David I. Ellis

A GC-TOF-MS study of the stability of serum and urine metabolomes during the UK Biobank sample collection and preparation protocols (2008)

Dunn, Warwick B, Broadhurst, David, Ellis, David I, Brown, Marie, Halsall, Anthony, O’Hagan, Steven, ...

Background The stability of mammalian serum and urine in large metabolomic investigations is essential for accurate, valid and reproducible studies. The stability of mammalian serum and urine, either...

From phenotype to genotype: whole tissue profiling for plant breeding (2007)

Goodacre, Royston, Roberts, L. A., Ellis, David I., Thorogood, D., Reader, S. M., Ougham, H. J., ...

Keywords: artificial neural network - hierarchical cluster analysis - discriminant function - Lolium - principal components - Triticum

Metabolomic approaches reveal that phosphatidic and phosphatidyl glycerol phospholipids are major discriminatory non-polar metabolites in responses by Brachypodium distachyon to challenge by Magnaporthe grisea (2006)

Allwood, J. William, Ellis, David I., Heald, Jim K., Goodacre, Royston, Mur, Luis A. J.

Metabolomic approaches were used to elucidate some key metabolite changes occurring during interactions of Magnaporthe grisea– the cause of rice blast disease – with an alternate host,...

Metabolomic approaches reveal that phosphatidic and phosphatidyl glycerol phospholipids are major discriminatory non-polar metabolites in responses by Brachypodium distachyon to challenge by Magnaporthe grisea. (2006)

Allwood, J. William, Ellis, David I., Heald, Jim K., Goodacre, Royston, Mur, Luis A. J.

Metabolomic approaches were used to elucidate some key metabolite changes occurring during interactions of Magnaporthe grisea– the cause of rice blast disease – with an alternate host,...

Functional Genomics Via Metabolic Footprinting: Monitoring Metabolite Secretion by Escherichia Coli Tryptophan Metabolism Mutants Using FT–IR and Direct Injection Electrospray Mass Spectrometry (2006)

Naheed N. Kaderbhai, David I. Broadhurst, David I. Ellis, Royston Goodacre, Douglas B. Kell

We sought to test the hypothesis that mutant bacterial strains could be discriminated from each other on the basis of the metabolites they secrete into the medium (their ‘metabolic...

Huntington disease patients and transgenic mice have similar pro-catabolic serum metabolite profiles (2006)

Underwood, Benjamin R., Broadhurst, David, Dunn, Warwick B., Ellis, David I., Michell, Andrew W., Vacher, Coralie, ...

There has been considerable progress recently towards developing therapeutic strategies for Huntington's disease (HD), with several compounds showing beneficial effects in transgenic mouse models....

Huntington disease patients and transgenic mice have similar pro-catabolic serum metabolite profiles (2006)

Underwood, Benjamin R., Broadhurst, David, Dunn, Warwick B., Ellis, David I., Michell, Andrew W., Vacher, Coralie, ...

There has been considerable progress recently towards developing therapeutic strategies for Huntington's disease (HD), with several compounds showing beneficial effects in transgenic mouse models....

Rapid identification of closely related muscle foods by vibrational spectroscopy and machine learning (2005)

Ellis, David I., Broadhurst, David, Clarke, S. J., Goodacre, Royston

Muscle foods are an integral part of the human diet and during the last few decades consumption of poultry products in particular has increased significantly. It is important for consumers, retailers...

From genomes to systems (2004)

Ellis, David I, O'Hagan, Steve, Dunn, Warwick B, Brown, Marie, Vaidyanathan, Seetharaman

Abstract A report on the 2nd Conference of the Consortium for Post-Genome Science (CPGS) 'Genomes to Systems', Manchester, UK, 1-3 September 2004.

Rapid and quantitative detection of the microbial spoilage of beef by Fourier transform infrared spectroscopy and machine learning (2004)

Ellis, David I., Broadhurst, David, Goodacre, Royston

Beef is a commercially important and widely consumed muscle food and central to the protein intake of many societies. In the food industry no technology exists for the rapid and accurate detection of...

Functional Genomics via Metabolic Footprinting: Monitoring Metabolite Secretion by Escherichia coli Tryptophan Metabolism Mutants Using FT–IR and Direct Injection Electrospray Mass Spectrometry (2003)

Naheed N. Kaderbhai, David I. Broadhurst, David I. Ellis, Royston Goodacre, Douglas B. Kell

We sought to test the hypothesis that mutant bacterial strains could be discriminated from each other on the basis of the metabolites they secrete into the medium (their ‘metabolic footprint’),...

Rapid and quantitative detection of the microbial spoilage of muscle foods: current status and future trends (2002)

Ellis, David I., Goodacre, Royston

The requirement for real-time monitoring in the modern and highly automated food processing environment has stimulated research into rapid microbiological testing. This review will concentrate on the...

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, June 2002, p. 2822--2828 Vol. 68, No. 6 0099-2240/02/$04.000 DOI: 10.1128/AEM.68.6.2822--2828.2002 (2002)

Copyright American Society, David I. Ellis, David Broadhurst, Douglas B. Kell, Jem J. Rowl, Royston Goodacre

showing that at levels of 10 bacteriag the main biochemical indicator of spoilage was the onset of proteolysis. Thus, using FT-IR we were able to acquire a metabolic snapshot and quantify,...

Rapid and Quantitative Detection of the Microbial Spoilage of Meat by Fourier Transform Infrared Spectroscopy and Machine Learning

Ellis, David I., Broadhurst, David, Kell, Douglas B., Rowland, Jem J., Goodacre, Royston

Fourier transform infrared (FT-IR) spectroscopy is a rapid, noninvasive technique with considerable potential for application in the food and related industries. We show here that this technique can...

From genomes to systems

Ellis, David I, O'Hagan, Steve, Dunn, Warwick B, Brown, Marie, Vaidyanathan, Seetharaman

A report on the 2nd Conference of the Consortium for Post-Genome Science (CPGS) 'Genomes to Systems', Manchester, UK, 1-3 September 2004.

Rapid and Quantitative Detection of the Microbial Spoilage of Meat by Fourier Transform Infrared Spectroscopy and Machine Learning

Ellis, David I., Broadhurst, David, Kell, Douglas B., Rowland, Jem J., Goodacre, Royston

Fourier transform infrared (FT-IR) spectroscopy is a rapid, noninvasive technique with considerable potential for application in the food and related industries. We show here that this technique can...

From genomes to systems

Ellis, David I, O'Hagan, Steve, Dunn, Warwick B, Brown, Marie, Vaidyanathan, Seetharaman

A report on the 2nd Conference of the Consortium for Post-Genome Science (CPGS) 'Genomes to Systems', Manchester, UK, 1-3 September 2004.

Functional Genomics Via Metabolic Footprinting: Monitoring Metabolite Secretion by Escherichia Coli Tryptophan Metabolism Mutants Using FT–IR and Direct Injection Electrospray Mass Spectrometry

Kaderbhai, Naheed N., Broadhurst, David I., Ellis, David I., Goodacre, Royston, Kell, Douglas B.

We sought to test the hypothesis that mutant bacterial strains could be discriminated from each other on the basis of the metabolites they secrete into the medium (their ‘metabolic footprint’),...