Genetic architecture of complex traits: large phenotypic effects and pervasive epistasis. (2008)
Shao, Haifeng, Burrage, Lindsay C., Sinasac, David S., Hill, Annie E., Ernest, Sheila R., O'Brien, William, ...
The genetic architecture of complex traits underlying physiology and disease in most organisms remains elusive. We still know little about the number of genes that underlie these traits, the...
Sinasac, David S., Moriyama, Mitsuaki, Jalil, M. Abdul, Begum, Laila, Li, Meng Xian, Iijima, Mikio, ...
Adult-onset type II citrullinemia (CTLN2) is an autosomal recessive disease caused by mutations in SLC25A13, the gene encoding the mitochondrial aspartate/glutamate carrier citrin. The absence of...
Sinasac, David S., Moriyama, Mitsuaki, Jalil, M. Abdul, Begum, Laila, Li, Meng Xian, Iijima, Mikio, ...
Adult-onset type II citrullinemia (CTLN2) is an autosomal recessive disease caused by mutations in SLC25A13, the gene encoding the mitochondrial aspartate/glutamate carrier citrin. The absence of...
Genetic architecture of complex traits: Large phenotypic effects and pervasive epistasis
Shao, Haifeng, Burrage, Lindsay C., Sinasac, David S., Hill, Annie E., Ernest, Sheila R., O'Brien, William, ...
The genetic architecture of complex traits underlying physiology and disease in most organisms remains elusive. We still know little about the number of genes that underlie these traits, the...