David J. Anderson

Publication List Details

Period

1969 - 2009

Number

121

Co-Authors

TRPV1-expressing primary afferents generate behavioral responses to pruritogens via multiple mechanisms (2009)

Imamachi, Noritaka, Park, Goon Ho, Lee, Hyosang, Anderson, David J., Simon, Melvin I., Basbaum, Allan I., ...

The mechanisms that generate itch are poorly understood at both the molecular and cellular levels despite its clinical importance. To explore the peripheral neuronal mechanisms underlying itch, we...

Mrgprd Enhances Excitability in Specific Populations of Cutaneous Murine Polymodal Nociceptors (2009)

Rau, Kristofer K., McIlwrath, Sabrina L., Wang, Hong, Lawson, JeffreyJ., Jankowski, Michael P., Zylka, Mark J., ...

The Mas-related G protein-coupled receptor D (Mrgprd) is selectively expressed in nonpeptidergic nociceptors that innervate the outer layers of mammalian skin. The function of Mrgprd in nociceptive...

Distinct subsets of unmyelinated primary sensory fibers mediate behavioral responses to noxious thermal and mechanical stimuli (2009)

Cavanaugh, Daniel J., Lee, Hyosang, Lo, Liching, Shields, Shannon D., Zylka, Mark J., Basbaum, Allan I., ...

Behavioral responses to painful stimuli require peripheral sensory neurons called nociceptors. Electrophysiological studies show that most C-fiber nociceptors are polymodal (i.e., respond to multiple...

Automated monitoring and analysis of social behavior in Drosophila (2009)

Dankert, Heiko, Wang, Liming, Hoopfer, Eric D., Anderson, David J., Perona, Pietro

We introduce a method based on machine vision for automatically measuring aggression and courtship in Drosophila melanogaster. The genetic and neural circuit bases of these innate social behaviors...

An anatomic gene expression atlas of the adult mouse brain (2009)

Ng, Lydia, Bernard, Amy, Lau, Chris, Overly, Caroline C., Dong, Hong-Wei, Kuan, Chihchau, ...

Studying gene expression provides a powerful means of understanding structure-function relationships in the nervous system. The availability of genome-scale in situ hybridization datasets enables new...

An Overview and Status of NASA’s Radioisotope Power Conversion Technology NRA (2008)

David J. Anderson, Wayne A. Wong, Karen L. Tuttle

developing next generation radioisotope power conversion technologies that will enable future missions that have requirements that can not be met by either photovoltaic systems or

Many patients... (2008)

Hubert H. Lim, David J. Anderson

Cortical responses to inferior colliculus stimulation Contact Information

Genetic Structure of Galápagos Populations of the Yellow Warbler (2008)

Robert A. Browne, Elizabeth Collins, David J. Anderson

AbstractSequence variation of control region mitochondrial DNA, phylogenetic reconstruction, and analysis of molecular variance (AMOVA) were used to determine the degree of genetic structure of...

Reproduction And Immune Homeostasis In A Long-Lived Seabird, The Nazca Booby (Sula granti) (2008)

Victor Apanius, Mark A. Westbrock, David J. Anderson

The evolution of longevity requires that the marginal investment in self-maintenance at the expense of reproductive effort is favored by realizing a longer reproductive lifespan. This can occur when...

A common genetic target for environmental and heritable influences on aggressiveness in Drosophila (2008)

Wang, Liming, Dankert, Heiko, Perona, Pietro, Anderson, David J.

Environmental and genetic factors can modulate aggressiveness, but the biological mechanisms underlying their influence are largely unknown. Social experience with conspecifics suppresses...

Boolos, and Logical (2008)

Anderson Stanford David, David J. Anderson, Edward N. Zalta, David J. Anderson, Edward N. Zalta

this paper. The paper was presented in its current form at the Seminar f ur Philosophie, Logik, und Wissenschaftstheorie, Universit at M unchen. We gratefully acknowledge the audience feedback

THE PRESENCE OF THE PACIFIC WHITELEG SHRIMP (LITOPENAEUS VANNAMEI, BOONE, 1931) IN THE WILD IN THAILAND (2007)

WANSUK SENANAN, NONGNUD TANGKROCK-OLAN, SUWANNA PANUTRAKUL, PRAPARSIRI BARNETTE, CHARAN WONGWIWATANAWUTE, NOPPARMARD NIPHONKIT, ...

Pacific whiteleg shrimp (Litopenaeus vannamei, Boone, 1931) was first introduced to Thailand for aquaculture in the late 1990s as an alternative to a native shrimp species, black tiger prawn (Penaeus...

Frege, Boolos, and Logical Objects (2007)

David J. Anderson, Edward N. Zalta

Objects In this section, we discuss the following kinds of logical object: natural cardinals, extensions, directions, shapes, and truth values. The material concerning the latter four kinds of...

Production of insurance eggs in Nazca boobies: costs, benefits, and variable parental quality (2007)

Townsend, Howard M., Anderson, David J.

Numerous studies of birds have demonstrated the value of producing insurance eggs. We have previously found that second eggs provide insurance against failure of first eggs for Nazca boobies (Sula...

Magnetic field perturbation of neural recording and stimulating microelectrodes (2007)

Martinez-Santiesteban, Francisco M, Swanson, Scott D, Noll, Douglas C, Anderson, David J

To improve the overall temporal and spatial resolution of brain mapping techniques, in animal models, some attempts have been reported to join electrophysiological methods with functional magnetic...

Prokineticin 2 Is a Target Gene of Proneural Basic Helix-Loop-Helix Factors for Olfactory Bulb Neurogenesis (2007)

Zhang, Chengkang, Ng, Kwan L., Li, Jia-Da, He, Fei, Anderson, David J., Sun, Yi E., ...

Prokineticin 2, a cysteine-rich secreted protein, regulates diverse biological functions including the neurogenesis of olfactory bulb. Here we show that the PK2 gene is a functional target gene of...

Tracking Signal Subspace Invariance for Blind Separation and Classification of Nonorthogonal Sources in Correlated Noise (2007)

Karim G. Oweiss, David J. Anderson

We investigate a new approach for the problem of source separation in correlated multichannel signal and noise environments. The framework targets the specific case when nonstationary correlated...

Tracking Signal Subspace Invariance for Blind Separation and Classification of Nonorthogonal Sources in Correlated Noise (2007)

Karim G. Oweiss, David J. Anderson

We investigate a new approach for the problem of source separation in correlated multichannel signal and noise environments. The framework targets the specific case when nonstationary correlated...

Spatial mapping of protein abundances in the mouse brain by voxelation integrated with high-throughput liquid chromatography-mass spectrometry (2007)

Petyuk, Vladislav A., Qian, Wei-Jun, Chin, Mark H., Wang, Haixing, Livesay, Eric A., Monroe, Matthew E., ...

Temporally and spatially resolved mapping of protein abundance patterns within the mammalian brain is of significant interest for understanding brain function and molecular etiologies of...

Development of NG2 neural progenitor cells requires Olig gene function (2006)

Ligon, Keith L., Kesari, Santosh, Kitada, Masaaki, Sun, Tao, Arnett, Heather A., Alberta, John A., ...

In the adult central nervous system, two distinct populations of glial cells expressing the chondroitin sulfate proteoglycan NG2 have been described: bipolar progenitor cells and more differentiated...

THE ORIGIN AND DIVERSIFICATION OF GALAPAGOS MOCKINGBIRDS (2006)

Brian S. Arbogast, Sergei V. Drovetski, Robert L. Curry, Peter T. Boag, Gilles Seutin, Peter R. Grant, ...

Evolutionary radiations of colonists on archipelagos provide valuable insight into mechanisms and modes of speciation. The apparent diversification of Galapagos mockingbirds (Nesomimus) provoked...

Olig2+ neuroepithelial motoneuron progenitors are not multipotent stem cells in vivo (2006)

Mukouyama, Yoh-suke, Deneen, Benjamin, Lukaszewwicz, Agnès, Novitch, Bennett G., Wichterle, Hynek, Jessell, Thomas M., ...

Neurons and glia are thought to arise from multipotent and self-renewing stem cells, which comprise the majority of neuroepithelial cells in the ventricular zone (VZ) of the early embryonic CNS....

Late-emigrating neural crest cells in the roof plate are restricted to a sensory fate by GDF7 (2005)

Lo, Liching, Dormand, Emma L., Anderson, David J.

Lineage-tracing experiments have shown that some premigratory neural crest cells generate both sensory (S) and autonomic (A) derivatives, whereas others generate only S derivatives. Whether this...

Peripheral nerve-derived VEGF promotes arterial differentiation via neuropilin 1-mediated positive feedback (2005)

Mukouyama, Yoh-suke, Gerber, Hans-Peter, Ferrara, Napoleone, Gu, Chenghua, Anderson, David J.

In developing limb skin, peripheral nerves are required for arterial differentiation, and guide the pattern of arterial branching. In vitro experiments suggest that nerve-derived VEGF may be...

Neural crest stem cells undergo multilineage differentiation in developing peripheral nerves to generate endoneurial fibroblasts in addition to Schwann cells (2004)

Joseph, Nancy M., Mukouyama, Yoh-suke, Mosher, Jack T., Jaegle, Martine, Crone, Steven A., Dormand, Emma-Louise, ...

Neural crest stem cells (NCSCs) persist in peripheral nerves throughout late gestation but their function is unknown. Current models of nerve development only consider the generation of Schwann cells...

LQG Control of a Deformable Mirror Adaptive Optics System with Time- Delayed Measurements (2004)

Anderson, David J.

This thesis proposes a linear quadratic Gaussian (LQG) control law for a ground-based deformable mirror adaptive optics system. The incoming image wavefront is distorted, primarily in phase, due to...

Trace but not delay fear conditioning requires attention and the anterior cingulate cortex (2003)

Han, C. J., O'Tuathaigh, Colm M., Van Trigt, Laurent, Quinn, Jennifer J., Fanselow, Michael S., Mongeau, Raymond, ...

Higher cognitive functions such as attention have been difficult to model in genetically tractable organisms. In humans, attention-distracting stimuli interfere with trace but not delay conditioning,...

Atypical expansion in mice of the sensory neuron-specific Mrg G protein-coupled receptor family (2003)

Zylka, Mark J., Dong, Xinzhong, Southwell, Amber L., Anderson, David J.

The Mas-related genes (Mrgs) comprise a family of >50 G protein-coupled receptors (GPCRs), many of which are expressed in specific subsets of nociceptive sensory neurons in mice. In contrast, humans...

Orphan G protein-coupled receptors MrgA1 and MrgC11 are distinctively activated by RF-amide-related peptides through the G{alpha}q/11 pathway (2002)

Han, Sang-Kyou, Dong, Xinzhong, Hwang, Jong-Ik, Zylka, Mark J., Anderson, David J., Simon, Melvin I.

MrgA1 and MrgC11 belong to a recently identified family of orphan G-protein coupled receptors, called mrgs (mas-related genes). They are only expressed in a specific subset of sensory neurons that...

Transient expression of the bHLH factor neurogenin-2 marks a subpopulation of neural crest cells biased for a sensory but not a neuronal fate (2002)

Zirlinger, Mariela, Lo, Liching, McMahon, Jill, McMahon, Andrew P., Anderson, David J.

Lineage-tracing experiments have indicated that some premigratory neural crest cells (NCCs) are pleuripotent, generating sensory and sympathetic neurons and their associated glia. Using an inducible...

Comparison of the generic neuronal differentiation and neuron subtype specification functions of mammalian achaete-scute and atonal homologs in cultured neural progenitor cells (2002)

Lo, Liching, Dormand, Emma, Greenwood, Amy, Anderson, David J.

In the vertebrate peripheral nervous system, the proneural genes neurogenin 1 and neurogenin 2 (Ngn1 and Ngn2), and Mash1 are required for sensory and autonomic neurogenesis, respectively. In...

Arteriolar and venular patterning in retinas of mice selectively expressing VEGF isoforms (2002)

Stalmans, Ingeborg, Ng, Yin-Shan, Rohan, Richard, Fruttiger, Marcus, Bouché, Ann, Ÿuce, Ali, ...

The murine VEGF gene is alternatively transcribed to yield the VEGF120, VEGF164, and VEGF188 isoforms, which differ in their potential to bind to heparan sulfate and neuropilin-1 and to stimulate...

Arteriolar and venular patterning in retinas of mice selectively expressing VEGF isoforms (2002)

Stalmans, Ingeborg; U0013670, Ng, Yin-Shan, Rohan, Richard, Fruttiger, Marcus, Bouché, Ann, Yuce, Ali, ...

The murine VEGF gene is alternatively transcribed to yield the VEGF(120), VEGF(164), and VEGF(188) isoforms, which differ in their potential to bind to heparan sulfate and neuropilin-1 and to...

Surface modification of neural recording electrodes with conducting polymer/biomolecule blends (2001)

Cui, Xinyan, Lee, Valerie A., Raphael, Yehoash, Wiler, James A., Hetke, Jamille F., Anderson, David J., ...

The interface between micromachined neural microelectrodes and neural tissue plays an important role in chronic in vivo recording. Electrochemical polymerization was used to optimize the surface of...

Amygdala-enriched genes identified by microarray technology are restricted to specific amygdaloid subnuclei (2001)

Zirlinger, Mariela, Kreiman, Gabriel, Anderson, David J.

Microarray technology represents a potentially powerful method for identifying cell type- and regionally restricted genes expressed in the brain. Here we have combined a microarray analysis of...

What do pain scores mean to patients (2001)

Anderson, David J.

Typescript (photocopy) Includes bibliographical references (leaves 48-51)

Constitutive expression of the neuron-restrictive silencer factor (NRSF)/REST in differentiating neurons disrupts neuronal gene expression and causes axon pathfinding errors in vivo (2000)

Paquette, Alice J., Perez, Sharon E., Anderson, David J.

The neuron-restrictive silencer factor (NRSF; also known as REST for repressor element-1 silencing transcription factor) is a transcriptional repressor of multiple neuronal genes, but little is known...

NOCTURNAL AND DIURNAL FORAGING ACTIVITY OF HAWAIIAN ALBATROSSES DETECTED WITH A NEW IMMERSION MONITOR (2000)

Patricia Fernández, David J. Anderson

We used a new immersion monitor to study the foraging movements of two species of albatrosses that nest in the Hawaiian Islands. The monitors showed that breeding male Black-footed Albatrosses...

Protein Kinase A Regulates Cholinergic Gene Expression in PC12 Cells: REST4 Silences the Silencing Activity of Neuron-Restrictive Silencer Factor/REST (1999)

Shimojo, Masahito, Paquette, Alice J., Anderson, David J., Hersh, Louis B.

The role of protein kinase A in regulating transcription of the cholinergic gene locus, which contains both the vesicular acetylcholine transporter gene and the choline acetyltransferase gene, was...

Identification of dividing, determined sensory neuron precursors in the mammalian neural crest (1999)

Greenwood, Amy L., Turner, Eric E., Anderson, David J.

Sensory and autonomic neurons of the vertebrate peripheral nervous system are derived from the neural crest. Here we use the expression of lineage-specific transcription factors as a means to...

Early specification of sensory neuron fate revealed by expression and function of neurogenins in the chick embryo (1999)

Perez, Sharon E., Rebelo, Sandra, Anderson, David J.

The generation of sensory and autonomic neurons from the neural crest requires the functions of two classes of basic helix-loop-helix (bHLH) transcription factors, the Neurogenins (NGNs) and MASH-1,...

Isolation and characterization of mammalian homologs of the Drosophila gene glial cells missing (1998)

Kim, Jaesang, Jones, Bradley W., Zock, Christiane, Chen, Zhoufeng, Wang, Hai, Goodman, Corey S., ...

The glial cells missing (gcm) gene in Drosophila encodes a transcription factor that determines the choice between glial and neuronal fates. We report here the isolation of two mammalian gcm...

MASH1 activates expression of the paired homeodomain transcription factor Phox2a, and couples pan-neuronal and subtype-specific components of autonomic neuronal identity (1998)

Lo, Liching, Tiveron, Marie-Catherine, Anderson, David J.

We have investigated the genetic circuitry underlying the determination of neuronal identity, using mammalian peripheral autonomic neurons as a model system. Previously, we showed that treatment of...

Integration of multiple instructive cues by neural crest stem cells reveals cell-intrinsic biases in relative growth factor responsiveness (1997)

Shah, Nirao M., Anderson, David J.

Growth factors can influence lineage determination of neural crest stem cells (NCSCs) in an instructive manner, in vitro. Because NCSCs are likely exposed to multiple signals in vivo, these findings...

Cell type-specific regulation of choline acetyltransferase gene expression - Role of the neuron-restrictive silencer element and cholinergic-specific enhancer (1996)

Lonnerberg, Peter, Schoenherr, Christopher J., Anderson, David J., Ibáñez, Carlos F.

This study demonstrates the presence of positive and negative regulatory elements within a 2336-base pair-long region of the rat choline acetyltransferase (ChAT) gene promoter that cooperate to...

Identification of potential target genes for the neuron-restrictive silencer factor (1996)

Schoenherr, Christopher J., Paquette, Alice J., Anderson, David J.

The neuron-restrictive silencer factor (NRSF) represses transcription of several neuronal genes in nonneuronal cells by binding to a 21-bp element called the neuron-restrictive silencer element...

Differential regulation of transcription factor gene expression and phenotypic markers in developing sympathetic neurons (1995)

Groves, Andrew K., George, Kathleen M., Tissier-Seta, Jean-Phillipe, Engel, James Douglas, Brunet, Jean-François, Anderson, David J.

We have examined the regulation of transcription factor gene expression and phenotypic markers in developing chick sympathetic neurons. Sympathetic progenitor cells first express the bHLH...

Expression of trk in MAH Cells Lacking the p75 Low-Affinty Nerve Growth Factor Receptor is Sufficient to Permit Nerve Growth Factor-Induced Differentiation to Postmitotic Neurons (1994)

Verdi, Joseph M., Ip, Nancy, Yancopolous, George D., Anderson, David J.

We have transfected MAH cells, an immortalized sympathoadrenal progenitor cell line, with a plasmid encoding the 140-kDa Trk protein, a nerve growth factor (NGF) receptor with protein-tyrosine kinase...

XASH-3, a novel Xenopus achaete-scute homolog, provides an early marker of planar neural induction and position along the mediolateral axis of the neural plate (1993)

Zimmerman, Kathryn, Shih, John, Bars, Julie, Collazo, Andres, Anderson, David J.

We have isolated a novel Xenopus homolog of the Drosophila achaete-scute genes, called XASH-3. XASH-3 expression is neural specific and is detected as early as stage 11 1/2, making it one of the...

DNA Binding and Transcriptional Regulatory Activity of Mammalian Achaete-Acute Homologous (MASH) Proteins Revealed by Interaction with a Muscle-Specific Enhancer (1992)

Johnson, Jane E., Birren, Susan J., Saito, Tetsuichiro, Anderson, David J.

The MASH genes are vertebrate homologues of achaete-scute, genes required for neuronal determination in Drosophila. The sequence of MASH1 and MASH2 contains a basic helix-loop-helix (bHLH) motif that...

Shared-stimulus driving and connectivity in groups of neurons in the dorsal cochlear nucleus (1991)

Kipke, Daryl R., Clopton, Ben M., Anderson, David J.

Extracellular spike discharges were recorded from ensembles of up to five neurons simultaneously in the DCN of guinea pig using solid-state, thin-film, multichannel electrodes having up to five...

A parallel algorithm for determining two-dimensional object positions using incomplete information about their boundaries (1989)

Amini, Amir A., Weymouth, Terry E., Anderson, David J.

Extraction of two-dimensional object locations using current techniques is a computationally intensive process. In this paper a parallel algorithm is presented that can specify the location of...

Parametric analysis of dynamic postural responses (1984)

Anderson, David J., Werness, Susan A. S.

A detailed theoretical understanding of postural control mechanisms must be preceded by careful quantification of both the deterministic and stochastic aspects of postural behavior of normal and...

A computer program for linear nonparametric and parametric identification of biological data (1984)

Werness, Susan A. S., Anderson, David J.

A computer program package for parametric and nonparametric linear system identification of both static and dynamic biological data, written for an LSI-11 minicomputer with 28 K of memory, is...

Signal recognition protein is required for the integration of acetylcholine receptor delta subunit, a transmembrane glycoprotein, into the endoplasmic reticulum membrane (1982)

Anderson, David J., Walter, Peter, Blobel, Günter

Purified Signal Recognition Protein (SRP) has previously been shown to be required for the translocation of secretory proteins across the microsomal membrane (Walter and Blobel, 1980. Proc. Natl....

In vitro synthesis, glycosylation, and membrane insertion of the four subunits of Torpedo acetylcholine receptor (1981)

Anderson, David J., Blobel, Gunter

We have characterized the early biosynthetic forms of the Torpedo electroplax acetylcholine receptor by using a cell-free protein synthesizing system. We obtained primary translation products of...

Commensalism in an ant-aphid association. (1980)

Anderson, David J.

http://deepblue.lib.umich.edu/bitstream/2027.42/53272/1/1706.pdf

Electrocochleography and experimentally induced loudness recruitment (1979)

Pugh, James E., Moody, David B., Anderson, David J.

The relationship between changes in loudness and the cochlear whole-nerve potential following experimentally produced deafness was studied in an animal model. Reaction time of a subject's response to...

Single unit responses recorded from the first order neuron of the pigeon auditory system (1976)

Gross, Nathan B., Anderson, David J.

Intracochlear recordings from the first order neurons in the eighth nerve of the pigeon were made with microelectrodes. The basic response characteristics of the single units were similar to those...

The tonotopic organization of the auditory thalamus of the squirrel monkey (Saimiri sciureus) (1974)

Gross, Nathan B., Lifschitz, Wladimiro S., Anderson, David J.

Single unit responses were recorded from the auditory thalamus of anesthetized squirrel monkeys. The microelectrode penetrations had an orientation perpendicular to the sagittal plane. The small cell...

A chronic implant for recording of cochlear potentials in primates This work was supported in part by NIH Program Project grant NS 05785-08 and NINDS Special Fellowship 5F11 NS2425-02. (1973)

Pugh, James E., Horwitz, Milton R., Anderson, David J., Singleton, Earl F.

A new technique for the continuous recording of peripheral bioelectrical activity in the auditory system of primates is described. Because of basic differences in the anatomy of the temporal bone,...

Constitutive expression of the neuron-restrictive silencer factor (NRSF)/REST in differentiating neurons disrupts neuronal gene expression and causes axon pathfinding errors in vivo

Paquette, Alice J., Perez, Sharon E., Anderson, David J.

The neuron-restrictive silencer factor (NRSF; also known as REST for repressor element-1 silencing transcription factor) is a transcriptional repressor of multiple neuronal genes, but little is known...

Isolation and characterization of mammalian homologs of the Drosophila gene glial cells missing

Kim, Jaesang, Jones, Bradley W., Zock, Christiane, Chen, Zhoufeng, Wang, Hai, Goodman, Corey S., ...

The glial cells missing (gcm) gene in Drosophila encodes a transcription factor that determines the choice between glial and neuronal fates. We report here the isolation of two mammalian gcm...

Integration of multiple instructive cues by neural crest stem cells reveals cell-intrinsic biases in relative growth factor responsiveness

Shah, Nirao M., Anderson, David J.

Growth factors can influence lineage determination of neural crest stem cells (NCSCs) in an instructive manner, in vitro. Because NCSCs are likely exposed to multiple signals in vivo, these findings...

Amygdala-enriched genes identified by microarray technology are restricted to specific amygdaloid subnuclei

Zirlinger, Mariela, Kreiman, Gabriel, Anderson, David J.

Microarray technology represents a potentially powerful method for identifying cell type- and regionally restricted genes expressed in the brain. Here we have combined a microarray analysis of...

Protein Kinase A Regulates Cholinergic Gene Expression in PC12 Cells: REST4 Silences the Silencing Activity of Neuron-Restrictive Silencer Factor/REST

Shimojo, Masahito, Paquette, Alice J., Anderson, David J., Hersh, Louis B.

The role of protein kinase A in regulating transcription of the cholinergic gene locus, which contains both the vesicular acetylcholine transporter gene and the choline acetyltransferase gene, was...

Transient expression of the bHLH factor neurogenin-2 marks a subpopulation of neural crest cells biased for a sensory but not a neuronal fate

Zirlinger, Mariela, Lo, Liching, McMahon, Jill, McMahon, Andrew P., Anderson, David J.

Lineage-tracing experiments have indicated that some premigratory neural crest cells (NCCs) are pleuripotent, generating sensory and sympathetic neurons and their associated glia. Using an inducible...

Global analysis of the Deinococcus radiodurans proteome by using accurate mass tags

Lipton, Mary S., Paša-Tolić, Ljiljana, Anderson, Gordon A., Anderson, David J., Auberry, Deanna L., Battista, John R., ...

Understanding biological systems and the roles of their constituents is facilitated by the ability to make quantitative, sensitive, and comprehensive measurements of how their proteome changes, e.g.,...

Orphan G protein-coupled receptors MrgA1 and MrgC11 are distinctively activated by RF-amide-related peptides through the Gαq/11 pathway

Han, Sang-Kyou, Dong, Xinzhong, Hwang, Jong-Ik, Zylka, Mark J., Anderson, David J., Simon, Melvin I.

MrgA1 and MrgC11 belong to a recently identified family of orphan G-protein coupled receptors, called mrgs (mas-related genes). They are only expressed in a specific subset of sensory neurons that...

Arteriolar and venular patterning in retinas of mice selectively expressing VEGF isoforms

Stalmans, Ingeborg, Ng, Yin-Shan, Rohan, Richard, Fruttiger, Marcus, Bouché, Ann, Ÿuce, Ali, ...

The murine VEGF gene is alternatively transcribed to yield the VEGF120, VEGF164, and VEGF188 isoforms, which differ in their potential to bind to heparan sulfate and neuropilin-1 and to stimulate...

Die-Away Kinetic Analysis of the Capacity of Epilithic and Planktonic Bacteria from Clean and Polluted River Water To Biodegrade Sodium Dodecyl Sulfate

Anderson, David J., Day, Martin J., Russell, Nicholas J., White, Graham F.

The capacities of epilithic and planktonic river bacterial populations to degrade sodium dodecyl sulfate (SDS) in samples taken at two times during 1987 from one clean and four polluted sites in a...

Atypical expansion in mice of the sensory neuron-specific Mrg G protein-coupled receptor family

Zylka, Mark J., Dong, Xinzhong, Southwell, Amber L., Anderson, David J.

The Mas-related genes (Mrgs) comprise a family of >50 G protein-coupled receptors (GPCRs), many of which are expressed in specific subsets of nociceptive sensory neurons in mice. In contrast, humans...

Trace but not delay fear conditioning requires attention and the anterior cingulate cortex

Han, C. J., O'Tuathaigh, Colm M., Van Trigt, Laurent, Quinn, Jennifer J., Fanselow, Michael S., Mongeau, Raymond, ...

Higher cognitive functions such as attention have been difficult to model in genetically tractable organisms. In humans, attention-distracting stimuli interfere with trace but not delay conditioning,...

A role for neural determination genes in specifying the dorsoventral identity of telencephalic neurons

Fode, Carol, Ma, Qiufu, Casarosa, Simona, Ang, Siew-Lan, Anderson, David J., Guillemot, François

Neurogenin1 (Ngn1), Neurogenin2 (Ngn2), and Mash1 encode bHLH transcription factors with neuronal determination functions. In the telencephalon, the Ngns and Mash1 are expressed at high levels in...

NEUROGENIN1 and NEUROGENIN2 control two distinct waves of neurogenesis in developing dorsal root ganglia

Ma, Qiufu, Fode, Carol, Guillemot, Francois, Anderson, David J.

Different classes of sensory neurons in dorsal root ganglia (DRG) are generated in two waves: large-diameter trkC+ and trkB+ neurons are born first, followed by small-diameter trkA+ neurons. All such...

Late-emigrating neural crest cells in the roof plate are restricted to a sensory fate by GDF7

Lo, Liching, Dormand, Emma L., Anderson, David J.

Lineage-tracing experiments have shown that some premigratory neural crest cells generate both sensory (S) and autonomic (A) derivatives, whereas others generate only S derivatives. Whether this...

Divergent functions of the proneural genes Mash1 and Ngn2 in the specification of neuronal subtype identity

Parras, Carlos M., Schuurmans, Carol, Scardigli, Raffaella, Kim, Jaesang, Anderson, David J., Guillemot, François

The neural bHLH genes Mash1 and Ngn2 are expressed in complementary populations of neural progenitors in the central and peripheral nervous systems. Here, we have systematically compared the...

Olig2+ neuroepithelial motoneuron progenitors are not multipotent stem cells in vivo

Mukouyama, Yoh-suke, Deneen, Benjamin, Lukaszewicz, Agnès, Novitch, Bennett G., Wichterle, Hynek, Jessell, Thomas M., ...

Neurons and glia are thought to arise from multipotent and self-renewing stem cells, which comprise the majority of neuroepithelial cells in the ventricular zone (VZ) of the early embryonic CNS....

Development of NG2 neural progenitor cells requires Olig gene function

Ligon, Keith L., Kesari, Santosh, Kitada, Masaaki, Sun, Tao, Arnett, Heather A., Alberta, John A., ...

In the adult central nervous system, two distinct populations of glial cells expressing the chondroitin sulfate proteoglycan NG2 have been described: bipolar progenitor cells and more differentiated...

Constitutive expression of the neuron-restrictive silencer factor (NRSF)/REST in differentiating neurons disrupts neuronal gene expression and causes axon pathfinding errors in vivo

Paquette, Alice J., Perez, Sharon E., Anderson, David J.

The neuron-restrictive silencer factor (NRSF; also known as REST for repressor element-1 silencing transcription factor) is a transcriptional repressor of multiple neuronal genes, but little is known...

Isolation and characterization of mammalian homologs of the Drosophila gene glial cells missing

Kim, Jaesang, Jones, Bradley W., Zock, Christiane, Chen, Zhoufeng, Wang, Hai, Goodman, Corey S., ...

The glial cells missing (gcm) gene in Drosophila encodes a transcription factor that determines the choice between glial and neuronal fates. We report here the isolation of two mammalian gcm...

Integration of multiple instructive cues by neural crest stem cells reveals cell-intrinsic biases in relative growth factor responsiveness

Shah, Nirao M., Anderson, David J.

Growth factors can influence lineage determination of neural crest stem cells (NCSCs) in an instructive manner, in vitro. Because NCSCs are likely exposed to multiple signals in vivo, these findings...

Amygdala-enriched genes identified by microarray technology are restricted to specific amygdaloid subnuclei

Zirlinger, Mariela, Kreiman, Gabriel, Anderson, David J.

Microarray technology represents a potentially powerful method for identifying cell type- and regionally restricted genes expressed in the brain. Here we have combined a microarray analysis of...

Protein Kinase A Regulates Cholinergic Gene Expression in PC12 Cells: REST4 Silences the Silencing Activity of Neuron-Restrictive Silencer Factor/REST

Shimojo, Masahito, Paquette, Alice J., Anderson, David J., Hersh, Louis B.

The role of protein kinase A in regulating transcription of the cholinergic gene locus, which contains both the vesicular acetylcholine transporter gene and the choline acetyltransferase gene, was...

Transient expression of the bHLH factor neurogenin-2 marks a subpopulation of neural crest cells biased for a sensory but not a neuronal fate

Zirlinger, Mariela, Lo, Liching, McMahon, Jill, McMahon, Andrew P., Anderson, David J.

Lineage-tracing experiments have indicated that some premigratory neural crest cells (NCCs) are pleuripotent, generating sensory and sympathetic neurons and their associated glia. Using an inducible...

Global analysis of the Deinococcus radiodurans proteome by using accurate mass tags

Lipton, Mary S., Paša-Tolić, Ljiljana, Anderson, Gordon A., Anderson, David J., Auberry, Deanna L., Battista, John R., ...

Understanding biological systems and the roles of their constituents is facilitated by the ability to make quantitative, sensitive, and comprehensive measurements of how their proteome changes, e.g.,...

Orphan G protein-coupled receptors MrgA1 and MrgC11 are distinctively activated by RF-amide-related peptides through the Gαq/11 pathway

Han, Sang-Kyou, Dong, Xinzhong, Hwang, Jong-Ik, Zylka, Mark J., Anderson, David J., Simon, Melvin I.

MrgA1 and MrgC11 belong to a recently identified family of orphan G-protein coupled receptors, called mrgs (mas-related genes). They are only expressed in a specific subset of sensory neurons that...

Arteriolar and venular patterning in retinas of mice selectively expressing VEGF isoforms

Stalmans, Ingeborg, Ng, Yin-Shan, Rohan, Richard, Fruttiger, Marcus, Bouché, Ann, Ÿuce, Ali, ...

The murine VEGF gene is alternatively transcribed to yield the VEGF120, VEGF164, and VEGF188 isoforms, which differ in their potential to bind to heparan sulfate and neuropilin-1 and to stimulate...

Divergent functions of the proneural genes Mash1 and Ngn2 in the specification of neuronal subtype identity

Parras, Carlos M., Schuurmans, Carol, Scardigli, Raffaella, Kim, Jaesang, Anderson, David J., Guillemot, François

The neural bHLH genes Mash1 and Ngn2 are expressed in complementary populations of neural progenitors in the central and peripheral nervous systems. Here, we have systematically compared the...

Die-Away Kinetic Analysis of the Capacity of Epilithic and Planktonic Bacteria from Clean and Polluted River Water To Biodegrade Sodium Dodecyl Sulfate

Anderson, David J., Day, Martin J., Russell, Nicholas J., White, Graham F.

The capacities of epilithic and planktonic river bacterial populations to degrade sodium dodecyl sulfate (SDS) in samples taken at two times during 1987 from one clean and four polluted sites in a...

Atypical expansion in mice of the sensory neuron-specific Mrg G protein-coupled receptor family

Zylka, Mark J., Dong, Xinzhong, Southwell, Amber L., Anderson, David J.

The Mas-related genes (Mrgs) comprise a family of >50 G protein-coupled receptors (GPCRs), many of which are expressed in specific subsets of nociceptive sensory neurons in mice. In contrast, humans...

Trace but not delay fear conditioning requires attention and the anterior cingulate cortex

Han, C. J., O'Tuathaigh, Colm M., Van Trigt, Laurent, Quinn, Jennifer J., Fanselow, Michael S., Mongeau, Raymond, ...

Higher cognitive functions such as attention have been difficult to model in genetically tractable organisms. In humans, attention-distracting stimuli interfere with trace but not delay conditioning,...

A role for neural determination genes in specifying the dorsoventral identity of telencephalic neurons

Fode, Carol, Ma, Qiufu, Casarosa, Simona, Ang, Siew-Lan, Anderson, David J., Guillemot, François

Neurogenin1 (Ngn1), Neurogenin2 (Ngn2), and Mash1 encode bHLH transcription factors with neuronal determination functions. In the telencephalon, the Ngns and Mash1 are expressed at high levels in...

NEUROGENIN1 and NEUROGENIN2 control two distinct waves of neurogenesis in developing dorsal root ganglia

Ma, Qiufu, Fode, Carol, Guillemot, Francois, Anderson, David J.

Different classes of sensory neurons in dorsal root ganglia (DRG) are generated in two waves: large-diameter trkC+ and trkB+ neurons are born first, followed by small-diameter trkA+ neurons. All such...

Late-emigrating neural crest cells in the roof plate are restricted to a sensory fate by GDF7

Lo, Liching, Dormand, Emma L., Anderson, David J.

Lineage-tracing experiments have shown that some premigratory neural crest cells generate both sensory (S) and autonomic (A) derivatives, whereas others generate only S derivatives. Whether this...

Olig2+ neuroepithelial motoneuron progenitors are not multipotent stem cells in vivo

Mukouyama, Yoh-suke, Deneen, Benjamin, Lukaszewicz, Agnès, Novitch, Bennett G., Wichterle, Hynek, Jessell, Thomas M., ...

Neurons and glia are thought to arise from multipotent and self-renewing stem cells, which comprise the majority of neuroepithelial cells in the ventricular zone (VZ) of the early embryonic CNS....

Development of NG2 neural progenitor cells requires Olig gene function

Ligon, Keith L., Kesari, Santosh, Kitada, Masaaki, Sun, Tao, Arnett, Heather A., Alberta, John A., ...

In the adult central nervous system, two distinct populations of glial cells expressing the chondroitin sulfate proteoglycan NG2 have been described: bipolar progenitor cells and more differentiated...

Spatial mapping of protein abundances in the mouse brain by voxelation integrated with high-throughput liquid chromatography–mass spectrometry

Petyuk, Vladislav A., Qian, Wei-Jun, Chin, Mark H., Wang, Haixing, Livesay, Eric A., Monroe, Matthew E., ...

Temporally and spatially resolved mapping of protein abundance patterns within the mammalian brain is of significant interest for understanding brain function and molecular etiologies of...

Serial monogamy and sex ratio bias in Nazca boobies

Maness, Terri J, Anderson, David J

Biased operational sex ratios (OSRs) can drive sexual selection on members of the over-represented sex via competition for mates, causing higher variance and skew in reproductive success (RS) among...

Spatial mapping of the neurite and soma proteomes reveals a functional Cdc42/Rac regulatory network

Pertz, Olivier C., Wang, Yingchun, Yang, Feng, Wang, Wei, Gay, Laurie J., Gristenko, Marina A., ...

Neurite extension and growth cone navigation are guided by extracellular cues that control cytoskeletal rearrangements. However, understanding the complex signaling mechanisms that mediate...

A common genetic target for environmental and heritable influences on aggressiveness in Drosophila

Wang, Liming, Dankert, Heiko, Perona, Pietro, Anderson, David J.

Environmental and genetic factors can modulate aggressiveness, but the biological mechanisms underlying their influence are largely unknown. Social experience with conspecifics suppresses...

Electrophysiological Validation of a Human Prototype Auditory Midbrain Implant in a Guinea Pig Model

Lenarz, Minoo, Lim, Hubert H., Patrick, James F., Anderson, David J., Lenarz, Thomas

The auditory midbrain implant (AMI) is a new treatment for hearing restoration in patients with neural deafness or surgically inaccessible cochleae who cannot benefit from cochlear implants (CI)....

Wind, Waves, and Wing Loading: Morphological Specialization May Limit Range Expansion of Endangered Albatrosses

Suryan, Robert M., Anderson, David J., Shaffer, Scott A., Roby, Daniel D., Tremblay, Yann, Costa, Daniel P., ...

Among the varied adaptations for avian flight, the morphological traits allowing large-bodied albatrosses to capitalize on wind and wave energy for efficient long-distance flight are unparalleled....

Distinct subsets of unmyelinated primary sensory fibers mediate behavioral responses to noxious thermal and mechanical stimuli

Cavanaugh, Daniel J., Lee, Hyosang, Lo, Liching, Shields, Shannon D., Zylka, Mark J., Basbaum, Allan I., ...

Behavioral responses to painful stimuli require peripheral sensory neurons called nociceptors. Electrophysiological studies show that most C-fiber nociceptors are polymodal (i.e., respond to multiple...