David M. Aanensen

Genetic Analysis of the Capsular Biosynthetic Locus from All 90 Pneumococcal Serotypes (2006)

Stephen D. Bentley, David M. Aanensen, Angeliki Mavroidi, David Saunders, Ester Rabbinowitsch, Matthew Collins, ...

Several major invasive bacterial pathogens are encapsulated. Expression of a polysaccharide capsule is essential for survival in the blood, and thus for virulence, but also is a target for host...

Multilocus Sequence Typing and Evolutionary Relationships among the Causative Agents of Melioidosis and Glanders, Burkholderia pseudomallei and Burkholderia mallei

Godoy, Daniel, Randle, Gaynor, Simpson, Andrew J., Aanensen, David M., Pitt, Tyrone L., Kinoshita, Reimi, ...

A collection of 147 isolates of Burkholderia pseudomallei, B. mallei, and B. thailandensis was characterized by multilocus sequence typing (MLST). The 128 isolates of B. pseudomallei, the causative...

eBURST: Inferring Patterns of Evolutionary Descent among Clusters of Related Bacterial Genotypes from Multilocus Sequence Typing Data

Feil, Edward J., Li, Bao C., Aanensen, David M., Hanage, William P., Spratt, Brian G.

The introduction of multilocus sequence typing (MLST) for the precise characterization of isolates of bacterial pathogens has had a marked impact on both routine epidemiological surveillance and...

Evolutionary Genetics of the Capsular Locus of Serogroup 6 Pneumococci

Mavroidi, Angeliki, Godoy, Daniel, Aanensen, David M., Robinson, D. Ashley, Hollingshead, Susan K., Spratt, Brian G.

The evolution of the capsular biosynthetic (cps) locus of serogroup 6 Streptococcus pneumoniae was investigated by analyzing sequence variation within three serotype-specific cps genes from 102...

The multilocus sequence typing network: mlst.net

Aanensen, David M., Spratt, Brian G.

The unambiguous characterization of strains of a pathogen is crucial for addressing questions relating to its epidemiology, population and evolutionary biology. Multilocus sequence typing (MLST),...

Genetic Analysis of the Capsular Biosynthetic Locus from All 90 Pneumococcal Serotypes

Bentley, Stephen D, Aanensen, David M, Mavroidi, Angeliki, Saunders, David, Rabbinowitsch, Ester, Collins, Matthew, ...

Several major invasive bacterial pathogens are encapsulated. Expression of a polysaccharide capsule is essential for survival in the blood, and thus for virulence, but also is a target for host...

Multilocus Sequence Typing and Evolutionary Relationships among the Causative Agents of Melioidosis and Glanders, Burkholderia pseudomallei and Burkholderia mallei

Godoy, Daniel, Randle, Gaynor, Simpson, Andrew J., Aanensen, David M., Pitt, Tyrone L., Kinoshita, Reimi, ...

A collection of 147 isolates of Burkholderia pseudomallei, B. mallei, and B. thailandensis was characterized by multilocus sequence typing (MLST). The 128 isolates of B. pseudomallei, the causative...

eBURST: Inferring Patterns of Evolutionary Descent among Clusters of Related Bacterial Genotypes from Multilocus Sequence Typing Data

Feil, Edward J., Li, Bao C., Aanensen, David M., Hanage, William P., Spratt, Brian G.

The introduction of multilocus sequence typing (MLST) for the precise characterization of isolates of bacterial pathogens has had a marked impact on both routine epidemiological surveillance and...

Evolutionary Genetics of the Capsular Locus of Serogroup 6 Pneumococci

Mavroidi, Angeliki, Godoy, Daniel, Aanensen, David M., Robinson, D. Ashley, Hollingshead, Susan K., Spratt, Brian G.

The evolution of the capsular biosynthetic (cps) locus of serogroup 6 Streptococcus pneumoniae was investigated by analyzing sequence variation within three serotype-specific cps genes from 102...

The multilocus sequence typing network: mlst.net

Aanensen, David M., Spratt, Brian G.

The unambiguous characterization of strains of a pathogen is crucial for addressing questions relating to its epidemiology, population and evolutionary biology. Multilocus sequence typing (MLST),...

Genetic Analysis of the Capsular Biosynthetic Locus from All 90 Pneumococcal Serotypes

Bentley, Stephen D, Aanensen, David M, Mavroidi, Angeliki, Saunders, David, Rabbinowitsch, Ester, Collins, Matthew, ...

Several major invasive bacterial pathogens are encapsulated. Expression of a polysaccharide capsule is essential for survival in the blood, and thus for virulence, but also is a target for host...

Genetic Relatedness of the Streptococcus pneumoniae Capsular Biosynthetic Loci▿ †

Mavroidi, Angeliki, Aanensen, David M., Godoy, Daniel, Skovsted, Ian C., Kaltoft, Margit S., Reeves, Peter R., ...

Streptococcus pneumoniae (the pneumococcus) produces 1 of 91 capsular polysaccharides (CPS) that define the serotype. The cps loci of 88 pneumococcal serotypes whose CPS is synthesized by the...

Predicted Functions and Linkage Specificities of the Products of the Streptococcus pneumoniae Capsular Biosynthetic Loci▿ †

Aanensen, David M., Mavroidi, Angeliki, Bentley, Stephen D., Reeves, Peter R., Spratt, Brian G.

The sequences of the capsular biosynthetic (cps) loci of 90 serotypes of Streptococcus pneumoniae have recently been determined. Bioinformatic procedures were used to predict the general functions of...