in nicotinic pathways. (2006)

Triana-Baltzer, Gallen B, Liu, Zhaoping, Berg, Darwin K

Cell adhesion molecules (CAMs) have long been known to guide axon outgrowth and pathfinding. More recent evidence indicates they contribute to synapse formation as well. The L1 family of IgCAMs has...

β-Amyloid peptide blocks the response of α7-containing nicotinic receptors on hippocampal neurons

Liu, Qing-song, Kawai, Hideki, Berg, Darwin K.

Alzheimer's disease produces a devastating decline in mental function, with profound effects on learning and memory. Early consequences of the disease include the specific loss of cholinergic neurons...

Inhibition of neuronal acetylcholine sensitivity by α-toxins from Bungarus multicinctus venom

Ravdin, Peter M., Berg, Darwin K.

Bungarus multicinctus venom contains several α-toxins in addition to the widely used α-bungarotoxin (Bgt 2.2). We have found that two of the α-toxins (Bgt 3.1 and 3.3) inhibit neuronal...

Binding of α-Bungarotoxin to Acetylcholine Receptors In Mammalian Muscle

Berg, Darwin K., Kelly, Regis B., Sargent, Peter B., Williamson, Patrick, Hall, Zach W.

Experiments were performed to determine the specificity of [125I]α-bungarotoxin binding to skeletal muscle. In adult rat diaphragm, [125I]α-bungarotoxin was found to bind almost exclusively to...

β-Amyloid peptide blocks the response of α7-containing nicotinic receptors on hippocampal neurons

Liu, Qing-song, Kawai, Hideki, Berg, Darwin K.

Alzheimer's disease produces a devastating decline in mental function, with profound effects on learning and memory. Early consequences of the disease include the specific loss of cholinergic neurons...

Inhibition of neuronal acetylcholine sensitivity by α-toxins from Bungarus multicinctus venom

Ravdin, Peter M., Berg, Darwin K.

Bungarus multicinctus venom contains several α-toxins in addition to the widely used α-bungarotoxin (Bgt 2.2). We have found that two of the α-toxins (Bgt 3.1 and 3.3) inhibit neuronal...

Binding of α-Bungarotoxin to Acetylcholine Receptors In Mammalian Muscle

Berg, Darwin K., Kelly, Regis B., Sargent, Peter B., Williamson, Patrick, Hall, Zach W.

Experiments were performed to determine the specificity of [125I]α-bungarotoxin binding to skeletal muscle. In adult rat diaphragm, [125I]α-bungarotoxin was found to bind almost exclusively to...

Reversible inhibition of GABAA receptors by α7-containing nicotinic receptors on the vertebrate postsynaptic neurons

Zhang, Jingming, Berg, Darwin K

Nicotinic acetylcholine receptors (nAChRs) are expressed throughout the central nervous system and influence a variety of higher order functions including learning and memory. While the effects of...

Two distinct classes of functional α7-containing nicotinic receptor on rat superior cervical ganglion neurons

Cuevas, Javier, Roth, Adelheid L, Berg, Darwin K

Nicotinic acetylcholine receptors (nAChRs) that bind α-bungarotoxin (αBgt) were studied on isolated rat superior cervical ganglion (SCG) neurons using whole-cell patch clamp recording...