David L. McCormick

Subchronic Toxicity and Toxicogenomic Evaluation of Tamoxifen Citrate + Bexarotene in Female Rats (2007)

Horn, Thomas L., Torres, Karen E. O., Naylor, Jennifer M., Cwik, Michael J., Detrisac, Carol J., Kapetanovic, Izet M., ...

Tamoxifen (TAM) is a nonsteroidal antiestrogen that prevents estrogen receptor–positive breast cancer in rodents and humans. Bexarotene (BEX), a selective agonist for retinoid X receptors, inhibits...

Chemoprevention of rat prostate carcinogenesis by dietary 16{alpha}-fluoro-5-androsten-17-one (fluasterone), a minimally androgenic analog of dehydroepiandrosterone (2007)

McCormick, David L., Johnson, William D., Kozub, Nicole M., Rao, K.V.N., Lubet, Ronald A., Steele, Vernon E., ...

Dehydroepiandrosterone (DHEA) is a potent inhibitor of prostate carcinogenesis in rats. However, concerns related to the possible androgenicity of DHEA may preclude its use for chemoprevention of...

Chemoprevention of rat prostate carcinogenesis by dietary 16{alpha}-fluoro-5-androsten-17-one (fluasterone), a minimally androgenic analog of dehydroepiandrosterone (2006)

McCormick, David L., Johnson, William D., Kozub, Nicole M., Rao, K. V. N., Lubet, Ronald A., Steele, Vernon E., ...

Dehydroepiandrosterone (DHEA) is a potent inhibitor of prostate carcinogenesis in rats. However, concerns related to the possible androgenicity of DHEA may preclude its use for chemoprevention of...

Magnetic Fields and Mammary Cancer in Rodents: A Critical Review and Evaluation of Published Literature (2000)

Gary A. Boorman, David L. McCormick, Jerrold M. Ward, Joseph K. Haseman, Robert C. Sills

Boorman, G.A., McCormick, D.L., Ward, J.M., Haseman, J.K. and Sills, R.C. Magnetic Fields and Mammary Cancer in Rodents: A Critical Review and Evaluation of Published Literature. Epidemiological data...

Evaluation of the Developmental Toxicity of 60 Hz Magnetic Fields and Harmonic Frequencies in Sprague-Dawley Rats (2000)

Bernadette M. Ryan, Mary Polen, James R. Gauger, Eddie Mallett, Jr., Mark B. Kearns, Tanya L. Bryan, ...

Ryan, B. M., Polen, M., Gauger, J. R., Mallett, B., Jr., Kearns, M. E., Bryan, T. E. and McCormick, D. L. Evaluation of the Developmental Toxicity of 60 Hz Magnetic Fields and Harmonic Frequencies in...

60 Hz Magnetic Fields Do Not Enhance Cell Killing by Genotoxic Chemicals in Ataxia Telangiectasia and Normal Lymphoblastoid Cells (2000)

Lise I. Loberg, Melissa J. Luther, James R. Gauger, David L. McCormick

Loberg, L. I., Luther, M. J., Gauger, J. R. and McCormick, D. L. 60 Hz Magnetic Fields Do Not Enhance Cell Killing by Genotoxic Chemicals in Ataxia Telangiectasia and Normal Lymphoblastoid Cells....

Modulation of Natural Killer Cell Function after Exposure to 60 Hz Magnetic Fields: Confirmation of the Effect in Mature B6C3F1 Mice (2000)

Robert V. House, David L. McCormick

House, R. V. and McCormick, D. L. Modulation of Natural Killer Cell Function after Exposure to 60 Hz Magnetic Fields: Confirmation of the Effect in Mature B6C3F1 Mice. In a previous study, we...

Cell Viability and Growth in a Battery of Human Breast Cancer Cell Lines Exposed to 60 Hz Magnetic Fields (2000)

Lise I. Loberg, William R. Engdahl, James R. Gauger, David L. McCormick

Loberg, L. I., Engdahl, W. R., Gauger, J. R. and McCormick, D. L. Cell Viability and Growth in a Battery of Human Breast Cancer Cell Lines Exposed to 60 Hz Magnetic Fields. Epidemiological data...

Gene expression in human breast epithelial cells exposed to 60 Hz magnetic fields (1999)

Loberg, Lise I., Gauger, James R., Buthod, James L., Engdahl, William R., McCormick, David L.

Epidemiology suggests a possible relationship between exposure to power frequency magnetic fields (EMF) and breast cancer. One mechanism through which EMF could stimulate breast cancer induction is...

Immune Function and Host Defense in Rodents Exposed to 60-Hz Magnetic Fields (1996)

HOUSE, ROBERT V., RATAJCZAK, HELEN V., GAUGER, JAMES R., JOHNSON, TIM R., THOMAS, PETER T., MCCORMICK, DAVID L.

This study was conducted to evaluate the influence of sub-chronic exposure to pure, linearly polarized 60-Hz magnetic fields (MF) on the host immune response in mice. The experimental design was as...

MOLECULAR EPIDEMIOLOGY AND CANCER PREVENTION: Differential activity of aspirin, ketoprofen and sulindac as cancer chemopreventive agents in the mouse urinary bladder (1996)

Rao, Kandala V.N., Detrisac, Carol J., Steele, Vernon E., Hawk, Ernest T., Kelloff, Gary J., McCormick, David L.

In vivo studies were conducted to compare the activity of three non-steroidal anti-inflammatory drugs as inhibitors of urinary bladder carcinogenesis induced in B6D2F1 (BDF) mice by...

Enhancement of murine Hepatocarcinogenesis by all-transretinoic acid and two synthetic retinamides (1990)

McCormick, David L., Hollister, Jacqueline L., Bagg, Bryan J., Long, Richard E.

Although retinoids have significant chemopreventive activity in many in vivo carcinogenesis models, their influence on experimental hepatocarcinogenesis has received only limited study. The present...

Anticarcinogenic activity of quinacrine in the rat mammary gland (1988)

McCormick, David L.

Mammary carcinogenesis studies were conducted to determine the chemopreventive activity of quinacrine, an antimalarial drug which suppresses the production of arachidonic acid from phospholipid...

Retinoid-tamoxifen interaction in mammary cancer chemoprevention (1986)

McCormick, David L., Moon, Richard C.

The synthetic retinoid, N-(4-hydroxyphenyl)retinamide (4-HPR), and bilateral ovariectomy act synergistically to inhibit mammary cancer induction in female rats. Two parallel studies were conducted to...

Inhibition of mammary and urinary bladder carcinogenesis by a retinoid and a maleic anhydride-divinyl ether copolymer (MVE-2) (1982)

McCormick, David L., Becci, Peter J., Moon, Richard C.

N-(4-hydroxyphenyl) retinamide (4-HPR), a synthetic retinoid, and MVE-2, a maleic anhydride-divinyl ether copolymer, were both effective inhibitors of mammary carcinogenesis induced in Sprague-Dawley...

Correlation between retinoid inhibition of N-methyl-N-nitrosourea-induced mammary carcinogenesis and levels of retinoic acid binding proteins (1982)

Mehta, Rajendra G., McCormick, David L., Cerny, Wendy L., Moon, Richard C.

A correlation was made between the ability of retinoids to suppress N-methyl-N-nitrosourea (MNU)-induced mammary carcinogenesis and the levels of cytosolic retinoic acid binding proteins (cRABP) in...

Influence of total dose and dose schedule on induction of urinary bladder cancer in the mouse by N-butyl-N-(4-hydroxy-butyl)nitrosamine (1981)

McCormick, David L., Ronan, Susan Saia, Becci, Peter J., Moon, Richard C.

Dose-response relationships in the induction of urinary bladder cancer in male C57BL/6 × DBA/2-F1 (BDF) mice by intragastric instillation of N-butyl-N-(4-hydroxybutyl)nitrosamine (OH-BBN)...

Childhood leukemia: electric and magnetic fields as possible risk factors.

Brain, Joseph D, Kavet, Robert, McCormick, David L, Poole, Charles, Silverman, Lewis B, Smith, Thomas J, ...

Numerous epidemiologic studies have reported associations between measures of power-line electric or magnetic fields (EMFs) and childhood leukemia. The basis for such associations remains...

Childhood leukemia: electric and magnetic fields as possible risk factors.

Brain, Joseph D, Kavet, Robert, McCormick, David L, Poole, Charles, Silverman, Lewis B, Smith, Thomas J, ...

Numerous epidemiologic studies have reported associations between measures of power-line electric or magnetic fields (EMFs) and childhood leukemia. The basis for such associations remains...