David Broadhurst

Elliptic integral evaluations of Bessel moments (2008)

David H. Bailey, Jonathan M. Borwein, David Broadhurst, M. L. Glasser

We record what is known about the closed forms for various Bessel function moments arising in quantum field theory, condensed matter theory and other parts of mathematical physics. More generally, we...

Solutions by radicals at singular values k_N from new class invariants for N \equiv 3 mod 8 (2008)

Broadhurst, David

For square-free $N\equiv3$ mod 8 and $N$ coprime to 3, I show how to reduce the singular value $k_N$ to radicals, using a novel pair $[f,g]$ of real numbers that are algebraic integers of the Hilbert...

Elliptic integral evaluations of Bessel moments (2008)

Bailey, David H., Borwein, Jonathan M., Broadhurst, David, Glasser, M.L.

We record what is known about the closed forms for various Bessel function moments arising in quantum field theory, condensed matter theory and other parts of mathematical physics. More generally, we...

BIOINFORMATICS PYCHEM: A Multivariate Analysis Package for Python (2008)

Roger M. Jarvis, David Broadhurst, Helen Johnson, Noel M. O’boyle, Royston Goodacre, Martin Bishop

Summary: We have implemented a multivariate statistical analysis toolbox, with an optional standalone graphical user interface (GUI), using the Python scripting language. This is a free and open...

Elliptic integral evaluation of a Bessel moment by contour integration of a lattice Green function (2008)

Broadhurst, David

A proof is found for the elliptic integral evaluation of the Bessel moment $$M:=\int_0^\infty t I_0^2(t)K_0^2(t)K_0(2t) {\rm d}t ={1/12} {\bf K}(\sin(\pi/12)){\bf K}(\cos(\pi/12))...

Elliptic integral evaluations of Bessel moments (2008)

Bailey, David H., Borwein, Jonathan M., Broadhurst, David, Glasser, M. L.

We record what is known about the closed forms for various Bessel function moments arising in quantum field theory, condensed matter theory and other parts of mathematical physics. More generally, we...

Elliptic integral evaluations of Bessel moments (2008)

Bailey, David H., Borwein, Jonathan M., Broadhurst, David, Glasser, M.L.

We record what is known about the closed forms for various Bessel function moments arising in quantum field theory,condensed matter theory and other parts of mathematical physics. More generally, we...

Elliptic integral evaluations of Bessel moments and applications (2008)

David H. Bailey, Jonathan M. Borwein, David Broadhurst, M. L. Glasser

We record and substantially extend what is known about the closed forms for various Bessel function moments arising in quantum field theory, condensed matter theory and other parts of mathematical...

Elliptic integral evaluations of Bessel moments and applications (2008)

David H. Bailey, Jonathan M. Borwein, David Broadhurst, M. L. Glasser

We record and substantially extend what is known about the closed forms for various Bessel function moments arising in quantum field theory, condensed matter theory and other parts of mathematical...

Elliptic integral evaluations of Bessel moments and applications (2008)

David H Bailey, Jonathan M Borwein, David Broadhurst, M L Glasser

We record and substantially extend what is known about the closed forms for various Bessel function moments arising in quantum field theory, condensed matter theory and other parts of mathematical...

A GC-TOF-MS study of the stability of serum and urine metabolomes during the UK Biobank sample collection and preparation protocols (2008)

Dunn, Warwick B, Broadhurst, David, Ellis, David I, Brown, Marie, Halsall, Anthony, O’Hagan, Steven, ...

Background The stability of mammalian serum and urine in large metabolomic investigations is essential for accurate, valid and reproducible studies. The stability of mammalian serum and urine, either...

High Performance Computing Meets Experimental Mathematics (2007)

David H. Bailey, David Broadhurst, Yozo Hida, Xiaoye S. Li, Lawrence Berkeley, National Labratory, ...

In this paper we describe some novel applications of high performance computing in a discipline now known as “experimental mathematics. ” The paper reviews some recent published work, and then...

Soil differentiation using fingerprint Fourier transform infrared spectroscopy, chemometrics and genetic algorithm-based feature selection (2007)

Scullion, John, Elliot, Geoffrey N, Worgan, Hilary, Draper, John, Broadhurst, David

Soil is a complex environmental medium, particularly with respect to its biological and organic characteristics. Analytical approaches based on specific aspects of biological or organic variation may...

Using metabolic fingerprinting of plants for evaluating nitrogen deposition impacts on the landscape level (2006)

Gwynn-Jones, Dylan, Gidman, E, Goodacre, R, Broadhurst, David

Nitrogen emissions and atmospheric deposition are globally significant with the potential to alter ecosystem nutrient balance, provoking changes in vegetation composition. Shifts in plant...

Using metabolic fingerprinting of plants for evaluating nitrogen deposition impacts on the landscape level (2006)

Gidman, Eleanor A., Stevens, Carly J., Goodacre, Royston, Broadhurst, David, Emmett, Bridget, Gwynn-Jones, Dylan

Nitrogen emissions and atmospheric deposition are globally significant with the potential to alter ecosystem nutrient balance, provoking changes in vegetation composition. Shifts in plant...

PYCHEM: a multivariate analysis package for python (2006)

Jarvis, Roger M., Broadhurst, David, Johnson, Helen, O'Boyle, Noel M., Goodacre, Royston

Summary: We have implemented a multivariate statistical analysis toolbox, with an optional standalone graphical user interface (GUI), using the Python scripting language. This is a free and open...

Huntington disease patients and transgenic mice have similar pro-catabolic serum metabolite profiles (2006)

Underwood, Benjamin R., Broadhurst, David, Dunn, Warwick B., Ellis, David I., Michell, Andrew W., Vacher, Coralie, ...

There has been considerable progress recently towards developing therapeutic strategies for Huntington's disease (HD), with several compounds showing beneficial effects in transgenic mouse models....

Huntington disease patients and transgenic mice have similar pro-catabolic serum metabolite profiles (2006)

Underwood, Benjamin R., Broadhurst, David, Dunn, Warwick B., Ellis, David I., Michell, Andrew W., Vacher, Coralie, ...

There has been considerable progress recently towards developing therapeutic strategies for Huntington's disease (HD), with several compounds showing beneficial effects in transgenic mouse models....

Rapid identification of closely related muscle foods by vibrational spectroscopy and machine learning (2005)

Ellis, David I., Broadhurst, David, Clarke, S. J., Goodacre, Royston

Muscle foods are an integral part of the human diet and during the last few decades consumption of poultry products in particular has increased significantly. It is important for consumers, retailers...

Discrimination of the mode of action of antifungal substances using metabolic footprinting (2004)

Allen, Jess, Davey, Hazel M., Broadhurst, David, Rowland, Jem J., Oliver, Stephen G., Kell, Douglas B.

Diploid cells of Saccharomyces cerevisiae were grown under controlled conditions with a Bioscreen instrument, which permitted the essentially continuous registration of their growth via optical...

Rapid and quantitative detection of the microbial spoilage of beef by Fourier transform infrared spectroscopy and machine learning (2004)

Ellis, David I., Broadhurst, David, Goodacre, Royston

Beef is a commercially important and widely consumed muscle food and central to the protein intake of many societies. In the food industry no technology exists for the rapid and accurate detection of...

High-throughput metabolic fingerprinting of legume silage fermentations via Fourier transform infrared spectroscopy and chemometrics (2004)

Griffith, Gareth W, Johnson, Helen E, Broadhurst, David, Kell, Douglas B, Theodorou, Michael K, Merry, Roger J

Silage quality is typically assessed by the measurement of several individual parameters, including pH, lactic acid, acetic acid, bacterial numbers, and protein content. The objective of this study...

High-throughput metabolic fingerprinting of legume silage fermentations via Fourier transform infrared spectroscopy and chemometrics (2004)

Johnson, Helen E., Broadhurst, David, Kell, Douglas B., Theodorou, Michael K., Merry, Roger J., Griffith, Gareth W.

Silage quality is typically assessed by the measurement of several individual parameters, including pH, lactic acid, acetic acid, bacterial numbers, and protein content. The objective of this study...

Discrimination of the mode of action of antifungal substances using metabolic footprinting (2004)

Allen, Jess, Davey, Hazel M., Broadhurst, David, Rowland, Jem, Oliver, Stephen G., Kell, Douglas B.

Diploid cells of Saccharomyces cerevisiae were grown under controlled conditions with a Bioscreen instrument, which permitted the essentially continuous registration of their growth via optical...

High-throughput classification of yeast mutants for functional genomics using metabolic footprinting (2003)

Allen, Jess, Davey, Hazel M., Broadhurst, David, Heald, J. K., Rowland, Jem, Oliver, Stephen G., ...

Many technologies have been developed to help explain the function of genes discovered by systematic genome sequencing. At present, transcriptome and proteome studies dominate large-scale functional...

High-throughput classification of yeast mutants for functional genomics using metabolic footprinting (2003)

Allen, Jess, Davey, Hazel M., Broadhurst, David, Heald, Jim K, Rowland, Jem J, Oliver, Stephen G, ...

Many technologies have been developed to help explain the function of genes discovered by systematic genome sequencing. At present, transcriptome and proteome studies dominate large-scale functional...

Metabolic fingerprinting of salt-stressed tomatoes (2003)

Johnson, Helen E., Broadhurst, David, Goodacre, Royston, Smith, Aileen R.

The aim of this study was to adopt the approach of metabolic fingerprinting through the use of Fourier transform infrared (FT-IR) spectroscopy and chemometrics to study the effect of salinity on...

High-Throughput Metabolic Fingerprinting of Legume Silage Fermentations via Fourier Transform Infrared Spectroscopy (2003)

Helen E. Johnson, David Broadhurst, Douglas B. Kell, Michael K. Theodorou, Roger J. Merry, ...

Silage quality is typically assessed by the measurement of several individual parameters, including pH, lactic acid, acetic acid, bacterial numbers, and protein content. The objective of this study...

High Performance Computing Meets Experimental Mathematics (2003)

David H. Bailey, David Broadhurst, Yozo Hida, Xiaoye S. Li, Lawrence Berkeley, National Labratory, ...

In this paper we describe some novel applications of high performance computing in a discipline now known as “experimental mathematics. ” The paper reviews some recent published work, and then...

Rapid and quantitative detection of the microbial spoilage of meat using FT-IR spectroscopy and machine learning (2002)

Ellis, D. I., Broadhurst, David, Kell, Douglas B., Rowland, Jem, Goodacre, Royston

Fourier transform infrared (FT-IR) spectroscopy is a rapid, noninvasive technique with considerable potential for application in the food and related industries. We show here that this technique can...

Monitoring of Complex Industrial Bioprocesses for Metabolite Concentration Using Modern Spectroscopies and Machine Learning (2002)

McGovern, Aoife C., Broadhurst, David, Taylor, Janet, Gilbert, R. J., Winson, M. K., Kaderbhai, Naheed, ...

Two rapid vibrational spectroscopic approaches (diffuse reflectance-absorbance Fourier transform infrared [FT-IR] and dispersive Raman spectroscopy), and one mass spectrometric method based on in...

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, June 2002, p. 2822--2828 Vol. 68, No. 6 0099-2240/02/$04.000 DOI: 10.1128/AEM.68.6.2822--2828.2002 (2002)

Copyright American Society, David I. Ellis, David Broadhurst, Douglas B. Kell, Jem J. Rowl, Royston Goodacre

showing that at levels of 10 bacteriag the main biochemical indicator of spoilage was the onset of proteolysis. Thus, using FT-IR we were able to acquire a metabolic snapshot and quantify,...

A functional genomics strategy that uses metabolome data to reveal the phenotype of silent mutations (2001)

Raamsdonk, Léonie M., Teusink, Bas, Broadhurst, David, Zhang, Nianshu S., Hayes, Andrew, Walsh, Michael C., ...

A large proportion of the 6,000 genes present in the genome of Saccharomyces cerevisiae, and of those sequenced in other organisms, encode proteins of unknown function. Many of these genes are...

Experimental Mathematics: and Exact Computation (2000)

Jonathan M. Borwein, David Broadhurst

. Computation in Mathematics is fast becoming ubiquitous. My intention is to discuss \pure and applied experimental computation " from a mathematician's perspective. I shall try to...