David E. Noakes

The effect of pre- and peri-conceptional undernutrition on arterial function in adult female sheep are vascular bed dependent (2009)

Torrens, Christopher, Snelling, Tristram H., Chau, Ryan, Shanmuganathan, Meena, Cleal, Jane K., Poore, Kirsten R., ...

The nutritional environment during development and even prior to conception may contribute to cardiovascular risk. In mature adult female sheep, we investigated the effect of preconceptional and...

The effect of maternal undernutrition in early gestation on gestation length and fetal and postnatal growth in sheep (2007)

Cleal, Jane K., Poore, Kirsten R., Newman, James P., Noakes, David E., Hanson, Mark A., Green, Lucy R.

In utero undernutrition in humans may result in cardiovascular (CV), metabolic, and growth adaptations. In sheep, maternal nutrient restriction during pregnancy, without effects on fetal or birth...

Mismatched pre- and postnatal nutrition leads to cardiovascular dysfunction and altered renal function in adulthood (2007)

Cleal, Jane K., Poore, Kirsten R., Boullin, Julian P., Khan, Omar, Chau, Ryan, Hambidge, Oliver, ...

The early life environment has long-term implications for the risk of developing cardiovascular (CV) disease in adulthood. Fetal responses to changes in maternal nutrition may be of immediate benefit...

Mismatched pre- and postnatal nutrition leads to cardiovascular dysfunction and altered renal function in adulthood (2007)

Cleal, Jane K., Poore, Kirsten R., Boullin, Julian P., Khan, Omar, Chau, Ryan, Hambidge, Oliver, ...

The early life environment has long-term implications for the risk of developing cardiovascular (CV) disease in adulthood. Fetal responses to changes in maternal nutrition may be of immediate benefit...

Nutritional challenges during development induce sex-specific changes in glucose homeostasis in the adult sheep (2007)

Poore, Kirsten R., Cleal, Jane K., Newman, James P., Boullin, Julian P., Noakes, David E., Hanson, Mark A., ...

The early-life environment has implications for risk of adult-onset diseases, such as glucose intolerance, insulin insensitivity, and obesity, effects that may occur with or without reduced birth...

Nutritional challenges during development induce sex-specific changes in glucose homeostasis in the adult sheep (2007)

Poore, Kirsten R., Cleal, Jane K., Newman, James P., Boullin, Julian P., Noakes, David E., Hanson, Mark A., ...

The early-life environment has implications for risk of adult-onset diseases such as glucose intolerance, insulin insensitivity and obesity, effects which may occur with or without reduced birth...

Effects of pre-natal and early post-natal undernutrition on adult internal thoracic artery function (2005)

Khan, Omar A., Torrens, Christopher, Noakes, David E., Poston, Lucilla, Hanson, Mark A., Green, Lucy R., ...

Objective: Previous studies in humans and animals have suggested that undernutrition in utero and in early post-natal life may lead to altered vascular function in a number of peripheral arteries. We...

Effect of nutritional restriction in early pregnancy on isolated femoral artery function in mid-gestation fetal sheep (2003)

Nishina, Hidenori, Green, Lucy R., McGarrigle, Hugh H.G., Noakes, David E., Poston, Lucilla, Hanson, Mark A.

Unbalanced maternal nutrition affects fetal endocrine and cardiovascular systems, sometimes accompanied by changes in growth, although this is usually in late gestation. We determined the effect of...

Undernutrition during the first half of gestation increases the predominance of fetal tissue in late-gestation ovine placentomes (2001)

Steyn, Clare, Hawkins, Paul, Saito, Tsukuru, Noakes, David E., Kingdom, John C., Hanson, Mark A.

Objective: To investigate, in sheep, the effects of maternal undernutrition during the first half of pregnancy on placental growth and development and fetal growth. Study design: Six ewes (R) were...

Mismatched pre- and postnatal nutrition leads to cardiovascular dysfunction and altered renal function in adulthood

Cleal, Jane K., Poore, Kirsten R., Boullin, Julian P., Khan, Omar, Chau, Ryan, Hambidge, Oliver, ...

The early life environment has long-term implications for the risk of developing cardiovascular (CV) disease in adulthood. Fetal responses to changes in maternal nutrition may be of immediate benefit...

Effect of nutritional restriction in early pregnancy on isolated femoral artery function in mid-gestation fetal sheep

Nishina, Hidenori, Green, Lucy R, McGarrigle, Hugh H G, Noakes, David E, Poston, Lucilla, Hanson, Mark A

Unbalanced maternal nutrition affects fetal endocrine and cardiovascular systems, sometimes accompanied by changes in growth, although this is usually in late gestation. We determined the effect of...