David Gonzalez

Transcriptional analysis of the jamaicamide gene cluster from the marine cyanobacterium Lyngbya majusculaand identification of possible regulatory proteins (2009)

Jones, Adam C, Gerwick, Lena, Gonzalez, David, Dorrestein, Pieter C, Gerwick, William H

Abstract Background The marine cyanobacterium Lyngbya majuscula is a prolific producer of bioactive secondary metabolites. Although biosynthetic gene clusters encoding several of these compounds have...

The Fast Declining Type Ia Supernova 2003gs, and Evidence for a Significant Dispersion in Near-Infrared Absolute Magnitudes of Fast Decliners at Maximum Light (2009)

Krisciunas, Kevin, Marion, G. H., Suntzeff, Nicholas B., Blanc, Guillaume, Bufano, Filomena, Candia, Pablo, ...

We obtained optical photometry of SN 2003gs on 49 nights, from 2 to 494 days after T(B_(max)). We also obtained near-IR photometry on 21 nights. SN 2003gs was the first fast declining Type Ia SN that...

The fast declining Type Ia supernova 2003gs, and evidence for a significant dispersion in near-infrared absolute magnitudes of fast decliners at maximum light (2009)

Krisciunas, Kevin, Marion, G. H., Suntzeff, Nicholas B., Blanc, Guillaume, Bufano, Filomena, Candia, Pablo, ...

We obtained optical photometry of SN 2003gs on 49 nights, from 2 to 494 days after T(B_max). We also obtained near-IR photometry on 21 nights. SN 2003gs was the first fast declining Type Ia SN that...

Do the photometric colors of Type II-P Supernovae allow accurate determination of host galaxy extinction? (2008)

Krisciunas, Kevin, Hamuy, Mario, Suntzeff, Nicholas B., Espinoza, Juan, Gonzalez, David, Gonzalez, Luis, ...

We present infrared photometry of SN 1999em, plus optical photometry, infrared photometry, and optical spectroscopy of SN 2003hn. Both objects were Type II-P supernovae. The V-[RIJHK] color curves of...

Gene mapping and expression analysis of 16q loss of heterozygosity identifies WWOX and CYLD as being important in determining clinical outcome in multiple myeloma (2007)

Jenner, Matthew W., Leone, Paola E., Walker, Brian A., Ross, Fiona M., Johnson, David C., Gonzalez, David, ...

We performed fluorescent in situ hybridization (FISH) for 16q23 abnormalities in 861 patients with newly diagnosed multiple myeloma and identified deletion of 16q [del(16q)] in 19.5%. In 467 cases in...

Gene mapping and expression analysis of 16q loss of heterozygosity identifies WWOX and CYLD as being important in determining clinical outcome in multiple myeloma (2007)

Jenner, Matthew W., Leone, Paola E., Walker, Brian A., Ross, Fiona M., Johnson, David C., Gonzalez, David, ...

We performed FISH for 16q23 abnormalities in 861 patients with newly diagnosed multiple myeloma and identified del(16q) in 19.5%. In 467 cases in which demographic and survival data were available,...

A novel hybrid carbon material (2007)

Nasibulin, Albert G., Pikhitsa, Peter V., Jiang, Hua, Brown, David P., Krasheninnikov, Arkady V., Anisimov, Anton S., ...

Both fullerenes and single-walled carbon nanotubes (SWNTs) exhibit many advantageous properties(1). Despite the similarities between these two forms of carbon, there have been very few attempts to...

LETTERS A novel hybrid carbon material (2007)

Albert G. Nasibulin, Peter V. Pikhitsa, David P. Brown, Arkady V. Krasheninnikov, Anton S. Anisimov, Paula Queipo, ...

Both fullerenes and single-walled carbon nanotubes (SWNTs) exhibit many advantageous properties 1. Despite the similarities between these two forms of carbon, there have been very few attempts to...

The Type Ia supernova 2004S, a clone of SN 2001el, and the optimal photometric bands for extinction estimation (2006)

Krisciunas, Kevin, Garnavich, Peter M., Stanishev, Vallery, Suntzeff, Nicholas B., Prieto, Jose Luis, Espinoza, Juan, ...

We present optical (UBVRI) and near-infrared (YJHK) photometry of the normal Type Ia supernova 2004S. We also present eight optical spectra and one near-IR spectrum of SN 2004S. The light curves and...

Optical and near-infrared observations of the peculiar Type la supernova 1999ac (2006)

Phillips, Mark M., Krisciunas, Kevin, Suntzeff, Nicholas B., Abraham, R. G., Beckett, M. G., Bonati, Marco, ...

We present 39 nights of optical photometry, 34 nights of IR photometry, and 4 nights of optical spectroscopy of the Type la supernova 1999ac. This supernova was discovered 2 weeks before maximum...

Optical and near-infrared observations of the peculiar Type la supernova 1999ac (2006)

Phillips, Mark M., Krisciunas, Kevin, Suntzeff, Nicholas B., Abraham, R. G., Beckett, M. G., Bonati, Marco, ...

We present 39 nights of optical photometry, 34 nights of IR photometry, and 4 nights of optical spectroscopy of the Type la supernova 1999ac. This supernova was discovered 2 weeks before maximum...

Optical and near-infrared observations of the peculiar Type la supernova 1999ac (2006)

Phillips, Mark M., Krisciunas, Kevin, Suntzeff, Nicholas B., Abraham, R. G., Beckett, M. G., Bonati, Marco, ...

We present 39 nights of optical photometry, 34 nights of IR photometry, and 4 nights of optical spectroscopy of the Type la supernova 1999ac. This supernova was discovered 2 weeks before maximum...

Status of chromosome 13 in multiple myeloma: Integrated approach using SNP mapping array and gene expression array (2005)

Leone, Paola E., Walker, Brian A., Gonzalez, David, Jenner, Matthew, Ross, Fiona M., Li, Cheng, ...

Deletions on chromosome 13 are thought to be one of the most important prognostic features in Multiple Myeloma (MM). The biology underlying this is, however, uncertain. Chromosome 13 abnormalities...

Insights into the basis of chromosomal imbalances during the clonal evolution of multiple myeloma using SNP array analysis (2005)

Walker, Brian A., Leone, Paola E., Jenner, Matthew, Gonzalez, David, Ross, Fiona M., Li, Cheng, ...

On the basis of hyperdiploidy, often involving trisomies of chromosomes 3, 5, 7, 9, 11, 15, 19 and 21, and chromosomal translocations multiple myeloma (MM) can be separated into two broad groups....

Identification of collaborating oncogeneic events leading to disease progression in myeloma cases with a t(4;14) and t(11;14) using SNP and gene expression arrays (2005)

Jenner, Matthew W., Walker, Brian A., Leone, Paola E., Gonzalez, David, Ross, Fiona M., Li, Cheng, ...

Immunoglobulin heavy chain translocations are an initiating genetic event in the pathogenesis of 50% of multiple myeloma cases. The t(4;14) and t(11;14) translocations each occur in approximately 15%...

Insights into the basis of chromosomal imbalances during the clonal evolution of multiple myeloma using SNP array analysis (2005)

Walker, Brian A., Leone, Paola E., Jenner, Matthew, Gonzalez, David, Ross, Fiona M., Li, Cheng, ...

On the basis of hyperdiploidy, often involving trisomies of chromosomes 3, 5, 7, 9, 11, 15, 19 and 21, and chromosomal translocations multiple myeloma (MM) can be separated into two broad groups....

Photooxidation of Polypropylene/Montmorillonite Nanocomposites. 2. Interactions with Antioxidants. (2005)

Gardette, Jean-Luc, Morlat-Therias, Sandrine, Mailhot, Bénédicte, Gonzalez, David

The influence of stabilizing additives on the photooxidation of polypropylene/montmorillonite (PP/ MMt) nanocomposites exposed to UV light was studied. Two différent stabilizers were used, a...

Photooxidation of Polypropylene/Montmorillonite Nanocomposites. 2. Interactions with Antioxidants. (2005)

Gardette, Jean-Luc, Morlat-Therias, Sandrine, Mailhot, Bénédicte, Gonzalez, David

The influence of stabilizing additives on the photooxidation of polypropylene/montmorillonite (PP/ MMt) nanocomposites exposed to UV light was studied. Two différent stabilizers were used, a...

Poster sessions. Identification of collaborating oncogeneic events leading to disease progression in myeloma cases with a t(4;14) and t(11;14) using SNP and gene expression arrays (2005)

Jenner, Matthew W., Walker, Brian A., Leone, Paola E. Leone, Gonzalez, David, Ross, Fiona M., Li, Cheng, ...

Immunoglobulin heavy chain translocations are an initiating genetic event in the pathogenesis of 50% of multiple myeloma cases. The t(4;14) and t(11;14) translocations each occur in approximately 15%...

Cytomegalovirus Hepatitis During Pregnancy (1995)

Ying Chan, Maria Kean-Chong, David Gonzalez, Joseph Apuzzio

Background: Although cytomegalovirus (CMV) is an uncommon cause of viral hepatitis during pregnancy, a definitive diagnosis is important because of the potential for congenital CMV. In the case...

Application of Self-Quenched JH Consensus Primers for Real-Time Quantitative PCR of IGH Gene to Minimal Residual Disease Evaluation in Multiple Myeloma

Martinez-Lopez, Joaquin, Martinez-Sanchez, Pilar, Garcia-Sanz, Ramon, Sarasquete, Maria Eugenia, Ayala, Rosa, Gonzalez, Marcos, ...

Monitoring multiple myeloma patients for relapse requires sensitive methods to measure minimal residual disease and to establish a more precise prognosis. The present study aimed to standardize a...

Cytomegalovirus Hepatitis During Pregnancy

Chan, Ying, Kean-Chong, Maria, Gonzalez, David, Apuzzio, Joseph

Background: Although cytomegalovirus (CMV) is an uncommon cause of viral hepatitis during pregnancy, a definitive diagnosis is important because of the potential for congenital CMV. In the case...

Biosynthetic origin of natural products isolated from marine microorganism–invertebrate assemblages

Simmons, T. Luke, Coates, R. Cameron, Clark, Benjamin R., Engene, Niclas, Gonzalez, David, Esquenazi, Eduardo, ...

In all probability, natural selection began as ancient marine microorganisms were required to compete for limited resources. These pressures resulted in the evolution of diverse genetically encoded...

Discovery of a widely distributed toxin biosynthetic gene cluster

Lee, Shaun W., Mitchell, Douglas A., Markley, Andrew L., Hensler, Mary E., Gonzalez, David, Wohlrab, Aaron, ...

Bacteriocins represent a large family of ribosomally produced peptide antibiotics. Here we describe the discovery of a widely conserved biosynthetic gene cluster for the synthesis of thiazole and...

MMSET deregulation affects cell cycle progression and adhesion regulons in t(4;14) myeloma plasma cells

Brito, Jose L.R., Walker, Brian, Jenner, Matthew, Dickens, Nicholas J., Brown, Nicola J.M., Ross, Fiona M., ...

The t(4;14) translocation leads to the simultaneous overexpression of two genes, FGFR3 and MMSET, in myeloma plasma cells. The findings of this study suggest that MMSET is implicated in the...

Differential roles of migratory and resident DCs in T cell priming after mucosal or skin HSV-1 infection

Lee, Heung Kyu, Zamora, Melodie, Linehan, Melissa M., Iijima, Norifumi, Gonzalez, David, Haberman, Ann, ...

Although mucosal surfaces represent the main portal of entry for pathogens, the mechanism of antigen presentation by dendritic cells (DCs) that patrol various mucosal tissues remains unclear....