Development of an LSTAT Venilator. (1998)
There is a critical need for a small, portable device to provide ventilatory support to critically-ill battlefield casualties. The goal of this work is to develop a prototype ventilator suitable for...
Development of an LSTAT Ventilator. (1998)
There is a critical need for a small, portable device to provide ventilatory support to critically-ill battlefield casualties. No prior device is available which can operate independently of...
Epidural anesthesia and intrathoracic blood volume. (1993)
Warner, David O, Brichant, Jean-François, Ritman, Erik L, Rehder, Kai
To investigate how epidural anesthesia changes intrathoracic gas volume, high epidural anesthesia was administered to five pentobarbital-anesthetized dogs lying supine, and the total intrathoracic...
Chest wall motion during epidural anesthesia in dogs. (1991)
Warner, David O, Brichant, Jean-François, Ritman, Erik L, Rehder, Kai
To determine the relative contribution of rib cage and abdominal muscles to expiratory muscle activity during quiet breathing, we used lumbar epidural anesthesia in six pentobarbital...
Brichant, Jean-François, Gunst, Susan J, Warner, David O, Rehder, Kai
Volatile anesthetics are potent bronchodilators, but the site of action for the dilation is unclear. To determine the site of action of halothane, enflurane, and isoflurane on the peripheral vagal...
Muscarinic receptor subtypes in canine trachea. (1990)
Brichant, Jean-François, Warner, David O, Gunst, Susan J, Rehder, Kai
Prejunctional and postjunctional muscarinic receptor subtypes were characterized in canine trachealis muscle strips. In vitro contractile responses of muscle strips to acetylcholine or electric field...
Direct and neurally mediated effects of halothane on pulmonary resistance in vivo. (1990)
Warner, David O, Vettermann, Jörg, Brichant, Jean-François, Rehder, Kai
It has been suggested that halothane inhibits contraction of airway smooth muscle in vivo mainly by reducing reflex activity in nerves innervating the muscle with only minimal direct effects on the...
Halothane decreases both tissue and airway resistances in excised canine lungs. (1989)
Vettermann, Jörg, Warner, David O, Brichant, Jean-François, Rehder, Kai
Studies of the anesthetic effects on the airway often use pulmonary resistance (RL) as an index of airway caliber. To determine the effects of the volatile anesthetic, halothane, on tissue and airway...
Nicotine increases initial blood flow responses to local heating of human non-glabrous skin
Warner, David O, Joyner, Michael J, Charkoudian, Nisha
Nicotine affects the regulation of skin blood flow (SkBF), but the mechanisms involved are not well understood. We tested the hypothesis that acute exposure to nicotine inhibits both the initial...
Nicotine increases initial blood flow responses to local heating of human non-glabrous skin
Warner, David O, Joyner, Michael J, Charkoudian, Nisha
Nicotine affects the regulation of skin blood flow (SkBF), but the mechanisms involved are not well understood. We tested the hypothesis that acute exposure to nicotine inhibits both the initial...
Stereospecific effects of ketamine enantiomers on canine tracheal smooth muscle
Pabelick, Christina M, Rehder, Kai, Jones, Keith A, Shumway, Robin, Lindahl, Sten G E, Warner, David O
Ketamine is a potent bronchodilator which relaxes airway smooth muscle (ASM). Clinically, ketamine is used as a 1:1 racemic mixture of enantiomers that differ in their analgesic and anaesthetic...
Jones, Keith A, Perkins, William J, Lorenz, Robert R, Prakash, Y S, Sieck, Gary C, Warner, David O
Dynamic actin reorganization involving actin polymerization and depolymerization may play an important functional role in smooth muscle.This study tested the hypothesis that F-actin stabilization by...
Survey of self-assessed preparedness for clinical practice in one Croatian medical school
Bojanić, Katarina, Schears, Gregory J, Schroeder, Darrell R, Jenkins, Sarah M, Warner, David O, Sprung, Juraj
Perkins, William J., Warner, David O., Jones, Keith A.
A cultured porcine pulmonary artery (PA) model was used to examine the effects of prolonged nitric oxide (NO) treatment on the response to acutely applied NO, cGMP analog, or atrial natriuretic...