Janghoo Lim, Tong Hao, Chad Shaw, Akash J. Patel, Gábor Szabó, Jean-françois Rual, ...
Many human inherited neurodegenerative disorders are characterized by loss of balance due to cerebellar Purkinje cell (PC) degeneration. Although the disease-causing mutations have been identified...
An empirical framework for binary interactome mapping (2009)
Venkatesan, Kavitha, Rual, Jean-Francois, Vazquez, Alexei, Stelzl, Ulrich, Lemmens, Irma, Hirozane-Kishikawa, Tomoko, ...
Several attempts have been made to systematically map protein-protein interaction, or 'interactome', networks. However, it remains difficult to assess the quality and coverage of existing data sets....
An experimentally derived confidence score for binary protein-protein interactions (2009)
Braun, Pascal, Tasan, Murat, Dreze, Matija, Barrios-Rodiles, Miriam, Lemmens, Irma, Yu, Haiyuan, ...
Information on protein-protein interactions is of central importance for many areas of biomedical research. At present no method exists to systematically and experimentally assess the quality of...
Simonis, Nicolas, Rual, Jean-Francois, Carvunis, Anne-Ruxandra, Tasan, Murat, Lemmens, Irma, Hirozane-Kishikawa, Tomoko, ...
Abstract: To provide accurate biological hypotheses and elucidate global properties of cellular networks, systematic identification of protein-protein interactions must meet high quality standards....
Shifted Transversal Design smart-pooling for high coverage interactome mapping (2009)
Xin, Xiaofeng, Rual, Jean-François, Hirozane-Kishikawa, Tomoko, Hill, David E., Vidal, Marc, Boone, Charles, ...
“Smart-pooling,” in which test reagents are multiplexed in a highly redundant manner, is a promising strategy for achieving high efficiency, sensitivity, and specificity in systems-level...
A protein domain-based interactome network for C. elegans early embryogenesis (2008)
Boxem, Mike, Maliga, Zoltan, Klitgord, Niels, Li, Na, Lemmens, Irma, Mana, Miyeko, ...
Many protein-protein interactions are mediated through independently folding modular domains. Proteome-wide efforts to model protein-protein interaction or "interactome" networks have largely ignored...
Revisiting the Saccharomyces cerevisiae predicted ORFeome (2008)
Li, Qian-Ru, Carvunis, Anne-Ruxandra, Yu, Haiyuan, Han, Jing-Dong J., Zhong, Quan, Simonis, Nicolas, ...
Accurately defining the coding potential of an organism, i.e., all protein-encoding open reading frames (ORFs) or “ORFeome,” is a prerequisite to fully understand its biology. ORFeome annotation...
From genome to proteome: developing expression clone resources for the human genome (2006)
Temple, Gary, Lamesch, Philippe, Milstein, Stuart, Hill, David E., Wagner, Lukas, Moore, Troy, ...
From genome to proteome: developing expression clone resources for the human genome (2006)
Temple, Gary, Lamesch, Philippe, Milstein, Stuart, Hill, David E., Wagner, Lukas, Moore, Troy, ...
cDNA clones have long been valuable reagents for studying the structure and function of proteins. With recent access to the entire human genome sequence, it has become possible and highly productive...
Fernandez, Anita G., Gunsalus, Kristin C., Huang, Jerry, Chuang, Ling-Shiang, Ying, Nancy, Liang, Hsiao-lan, ...
Several RNA interference (RNAi)-based functional genomic projects have been performed in Caenorhabditis elegans to identify genes required during embryogenesis. These studies have demonstrated that...
Academia-Industry Collaboration: An Integral Element for Building "Omic" Resources (2004)
Hill, David E., Brasch, Michael A., Del Campo, Anthony A., Doucette-Stamm, Lynn, Garrels, James I., Glaven, Judith, ...
Lamesch, Philippe, Milstein, Stuart, Hao, Tong, Rosenberg, Jennifer, Li, Ning, Sequerra, Reynaldo, ...
The first version of the Caenorhabditis elegans ORFeome cloning project, based on release WS9 of Wormbase (August 1999), provided experimental verifications for ∼55% of predicted protein-encoding...
High-Throughput Expression of C. elegans Proteins (2004)
Luan, Chi-Hao, Qiu, Shihong, Finley, James B., Carson, Mike, Gray, Rita J., Huang, Wenying, ...
Proteome-scale studies of protein three-dimensional structures should provide valuable information for both investigating basic biology and developing therapeutics. Critical for these endeavors is...
Human ORFeome Version 1.1: A Platform for Reverse Proteomics (2004)
Rual, Jean-François, Hirozane-Kishikawa, Tomoko, Hao, Tong, Bertin, Nicolas, Li, Siming, Dricot, Amélie, ...
The advent of systems biology necessitates the cloning of nearly entire sets of protein-encoding open reading frames (ORFs), or ORFeomes, to allow functional studies of the corresponding proteomes....
Toward Improving Caenorhabditis elegans Phenome Mapping With an ORFeome-Based RNAi Library (2004)
Rual, Jean-François, Ceron, Julian, Koreth, John, Hao, Tong, Nicot, Anne-Sophie, Hirozane-Kishikawa, Tomoko, ...
The recently completed Caenorhabditis elegans genome sequence allows application of high-throughput (HT) approaches for phenotypic analyses using RNA interference (RNAi). As large phenotypic data...
A First Version of the Caenorhabditis elegans Promoterome (2004)
Dupuy, Denis, Li, Qian-Ru, Deplancke, Bart, Boxem, Mike, Hao, Tong, Lamesch, Philippe, ...
An important aspect of the development of systems biology approaches in metazoans is the characterization of expression patterns of nearly all genes predicted from genome sequences. Such...
Generation of the Brucella melitensis ORFeome Version 1.1 (2004)
Dricot, Amélie, Rual, Jean-François, Lamesch, Philippe, Bertin, Nicolas, Dupuy, Denis, Hao, Tong, ...
The bacteria of the Brucella genus are responsible for a worldwide zoonosis called brucellosis. They belong to the α-proteobacteria group, as many other bacteria that live in close association with...
The GCD1 gene product of Saccharomyces cercvisiae has been implicated in the coordination of the cell cycle with the general control of amirio acid biosynthesis (M. Wolfhcr et al., J. Mol. Biol. 96:...
We describe a simple method to quantitate the intracellular levels of charged tRNA species representing all 20 amino acids. Small RNA species are isolated from yeast cells under conditions where...
Use of Natural resource data in land and water planning / by David E. Hill and Hugo F. Thomas (1972)
Typescript.
Firefly “femmes fatales” acquire defensive steroids (lucibufagins) from their firefly prey
Eisner, Thomas, Goetz, Michael A., Hill, David E., Smedley, Scott R., Meinwald, Jerrold
Female fireflies of the genus Photuris, the so-called firefly “femmes fatales,” prey on male fireflies of the genus Photinus. The females are able to entrap the males by faking the flash signal...
AIS is an oncogene amplified in squamous cell carcinoma
Hibi, Kenji, Trink, Barry, Patturajan, Meera, Westra, William H., Caballero, Otávia L., Hill, David E., ...
We and others recently isolated a human p53 homologue (p40/p51/p63/p73L) and localized the gene to the distal long arm of chromosome 3. Here we sought to examine the role of p40/p73L, two variants...
Berrueta, Lisbeth, Kraeft, Stine-Katherine, Tirnauer, Jennifer S., Schuyler, Scott C., Chen, Lan Bo, Hill, David E., ...
The evolutionarily conserved protein EB1 originally was identified by its physical association with the carboxyl-terminal portion of the adenomatous polyposis coli (APC) tumor suppressor protein, an...
Lamesch, Philippe, Milstein, Stuart, Hao, Tong, Rosenberg, Jennifer, Li, Ning, Sequerra, Reynaldo, ...
The first version of the Caenorhabditis elegans ORFeome cloning project, based on release WS9 of Wormbase (August 1999), provided experimental verifications for ∼55% of predicted protein-encoding...
High-Throughput Expression of C. elegans Proteins
Luan, Chi-Hao, Qiu, Shihong, Finley, James B., Carson, Mike, Gray, Rita J., Huang, Wenying, ...
Proteome-scale studies of protein three-dimensional structures should provide valuable information for both investigating basic biology and developing therapeutics. Critical for these endeavors is...
Human ORFeome Version 1.1: A Platform for Reverse Proteomics
Rual, Jean-François, Hirozane-Kishikawa, Tomoko, Hao, Tong, Bertin, Nicolas, Li, Siming, Dricot, Amélie, ...
The advent of systems biology necessitates the cloning of nearly entire sets of protein-encoding open reading frames (ORFs), or ORFeomes, to allow functional studies of the corresponding proteomes....
Toward Improving Caenorhabditis elegans Phenome Mapping With an ORFeome-Based RNAi Library
Rual, Jean-François, Ceron, Julian, Koreth, John, Hao, Tong, Nicot, Anne-Sophie, Hirozane-Kishikawa, Tomoko, ...
The recently completed Caenorhabditis elegans genome sequence allows application of high-throughput (HT) approaches for phenotypic analyses using RNA interference (RNAi). As large phenotypic data...
A First Version of the Caenorhabditis elegans Promoterome
Dupuy, Denis, Li, Qian-Ru, Deplancke, Bart, Boxem, Mike, Hao, Tong, Lamesch, Philippe, ...
An important aspect of the development of systems biology approaches in metazoans is the characterization of expression patterns of nearly all genes predicted from genome sequences. Such...
Generation of the Brucella melitensis ORFeome Version 1.1
Dricot, Amélie, Rual, Jean-François, Lamesch, Philippe, Bertin, Nicolas, Dupuy, Denis, Hao, Tong, ...
The bacteria of the Brucella genus are responsible for a worldwide zoonosis called brucellosis. They belong to the α-proteobacteria group, as many other bacteria that live in close association with...
New genes with roles in the C. elegans embryo revealed using RNAi of ovary-enriched ORFeome clones
Fernandez, Anita G., Gunsalus, Kristin C., Huang, Jerry, Chuang, Ling-Shiang, Ying, Nancy, Liang, Hsiao-lan, ...
Several RNA interference (RNAi)-based functional genomic projects have been performed in Caenorhabditis elegans to identify genes required during embryogenesis. These studies have demonstrated that...
Firefly “femmes fatales” acquire defensive steroids (lucibufagins) from their firefly prey
Eisner, Thomas, Goetz, Michael A., Hill, David E., Smedley, Scott R., Meinwald, Jerrold
Female fireflies of the genus Photuris, the so-called firefly “femmes fatales,” prey on male fireflies of the genus Photinus. The females are able to entrap the males by faking the flash signal...
AIS is an oncogene amplified in squamous cell carcinoma
Hibi, Kenji, Trink, Barry, Patturajan, Meera, Westra, William H., Caballero, Otávia L., Hill, David E., ...
We and others recently isolated a human p53 homologue (p40/p51/p63/p73L) and localized the gene to the distal long arm of chromosome 3. Here we sought to examine the role of p40/p73L, two variants...
Berrueta, Lisbeth, Kraeft, Stine-Katherine, Tirnauer, Jennifer S., Schuyler, Scott C., Chen, Lan Bo, Hill, David E., ...
The evolutionarily conserved protein EB1 originally was identified by its physical association with the carboxyl-terminal portion of the adenomatous polyposis coli (APC) tumor suppressor protein, an...
Lamesch, Philippe, Milstein, Stuart, Hao, Tong, Rosenberg, Jennifer, Li, Ning, Sequerra, Reynaldo, ...
The first version of the Caenorhabditis elegans ORFeome cloning project, based on release WS9 of Wormbase (August 1999), provided experimental verifications for ∼55% of predicted protein-encoding...
High-Throughput Expression of C. elegans Proteins
Luan, Chi-Hao, Qiu, Shihong, Finley, James B., Carson, Mike, Gray, Rita J., Huang, Wenying, ...
Proteome-scale studies of protein three-dimensional structures should provide valuable information for both investigating basic biology and developing therapeutics. Critical for these endeavors is...
Human ORFeome Version 1.1: A Platform for Reverse Proteomics
Rual, Jean-François, Hirozane-Kishikawa, Tomoko, Hao, Tong, Bertin, Nicolas, Li, Siming, Dricot, Amélie, ...
The advent of systems biology necessitates the cloning of nearly entire sets of protein-encoding open reading frames (ORFs), or ORFeomes, to allow functional studies of the corresponding proteomes....
Toward Improving Caenorhabditis elegans Phenome Mapping With an ORFeome-Based RNAi Library
Rual, Jean-François, Ceron, Julian, Koreth, John, Hao, Tong, Nicot, Anne-Sophie, Hirozane-Kishikawa, Tomoko, ...
The recently completed Caenorhabditis elegans genome sequence allows application of high-throughput (HT) approaches for phenotypic analyses using RNA interference (RNAi). As large phenotypic data...
A First Version of the Caenorhabditis elegans Promoterome
Dupuy, Denis, Li, Qian-Ru, Deplancke, Bart, Boxem, Mike, Hao, Tong, Lamesch, Philippe, ...
An important aspect of the development of systems biology approaches in metazoans is the characterization of expression patterns of nearly all genes predicted from genome sequences. Such...
Generation of the Brucella melitensis ORFeome Version 1.1
Dricot, Amélie, Rual, Jean-François, Lamesch, Philippe, Bertin, Nicolas, Dupuy, Denis, Hao, Tong, ...
The bacteria of the Brucella genus are responsible for a worldwide zoonosis called brucellosis. They belong to the α-proteobacteria group, as many other bacteria that live in close association with...
New genes with roles in the C. elegans embryo revealed using RNAi of ovary-enriched ORFeome clones
Fernandez, Anita G., Gunsalus, Kristin C., Huang, Jerry, Chuang, Ling-Shiang, Ying, Nancy, Liang, Hsiao-lan, ...
Several RNA interference (RNAi)-based functional genomic projects have been performed in Caenorhabditis elegans to identify genes required during embryogenesis. These studies have demonstrated that...
Epstein–Barr virus and virus human protein interaction maps
Calderwood, Michael A., Venkatesan, Kavitha, Xing, Li, Chase, Michael R., Vazquez, Alexei, Holthaus, Amy M., ...
A comprehensive mapping of interactions among Epstein–Barr virus (EBV) proteins and interactions of EBV proteins with human proteins should provide specific hypotheses and a broad perspective on...
Revisiting the Saccharomyces cerevisiae predicted ORFeome
Li, Qian-Ru, Carvunis, Anne-Ruxandra, Yu, Haiyuan, Han, Jing-Dong J., Zhong, Quan, Simonis, Nicolas, ...
Accurately defining the coding potential of an organism, i.e., all protein-encoding open reading frames (ORFs) or “ORFeome,” is a prerequisite to fully understand its biology. ORFeome annotation...