David Avarbock

Characterization of the cydAB-Encoded Cytochrome bd Oxidase from Mycobacterium smegmatis

Kana, Bavesh D., Weinstein, Edward A., Avarbock, David, Dawes, Stephanie S., Rubin, Harvey, Mizrahi, Valerie

The cydAB genes from Mycobacterium smegmatis have been cloned and characterized. The cydA and cydB genes encode the two subunits of a cytochrome bd oxidase belonging to the widely distributed family...

The Stringent Response of Mycobacterium tuberculosis Is Required for Long-Term Survival

Primm, Todd P., Andersen, Susan J., Mizrahi, Valerie, Avarbock, David, Rubin, Harvey, Barry, Clifton E.

The stringent response utilizes hyperphosphorylated guanine [(p)ppGpp] as a signaling molecule to control bacterial gene expression involved in long-term survival under starvation conditions. In...

The role of RelMtb-mediated adaptation to stationary phase in long-term persistence of Mycobacterium tuberculosis in mice

Dahl, John L., Kraus, Carl N., Boshoff, Helena I. M., Doan, Bernard, Foley, Korrie, Avarbock, David, ...

Long-term survival of nonreplicating Mycobacterium tuberculosis (Mtb) is ensured by the coordinated shutdown of active metabolism through a broad transcriptional program called the stringent...

Inhibitors of type II NADH:menaquinone oxidoreductase represent a class of antitubercular drugs

Weinstein, Edward A., Yano, Takahiro, Li, Lin-Sheng, Avarbock, David, Avarbock, Andrew, Helm, Douglas, ...

Mycobacterium tuberculosis (Mtb) is an obligate aerobe that is capable of long-term persistence under conditions of low oxygen tension. Analysis of the Mtb genome predicts the existence of a branched...

Characterization of the cydAB-Encoded Cytochrome bd Oxidase from Mycobacterium smegmatis

Kana, Bavesh D., Weinstein, Edward A., Avarbock, David, Dawes, Stephanie S., Rubin, Harvey, Mizrahi, Valerie

The cydAB genes from Mycobacterium smegmatis have been cloned and characterized. The cydA and cydB genes encode the two subunits of a cytochrome bd oxidase belonging to the widely distributed family...

The Stringent Response of Mycobacterium tuberculosis Is Required for Long-Term Survival

Primm, Todd P., Andersen, Susan J., Mizrahi, Valerie, Avarbock, David, Rubin, Harvey, Barry, Clifton E.

The stringent response utilizes hyperphosphorylated guanine [(p)ppGpp] as a signaling molecule to control bacterial gene expression involved in long-term survival under starvation conditions. In...

The role of RelMtb-mediated adaptation to stationary phase in long-term persistence of Mycobacterium tuberculosis in mice

Dahl, John L., Kraus, Carl N., Boshoff, Helena I. M., Doan, Bernard, Foley, Korrie, Avarbock, David, ...

Long-term survival of nonreplicating Mycobacterium tuberculosis (Mtb) is ensured by the coordinated shutdown of active metabolism through a broad transcriptional program called the stringent...

Inhibitors of type II NADH:menaquinone oxidoreductase represent a class of antitubercular drugs

Weinstein, Edward A., Yano, Takahiro, Li, Lin-Sheng, Avarbock, David, Avarbock, Andrew, Helm, Douglas, ...

Mycobacterium tuberculosis (Mtb) is an obligate aerobe that is capable of long-term persistence under conditions of low oxygen tension. Analysis of the Mtb genome predicts the existence of a branched...