David Hughes

Publication List Details

Period

1843 - 2009

Number

127

Co-Authors

Stratagem – a methodology and computer-based tool for strategic regeneration (2009)

David Hughes

This paper describes the research and development, supported by the UK Department of Trade and Industry, DTI, of a novel approach to the implementation of manufacturing best practice. The approach...

Stratagem – a methodology and computer-based tool for strategic regeneration (2009)

David Hughes

This paper describes the research and development, supported by the UK Department of Trade and Industry, DTI, of a novel approach to the implementation of manufacturing best practice. The approach...

The SCUBA HAlf Degree Extragalactic Survey – VI. 350-μm mapping of submillimetre galaxies (2008)

Coppin, Kristen, Halpern, Mark, Scott, Douglas, Borys, Colin, Dunlop, James S., Dunne, Loretta, ...

A follow-up survey using the Submillimetre High-Angular Resolution Camera (SHARC-II) at 350 μm has been carried out to map the regions around several 850-μm-selected sources from the Submillimetre...

Lymphatics and bone (2008)

Edwards, James, Williams, Kelly, Kindblom, Lars, Meis-Kindblom, Jeanne, Hogendoorn, Pancras, Hughes, David, ...

There is controversy regarding whether lymphatic vessels are present or absent in bone. Although lymphangiomas have been described in bone, lymphatic vessels have not been identified morphologically...

The SCUBA HAlf Degree Extragalactic Survey (SHADES) -- VI. 350 micron mapping of submillimetre galaxies (2007)

Coppin, Kristen, Halpern, Mark, Scott, Douglas, Borys, Colin, Dunlop, James, Dunne, Loretta, ...

A follow-up survey using the Submillimetre High-Angular Resolution Camera (SHARC-II) at 350 microns has been carried out to map the regions around several 850 micron-selected sources from the...

Context and change in Japanese music (2007)

Tokita, Alison McQueen, Hughes, David

Although Japan is often portrayed as culturally and ethnically highly homogeneous, its music culture has long been extremely diverse, especially so with modernization and globalization. Thus we begin...

Context and change in Japanese music (2007)

Tokita, Alison McQueen, Hughes, David

Although Japan is often portrayed as culturally and ethnically highly homogeneous, its music culture has long been extremely diverse, especially so with modernization and globalization. Thus we begin...

6-azapyrimidine-2'-deoxy-4'-thionucleosides: antiviral agents against TK+ and TK- HSV and VZV strains (2004)

Hughes, David, Hursthouse, Mike, Simons, Claire

The synthesis of a series of novel 1-(2-deoxy-4-thio-beta-D-erythro-pentofuranosyl)-(6-azapyrimidine) nucleosides is described. X-ray crystallographic data of the thymidine derivative allowed...

Acetyl-CoA carboxylase {alpha} gene and breast cancer susceptibility (2004)

Sinilnikova, Olga M., Ginolhac, Sophie M., Magnard, Clémence, Léoné, Mélanie, Anczukow, Olga, Hughes, David, ...

The identification of an interaction between BRCA1 and acetyl-CoA carboxylase α (ACCα), a key enzyme in lipid synthesis, led us to investigate the role of ACCα in breast cancer development, where...

Just a Breath of Fresh Air in an Industrial Landscape? The Preston Open Air School in 1926: A School Medical Service Insight (2004)

Hughes, David

Historians who have studied the early twentieth-century development of the open air school movement for physically debilitated children have largely maintained that the therapeutic benefit of the...

A Heavenly Example of Scale Free Networks and Self-Organized Criticality (2003)

Paczuski, Maya, Hughes, David

The sun provides an explosive, heavenly example of self-organized criticality. Sudden bursts of intense radiation emanate from rapid rearrangements of the magnetic field network in the corona....

Scale-Free Magnetic Networks: Comparing Observational Data with a Self-Organizing Model of the Coronal Field (2003)

Hughes, David, Paczuski, Maya

We propose that the coronal magnetic field, linking concentrations on the photosphere through an interwoven web of flux, embodies a scale-free network. It arises from a self-organized critical...

CD20-induced lymphoma cell death is independent of both caspases and its redistribution into triton X-100 insoluble membrane rafts (2003)

Chan, H.T. Claude, Hughes, David, French, Ruth R., Tutt, Alison L., Walshe, Claire A., Teeling, Jessica L., ...

Rituximab is routinely used for the treatment of neoplasia, although the mechanism of action remains uncertain. In the current study, CD20-induced apoptosis was investigated with a panel of anti-CD20...

CD20-induced lymphoma cell death is independent of both caspases and its redistribution into Triton X-100 insoluble membrane rafts (2003)

Chan, H.T.C., Hughes, David, French, Ruth.R., Tutt, Alison.L., Walshe, Claire.A., Teeling, Jessica.L., ...

Rituximab is routinely used for the treatment of neoplasia, although the mechanism of action remains uncertain. In the current study, CD20-induced apoptosis was investigated with a panel of anti-CD20...

Deep radio imaging of the SCUBA 8-mJy survey fields: sub-mm source identifications and redshift distribution (2002)

Ivison, Rob, Greve, Thomas, Smail, Ian, Dunlop, James, Roche, Nathan, Scott, Susie, ...

The SCUBA 8-mJy survey is the largest submm extragalactic mapping survey undertaken to date, centred on the Lockman Hole and ELAIS N2 regions. Here, we present new 1.4-GHz imaging of the depth and...

Behavioral-Performance Effects from a High-Neutron, Low-Gamma Radiation Pulse Exposure. (2002)

Brown,G. Carroll, Yochmowitz,Michael G., Hardy,Kenneth A., Hughes,David, Yarbrough,Billy

A self-paced, 3-light, 3-lever discrete avoidance behavioral task was initiated to study the behavioral performance effects of a high-neutron, low-gamma radiation pulse exposure (550-650 rads, 5.5:1...

Changes in young people's social networks and welfare reform in Australia (2002)

Rob Strathdee, David Hughes

Recent proposals for social welfare reform in Australia are predicated on the assumption that passive welfare systems have eroded pro-work attitudes and values. Staying on welfare is believed to have...

Changes in young people's social networks and welfare reform in Australia (2002)

Rob Strathdee, David Hughes

Recent proposals for social welfare reform in Australia are predicated on the assumption that passive welfare systems have eroded pro-work attitudes and values. Staying on welfare is believed to have...

Large Scale Structures, Symmetry, and Universality in Sandpiles (2001)

Hughes, David, Paczuski, Maya

We introduce a sandpile model where, at each unstable site, all grains are transferred randomly to downstream neighbors. The model is local and conservative, but not Abelian. This does not appear to...

Mega trends: I. Consumer well-being and health Elektronische Daten (2001)

Hughes, David

Am Kopf des Titelblattes: Imperial College of Science, Technology and Medicine

Anhydrous magnesium chloride (2000)

Gregory John Sheehan, Fook-Sin Wong, Michael Matthew Hourn, Manabu Kodama, David Hughes

Production of high quality anhydrous magnesium chloride for making magnesium metal in an electrolytic cell was achieved. This research culminated in the successful operation of a $150 million...

Anhydrous magnesium chloride (2000)

Gregory John Sheehan, Fook-Sin Wong, Michael Matthew Hourn, Manabu Kodama, David Hughes

Production of high quality anhydrous magnesium chloride for making magnesium metal in an electrolytic cell was achieved. This research culminated in the successful operation of a $150 million...

Automated Preparation of Digital Topographic Data, (1998)

Gaines,Richard, Hughes,David, Reiss,Royce, Schneider,Philip A. D.

The report contains descriptions and documentation for four related computer programs developed to completely automate the process of preparing digital topographic data (DTD) for applications such as...

DBSSG Predictable Real-Time Information Systems Task Group. (1998)

Fisher, Donna, Fortier, Paul, Hughes, David, Roark, Mayford

This report is the result of the study conducted by the American National Standards Institute (ANSI), Accredited Standards Committee (ASC), X3, Operational Management Committee (OMC), Database...

Unveiling Dust-enshrouded Star Formation in the Early Universe: a Sub-mm Survey of the Hubble Deep Field (1998)

Hughes, David, Serjeant, Steve, Dunlop, James, Rowan-Robinson, Michael, Blain, Andrew, Mann, Robert G., ...

The advent of sensitive sub-mm array cameras now allows a proper census of dust-enshrouded massive star-formation in very distant galaxies, previously hidden activity to which even the faintest...

Dust, gas and the evolutionary status of the radio galaxy, 8C1435+635, at z = 4.25 (1997)

Ivison, Rob, Dunlop, James, Hughes, David, Archibald, Elese, Stevens, Jason, Holland, Wayne, ...

We present the results of new rest-frame far-IR observations of the z = 4.25 radio galaxy, 8C1435+635, which not only confirm that it contains an enormous quantity of dust (as first inferred from its...

High-redshift radio galaxies and quasars at sub-millimetre wavelengths: assessing their evolutionary status (1997)

Hughes, David, Dunlop, J. S., Rawlings, Steve

We present new results of a study of the sub-millimetre continuum emission from a sample of 9 radio galaxies and 4 radio-quiet quasars at redshifts $z = 0.75 - 4.26$. The observations were made at...

A review of the economic analysis of obesity (1997)

McGuire, Alistair, Hughes, David

There are indications that the treatment costs arising from obesity are significant. However, the cost-of-illness studies undertaken to date also highlight two other important points. First, the cost...

Thought ware : Change the Thinking and the Organization Will Change Itself (1997)

Kirby, J. Philip, Hughes, David

El pensamiento es el antecedente de la acción. Los pensamientos de las personas son la base de todo lo que ellas hacen. La suma de pensamientos individuales y su interrelación entre sí se...

Thought ware : Change the Thinking and the Organization Will Change Itself / J.P. Kirby, D. Hughes. (1997)

Kirby, J. Philip, Hughes, David

El pensamiento es el antecedente de la acción. Los pensamientos de las personas son la base de todo lo que ellas hacen. La suma de pensamientos individuales y su interrelación entre sí se...

The optimal use of hospital capacity in the presence of stochastic demand and output heterogeneity. (1997)

Hughes, David.

Thesis (Ph. D.)--Wolverhampton Business School, Management Research Centre, 1997.

Using new submillimetre surveys to identify the evolutionary status of high-z galaxies (1997)

David Hughes, David Hughes, James Dunlop, James Dunlop

In this paper we briefly describe a `key ' survey at submm wavelengths which we are currently conducting to address some of the most important questions in cosmology- how, at what epoch and over...

Do quasi-markets evolve? Institutional analysis and the NHS (1997)

Hughes, David, Griffiths, Lesley, McHale, Jean V.

Institutional analysis offers a promising opportunity for theoretical cross-fertilisation between economics and sociology. Neo-institutional economics argues that organisations gravitate towards...

A review of the economic analysis of obesity (1997)

Hughes, David, McGuire, A

There are indications that the treatment costs arising from obesity are significant. However, the cost-of-illness studies undertaken to date also highlight two other important points. First, the cost...

The cost-effectiveness of family planning service provision (1996)

McGuire, Alistair, Hughes, David

BACKGROUND: Family planning services are amongst the most highly utilized services in the National Health Service. There have, however, been few empirical studies of the costeffectiveness of these...

Patient charges and the utilisation of NHS prescription medicines: some estimates using the cointegration procedure (1995)

McGuire, Alistair, Hughes, David

Since the inception of the NHS, user charges have been present for prescription medication. However since 1968 there has been a steady increase in this charge, particularly notable during the 1980s....

Econometric analysis of health care expenditures: can positive analysis help answer normative questions? (1993)

McGuire, Alistair, Parkin, David, Hughes, David, Gerard, Karen

The size of national health care expenditure is an important research and policy issue. This paper reviews theoretical and empirical analyses of an implied optimal size for a health sector. Various...

Minerva : An Event Based Model For Extensible Network Management (1993)

David Hughes, Wu Zheng Da

The goal of the work outlined within this paper is to provide a Network Management System (NMS) capable of supporting "non-typical" environments. It is viewed that no NMS developer can...

Screening for mutations in the open reading frame and promoter of the {beta}-amyloid precursor protein gene in familial Alzheimer's disease: identification of a further family with APP717 Val->lle (1992)

Fidani, Liana, Rooke, Karen, Chartier-Harlin, Marie-Christine, Hughes, David, Tanzi, Rudi, Mullan, Mike, ...

Following the identification of mutations in the β-amyloid precursor protein (APP) gene in familial, early onse Alzheimer's disease (AD), we have developed a screening protocol using single strand...

Costing Consultations in General practice: Towards a Standardized Method (1991)

HUGHES, DAVID

The cost of a consultation with a general practitioner forms an integral part of many economic evaluations. If resources are to be allocated efficiently it is necessary to provide accurate costings....

Ethanol fermentation by novel thermotolerant yeasts (1985)

Hughes, David (David Bruce)

Typescript (word-processed) Bibliography: leaves 115-122.

Hepatitis or inflammation of the liver /--by David Hughes. (1874)

Hughes, David.

Handwritten thesis submitted in partial fulfillment of the requirements of the degree of M.D.

Interaction between the Product of the Breast Cancer Susceptibility Gene BRCA2 and DSS1, a Protein Functionally Conserved from Yeast to Mammals

Marston, Nicola J., Richards, William J., Hughes, David, Bertwistle, David, Marshall, Christopher J., Ashworth, Alan

Germ line mutations in the breast cancer susceptibility gene BRCA2 predispose to early-onset breast cancer, but the function of the nuclear protein encoded by the gene is ill defined. Using the yeast...

Interaction between the Product of the Breast Cancer Susceptibility Gene BRCA2 and DSS1, a Protein Functionally Conserved from Yeast to Mammals

Marston, Nicola J., Richards, William J., Hughes, David, Bertwistle, David, Marshall, Christopher J., Ashworth, Alan

Germ line mutations in the breast cancer susceptibility gene BRCA2 predispose to early-onset breast cancer, but the function of the nuclear protein encoded by the gene is ill defined. Using the yeast...

Consultation length and outcome in two group general practices

Hughes, David

Two group general practices were located which, while similar in a number of important respects, differed in the number of appointment consultations arranged per hour, and data was collected to see...

Do Quasi-markets Evolve? Institutional Analysis and the NHS.

Hughes, David, Griffiths, Lesley, McHale, Jean V

Institutional analysis offers a promising opportunity for theoretical cross-fertilization between economics and sociology. Neo-institutional economics argues that organizations gravitate towards...

Positive Selection in East Asians for an EDAR Allele that Enhances NF-κB Activation

Bryk, Jarosław, Hardouin, Emilie, Pugach, Irina, Hughes, David, Strotmann, Rainer, Stoneking, Mark, ...

Genome-wide scans for positive selection in humans provide a promising approach to establish links between genetic variants and adaptive phenotypes. From this approach, lists of hundreds of candidate...

Positive selection in East Asians for an EDAR allele that enhances NF-kappaB activation

Bryk, Jarosław, Hardouin, Emilie, Pugach, Irina, Hughes, David, Strotmann, Rainer, Stoneking, Mark, ...

Genome-wide scans for positive selection in humans provide a promising approach to establish links between genetic variants and adaptive phenotypes. From this approach, lists of hundreds of candidate...