David M. Langenau

Publication List Details

Period

1998 - 2007

Number

9

Co-Authors

Effects of RAS on the genesis of embryonal rhabdomyosarcoma (2007)

Langenau, David M., Keefe, Matthew D., Storer, Narie Y., Guyon, Jeffrey R., Kutok, Jeffery L., Le, Xiuning, ...

Embryonal rhabdomyosarcoma (ERMS) is a devastating cancer with specific features of muscle differentiation that can result from mutational activation of RAS family members. However, to date, RAS...

Transgenic models of T-cell acute lymphoblastic leukemia in the zebrafish / (2004)

Langenau, David M.

Thesis (Ph.D., Division of Medical Sciences (Pathology))--Harvard University, 2004.

In vivo tracking of T cell development, ablation, and engraftment in transgenic zebrafish

Langenau, David M., Ferrando, Adolfo A., Traver, David, Kutok, Jeffery L., Hezel, John-Paul D., Kanki, John P., ...

Transgenic zebrafish that express GFP under control of the T cell-specific tyrosine kinase (lck) promoter were used to analyze critical aspects of the immune system, including patterns of T cell...

Cre/lox-regulated transgenic zebrafish model with conditional myc-induced T cell acute lymphoblastic leukemia

Langenau, David M., Feng, Hui, Berghmans, Stephane, Kanki, John P., Kutok, Jeffery L., Look, A. Thomas

We have created a stable transgenic rag2-EGFP-mMyc zebrafish line that develops GFP-labeled T cell acute lymphoblastic leukemia (T-ALL), allowing visualization of the onset and spread of this...

In vivo tracking of T cell development, ablation, and engraftment in transgenic zebrafish

Langenau, David M., Ferrando, Adolfo A., Traver, David, Kutok, Jeffery L., Hezel, John-Paul D., Kanki, John P., ...

Transgenic zebrafish that express GFP under control of the T cell-specific tyrosine kinase (lck) promoter were used to analyze critical aspects of the immune system, including patterns of T cell...

Cre/lox-regulated transgenic zebrafish model with conditional myc-induced T cell acute lymphoblastic leukemia

Langenau, David M., Feng, Hui, Berghmans, Stephane, Kanki, John P., Kutok, Jeffery L., Look, A. Thomas

We have created a stable transgenic rag2-EGFP-mMyc zebrafish line that develops GFP-labeled T cell acute lymphoblastic leukemia (T-ALL), allowing visualization of the onset and spread of this...

Heat shock-inducible Cre/Lox approaches to induce diverse types of tumors and hyperplasia in transgenic zebrafish

Le, Xiuning, Langenau, David M., Keefe, Matthew D., Kutok, Jeffery L., Neuberg, Donna S., Zon, Leonard I.

RAS family members are among the most frequently mutated oncogenes in human cancers. Given the utility of zebrafish in both chemical and genetic screens, developing RAS-induced cancer models will...

Effects of RAS on the genesis of embryonal rhabdomyosarcoma

Langenau, David M., Keefe, Matthew D., Storer, Narie Y., Guyon, Jeffrey R., Kutok, Jeffery L., Le, Xiuning, ...

Embryonal rhabdomyosarcoma (ERMS) is a devastating cancer with specific features of muscle differentiation that can result from mutational activation of RAS family members. However, to date, RAS...