David C. Grainger

The Escherichia coli RutR transcription factor binds at targets within genes as well as intergenic regions (2008)

Shimada, Tomohiro, Ishihama, Akira, Busby, Stephen J. W., Grainger, David C.

The Escherichia coli RutR protein is the master regulator of genes involved in pyrimidine catabolism. Here we have used chromatin immunoprecipitation in combination with DNA microarrays to measure...

Autoregulation of the Escherichia coli melR promoter: repression involves four molecules of MelR (2008)

Samarasinghe, Shivanthi, El-Robh, Mohamed Samir, Grainger, David C., Zhang, Wenke, Soultanas, Panos, Busby, Stephen J. W.

The Escherichia coli MelR protein is a transcription activator that autoregulates its own promoter by repressing transcription initiation. Optimal repression requires MelR binding to a site that...

Transcription factor distribution in Escherichia coli: studies with FNR protein (2007)

Grainger, David C., Aiba, Hirofumi, Hurd, Douglas, Browning, Douglas F., Busby, Stephen J. W.

Using chromatin immunoprecipitation (ChIP) and high-density microarrays, we have measured the distribution of the global transcription regulator protein, FNR, across the entire Escherichia coli...

Association of nucleoid proteins with coding and non-coding segments of the Escherichia coli genome (2006)

Grainger, David C., Hurd, Douglas, Goldberg, Martin D., Busby, Stephen J. W.

The Escherichia coli chromosome is condensed into an ill-defined structure known as the nucleoid. Nucleoid-associated DNA-binding proteins are involved in maintaining this structure and in mediating...

Association of nucleoid proteins with coding and non-coding segments of the Escherichia coli genome (2006)

Grainger, David C., Hurd, Douglas, Goldberg, Martin D., Busby, Stephen J. W.

The Escherichia coli chromosome is condensed into an ill-defined structure known as the nucleoid. Nucleoid-associated DNA-binding proteins are involved in maintaining this structure and in mediating...

Transcription factor distribution in Escherichia coli: studies with FNR protein (2006)

Grainger, David C., Aiba, Hirofumi, Hurd, Douglas, Browning, Douglas F., Busby, Stephen J. W.

Using chromatin immunoprecipitation (ChIP) and high-density microarrays, we have measured the distribution of the global transcription regulator protein, FNR, across the entire Escherichia coli...

Association of nucleoid proteins with coding and non-coding segments of the Escherichia coli genome (2006)

Grainger, David C., Hurd, Douglas, Goldberg, Martin D., Busby, Stephen J. W.

The Escherichia coli chromosome is condensed into an ill-defined structure known as the nucleoid. Nucleoid-associated DNA-binding proteins are involved in maintaining this structure and in mediating...

Transcription factor distribution in Escherichia coli: studies with FNR protein (2006)

Grainger, David C., Aiba, Hirofumi, Hurd, Douglas, Browning, Douglas F., Busby, Stephen J. W.

Using chromatin immunoprecipitation (ChIP) and high-density microarrays, we have measured the distribution of the global transcription regulator protein, FNR, across the entire Escherichia coli...

Copyright © 2004, American Society for Microbiology. All Rights Reserved. Genomic Studies with Escherichia coli MelR Protein: Applications of (2004)

Chromatin Immunoprecipitation, David C. Grainger, Timothy W. Overton, Joseph T. Wade, Eiji Tamai, Jon L. Hobman, ...

Escherichia coli MelR protein is a transcription activator that is essential for melibiose-dependent expression of the melAB genes. We have used chromatin immunoprecipitation to study the binding of...

Genomic Studies with Escherichia coli MelR Protein: Applications of Chromatin Immunoprecipitation and Microarrays

Grainger, David C., Overton, Timothy W., Reppas, Nikos, Wade, Joseph T., Tamai, Eiji, Hobman, Jon L., ...

Escherichia coli MelR protein is a transcription activator that is essential for melibiose-dependent expression of the melAB genes. We have used chromatin immunoprecipitation to study the binding of...

Studies of the distribution of Escherichia coli cAMP-receptor protein and RNA polymerase along the E. coli chromosome

Grainger, David C., Hurd, Douglas, Harrison, Marcus, Holdstock, Jolyon, Busby, Stephen J. W.

Chromatin immunoprecipitation and high-density microarrays have been used to monitor the distribution of the global transcription regulator Escherichia coli cAMP-receptor protein (CRP) and RNA...

Association of nucleoid proteins with coding and non-coding segments of the Escherichia coli genome

Grainger, David C., Hurd, Douglas, Goldberg, Martin D., Busby, Stephen J. W.

The Escherichia coli chromosome is condensed into an ill-defined structure known as the nucleoid. Nucleoid-associated DNA-binding proteins are involved in maintaining this structure and in mediating...

Genomic Studies with Escherichia coli MelR Protein: Applications of Chromatin Immunoprecipitation and Microarrays

Grainger, David C., Overton, Timothy W., Reppas, Nikos, Wade, Joseph T., Tamai, Eiji, Hobman, Jon L., ...

Escherichia coli MelR protein is a transcription activator that is essential for melibiose-dependent expression of the melAB genes. We have used chromatin immunoprecipitation to study the binding of...

Studies of the distribution of Escherichia coli cAMP-receptor protein and RNA polymerase along the E. coli chromosome

Grainger, David C., Hurd, Douglas, Harrison, Marcus, Holdstock, Jolyon, Busby, Stephen J. W.

Chromatin immunoprecipitation and high-density microarrays have been used to monitor the distribution of the global transcription regulator Escherichia coli cAMP-receptor protein (CRP) and RNA...

Association of nucleoid proteins with coding and non-coding segments of the Escherichia coli genome

Grainger, David C., Hurd, Douglas, Goldberg, Martin D., Busby, Stephen J. W.

The Escherichia coli chromosome is condensed into an ill-defined structure known as the nucleoid. Nucleoid-associated DNA-binding proteins are involved in maintaining this structure and in mediating...

Transcription factor distribution in Escherichia coli: studies with FNR protein

Grainger, David C., Aiba, Hirofumi, Hurd, Douglas, Browning, Douglas F., Busby, Stephen J. W.

Using chromatin immunoprecipitation (ChIP) and high-density microarrays, we have measured the distribution of the global transcription regulator protein, FNR, across the entire Escherichia coli...

Autoregulation of the Escherichia coli melR promoter: repression involves four molecules of MelR

Samarasinghe, Shivanthi, El-Robh, Mohamed Samir, Grainger, David C., Zhang, Wenke, Soultanas, Panos, Busby, Stephen J. W.

The Escherichia coli MelR protein is a transcription activator that autoregulates its own promoter by repressing transcription initiation. Optimal repression requires MelR binding to a site that...

The Escherichia coli RutR transcription factor binds at targets within genes as well as intergenic regions

Shimada, Tomohiro, Ishihama, Akira, Busby, Stephen J. W., Grainger, David C.

The Escherichia coli RutR protein is the master regulator of genes involved in pyrimidine catabolism. Here we have used chromatin immunoprecipitation in combination with DNA microarrays to measure...