Discovering cancer genes by integrating network and functional properties (2009)
Li, Li, Zhang, Kangyu, Lee, James, Cordes, Shaun, Davis, David P, Tang, Zhijun
Abstract Background Identification of novel cancer-causing genes is one of the main goals in cancer research. The rapid accumulation of genome-wide protein-protein interaction (PPI) data in humans...
pHUSH: a single vector system for conditional gene expression (2007)
Gray, Daniel C, Hoeflich, Klaus P, Peng, Li, Gu, Zhenyu, Gogineni, Alvin, Murray, Lesley J, ...
Abstract Background Conditional expression vectors have become a valuable research tool to avoid artefacts that may result from traditional gene expression studies. However, most systems require...
Thesis (M.S.)--University of Vermont, 1994.
A field study of a program for self-directed groups. (1968)
Thesis (M.S.)--San Diego State College, 1968.
pHUSH: a single vector system for conditional gene expression
Gray, Daniel C, Hoeflich, Klaus P, Peng, Li, Gu, Zhenyu, Gogineni, Alvin, Murray, Lesley J, ...
Dul, Jeanne L., Davis, David P., Williamson, Edward K., Stevens, Fred J., Argon, Yair
In light chain (LC) amyloidosis an immunoglobulin LC assembles into fibrils that are deposited in various tissues. Little is known about how these fibrils form in vivo. We previously showed that a...
Akt inhibition promotes autophagy and sensitizes PTEN-null tumors to lysosomotropic agents
Degtyarev, Michael, De Mazière, Ann, Orr, Christine, Lin, Jie, Lee, Brian B., Tien, Janet Y., ...
Although Akt is known as a survival kinase, inhibitors of the phosphatidylinositol 3-kinase (PI3K)–Akt pathway do not always induce substantial apoptosis. We show that silencing Akt1 alone, or any...