Somatic mutations affect key pathways in lung adenocarcinoma (2008)
Ding, Li, Getz, Gad, Wheeler, David A., Mardis, Elaine R., McLellan, Michael D., Cibulskis, Kristian, ...
Determining the genetic basis of cancer requires comprehensive analyses of large collections of histopathologically well- classified primary tumours. Here we report the results of a collaborative...
Somatic mutations affect key pathways in lung adenocarcinoma (2008)
Ding, Li, Getz, Gad, Wheeler, David A., Mardis, Elaine R., McLellan, Michael D., Cibulskis, Kristian, ...
Characterizing the cancer genome in lung adenocarcinoma (2007)
Weir, Barbara A., Woo, Michele S., Getz, Gad, Perner, Sven, Ding, Li, Beroukhim, Rameen, ...
Somatic alterations in cellular DNA underlie almost all human cancers(1). The prospect of targeted therapies(2) and the development of high-resolution, genome-wide approaches(3-8) are now spurring...
Razvan Peteanu, Vittal Aithal, Toby Barrick, Gunther Birznieks, Matt Curtin, Ilya Gulko, ...
Following the publication of version 2.0, the author has received useful comments and contributions from the following people (in alphabetical order): Jesús López de Aguileta
Razvan Peteanu, Vittal Aithal, Toby Barrick, Gunther Birznieks, Matt Curtin, Ilya Gulko, ...
Following the publication of version 2.0, the author has received useful comments and contributions from the following people (in alphabetical order): Jesús López de Aguileta
1.1 Lovelace's Purpose and Expected Users (2007)
Lovelace An, David A. Wheeler, N. Beauregard St
Lovelace is a free interactive tutorial for Ada 95 [RM 95] and is available through the World Wide Web (WWW). This paper describes Lovelace, including basic facts about it, its organization,...
A second generation human haplotype map of over 3.1 million SNPs (2007)
Frazer, Kelly A., Ballinger, Dennis G., Cox, David R., Hinds, David A., Stuve, Laura L., Gibbs, Richard A., ...
We describe the Phase II HapMap, which characterizes over 3.1 million human single nucleotide polymorphisms (SNPs) genotyped in 270 individuals from four geographically diverse populations and...
Margulies, Elliott H., Cooper, Gregory M., Asimenos, George, Thomas, Daryl J., Dewey, Colin N., Siepel, Adam, ...
A key component of the ongoing ENCODE project involves rigorous comparative sequence analyses for the initially targeted 1% of the human genome. Here, we present orthologous sequence generation,...
Characterizing the cancer genome in lung adenocarcinoma (2007)
Weir, Barbara A., Woo, Michele S., Getz, Gad, Perner, Sven, Ding, Li, Beroukhim, Rameen, ...
Fife, Dennis W., Wheeler, David A., Frame, Michael, Popelas, Judy
This annotated briefing describes the results of a survey of Ballistic Missile Defense (BMD) contractor software engineering environments (SEEs). It also reports the current status of selected...
The DNA sequence, annotation and analysis of human chromosome 3 (2006)
Muzny, Donna M., Scherer, Steven E., Kaul, Rajinder, Wang, Jing, Yu, Jun, ...
The DNA sequence, annotation and analysis of human chromosome 3 (2006)
Muzny, Donna M., Scherer, Steven E., Kaul, Rajinder, Wang, Jing, Yu, Jun, ...
The DNA sequence, annotation and analysis of human chromosome 3 (2006)
Muzny, Donna M., Scherer, Steven E., Kaul, Rajinder, Wang, Jing, Yu, Jun, ...
This presentation contains the views of the author and does not indicate (2006)
David A. Wheeler, Source Software (floss
programs have licenses giving users the freedom: – to run the program for any purpose, – to study and modify the program, and – to freely redistribute copies of either the original or modified...
SNPdetector: A Software Tool for Sensitive and Accurate SNP Detection (2005)
Jinghui Zhang, David A. Wheeler, Imtiaz Yakub, Sharon Wei, Raman Sood, William Rowe, ...
Identification of single nucleotide polymorphisms (SNPs) and mutations is important for the discovery of genetic predisposition to complex diseases. PCR resequencing is the method of choice for de...
Richards, Stephen, Liu, Yue, Bettencourt, Brian R., Hradecky, Pavel, Letovsky, Stan, Nielsen, Rasmus, ...
We have sequenced the genome of a second Drosophila species, Drosophila pseudoobscura, and compared this to the genome sequence of Drosophila melanogaster, a primary model organism. Throughout...
Richards, Stephen, Liu, Yue, Bettencourt, Brian R., Hradecky, Pavel, Letovsky, Stan, Nielsen, Rasmus, ...
The genome sequence of a second fruit fly, D. pseudoobscura, presents an opportunity for comparative analysis of a primary model organism D. melanogaster. The vast majority of Drosophila genes have...
Zhang, Zhengdong, Burch, Paula E., Cooney, Austin J., Lanz, Rainer B., Pereira, Fred A., Wu, Jiaqian, ...
Completion of the Rattus norvegicus genome sequence enabled a global inventory and analysis of the nuclear receptors (NRs) in three mammalian species. Forty-nine NR members were found in mouse, 48 in...
Open Source Software / Free Software (OSS/FS) has risen to prominence. If you're not sure what these terms mean, you can get an explanation of these terms and related information from my list of...
FOR A PARTICULAR PURPOSE. Secure Programming for Linux and Unix HOWTO (2003)
David A. Wheeler, Table Of Contents
This book provides a set of design and implementation guidelines for writing secure programs for Linux and Unix systems. Such programs include application programs used as viewers of remote data, web...
Celniker, Susan E, Wheeler, David A, Kronmiller, Brent, Carlson, Joseph W, Halpern, Aaron, Patel, Sandeep, ...
Abstract Background The Drosophila melanogaster genome was the first metazoan genome to have been sequenced by the whole-genome shotgun (WGS) method. Two issues relating to this achievement were...
The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective (2002)
Kaminker, Joshua S, Bergman, Casey M, Kronmiller, Brent, Carlson, Joseph, Svirskas, Robert, Patel, Sandeep, ...
Abstract Background Transposable elements are found in the genomes of nearly all eukaryotes. The recent completion of the Release 3 euchromatic genomic sequence of Drosophila melanogaster by the...
Secure Programming for Linux and Unix HOWTO (2000)
This paper provides a set of design and implementation guidelines for writing secure programs for Linux and Unix systems. Such programs include application programs used as viewers of remote data,...
Razvan Peteanu, Vittal Aithal, Toby Barrick, Gunther Birznieks, Matt Curtin, Ilya Gulko, ...
Following the publication of version 2.0, the author has received useful comments and contributions from the following people (in alphabetical order): Jesús López de Aguileta
Reviews of Selected System and Software Tools for Strategic Defense Applications. (1998)
Wheeler, David A., Fife, Dennis W., Sibley, Edgar H., Michael, J. B.
Information about certain software engineering tools relevant to the needs of the Strategic Defense Initiative (SDI) program is described in this paper. A broad sample of available off-the-shelf...
Software Testing Initiative for Strategic Defense Systems. (1998)
Brykczynski, Bill, Meeson, Reginald N., Youngblut, Christine, Wheeler, David A.
SDIO is planning to develop and deploy a ballistic missile defense system called Global Protection Against Limited Strikes (GPALS). Testing of GPALS software will play a critical role in ensuring the...
Analysis and Guidelines for Reusable Ada Software. (1998)
SDIO is developing the Global Protection Against Limited Strikes (GPALS) system. Much of the software is to be developed in Ada, and reuse will be considered in the software design and implementation...
Software Inspection Insertion Efforts for the Ballistic Missile Defense Organization. (1998)
Brykczynski, Bill, Meeson, Reginald N., Wheeler, David A.
Software inspection is an industry-proven process for improving quality and reducing cost and schedule risks during software development. Software inspections are highly effective at detecting and...
FY96 Analysis of the Ballistic Missile Defense Interoperability Standards. (1997)
Fife, Dennis W., Meeson, Reginald N., Wheeler, David A.
This briefing presents an assessment of the need for information technology interoperability standards and recommends actions that the Ballistic Missile Defense Organization (BMDO) can take based on...
Wheeler, David A., Fife, Dennis W.
This paper presents a generic process and lessons learned for developing hypertext versions of system development documents (e.g., requirements documents and design documents). System development...
Software inspection : an industry best practice (1996)
Wheeler, David A., Brykczynski, Bill, Meeson, Reginald N.
Incluye índice
Software inspection : an industry best practice / D.A. Wheeler, B. Brykczynski, R.N. Meeson. (1996)
Wheeler, David A., Brykczynski, Bill, Meeson, Reginald N.
Incluye índice
Software Inspection: Eliminating Software Defects (1994)
Bill Brykczynski, Reginald Meeson, David A. Wheeler
This paper identifies rework as a significant software development cost driver, describes how inspection reduces rework, explores the costs and benefits from inspection, and examines the current...
Celniker, Susan E, Wheeler, David A, Kronmiller, Brent, Carlson, Joseph W, Halpern, Aaron, Patel, Sandeep, ...
The Drosophila melanogaster genome was the first metazoan genome to be sequenced by whole-genome shotgun. Now, the sequence has been finished in a process designed to close gaps, improve sequence...
The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective
Kaminker, Joshua S, Bergman, Casey M, Kronmiller, Brent, Carlson, Joseph, Svirskas, Robert, Patel, Sandeep, ...
Using Release 3 of the euchromatic genomic sequence of Drosophila melanogaster, 85 known and eight novel families of transposable element have been identified, varying in copy number from one to 146....
Zhang, Zhengdong, Burch, Paula E., Cooney, Austin J., Lanz, Rainer B., Pereira, Fred A., Wu, Jiaqian, ...
Completion of the Rattus norvegicus genome sequence enabled a global inventory and analysis of the nuclear receptors (NRs) in three mammalian species. Forty-nine NR members were found in mouse, 48 in...
Gu, Peili, Goodwin, Bryan, Chung, Arthur C.-K., Xu, Xueping, Wheeler, David A., Price, Roger R., ...
Oct4 plays an essential role in maintaining the inner cell mass and pluripotence of embryonic stem (ES) cells. The expression of Oct4 is regulated by the proximal enhancer and promoter in the...
Gu, Peili, LeMenuet, Damien, Chung, Arthur C.-K., Mancini, Michael, Wheeler, David A., Cooney, Austin J.
Embryonic stem (ES) cell pluripotency and differentiation are controlled by a network of transcription factors and signaling molecules. Transcription factors such as Oct4 and Nanog are required for...
SNPdetector: A Software Tool for Sensitive and Accurate SNP Detection
Zhang, Jinghui, Wheeler, David A, Yakub, Imtiaz, Wei, Sharon, Sood, Raman, Rowe, William, ...
Identification of single nucleotide polymorphisms (SNPs) and mutations is important for the discovery of genetic predisposition to complex diseases. PCR resequencing is the method of choice for de...
Gu, Peili, Le Menuet, Damien, Chung, Arthur C.-K., Mancini, Michael A., Wheeler, David A., Cooney, Austin J.
Richards, Stephen, Liu, Yue, Bettencourt, Brian R., Hradecky, Pavel, Letovsky, Stan, Nielsen, Rasmus, ...
We have sequenced the genome of a second Drosophila species, Drosophila pseudoobscura, and compared this to the genome sequence of Drosophila melanogaster, a primary model organism. Throughout...
Celniker, Susan E, Wheeler, David A, Kronmiller, Brent, Carlson, Joseph W, Halpern, Aaron, Patel, Sandeep, ...
The Drosophila melanogaster genome was the first metazoan genome to be sequenced by whole-genome shotgun. Now, the sequence has been finished in a process designed to close gaps, improve sequence...
The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective
Kaminker, Joshua S, Bergman, Casey M, Kronmiller, Brent, Carlson, Joseph, Svirskas, Robert, Patel, Sandeep, ...
Using Release 3 of the euchromatic genomic sequence of Drosophila melanogaster, 85 known and eight novel families of transposable element have been identified, varying in copy number from one to 146....
Zhang, Zhengdong, Burch, Paula E., Cooney, Austin J., Lanz, Rainer B., Pereira, Fred A., Wu, Jiaqian, ...
Completion of the Rattus norvegicus genome sequence enabled a global inventory and analysis of the nuclear receptors (NRs) in three mammalian species. Forty-nine NR members were found in mouse, 48 in...
Richards, Stephen, Liu, Yue, Bettencourt, Brian R., Hradecky, Pavel, Letovsky, Stan, Nielsen, Rasmus, ...
We have sequenced the genome of a second Drosophila species, Drosophila pseudoobscura, and compared this to the genome sequence of Drosophila melanogaster, a primary model organism. Throughout...
Gu, Peili, Goodwin, Bryan, Chung, Arthur C.-K., Xu, Xueping, Wheeler, David A., Price, Roger R., ...
Oct4 plays an essential role in maintaining the inner cell mass and pluripotence of embryonic stem (ES) cells. The expression of Oct4 is regulated by the proximal enhancer and promoter in the...
Gu, Peili, LeMenuet, Damien, Chung, Arthur C.-K., Mancini, Michael, Wheeler, David A., Cooney, Austin J.
Embryonic stem (ES) cell pluripotency and differentiation are controlled by a network of transcription factors and signaling molecules. Transcription factors such as Oct4 and Nanog are required for...
SNPdetector: A Software Tool for Sensitive and Accurate SNP Detection
Zhang, Jinghui, Wheeler, David A, Yakub, Imtiaz, Wei, Sharon, Sood, Raman, Rowe, William, ...
Identification of single nucleotide polymorphisms (SNPs) and mutations is important for the discovery of genetic predisposition to complex diseases. PCR resequencing is the method of choice for de...
Gu, Peili, Le Menuet, Damien, Chung, Arthur C.-K., Mancini, Michael A., Wheeler, David A., Cooney, Austin J.
Analyses of deep mammalian sequence alignments and constraint predictions for 1% of the human genome
Margulies, Elliott H., Cooper, Gregory M., Asimenos, George, Thomas, Daryl J., Dewey, Colin N., Siepel, Adam, ...
A key component of the ongoing ENCODE project involves rigorous comparative sequence analyses for the initially targeted 1% of the human genome. Here, we present orthologous sequence generation,...
Novel MicroRNA Candidates and miRNA-mRNA Pairs in Embryonic Stem (ES) Cells
Gu, Peili, Reid, Jeffrey G., Gao, Xiaolian, Shaw, Chad A., Creighton, Chad, Tran, Peter L., ...
A Paradigm for Electronic Publication
Steffen, David L., Yarus, Sinai, Burch, Paula E., Wheeler, David A.
Web-Based Tools for Medical Education Information Management
Wheeler, David A., Steffen, David L., Deretchin, Louise F., Chapman, Jeanne Anne, Burch, Paula E., Beck, J. Robert, ...
Guo, Dong-Chuan, Papke, Christina L., Tran-Fadulu, Van, Regalado, Ellen S., Avidan, Nili, Johnson, Ralph Jay, ...
The vascular smooth muscle cell (SMC)-specific isoform of α-actin (ACTA2) is a major component of the contractile apparatus in SMCs located throughout the arterial system. Heterozygous ACTA2...