David C. King

Cavitation occurrence around ultrasonic dental scalers (2009)

Felver, Bernhard, King, David C, Lea, Simon C., Price, Gareth J, Damien Walmsley, A.

Ultrasonic scalers are used in dentistry to remove calculus and other contaminants from teeth. One mechanism which may assist in the cleaning is cavitation generated in cooling water around the...

Transcriptional enhancement by GATA1-occupied DNA segments is strongly associated with evolutionary constraint on the binding site motif (2008)

Cheng, Yong, King, David C., Dore, Louis C., Zhang, Xinmin, Zhou, Yuepin, Zhang, Ying, ...

Tissue development and function are exquisitely dependent on proper regulation of gene expression, but it remains controversial whether the genomic signals controlling this process are subject to...

Finding cis-regulatory elements using comparative genomics: Some lessons from ENCODE data (2007)

King, David C., Taylor, James, Zhang, Ying, Cheng, Yong, Lawson, Heather A., Martin, Joel, ...

Identification of functional genomic regions using interspecies comparison will be most effective when the full span of relationships between genomic function and evolutionary constraint are...

28-Way vertebrate alignment and conservation track in the UCSC Genome Browser (2007)

Miller, Webb, Rosenbloom, Kate, Hardison, Ross C., Hou, Minmei, Taylor, James, Raney, Brian, ...

This article describes a set of alignments of 28 vertebrate genome sequences that is provided by the UCSC Genome Browser. The alignments can be viewed on the Human Genome Browser (March 2006...

ESPERR: Learning strong and weak signals in genomic sequence alignments to identify functional elements (2006)

Taylor, James, Tyekucheva, Svitlana, King, David C., Hardison, Ross C., Miller, Webb, Chiaromonte, Francesca

Genomic sequence signals—such as base composition, presence of particular motifs, or evolutionary constraint—have been used effectively to identify functional elements. However, approaches based...

Experimental validation of predicted mammalian erythroid cis-regulatory modules (2006)

Wang, Hao, Zhang, Ying, Cheng, Yong, Zhou, Yuepin, King, David C., Taylor, James, ...

Multiple alignments of genome sequences are helpful guides to functional analysis, but predicting cis-regulatory modules (CRMs) accurately from such alignments remains an elusive goal. We predict...

Experimental validation of predicted mammalian erythroid cis-regulatory modules (2006)

Wang, Hao, Zhang, Ying, Cheng, Yong, Zhou, Yuepin, King, David C., Taylor, James, ...

Multiple alignments of genome sequences are helpful guides to functional analysis, but predicting cis-regulatory modules (CRMs) accurately from such alignments remains an elusive goal. We predict...

ESPERR: Learning strong and weak signals in genomic sequence alignments to identify functional elements (2006)

Taylor, James, Tyekucheva, Svitlana, King, David C., Hardison, Ross C., Miller, Webb, Chiaromonte, Francesca

Genomic sequence signals—such as base composition, presence of particular motifs, or evolutionary constraint—have been used effectively to identify functional elements. However, approaches based...

Evaluation of regulatory potential and conservation scores for detecting cis-regulatory modules in aligned mammalian genome sequences (2005)

King, David C., Taylor, James, Elnitski, Laura, Chiaromonte, Francesca, Miller, Webb, Hardison, Ross C.

Techniques of comparative genomics are being used to identify candidate functional DNA sequences, and objective evaluations are needed to assess their effectiveness. Different analytical methods...

Evaluation of regulatory potential and conservation scores for detecting cis-regulatory modules in aligned mammalian genome sequences (2005)

King, David C., Taylor, James, Elnitski, Laura, Chiaromonte, Francesca, Miller, Webb, Hardison, Ross C.

Techniques of comparative genomics are being used to identify candidate functional DNA sequences, and objective evaluations are needed to assess their effectiveness. Different analytical methods...

From biomedicine to natural history research: EST resources for ambystomatid salamanders (2004)

Putta, Srikrishna, Smith, Jeramiah J, Walker, John A, Rondet, Mathieu, Weisrock, David W, Monaghan, James, ...

Abstract Background Establishing genomic resources for closely related species will provide comparative insights that are crucial for understanding diversity and variability at multiple levels of...

The Management Performance of the U.S. States (2002)

David C. King, Richard J. Zeckhauser, Mark T. Kim, Suzanne Cooper, Daniel Franklin, Tom Gais, ...

The Maxwell School's Government Performance Project recently rated the management successes of the 50 states in several areas, such as capital management, human resources and information...

Evaluation of regulatory potential and conservation scores for detecting cis-regulatory modules in aligned mammalian genome sequences

King, David C., Taylor, James, Elnitski, Laura, Chiaromonte, Francesca, Miller, Webb, Hardison, Ross C.

Techniques of comparative genomics are being used to identify candidate functional DNA sequences, and objective evaluations are needed to assess their effectiveness. Different analytical methods...

Evaluation of regulatory potential and conservation scores for detecting cis-regulatory modules in aligned mammalian genome sequences

King, David C., Taylor, James, Elnitski, Laura, Chiaromonte, Francesca, Miller, Webb, Hardison, Ross C.

Techniques of comparative genomics are being used to identify candidate functional DNA sequences, and objective evaluations are needed to assess their effectiveness. Different analytical methods...

Experimental validation of predicted mammalian erythroid cis-regulatory modules

Wang, Hao, Zhang, Ying, Cheng, Yong, Zhou, Yuepin, King, David C., Taylor, James, ...

Multiple alignments of genome sequences are helpful guides to functional analysis, but predicting cis-regulatory modules (CRMs) accurately from such alignments remains an elusive goal. We predict...

ESPERR: Learning strong and weak signals in genomic sequence alignments to identify functional elements

Taylor, James, Tyekucheva, Svitlana, King, David C., Hardison, Ross C., Miller, Webb, Chiaromonte, Francesca

Genomic sequence signals—such as base composition, presence of particular motifs, or evolutionary constraint—have been used effectively to identify functional elements. However, approaches based...

Finding cis-regulatory elements using comparative genomics: Some lessons from ENCODE data

King, David C., Taylor, James, Zhang, Ying, Cheng, Yong, Lawson, Heather A., Martin, Joel, ...

Identification of functional genomic regions using interspecies comparison will be most effective when the full span of relationships between genomic function and evolutionary constraint are...

28-Way vertebrate alignment and conservation track in the UCSC Genome Browser

Miller, Webb, Rosenbloom, Kate, Hardison, Ross C., Hou, Minmei, Taylor, James, Raney, Brian, ...

This article describes a set of alignments of 28 vertebrate genome sequences that is provided by the UCSC Genome Browser. The alignments can be viewed on the Human Genome Browser (March 2006...

Congressional Vote Options

David C. King, Richard J. Zeckhauser

Among political practitioners, there is conventional wisdom about the outcomes of critical and salient legislative votes. 'This vote,' we hear, ' will either win by a little or lose by a lot.'...

Transcriptional enhancement by GATA1-occupied DNA segments is strongly associated with evolutionary constraint on the binding site motif

Cheng, Yong, King, David C., Dore, Louis C., Zhang, Xinmin, Zhou, Yuepin, Zhang, Ying, ...

Tissue development and function are exquisitely dependent on proper regulation of gene expression, but it remains controversial whether the genomic signals controlling this process are subject to...