Doney, Scott C., Lima, Ivan, Moore, J. Keith, Lindsay, Keith, Behrenfeld, Michael J., Westberry, Toby K., ...
Author Posting. © Elsevier B.V., 2009. This is the author's version of the work. It is posted here by permission of Elsevier B.V. for personal use, not for redistribution. The definitive version was...
Yeast Polo-like kinase substrates are nailed with the right tools (2008)
Archambault, Vincent, Glover, David M
Abstract A platform has been built combining chemical genetics and bioinformatics to screen the proteome for physiological substrates of the Polo-like kinase in budding yeast. A novel role for this...
Archambault, Vincent, DAvino, Pier Paolo, Deery, Michael J., Lilley, Kathryn S., Glover, David M.
The conserved Polo kinase controls multiple events in mitosis and cytokinesis. Although Polo-like kinases are regulated by phosphorylation and proteolysis, control of subcellular localization plays a...
Mesoscale Variability of SeaWiFS Satellite Ocean Color: Global Patterns and Spatial Scales (2007)
Scott C. Doney, David M. Glover, Scott J. Mccue, Montserrat Fuentes
Using the semivariogram approach from geostatistics, we characterize for the first time the global patterns of mesoscale (approx. 10--200 km and days to a few weeks) ocean biological variability. The...
Vincent Archambault, Xinbei Zhao, Helen White-Cooper, David M. Glover
Polo is a conserved kinase that coordinates many events of mitosis and meiosis, but how it is regulated remains unclear. Drosophila females having only one wild-type allele of the polo kinase gene...
Vincent Archambault, Xinbei Zhao, Helen White-Cooper, Adelaide Carpenter, David M. Glover
Polo is a conserved kinase that coordinates many events of mitosis and meiosis, but how it is regulated remains unclear. Drosophila females having only one wild-type allele of the polo kinase gene...
Glover, David M., Frew, Nelson M., McCue, Scott J.
Author Posting. © Elsevier B.V., 2006. This is the author's version of the work. It is posted here by permission of Elsevier B.V. for personal use, not for redistribution. The definitive version was...
Soares, Miguel L, Haraguchi, Seiki, Torres-Padilla, Maria-Elena, Kalmar, Tibor, Carpenter, Lee, Bell, Graham, ...
Abstract Background Studies of gene function in the mouse have relied mainly on gene targeting via homologous recombination. However, this approach is difficult to apply in specific windows of time,...
Giant nuclei is essential in the cell cycle transition from meiosis to mitosis (2003)
Renault, Andrew D., Zhang, Xiao-Hua, Alphey, Luke S., Frenz, Lisa M., Glover, David M., Saunders, Robert D. C., ...
At the transition from meiosis to cleavage mitoses, Drosophila requires the cell cycle regulators encoded by the genes, giant nuclei (gnu), plutonium (plu) and pan gu (png). Embryos lacking Gnu...
Mapping and identification of essential gene functions on the X chromosome of Drosophila (2002)
Peter, Annette, Schoettler, Petra, Werner, Meike, Beinert, Nicole, Dowe, Gordon, Burkert, Peter, ...
The Drosophila melanogaster genome consists of four chromosomes that contain 165 Mb of DNA, 120 Mb of which are euchromatic. The two Drosophila Genome Projects, in collaboration with Celera Genomics...
Benos, Panayiotis V., Gatt, Melanie K., Murphy, Lee, Harris, David, Barrell, Bart, Ferraz, Concepcion, ...
We present the sequence of a contiguous 2.63 Mb of DNA extending from the tip of the X chromosome of Drosophila melanogaster. Within this sequence, we predict 277 protein coding genes, of which 94...
Benos, Panayiotis V., Gatt, Melanie K., Murphy, Lee, Harris, David, Barrell, Bart, Ferraz, Concepcion, ...
Saunders, Robert D.C., Glover, David M., Ashburner, Michael, Siden-Kiamos, Inga, Louis, Christos, Monastirioti, Maria, ...
A novel alternative to microcloning for the production of region specific chromosomal DNA is described. In this method, ‘microamplification’, single bands are dissected from polytene chromosomes...
Analysis of the Drosophila rDNA promoter by transient expression (1988)
Hayward, David C., Glover, David M.
We have examined the expression of the bacterial gene chloramphenicol acetyl transferase (CAT) under the control of the Drosophila rDNA promoter following transfection into Drosophila tissue culture...
Thesis (Ph. D.)--University of Alaska, Fairbanks, 1985.
Browne, Michael J., Read, Christopher A., Roiha, Heli, Glover, David M.
We describe a cloned segment of unique DNA from the Oregon R strain of Drosophila melanogaster that contains a short type I insertion of the kind principally found within rDNA. The predominant type I...
Transcription of the 'non-transcribed' spacer of Drosophila melanogaster rDNA (1983)
Miller, J.Ross, Hayward, David C., Glover, David M.
We have detected a set of transcripts in Drosophila melanogaster cells which are homologous to repeating elements within the ‘non-transcribed’ spacer region of rDNA. The RNA molecules range from...
The structure and expression of the preproenkephalin gene (1982)
Legon, Steve, Glover, David M., Hughes, John, Lowry, Philip J., Rigby, Peter W. J., Watson, Christine J.
Enkephalins are pentapeptides with opioid activity which are found in a wide variety of tissues. Studies of enkephalin-containing peptides from the adrenal gland have established that the mature...
We describe cloned segments of rDNA that contain short type I insertions of differing lengths. These insertions represent a coterminal subset of sequences from the right hand side of the major 5kb...
Genetic engineering : cloning DNA / David M. Glover (1980)
Incluye bibliografía e índice
Mulvihill, Daniel P., Petersen, Janni, Ohkura, Hiroyuki, Glover, David M., Hagan, Iain M.
Polo kinases execute multiple roles during cell division. The fission yeast polo related kinase Plo1 is required to assemble the mitotic spindle, the prophase actin ring that predicts the site for...
Requirement of Hsp90 for centrosomal function reflects its regulation of Polo kinase stability
De Cárcer, Guillermo, Do Carmo Avides, Maria, Lallena, María José, Glover, David M., González, Cayetano
We have previously shown that the molecular chaperone heat shock protein 90 (Hsp90) is required to ensure proper centrosome function in Drosophila and vertebrate cells. This observation led to the...
plo1+ regulates gene transcription at the M–G1 interval during the fission yeast mitotic cell cycle
Anderson, Mark, Ng, Szu Shien, Marchesi, Vanessa, MacIver, Fiona H., Stevens, Frances E., Riddell, Tracy, ...
The regulation of gene expression plays an important part in cell cycle controls. We describe the molecular machinery that co-ordinates gene transcription at the M–G1 interval during the fission...
The role of Plo1 kinase in mitotic commitment and septation in Schizosaccharomyces pombe
Tanaka, Kayoko, Petersen, Janni, MacIver, Fiona, Mulvihill, Daniel P., Glover, David M., Hagan, Iain M.
Plo1-associated casein kinase activity peaked during mitosis before septation. Phosphatase treatment abolished this activity. Mitotic Plo1 activation had a requirement for prior activation of M-phase...
Minestrini, Gianluca, Harley, Alyssa S., Glover, David M.
Pav-KLP is the Drosophila member of the MKLP1 family essential for cytokinesis. In the syncytial blastoderm embryo, GFP-Pav-KLP cyclically associates with astral, spindle, and midzone microtubules...
Benos, Panayiotis V., Gatt, Melanie K., Murphy, Lee, Harris, David, Barrell, Bart, Ferraz, Concepcion, ...
We present the sequence of a contiguous 2.63 Mb of DNA extending from the tip of the X chromosome of Drosophila melanogaster. Within this sequence, we predict 277 protein coding genes, of which 94...
Adams, Richard R., Tavares, Alvaro A.M., Salzberg, Adi, Bellen, Hugo J., Glover, David M.
Mutations in the Drosophila gene pavarotti result in the formation of abnormally large cells in the embryonic nervous system. In mitotic cycle 16, cells of pav mutant embryos undergo normal anaphase...
Barbosa, Vitor, Yamamoto, Rochele R., Henderson, Daryl S., Glover, David M.
We have cloned the Drosophila gene discs degenerate-4 (dd4) and find that it encodes a component of the γ-tubulin ring complex (γTuRC) homologous to Spc98 of budding yeast. This provides the first...
Delaney, Stephen J., Sunkel, Claudio E., Genova-Seminova, Ginka K., Davies, Jane E., Glover, David M.
We have constructed hybrid genes in which the coding region of the bacterial gene chloramphenicol acetyl transferase (CAT) has been linked to varying lengths of upstream sequences of Drosophila genes...
Roiha, Heli, Read, Christopher A., Browne, Michael J., Glover, David M.
We have examined the distribution of sequences homologous to the type I and type II rDNA insertions of Drosophila melanogaster in its sibling species. Each of the six species we have examined has...
Mapping and identification of essential gene functions on the X chromosome of Drosophila
Peter, Annette, Schöttler, Petra, Werner, Meike, Beinert, Nicole, Dowe, Gordon, Burkert, Peter, ...
The Drosophila melanogaster genome consists of four chromosomes that contain 165 Mb of DNA, 120 Mb of which are euchromatic. The two Drosophila Genome Projects, in collaboration with Celera Genomics...
Soares, Miguel L, Haraguchi, Seiki, Torres-Padilla, Maria-Elena, Kalmar, Tibor, Carpenter, Lee, Bell, Graham, ...
Spotted-dick, a zinc-finger protein of Drosophila required for expression of Orc4 and S phase
Page, Andrew R, Kovacs, Andras, Deak, Peter, Tőrők, Tibor, Kiss, Istvan, Dario, Paulo, ...
The highly condensed chromosomes and chromosome breaks in mitotic cells of a Drosophila mutant, spotted-dick/pita, are the consequence of defects in DNA replication. Reduction of levels of...
Mulvihill, Daniel P., Petersen, Janni, Ohkura, Hiroyuki, Glover, David M., Hagan, Iain M.
Polo kinases execute multiple roles during cell division. The fission yeast polo related kinase Plo1 is required to assemble the mitotic spindle, the prophase actin ring that predicts the site for...
Requirement of Hsp90 for centrosomal function reflects its regulation of Polo kinase stability
De Cárcer, Guillermo, Do Carmo Avides, Maria, Lallena, María José, Glover, David M., González, Cayetano
We have previously shown that the molecular chaperone heat shock protein 90 (Hsp90) is required to ensure proper centrosome function in Drosophila and vertebrate cells. This observation led to the...
plo1+ regulates gene transcription at the M–G1 interval during the fission yeast mitotic cell cycle
Anderson, Mark, Ng, Szu Shien, Marchesi, Vanessa, MacIver, Fiona H., Stevens, Frances E., Riddell, Tracy, ...
The regulation of gene expression plays an important part in cell cycle controls. We describe the molecular machinery that co-ordinates gene transcription at the M–G1 interval during the fission...
The role of Plo1 kinase in mitotic commitment and septation in Schizosaccharomyces pombe
Tanaka, Kayoko, Petersen, Janni, MacIver, Fiona, Mulvihill, Daniel P., Glover, David M., Hagan, Iain M.
Plo1-associated casein kinase activity peaked during mitosis before septation. Phosphatase treatment abolished this activity. Mitotic Plo1 activation had a requirement for prior activation of M-phase...
Minestrini, Gianluca, Harley, Alyssa S., Glover, David M.
Pav-KLP is the Drosophila member of the MKLP1 family essential for cytokinesis. In the syncytial blastoderm embryo, GFP-Pav-KLP cyclically associates with astral, spindle, and midzone microtubules...
Benos, Panayiotis V., Gatt, Melanie K., Murphy, Lee, Harris, David, Barrell, Bart, Ferraz, Concepcion, ...
We present the sequence of a contiguous 2.63 Mb of DNA extending from the tip of the X chromosome of Drosophila melanogaster. Within this sequence, we predict 277 protein coding genes, of which 94...
Adams, Richard R., Tavares, Alvaro A.M., Salzberg, Adi, Bellen, Hugo J., Glover, David M.
Mutations in the Drosophila gene pavarotti result in the formation of abnormally large cells in the embryonic nervous system. In mitotic cycle 16, cells of pav mutant embryos undergo normal anaphase...
Barbosa, Vitor, Yamamoto, Rochele R., Henderson, Daryl S., Glover, David M.
We have cloned the Drosophila gene discs degenerate-4 (dd4) and find that it encodes a component of the γ-tubulin ring complex (γTuRC) homologous to Spc98 of budding yeast. This provides the first...
Delaney, Stephen J., Sunkel, Claudio E., Genova-Seminova, Ginka K., Davies, Jane E., Glover, David M.
We have constructed hybrid genes in which the coding region of the bacterial gene chloramphenicol acetyl transferase (CAT) has been linked to varying lengths of upstream sequences of Drosophila genes...
Roiha, Heli, Read, Christopher A., Browne, Michael J., Glover, David M.
We have examined the distribution of sequences homologous to the type I and type II rDNA insertions of Drosophila melanogaster in its sibling species. Each of the six species we have examined has...
Mapping and identification of essential gene functions on the X chromosome of Drosophila
Peter, Annette, Schöttler, Petra, Werner, Meike, Beinert, Nicole, Dowe, Gordon, Burkert, Peter, ...
The Drosophila melanogaster genome consists of four chromosomes that contain 165 Mb of DNA, 120 Mb of which are euchromatic. The two Drosophila Genome Projects, in collaboration with Celera Genomics...
Soares, Miguel L, Haraguchi, Seiki, Torres-Padilla, Maria-Elena, Kalmar, Tibor, Carpenter, Lee, Bell, Graham, ...
The PITSLRE/CDK11p58 protein kinase promotes centrosome maturation and bipolar spindle formation
Petretti, Clotilde, Savoian, Matthew, Montembault, Emilie, Glover, David M, Prigent, Claude, Giet, Régis
The CDK11 (cyclin-dependent kinase 11) gene has an internal ribosome entry site (IRES), allowing the expression of two protein kinases. The longer 110-kDa isoform is expressed at constant levels...
Molecular Analysis of Core Kinetochore Composition and Assembly in Drosophila melanogaster
Przewloka, Marcin R., Zhang, Wei, Costa, Patricia, Archambault, Vincent, D'Avino, Pier Paolo, Lilley, Kathryn S., ...
Recruitment of Polo Kinase to the Spindle Midzone during Cytokinesis Requires the Feo/Klp3A Complex
D'Avino, Pier Paolo, Archambault, Vincent, Przewloka, Marcin R., Zhang, Wei, Lilley, Kathryn S., Laue, Ernest, ...
Archambault, Vincent, Zhao, Xinbei, White-Cooper, Helen, Carpenter, Adelaide T. C, Glover, David M
Polo is a conserved kinase that coordinates many events of mitosis and meiosis, but how it is regulated remains unclear. Drosophila females having only one wild-type allele of the polo kinase gene...
D'Avino, Pier Paolo, Savoian, Matthew S., Glover, David M.
The contractile ring is a highly dynamic structure, but how this dynamism is accomplished remains unclear. Here, we report the identification and analysis of a novel Drosophila gene, sticky (sti),...
Inoue, Yoshihiro H., Savoian, Matthew S., Suzuki, Takao, Máthé, Endre, Yamamoto, Masa-Toshi, Glover, David M.
We address the relative roles of astral and central spindle microtubules (MTs) in cytokinesis of Drosophila melanogaster primary spermatocytes. Time-lapse imaging studies reveal that the central...
Saunders, Robert D.C., Avides, Maria Do Carmo, Howard, Thomas, Gonzalez, Cayetano, Glover, David M.
abnormal spindle, a gene required for normal spindle structure and function in Drosophila melanogaster, lies immediately adjacent the gene tolloid at 96A/B. It encodes a 220-kD polypeptide with a...
Drosophila Polo Kinase Is Required for Cytokinesis
Carmena, Mar, Riparbelli, Maria Giovanna, Minestrini, Gianluca, Tavares, Álvaro M., Adams, Richard, Callaini, Giuliano, ...
A number of lines of evidence point to a predominance of cytokinesis defects in spermatogenesis in hypomorphic alleles of the Drosophila polo gene. In the pre-meiotic mitoses, cytokinesis defects...
Cullen, C. Fiona, Deák, Peter, Glover, David M., Ohkura, Hiroyuki
We describe a new Drosophila gene, mini spindles (msps) identified in a cytological screen for mitotic mutant. Mutation in msps disrupts the structural integrity of the mitotic spindle, resulting in...
Giet, Régis, McLean, Doris, Descamps, Simon, Lee, Michael J., Raff, Jordan W., Prigent, Claude, ...
Disruption of the function of the A-type Aurora kinase of Drosophila by mutation or RNAi leads to a reduction in the length of astral microtubules in syncytial embryos, larval neuroblasts, and...
Orbit, a Novel Microtubule-Associated Protein Essential for Mitosis in Drosophila melanogaster
Inoue, Yoshihiro H., Do Carmo Avides, Maria, Shiraki, Michina, Deak, Peter, Yamaguchi, Masamitsu, Nishimoto, Yoshio, ...
We describe a Drosophila gene, orbit, that encodes a conserved 165-kD microtubule-associated protein (MAP) with GTP binding motifs. Hypomorphic mutations in orbit lead to a maternal effect resulting...
Metaphase Arrest with Centromere Separation in polo Mutants of Drosophila
Donaldson, Mary M., Tavares, Álvaro A.M., Ohkura, Hiroyuki, Deak, Peter, Glover, David M.
The Drosophila gene polo encodes a conserved protein kinase known to be required to organize spindle poles and for cytokinesis. Here we report two strongly hypomorphic mutations of polo that arrest...
Aurora/Ipl1-related kinases are a conserved family of enzymes that have multiple functions during mitotic progression. Although it has been possible to use conventional genetic analysis to dissect...
Yeast Polo-like kinase substrates are nailed with the right tools
Archambault, Vincent, Glover, David M
A new approach to identifying kinase substrates reveals a novel role for yeast Polo-like kinase in mitosis
Archambault, Vincent, D’Avino, Pier Paolo, Deery, Michael J., Lilley, Kathryn S., Glover, David M.
The conserved Polo kinase controls multiple events in mitosis and cytokinesis. Although Polo-like kinases are regulated by phosphorylation and proteolysis, control of subcellular localization plays a...