David J. Pagliarini

Discovery of PTPMT1, a novel mitochondrial phosphatase involved in ATP production and insulin secretion in pancreatic beta cells / (2005)

Pagliarini, David J. (David James).

Thesis (Ph. D.)--University of California, San Diego, 2005.

Dual Specificity Phosphatases 18 and 21 Target to Opposing Sides of the Mitochondrial Inner Membrane*S⃞

Rardin, Matthew J., Wiley, Sandra E., Murphy, Anne N., Pagliarini, David J., Dixon, Jack E.

Although large-scale approaches have identified numerous mitochondrial phosphoproteins, little is known about the mitochondrial kinases and phosphatases that regulate these phosphoproteins. Here, we...

Mutation of C20orf7 Disrupts Complex I Assembly and Causes Lethal Neonatal Mitochondrial Disease

Sugiana, Canny, Pagliarini, David J., McKenzie, Matthew, Kirby, Denise M., Salemi, Renato, Abu-Amero, Khaled K., ...

Complex I (NADH:ubiquinone oxidoreductase) is the first and largest multimeric complex of the mitochondrial respiratory chain. Human complex I comprises seven subunits encoded by mitochondrial DNA...

Upstream open reading frames cause widespread reduction of protein expression and are polymorphic among humans

Calvo, Sarah E., Pagliarini, David J., Mootha, Vamsi K.

Upstream ORFs (uORFs) are mRNA elements defined by a start codon in the 5′ UTR that is out-of-frame with the main coding sequence. Although uORFs are present in approximately half of human and...