Mark Eppinger, M. J. Rosovitz, Wolfgang Florian Fricke, David A. Rasko, Galina Kokorina, Corinne Fayolle, ...
The first reported Far East scarlet-like fever (FESLF) epidemic swept the Pacific coastal region of Russia in the late 1950s. Symptoms of the severe infection included erythematous skin rash and...
Rasko, David A., Ravel, Jacques, Okstad, Ole A., Helgason, Erlendur, Cer, Regina Z., Jiang, Lingxia, ...
We sequenced the complete genome of Bacillus cereus ATCC 10987, a non-lethal dairy isolate in the same genetic subgroup as Bacillus anthracis. Comparison of the chromosomes demonstrated that B.cereus...
Hoffmaster, Alex R., Ravel, Jacques, Rasko, David A., Chapman, Gail D., Chute, Michael D., Marston, CHung K., ...
Bacillus anthracis is the etiologic agent of anthrax, an acute fatal disease among mammals. It was thought to differ from Bacillus cereus, an opportunistic pathogen and cause of food poisoning, by...
Myers, Garry S.A., Rasko, David A., Cheung, Jackie K., Ravel, Jacques, Seshadri, Rekha, DeBoy, Robert T., ...
Clostridium perfringens is a Gram-positive, anaerobic spore-forming bacterium commonly found in soil, sediments, and the human gastrointestinal tract. C. perfringens is responsible for a wide...
Myers, Garry S.A., Rasko, David A., Cheung, Jackie K., Ravel, Jacques, Seshadri, Rekha, DeBoy, Robert T., ...
Clostridium perfringens is a Gram-positive, anaerobic spore-forming bacterium commonly found in soil, sediments, and the human gastrointestinal tract. C. perfringens is responsible for a wide...
The first decade of microbial genomics: what have we learned and where are we going next? (2005)
Rasko, David A, Mongodin, Emmanuel F
A report on the International Conference on Microbial Genomics, Halifax, Canada, 13-16 April 2005.
Visualization of comparative genomic analyses by BLAST score ratio (2005)
Rasko, David A, Myers, Garry SA, Ravel, Jacques
Abstract Background The first microbial genome sequence, Haemophilus influenzae , was published in 1995. Since then, more than 400 microbial genome sequences have been completed or commenced. This...
Derrick E. Fouts, Emmanuel F. Mongodin, Robert E. Mandrell, William G. Miller, David A. Rasko, Jacques Ravel, ...
Although the single genome sequence of the human Campylobacter jejuni yielded some insight, comparison of multiple species of the same genus elucidated greater understanding of virulence mechanisms.
Derrick E. Fouts, Emmanuel F. Mongodin, Robert E. Mandrell, William G. Miller, David A. Rasko, Jacques Ravel, ...
Sequencing and comparative genome analysis of four strains of Campylobacter including C. lari RM2100, C. upsaliensis RM3195, and C. coli RM2228 has revealed major structural differences that are...
Nelson, Karen E., Fouts, Derrick E., Mongodin, Emmanuel F., Ravel, Jacques, DeBoy, Robert T., Kolonay, James F., ...
The genomes of three strains of Listeria monocytogenes that have been associated with food‐borne illness in the USA were subjected to whole genome comparative analysis. A total of 51, 97 and 69...
Rasko, David A., Ravel, Jacques, Økstad, Ole Andreas, Helgason, Erlendur, Cer, Regina Z., Jiang, Lingxia, ...
We sequenced the complete genome of Bacillus cereus ATCC 10987, a non‐lethal dairy isolate in the same genetic subgroup as Bacillus anthracis. Comparison of the chromosomes demonstrated that...
Repression of bacterial motility by a novel fimbrial gene product
Li, Xin, Rasko, David A., Lockatell, C.Virginia, Johnson, David E., Mobley, Harry L.T.
Proteus mirabilis is a common uropathogen in patients with long-term catheterization or with structural or functional abnormalities in the urinary tract. The mannose-resistant, Proteus-like (MR/P)...
Lozniewski, Alain, Haristoy, Xavier, Rasko, David A., Hatier, Renée, Plénat, François, Taylor, Diane E., ...
The role of Helicobacter pylori lipopolysaccharide (LPS) Lewis antigens in infection is still not well known. We investigated the influence of Lewis antigen expression by H. pylori on its...
Formation and Composition of the Bacillus anthracis Endospore†
Liu, Hongbin, Bergman, Nicholas H., Thomason, Brendan, Shallom, Shamira, Hazen, Alyson, Crossno, Joseph, ...
The endospores of Bacillus anthracis are the infectious particles of anthrax. Spores are dormant bacterial morphotypes able to withstand harsh environments for decades, which contributes to their...
Heimer, Susan R., Rasko, David A., Lockatell, C. Virginia, Johnson, David E., Mobley, Harry L. T.
We have identified two chromosomal open reading frames in uropathogenic Escherichia coli (UPEC) strain CFT073 which are highly homologous to serine protease autotransporters Pic and Tsh. Both cloned...
Rasko, David A., Ravel, Jacques, Økstad, Ole Andreas, Helgason, Erlendur, Cer, Regina Z., Jiang, Lingxia, ...
We sequenced the complete genome of Bacillus cereus ATCC 10987, a non-lethal dairy isolate in the same genetic subgroup as Bacillus anthracis. Comparison of the chromosomes demonstrated that B.cereus...
Nelson, Karen E., Fouts, Derrick E., Mongodin, Emmanuel F., Ravel, Jacques, DeBoy, Robert T., Kolonay, James F., ...
The genomes of three strains of Listeria monocytogenes that have been associated with food-borne illness in the USA were subjected to whole genome comparative analysis. A total of 51, 97 and 69...
Hoffmaster, Alex R., Ravel, Jacques, Rasko, David A., Chapman, Gail D., Chute, Michael D., Marston, Chung K., ...
Bacillus anthracis is the etiologic agent of anthrax, an acute fatal disease among mammals. It was thought to differ from Bacillus cereus, an opportunistic pathogen and cause of food poisoning, by...
Fouts, Derrick E, Mongodin, Emmanuel F, Mandrell, Robert E, Miller, William G, Rasko, David A, Ravel, Jacques, ...
Sequencing and comparative genome analysis of four strains of Campylobacter including C. lari RM2100, C. upsaliensis RM3195, and C. coli RM2228 has revealed major structural differences that are...
Schmidt, Eric W., Nelson, James T., Rasko, David A., Sudek, Sebastian, Eisen, Jonathan A., Haygood, Margo G., ...
Prochloron spp. are obligate cyanobacterial symbionts of many didemnid family ascidians. It has been proposed that the cyclic peptides of the patellamide class found in didemnid extracts are...
The first decade of microbial genomics: what have we learned and where are we going next?
Rasko, David A, Mongodin, Emmanuel F
A report on the International Conference on Microbial Genomics, Halifax, Canada, 13-16 April 2005.
Sequencing Bacillus anthracis Typing Phages Gamma and Cherry Reveals a Common Ancestry
Fouts, Derrick E., Rasko, David A., Cer, Regina Z., Jiang, Lingxia, Fedorova, Nadia B., Shvartsbeyn, Alla, ...
The genetic relatedness of the Bacillus anthracis typing phages Gamma and Cherry was determined by nucleotide sequencing and comparative analysis. The genomes of these two phages were identical...
Repression of bacterial motility by a novel fimbrial gene product
Li, Xin, Rasko, David A., Lockatell, C.Virginia, Johnson, David E., Mobley, Harry L.T.
Proteus mirabilis is a common uropathogen in patients with long-term catheterization or with structural or functional abnormalities in the urinary tract. The mannose-resistant, Proteus-like (MR/P)...
Lozniewski, Alain, Haristoy, Xavier, Rasko, David A., Hatier, Renée, Plénat, François, Taylor, Diane E., ...
The role of Helicobacter pylori lipopolysaccharide (LPS) Lewis antigens in infection is still not well known. We investigated the influence of Lewis antigen expression by H. pylori on its...
Formation and Composition of the Bacillus anthracis Endospore†
Liu, Hongbin, Bergman, Nicholas H., Thomason, Brendan, Shallom, Shamira, Hazen, Alyson, Crossno, Joseph, ...
The endospores of Bacillus anthracis are the infectious particles of anthrax. Spores are dormant bacterial morphotypes able to withstand harsh environments for decades, which contributes to their...
Heimer, Susan R., Rasko, David A., Lockatell, C. Virginia, Johnson, David E., Mobley, Harry L. T.
We have identified two chromosomal open reading frames in uropathogenic Escherichia coli (UPEC) strain CFT073 which are highly homologous to serine protease autotransporters Pic and Tsh. Both cloned...
Rasko, David A., Ravel, Jacques, Økstad, Ole Andreas, Helgason, Erlendur, Cer, Regina Z., Jiang, Lingxia, ...
We sequenced the complete genome of Bacillus cereus ATCC 10987, a non-lethal dairy isolate in the same genetic subgroup as Bacillus anthracis. Comparison of the chromosomes demonstrated that B.cereus...
Nelson, Karen E., Fouts, Derrick E., Mongodin, Emmanuel F., Ravel, Jacques, DeBoy, Robert T., Kolonay, James F., ...
The genomes of three strains of Listeria monocytogenes that have been associated with food-borne illness in the USA were subjected to whole genome comparative analysis. A total of 51, 97 and 69...
Hoffmaster, Alex R., Ravel, Jacques, Rasko, David A., Chapman, Gail D., Chute, Michael D., Marston, Chung K., ...
Bacillus anthracis is the etiologic agent of anthrax, an acute fatal disease among mammals. It was thought to differ from Bacillus cereus, an opportunistic pathogen and cause of food poisoning, by...
Fouts, Derrick E, Mongodin, Emmanuel F, Mandrell, Robert E, Miller, William G, Rasko, David A, Ravel, Jacques, ...
Sequencing and comparative genome analysis of four strains of Campylobacter including C. lari RM2100, C. upsaliensis RM3195, and C. coli RM2228 has revealed major structural differences that are...
Schmidt, Eric W., Nelson, James T., Rasko, David A., Sudek, Sebastian, Eisen, Jonathan A., Haygood, Margo G., ...
Prochloron spp. are obligate cyanobacterial symbionts of many didemnid family ascidians. It has been proposed that the cyclic peptides of the patellamide class found in didemnid extracts are...
The first decade of microbial genomics: what have we learned and where are we going next?
Rasko, David A, Mongodin, Emmanuel F
A report on the International Conference on Microbial Genomics, Halifax, Canada, 13-16 April 2005.
Sequencing Bacillus anthracis Typing Phages Gamma and Cherry Reveals a Common Ancestry
Fouts, Derrick E., Rasko, David A., Cer, Regina Z., Jiang, Lingxia, Fedorova, Nadia B., Shvartsbeyn, Alla, ...
The genetic relatedness of the Bacillus anthracis typing phages Gamma and Cherry was determined by nucleotide sequencing and comparative analysis. The genomes of these two phages were identical...
Skewed genomic variability in strains of the toxigenic bacterial pathogen, Clostridium perfringens
Myers, Garry S.A., Rasko, David A., Cheung, Jackie K., Ravel, Jacques, Seshadri, Rekha, DeBoy, Robert T., ...
Clostridium perfringens is a Gram-positive, anaerobic spore-forming bacterium commonly found in soil, sediments, and the human gastrointestinal tract. C. perfringens is responsible for a wide...
Multiple Antimicrobial Resistance in Plague: An Emerging Public Health Risk
Welch, Timothy J., Fricke, W. Florian, McDermott, Patrick F., White, David G., Rosso, Marie-Laure, Rasko, David A., ...
Antimicrobial resistance in Yersinia pestis is rare, yet constitutes a significant international public health and biodefense threat. In 1995, the first multidrug resistant (MDR) isolate of Y. pestis...
Rasko, David A., Rosovitz, M. J., Økstad, Ole Andreas, Fouts, Derrick E., Jiang, Lingxia, Cer, Regina Z., ...
The plasmids of the members of the Bacillus cereus sensu lato group of organisms are essential in defining the phenotypic traits associated with pathogenesis and ecology. For example, Bacillus...
Eppinger, Mark, Rosovitz, M. J, Fricke, Wolfgang Florian, Rasko, David A, Kokorina, Galina, Fayolle, Corinne, ...
The first reported Far East scarlet-like fever (FESLF) epidemic swept the Pacific coastal region of Russia in the late 1950s. Symptoms of the severe infection included erythematous skin rash and...
Defining Genomic Islands and Uropathogen-Specific Genes in Uropathogenic Escherichia coli▿
Lloyd, Amanda L., Rasko, David A., Mobley, Harry L. T.
Uropathogenic Escherichia coli (UPEC) strains are responsible for the majority of uncomplicated urinary tract infections, which can present clinically as cystitis or pyelonephritis. UPEC strain...
Russell, Regan M., Sharp, Faith C., Rasko, David A., Sperandio, Vanessa
Transcription of the locus of enterocyte effacement (LEE) genes in enterohemorrhagic Escherichia coli (EHEC) is regulated by the LEE-encoded Ler and GrlR/GrlA proteins as well as the non-LEE-encoded...
Wang, Wei, Reitzer, Larry, Rasko, David A., Pearson, Melanie M., Blick, Robert J., Laurence, Cassie, ...
The nucleotide sequence from the genome of Moraxella catarrhalis ATCC 43617 was annotated and used both to assess the metabolic capabilities and limitations of this bacterium and to design probes for...
Kendall, Melissa M., Rasko, David A., Sperandio, Vanessa
Intrakingdom cell-to-cell communication and interkingdom cell-to-cell communication play essential roles in the virulence of enterohemorrhagic Escherichia coli (EHEC). Four signals, autoinducer 2...
Huntley, Jason F., Conley, Patrick G., Rasko, David A., Hagman, Kayla E., Apicella, Michael A., Norgard, Michael V.
Francisella tularensis is a gram-negative intracellular bacterium and the causative agent of the zoonotic disease tularemia. F. tularensis is a category A select agent and thus a potential agent of...
Rasko, David A., Rosovitz, M. J., Myers, Garry S. A., Mongodin, Emmanuel F., Fricke, W. Florian, Gajer, Pawel, ...
Whole-genome sequencing has been skewed toward bacterial pathogens as a consequence of the prioritization of medical and veterinary diseases. However, it is becoming clear that in order to accurately...
CadA Negatively Regulates Escherichia coli O157:H7 Adherence and Intestinal Colonization▿ †
Vazquez-Juarez, Roberto C., Kuriakose, Jeeba A., Rasko, David A., Ritchie, Jennifer M., Kendall, Melissa M., Slater, Terry M., ...
Adherence of pathogenic Escherichia coli strains to intestinal epithelia is essential for infection. For enterohemorrhagic E. coli (EHEC) serotype O157:H7, we have previously demonstrated that...
The Complete Genome Sequence of Bacillus anthracis Ames “Ancestor”▿
Ravel, Jacques, Jiang, Lingxia, Stanley, Scott T., Wilson, Mark R., Decker, R. Scott, Read, Timothy D., ...
The pathogenic bacterium Bacillus anthracis has become the subject of intense study as a result of its use in a bioterrorism attack in the United States in September and October 2001. Previous...
Characterization of the Complete Zwittermicin A Biosynthesis Gene Cluster from Bacillus cereus▿ †
Kevany, Brian M., Rasko, David A., Thomas, Michael G.
Bacillus cereus UW85 produces the linear aminopolyol antibiotic zwittermicin A (ZmA). This antibiotic has diverse biological activities, such as suppression of disease in plants caused by protists,...
The QseC Adrenergic Signaling Cascade in Enterohemorrhagic E. coli (EHEC)
Hughes, David T., Clarke, Marcie B., Yamamoto, Kaneyoshi, Rasko, David A., Sperandio, Vanessa
The ability to respond to stress is at the core of an organism's survival. The hormones epinephrine and norepinephrine play a central role in stress responses in mammals, which require the...
Reading, Nicola C., Rasko, David A., Torres, Alfredo G., Sperandio, Vanessa
Bacterial pathogens sense host cues to activate expression of virulence genes. Most of these signals are sensed through histidine kinases (HKs), which comprise the main sensory mechanism in bacteria....
The Role of Genomics in the Identification, Prediction, and Prevention of Biological Threats
Fricke, W. Florian, Rasko, David A., Ravel, Jacques
In all likelihood, it is only a matter of time before our public health system will face a major biological threat, whether intentionally dispersed or originating from a known or newly emerging...