4 volumes collection of published works of the author for the degree of D.Sc.
Goodfellow, M., Minnikin, David E.
"Presented at a poster session during the summer conference of the Society of Applied Bacteriology, at the University of Heriot-Watt, July, 1983"
Phetsuksiri, Benjawan, Baulard, Alain R., Cooper, Andrea M., Minnikin, David E., Douglas, James D., Besra, Gurdyal S., ...
Isoxyl (ISO), a thiourea (thiocarlide; 4,4′-diisoamyloxythiocarbanilide), demonstrated potent activity against Mycobacterium tuberculosis H37Rv (MIC, 2.5 μg/ml), Mycobacterium bovis BCG (MIC, 0.5...
Structure of a New Glycolipid from the Mycobacterium avium-Mycobacterium intracellulare Complex
Watanabe, Motoko, Ohta, Akihiro, Sasaki, Shun-ichi, Minnikin, David E.
From the lipid fraction of a freeze-dried cell mass of a strain of the Mycobacterium avium-Mycobacterium intracellulare complex, a new glycolipid was isolated and was characterized as...
A Type II Pathway for Fatty Acid Biosynthesis Presents Drug Targets in Plasmodium falciparum
Waller, Ross F., Ralph, Stuart A., Reed, Michael B., Su, Vanessa, Douglas, James D., Minnikin, David E., ...
It has long been held that the malaria parasite, Plasmodium sp., is incapable of de novo fatty acid synthesis. This view has recently been overturned with the emergence of data for the presence of a...
Kremer, Laurent, Dover, Lynn G, Carrère, Séverine, Nampoothiri, K Madhavan, Lesjean, Sarah, Brown, Alistair K, ...
Mycolic acids consist of long-chain alpha-alkyl-beta-hydroxy fatty acids that are produced by successive rounds of elongation catalysed by a type II fatty acid synthase (FAS-II). A key feature in the...
Phetsuksiri, Benjawan, Baulard, Alain R., Cooper, Andrea M., Minnikin, David E., Douglas, James D., Besra, Gurdyal S., ...
Isoxyl (ISO), a thiourea (thiocarlide; 4,4′-diisoamyloxythiocarbanilide), demonstrated potent activity against Mycobacterium tuberculosis H37Rv (MIC, 2.5 μg/ml), Mycobacterium bovis BCG (MIC, 0.5...
Structure of a New Glycolipid from the Mycobacterium avium-Mycobacterium intracellulare Complex
Watanabe, Motoko, Ohta, Akihiro, Sasaki, Shun-ichi, Minnikin, David E.
From the lipid fraction of a freeze-dried cell mass of a strain of the Mycobacterium avium-Mycobacterium intracellulare complex, a new glycolipid was isolated and was characterized as...
A Type II Pathway for Fatty Acid Biosynthesis Presents Drug Targets in Plasmodium falciparum
Waller, Ross F., Ralph, Stuart A., Reed, Michael B., Su, Vanessa, Douglas, James D., Minnikin, David E., ...
It has long been held that the malaria parasite, Plasmodium sp., is incapable of de novo fatty acid synthesis. This view has recently been overturned with the emergence of data for the presence of a...
Kremer, Laurent, Dover, Lynn G, Carrère, Séverine, Nampoothiri, K Madhavan, Lesjean, Sarah, Brown, Alistair K, ...
Mycolic acids consist of long-chain alpha-alkyl-beta-hydroxy fatty acids that are produced by successive rounds of elongation catalysed by a type II fatty acid synthase (FAS-II). A key feature in the...
Hershkovitz, Israel, Donoghue, Helen D., Minnikin, David E., Besra, Gurdyal S., Lee, Oona Y-C., Gernaey, Angela M., ...
Bhatt, Apoorva, Brown, Alistair K., Singh, Albel, Minnikin, David E., Besra, Gurdyal S.
Mycolic acids are essential components of the mycobacterial cell wall. In this study, we show that a gene encoding a reductase involved in the final step of mycolic acid biosynthesis can be deleted...