David A. Garber

Neither LAT nor Open Reading Frame P Mutations Increase Expression of Spliced or Intron-Containing ICP0 Transcripts in Mouse Ganglia Latently Infected with Herpes Simplex Virus

Chen, Shun-Hua, Lee, Lily Yeh, Garber, David A., Schaffer, Priscilla A., Knipe, David M., Coen, Donald M.

Latent infections by herpes simplex virus are characterized by repression of productive-cycle gene expression. Several hypotheses to explain this repression involve inhibition of expression of the...

Blockade of T cell costimulation reveals interrelated actions of CD4+ and CD8+ T cells in control of SIV replication

Garber, David A., Silvestri, Guido, Barry, Ashley P., Fedanov, Andrew, Kozyr, Natalia, McClure, Harold, ...

In vivo blockade of CD28 and CD40 T cell costimulation pathways during acute simian immunodeficiency virus (SIV) infection of rhesus macaques was performed to assess the relative contributions of...

Roles of Target Cells and Virus-Specific Cellular Immunity in Primary Simian Immunodeficiency Virus Infection

Regoes, Roland R., Antia, Rustom, Garber, David A., Silvestri, Guido, Feinberg, Mark B., Staprans, Silvija I.

There is an ongoing debate on whether acute human immunodeficiency virus infection is controlled by target cell limitation or by virus-specific cellular immunity. To resolve this question, we...

Divergent Host Responses during Primary Simian Immunodeficiency Virus SIVsm Infection of Natural Sooty Mangabey and Nonnatural Rhesus Macaque Hosts

Silvestri, Guido, Fedanov, Andrew, Germon, Stephanie, Kozyr, Natalia, Kaiser, William J., Garber, David A., ...

To understand how natural sooty mangabey hosts avoid AIDS despite high levels of simian immunodeficiency virus (SIV) SIVsm replication, we inoculated mangabeys and nonnatural rhesus macaque hosts...

Neither LAT nor Open Reading Frame P Mutations Increase Expression of Spliced or Intron-Containing ICP0 Transcripts in Mouse Ganglia Latently Infected with Herpes Simplex Virus

Chen, Shun-Hua, Lee, Lily Yeh, Garber, David A., Schaffer, Priscilla A., Knipe, David M., Coen, Donald M.

Latent infections by herpes simplex virus are characterized by repression of productive-cycle gene expression. Several hypotheses to explain this repression involve inhibition of expression of the...

Blockade of T cell costimulation reveals interrelated actions of CD4+ and CD8+ T cells in control of SIV replication

Garber, David A., Silvestri, Guido, Barry, Ashley P., Fedanov, Andrew, Kozyr, Natalia, McClure, Harold, ...

In vivo blockade of CD28 and CD40 T cell costimulation pathways during acute simian immunodeficiency virus (SIV) infection of rhesus macaques was performed to assess the relative contributions of...

Roles of Target Cells and Virus-Specific Cellular Immunity in Primary Simian Immunodeficiency Virus Infection

Regoes, Roland R., Antia, Rustom, Garber, David A., Silvestri, Guido, Feinberg, Mark B., Staprans, Silvija I.

There is an ongoing debate on whether acute human immunodeficiency virus infection is controlled by target cell limitation or by virus-specific cellular immunity. To resolve this question, we...

Divergent Host Responses during Primary Simian Immunodeficiency Virus SIVsm Infection of Natural Sooty Mangabey and Nonnatural Rhesus Macaque Hosts

Silvestri, Guido, Fedanov, Andrew, Germon, Stephanie, Kozyr, Natalia, Kaiser, William J., Garber, David A., ...

To understand how natural sooty mangabey hosts avoid AIDS despite high levels of simian immunodeficiency virus (SIV) SIVsm replication, we inoculated mangabeys and nonnatural rhesus macaque hosts...

Differences and Similarities in Viral Life Cycle Progression and Host Cell Physiology after Infection of Human Dendritic Cells with Modified Vaccinia Virus Ankara and Vaccinia Virus

Chahroudi, Ann, Garber, David A., Reeves, Patrick, Liu, Luzheng, Kalman, Daniel, Feinberg, Mark B.

Modified vaccinia virus Ankara (MVA) is an attenuated strain of vaccinia virus (VV) that has attracted significant attention as a candidate viral vector vaccine for immunization against infectious...

Estimating the Effectiveness of Simian Immunodeficiency Virus-Specific CD8+ T Cells from the Dynamics of Viral Immune Escape▿

Mandl, Judith N., Regoes, Roland R., Garber, David A., Feinberg, Mark B.

Antiviral CD8+ T cells are thought to play a significant role in limiting the viremia of human and simian immunodeficiency virus (HIV and SIV, respectively) infections. However, it has not been...