Feltquate, David Marc, Robinson, Harriet L.
We previously showed that intramuscular saline DNA immunizations favor the development of an IgG2a-dominant Th1 immune response, whereas gene gun DNA immunizations stimulate the production of an...
DNA vaccines: vector design, delivery, and antigen presentation (1999)
Inoculations with antigen-expressing plasmid DNAs (DNA vaccines) in the production of protective immune responses. Since the initial development of DNA vaccines more than 5 years ago, major strides...
Helper T Cell Differentiation in DNA-Immunized Mice: A Dissertation (1998)
DNA immunization, inoculation with an antigen-expressing plasmid DNA, is a new method for generating an antigen-specific immune response. At the time these investigations began, very little was known...
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Robinson, Harriet L., Boyle, Christine Margaret, Feltquate, David Marc, Morin, Merribeth J., Santoro, Joseph C., Webster, Robert G.
DNA-based immunizations have been used to analyze the ability of DNA-expressed hemagglutinin (HA) and nucleoprotein (NP) to protect BALB/c mice against a homologous influenza virus, A/PR/8/34 (H1N1),...
Feltquate, David Marc, Heaney, Shaun, Webster, Robert G., Robinson, Harriet L.
Several routes and methods of DNA immunization have been shown to generate Ab, Th cells, and CTL responses. However, few studies have directly compared the immune responses generated by different...