Purinergic-mediated Ca2+ influx in Dictyostelium discoideum. (2008)
Ludlow, Melanie J., Traynor, David, Fisher, Paul R., Ennion, Steven J.
This is the author's final draft of the paper published as Cell Calcium, 2008, 44 (6), pp. 567-579. The final version is available from http://www.sciencedirect.com. The paper is also available from...
Extracellular ATP and ADP mediate Ca2+ influx in Dictyostelium discoideum. (2008)
Ludlow, Melanie J., Traynor, David, Fisher, Paul R., Ennion, Steven J.
This is the author's final draft of the paper published as Purinergic Signalling, 2008, 4 (suppl. 1), pp. S5-S6. The original publication is available at www.springerlink.com, Doi:...
Guy Francis, Mark Lishman, Vladimir Lovitskii, Michael Thrasher, David Traynor
Abstract: The biggest threat to any business is a lack of timely and accurate information. Without all the facts, businesses are pressured to make critical decisions and assess risks and...
On the effects of cycloheximide on cell motility and polarisation in Dictyostelium discoideum (2006)
Clotworthy, Margaret, Traynor, David
Abstract Background Cycloheximide is a protein synthesis inhibitor that acts specifically on the 60S subunit of eukaryotic ribosomes. It has previously been shown that a short incubation of...
Action and metabolism of the signal molecule DIF-1 in Dictyostelium. (1989)
Thesis (Ph. D.)--University of Cambridge, 1989.
Ca2+ signalling is not required for chemotaxis in Dictyostelium
Traynor, David, Milne, Jacqueline L.S., Insall, Robert H., Kay, Robert R.
Dictyostelium cells can move rapidly towards a source of cyclic-AMP (cAMP). This chemoattractant is detected by G-protein-linked receptors, which trigger a signalling cascade including a rapid influx...
Min, Junxia, Traynor, David, Stegner, Andrew L., Zhang, Lei, Hanigan, Marie H., Alexander, Hannah, ...
The drug cisplatin is widely used to treat a number of tumor types. However, resistance to the drug, which remains poorly understood, limits its usefulness. Previous work using Dictyostelium...
Ca2+ signalling is not required for chemotaxis in Dictyostelium
Traynor, David, Milne, Jacqueline L.S., Insall, Robert H., Kay, Robert R.
Dictyostelium cells can move rapidly towards a source of cyclic-AMP (cAMP). This chemoattractant is detected by G-protein-linked receptors, which trigger a signalling cascade including a rapid influx...
Min, Junxia, Traynor, David, Stegner, Andrew L., Zhang, Lei, Hanigan, Marie H., Alexander, Hannah, ...
The drug cisplatin is widely used to treat a number of tumor types. However, resistance to the drug, which remains poorly understood, limits its usefulness. Previous work using Dictyostelium...
Purinergic-mediated Ca2+ influx in Dictyostelium discoideum
Ludlow, Melanie J., Traynor, David, Fisher, Paul R., Ennion, Steven J.
The presence of five P2X-like genes (p2xA–E) in Dictyostelium suggests that nucleotides other than cAMP may act as extracellular signalling molecules in this model eukaryote. However, p2xA was...
Zhang, Xiao-Yin, Langenick, Judith, Traynor, David, Babu, M. Madan, Kay, Rob R., Patel, Ketan J.
Organisms like Dictyostelium discoideum, often referred to as DNA damage “extremophiles”, can survive exposure to extremely high doses of radiation and DNA crosslinking agents. These agents form...
Parkinson, Katie, Bolourani, Parvin, Traynor, David, Aldren, Nicola L., Kay, Robert R., Weeks, Gerald, ...
Regulated cell adhesion and motility have important roles during growth, development and tissue homeostasis. Consequently, great efforts have been made to identify genes that control these processes....